FI851337A0 - N-aryl-n-(4-piperidinyl)-amider och dessa innehaollande farmaceutiska kompositioner och deras anvaendning. - Google Patents

N-aryl-n-(4-piperidinyl)-amider och dessa innehaollande farmaceutiska kompositioner och deras anvaendning.

Info

Publication number
FI851337A0
FI851337A0 FI851337A FI851337A FI851337A0 FI 851337 A0 FI851337 A0 FI 851337A0 FI 851337 A FI851337 A FI 851337A FI 851337 A FI851337 A FI 851337A FI 851337 A0 FI851337 A0 FI 851337A0
Authority
FI
Finland
Prior art keywords
amider
piperidinyl
inventory
aryl
substance
Prior art date
Application number
FI851337A
Other languages
English (en)
Other versions
FI851337L (fi
Inventor
Bao-Shan Huang
Ross C Terrell
Kirsten H Deutsche
Nhora Lucia Lalinde
Linas Vladas Kudzma
Original Assignee
Boc Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boc Group Inc filed Critical Boc Group Inc
Publication of FI851337A0 publication Critical patent/FI851337A0/fi
Publication of FI851337L publication Critical patent/FI851337L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI851337A 1984-04-09 1985-04-03 N-aryl-n-(4-piperidinyl)-amider och dessa innehaollande farmaceutiska kompositioner och deras anvaendning. FI851337L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59876984A 1984-04-09 1984-04-09
US06/707,433 US4584303A (en) 1984-04-09 1985-03-01 N-aryl-N-(4-piperidinyl)amides and pharmaceutical compositions and method employing such compounds

Publications (2)

Publication Number Publication Date
FI851337A0 true FI851337A0 (fi) 1985-04-03
FI851337L FI851337L (fi) 1985-10-10

Family

ID=27083145

Family Applications (1)

Application Number Title Priority Date Filing Date
FI851337A FI851337L (fi) 1984-04-09 1985-04-03 N-aryl-n-(4-piperidinyl)-amider och dessa innehaollande farmaceutiska kompositioner och deras anvaendning.

Country Status (12)

Country Link
US (1) US4584303A (fi)
EP (1) EP0160422B1 (fi)
AU (1) AU575924B2 (fi)
CA (1) CA1281719C (fi)
DE (1) DE3585100D1 (fi)
DK (1) DK154085A (fi)
ES (2) ES8609251A1 (fi)
FI (1) FI851337L (fi)
GR (1) GR850848B (fi)
IL (1) IL74726A (fi)
NO (1) NO851393L (fi)
NZ (1) NZ211599A (fi)

Families Citing this family (59)

