DK154085A - N-aryl-n-(4-piperidinyl)-amider samt farmaceutiske praeparater deraf - Google Patents

N-aryl-n-(4-piperidinyl)-amider samt farmaceutiske praeparater deraf Download PDF

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Publication number
DK154085A
DK154085A DK154085A DK154085A DK154085A DK 154085 A DK154085 A DK 154085A DK 154085 A DK154085 A DK 154085A DK 154085 A DK154085 A DK 154085A DK 154085 A DK154085 A DK 154085A
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DK
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Prior art keywords
amids
piperidinyl
aryl
pharmaceutical preparations
preparations
Prior art date
Application number
DK154085A
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Danish (da)
English (en)
Other versions
DK154085D0 (da
Inventor
Bao-Shan Huang
Kirsten H Deutsche
Ross C Terrell
Linas Vladas Kudzma
Nhora Lucia Lalinde
Original Assignee
Boc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boc Inc filed Critical Boc Inc
Publication of DK154085D0 publication Critical patent/DK154085D0/da
Publication of DK154085A publication Critical patent/DK154085A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK154085A 1984-04-09 1985-04-03 N-aryl-n-(4-piperidinyl)-amider samt farmaceutiske praeparater deraf DK154085A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59876984A 1984-04-09 1984-04-09
US06/707,433 US4584303A (en) 1984-04-09 1985-03-01 N-aryl-N-(4-piperidinyl)amides and pharmaceutical compositions and method employing such compounds

Publications (2)

Publication Number Publication Date
DK154085D0 DK154085D0 (da) 1985-04-03
DK154085A true DK154085A (da) 1985-10-10

Family

ID=27083145

Family Applications (1)

Application Number Title Priority Date Filing Date
DK154085A DK154085A (da) 1984-04-09 1985-04-03 N-aryl-n-(4-piperidinyl)-amider samt farmaceutiske praeparater deraf

Country Status (12)