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FR2608602A1 (fr) * 1986-12-23 1988-06-24 Cerm Cent Europ Rech Mauvernay Nouvelles 3-piperidineamines ou 3-azepineamines substituees, leur preparation et leurs applications en therapeutique
US4791112A (en) * 1987-02-02 1988-12-13 The Boc Group, Inc. N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds
US4916142A (en) * 1987-02-02 1990-04-10 Boc, Inc. N-heterocyclic-N-(4-piperidinyl)amides and pharmaceutical compositions and their use as analgesics
US4912109A (en) * 1987-02-02 1990-03-27 Boc, Inc. N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compositions and methods employing such compounds
US4954506A (en) * 1987-02-02 1990-09-04 Boc, Inc. N-heterocyclic-N-(4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds
GB8708833D0 (en) * 1987-04-13 1987-05-20 Lilly S A E Organic compounds
US4791121A (en) * 1987-11-02 1988-12-13 The Boc Group, Inc. 4-phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
US4921864A (en) * 1987-11-02 1990-05-01 Boc, Inc. 4-Phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
US5013742A (en) * 1987-11-02 1991-05-07 Boc, Inc. 4-phenyl-4-N-(phenyl) amido piperidine derivatives and pharmaceutical compositions and method employing such compounds
US4849521A (en) * 1987-11-02 1989-07-18 Boc, Inc. Stereoselective preparation of 3-substituted-4-piperidine compounds and derivatives
USRE33495E (en) * 1987-11-02 1990-12-18 Boc, Inc. Stereoselective preparation of 3-substituted-4-anilino-piperidine compounds and derivatives
US4831192A (en) * 1987-12-31 1989-05-16 Boc, Inc. Methods of preparing 4-heteropentacyclic-4-(N-phenyl)amido) piperidine derivatives and intermediate compounds
DE3889897T2 (de) * 1987-12-31 1994-10-13 Ohmeda Pharma Prod 4-Heteropentacyclic-4-N-(phenyl)amido piperidin-Derivate.
US4791120A (en) * 1987-12-31 1988-12-13 The Boc Group, Inc. 4-heteropentacyclic-4-[N-(phenyl)amino] piperidine derivatives and pharmaceutical compositions and method employing such compounds
US4801615A (en) * 1987-12-31 1989-01-31 The Boc Group, Inc. 4-heterohexacyclic-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
US5019583A (en) * 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics
USRE34201E (en) * 1989-04-20 1993-03-23 Anaquest, Inc. N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides and pharmaceutical compositions and methods employing such compounds
US5053411A (en) * 1989-04-20 1991-10-01 Anaquest, Inc. N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides and pharmaceutical compositions and methods employing such compounds
KR900016129A (ko) * 1989-04-20 1990-11-12 테리 아아르 커세트 4-알콕시알킬-4-아미노페닐피페리딘 및 그들의 유도체의 제조 방법
US5145967A (en) * 1989-04-20 1992-09-08 Anaquest, Inc. Method for preparing 4-alkoxyalkyl-4-phenylaminopiperdines and derivatives thereof
US4994471A (en) * 1989-05-12 1991-02-19 Boc, Inc. N-aryl-N-(1-substituted-3-alkoxy-4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds
US4939161A (en) * 1989-05-12 1990-07-03 Boc, Inc. Analgesic N-aryl-N-[1-substituted-3,5-dimethyl-4-piperidinyl]amides
US5100903A (en) * 1989-05-12 1992-03-31 Anaquest, Inc. N-aryl-n-(1-substituted-3-alkoxy-4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds
IE903196A1 (en) * 1989-09-05 1991-03-13 Searle & Co Substituted n-benzylpiperidine amides
FR2662162B1 (fr) * 1990-05-18 1995-01-20 Adir Nouveaux derives de l'amino piperidine, de l'amino pyrrolidine et de l'amino perhydroazepine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5114715A (en) * 1990-11-29 1992-05-19 Sepracor Inc. Methods of use and compositions of (s)-isoflurane and (s)-desflurane
US5114714A (en) * 1990-11-29 1992-05-19 Sepracor, Inc. Methods of use and compositions of (r)-isoflurane and (r)-desflurane
US5214148A (en) * 1990-12-18 1993-05-25 Glaxo Inc. Analgesic N-phenyl-N-(3-OR1 -3-ME-4-piperidinyl)amides
US5130321A (en) * 1990-12-18 1992-07-14 Glaxo Inc. Analgesic n-phenyl-n-(3-or 1-3-me-4-piperidinyl)amides
AU666040B2 (en) * 1992-10-28 1996-01-25 Bayer Aktiengesellschaft Substituted 1-H-3-aryl-pyrrolidine-2,4-dione derivatives
FR2705674B1 (fr) * 1993-05-26 1996-01-05 Smithkline Beecham Labo Pharma Nouveaux composés et leur procédé de préparation et leur utilisation en tant que médicaments.
WO1994027967A1 (en) * 1993-05-26 1994-12-08 Smithkline Beecham Laboratoires Pharmaceutiques Novel compounds
GB9316863D0 (en) * 1993-08-13 1993-09-29 Glaxo Group Ltd Chemical process
KR19990037220A (ko) * 1997-10-31 1999-05-25 타이도 나오카타 아릴아세트산 아미드 유도체 또는 그 염 및 이를 함유하는 의약
US6677332B1 (en) 1999-05-25 2004-01-13 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
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ES2664801T3 (es) 2010-09-17 2018-04-23 Mallinckrodt Llc Proceso mejorado para la preparación de un precursor de sufentanilo base
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CA1183847A (en) * 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide derivatives
JP4099944B2 (ja) * 1998-10-23 2008-06-11 株式会社日立製作所 ガスタービン発電設備及び空気増湿装置

Also Published As

Publication number Publication date
IL74726A (en) 1989-08-15
DE3585100D1 (de) 1992-02-20
AU575924B2 (en) 1988-08-11
DK154085D0 (da) 1985-04-03
DK154085A (da) 1985-10-10
FI851337L (fi) 1985-10-10
NO851393L (no) 1985-10-10
EP0160422B1 (en) 1992-01-08
ES8705387A1 (es) 1987-05-01
ES542023A0 (es) 1986-09-01
CA1281719C (en) 1991-03-19
NZ211599A (en) 1988-11-29
GR850848B (fi) 1985-07-05
EP0160422A1 (en) 1985-11-06
ES552468A0 (es) 1987-05-01
IL74726A0 (en) 1985-06-30
ES8609251A1 (es) 1986-09-01
AU4039385A (en) 1986-01-16
US4584303A (en) 1986-04-22

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