Country Link
US (1) US4584303A (fr)
EP (1) EP0160422B1 (fr)
AU (1) AU575924B2 (fr)
CA (1) CA1281719C (fr)
DE (1) DE3585100D1 (fr)
DK (1) DK154085A (fr)
ES (2) ES8609251A1 (fr)
FI (1) FI851337L (fr)
GR (1) GR850848B (fr)
IL (1) IL74726A (fr)
NO (1) NO851393L (fr)
NZ (1) NZ211599A (fr)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
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FR2608602A1 (fr) * 1986-12-23 1988-06-24 Cerm Cent Europ Rech Mauvernay Nouvelles 3-piperidineamines ou 3-azepineamines substituees, leur preparation et leurs applications en therapeutique
US4916142A (en) * 1987-02-02 1990-04-10 Boc, Inc. N-heterocyclic-N-(4-piperidinyl)amides and pharmaceutical compositions and their use as analgesics
US4791112A (en) * 1987-02-02 1988-12-13 The Boc Group, Inc. N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds
US4954506A (en) * 1987-02-02 1990-09-04 Boc, Inc. N-heterocyclic-N-(4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds
US4912109A (en) * 1987-02-02 1990-03-27 Boc, Inc. N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compositions and methods employing such compounds
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US4791121A (en) * 1987-11-02 1988-12-13 The Boc Group, Inc. 4-phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
US5013742A (en) * 1987-11-02 1991-05-07 Boc, Inc. 4-phenyl-4-N-(phenyl) amido piperidine derivatives and pharmaceutical compositions and method employing such compounds
USRE33495E (en) * 1987-11-02 1990-12-18 Boc, Inc. Stereoselective preparation of 3-substituted-4-anilino-piperidine compounds and derivatives
US4849521A (en) * 1987-11-02 1989-07-18 Boc, Inc. Stereoselective preparation of 3-substituted-4-piperidine compounds and derivatives
US4921864A (en) * 1987-11-02 1990-05-01 Boc, Inc. 4-Phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
US4791120A (en) * 1987-12-31 1988-12-13 The Boc Group, Inc. 4-heteropentacyclic-4-[N-(phenyl)amino] piperidine derivatives and pharmaceutical compositions and method employing such compounds
DE3889897T2 (de) * 1987-12-31 1994-10-13 Ohmeda Pharma Prod 4-Heteropentacyclic-4-N-(phenyl)amido piperidin-Derivate.
US4801615A (en) * 1987-12-31 1989-01-31 The Boc Group, Inc. 4-heterohexacyclic-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
US4831192A (en) * 1987-12-31 1989-05-16 Boc, Inc. Methods of preparing 4-heteropentacyclic-4-(N-phenyl)amido) piperidine derivatives and intermediate compounds
US5019583A (en) * 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics
US5145967A (en) * 1989-04-20 1992-09-08 Anaquest, Inc. Method for preparing 4-alkoxyalkyl-4-phenylaminopiperdines and derivatives thereof
USRE34201E (en) * 1989-04-20 1993-03-23 Anaquest, Inc. N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides and pharmaceutical compositions and methods employing such compounds
KR900016129A (ko) * 1989-04-20 1990-11-12 테리 아아르 커세트 4-알콕시알킬-4-아미노페닐피페리딘 및 그들의 유도체의 제조 방법
US5053411A (en) * 1989-04-20 1991-10-01 Anaquest, Inc. N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides and pharmaceutical compositions and methods employing such compounds
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US4939161A (en) * 1989-05-12 1990-07-03 Boc, Inc. Analgesic N-aryl-N-[1-substituted-3,5-dimethyl-4-piperidinyl]amides
US4994471A (en) * 1989-05-12 1991-02-19 Boc, Inc. N-aryl-N-(1-substituted-3-alkoxy-4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds
IE903196A1 (en) * 1989-09-05 1991-03-13 Searle & Co Substituted n-benzylpiperidine amides
FR2662162B1 (fr) * 1990-05-18 1995-01-20 Adir Nouveaux derives de l'amino piperidine, de l'amino pyrrolidine et de l'amino perhydroazepine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5114714A (en) * 1990-11-29 1992-05-19 Sepracor, Inc. Methods of use and compositions of (r)-isoflurane and (r)-desflurane
US5114715A (en) * 1990-11-29 1992-05-19 Sepracor Inc. Methods of use and compositions of (s)-isoflurane and (s)-desflurane
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AU666040B2 (en) * 1992-10-28 1996-01-25 Bayer Aktiengesellschaft Substituted 1-H-3-aryl-pyrrolidine-2,4-dione derivatives
FR2705674B1 (fr) * 1993-05-26 1996-01-05 Smithkline Beecham Labo Pharma Nouveaux composés et leur procédé de préparation et leur utilisation en tant que médicaments.
EP0700385A1 (fr) * 1993-05-26 1996-03-13 Smithkline Beecham Laboratoires Pharmaceutiques Nouveaux composes
GB9316863D0 (en) * 1993-08-13 1993-09-29 Glaxo Group Ltd Chemical process
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US20110009449A1 (en) * 2007-12-19 2011-01-13 Dan Peters N-aryl-n-piperidin-4-yl-propionamide derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
ES2664801T3 (es) * 2010-09-17 2018-04-23 Mallinckrodt Llc Proceso mejorado para la preparación de un precursor de sufentanilo base
CN102249986B (zh) * 2011-02-28 2016-06-22 华东理工大学 N-苯乙基-4-苯胺基哌啶的制备方法
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FR2361880A1 (fr) * 1976-04-29 1978-03-17 Science Union & Cie Nouvelles 4-amino piperidines, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
CA1183847A (fr) * 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide; derives
CN1097151C (zh) * 1998-10-23 2002-12-25 株式会社日立制作所 燃气轮机发电设备及空气加湿器

Also Published As

Publication number Publication date
CA1281719C (fr) 1991-03-19
NZ211599A (en) 1988-11-29
ES8609251A1 (es) 1986-09-01
FI851337A0 (fi) 1985-04-03
EP0160422A1 (fr) 1985-11-06
AU4039385A (en) 1986-01-16
IL74726A0 (en) 1985-06-30
FI851337L (fi) 1985-10-10
ES8705387A1 (es) 1987-05-01
GR850848B (fr) 1985-07-05
ES552468A0 (es) 1987-05-01
ES542023A0 (es) 1986-09-01
IL74726A (en) 1989-08-15
US4584303A (en) 1986-04-22
AU575924B2 (en) 1988-08-11
DE3585100D1 (de) 1992-02-20
EP0160422B1 (fr) 1992-01-08
NO851393L (no) 1985-10-10
DK154085D0 (da) 1985-04-03

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