ES2054836T3 - Compuestos de 4-heteropentaciclico-4-(fenil)amido-piperidina. - Google Patents
Compuestos de 4-heteropentaciclico-4-(fenil)amido-piperidina.Info
- Publication number
- ES2054836T3 ES2054836T3 ES88312149T ES88312149T ES2054836T3 ES 2054836 T3 ES2054836 T3 ES 2054836T3 ES 88312149 T ES88312149 T ES 88312149T ES 88312149 T ES88312149 T ES 88312149T ES 2054836 T3 ES2054836 T3 ES 2054836T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- rent
- substituted
- rental
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
UN COMPUESTO DE FORMULA Y/O SALES DE ACIDOS DE ELLOS ACEPTABLES FARMACEUTICAMENTE, EN CUYA FORMULA R1 ES UN ANILLO HETEROCICLICO NO SATURADO DE 5 ATOMOS POR ANILLO, INCLUYENDO DE 1 A 4 ATOMOS DE NITROGENO, Y DE 0 A 1 ATOMOS DE AZUFRE U OXIGENO, SIENDO DICHO ANILLO HETEROCICLICO SUBSTITUIDO O NO SUBSTITUIDO DONDE EL O CADA SUBSTITUTO SE SELECCIONA DE ALQUIL INFERIOR, ALCOXI INFERIOR, Y GRUPOS ALQUIL INFERIOR ALCOXI INFERIOR; R2 ES UN GRUPO FENIL SUSTITUIDO O NO SUSTITUIDO EN EL CUAL EL O CADA SUSTITUTO ES UN ATOMO HALOGENO; R3 ES UN ALQUIL INFERIOR O UN GRUPO ALQUIL INFERIOR ALCOXI INFERIOR; Y L ES UN GRUPO ALQUIL INFERIOR; UN GRUPO ALCOXI INFERIOR; UN GRUPO ALQUIL INFERIOR TIENIL; UN GRUPO ALQUIL INFERIOR ALCOXI INFERIOR; UN GRUPO ALQUIL INFERIOR TIAZOLIL, NO SUBSTITUIDO, O SUBSTITUIDO EN LA POSICION 4 (DEL SEMITIAZOLIL) CON UN GRUPO ALQUIL INFERIOR; UN GRUPO ALQUIL INFERIOR (4, 5 DI HIDRO - 5 - OXO - 1 H - TETRAZOL - 1 - YL), NO SUBSTIUIDO, O SUBSTITUIDO EN LA POSICION 4 ( DEL SEMI SEMITETRAZOLIL) CON UN GRUPO ALQUIL INFERIOR; UN GRUPO ALQUIL INFERIOR PIRAZOLIL; UN GRUPO ALQUIL INFERIOR PIRIDINIL; UN GRUPO ALQUIL INFERIOR OXOFENIL; UN GRUPO 2, 4 - (1H, 3H) - PIRIDINEDIONIL, DISUBSTITUIDO EN ELLA TERCERA POSICION CON GRUPOS ALQUIL DE BAJO PESO O UN GRUPO FENILO CON BAJO ALQUIL SUSTITUIDO O NO (EN EL ENLACE DEL FENIL) CON AL MENOS UN SUSTITUYENTE SELECCIONADO ENTRE ALQUILES DE BAJO PESO; GRUPOS ALCOXI DE BAJO PESO GRUPOS HALOGENADOS ALQUIL DE BAJO PESO, Y ATOMOS DE HALOGENOS, TIENE PROPIEDADES ANALGESICAS Y ANESTESICAS Y PUEDE SER USADO EN COMPOSICIONES DE ESTAS CARACTERISTICAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/139,896 US4831192A (en) | 1987-12-31 | 1987-12-31 | Methods of preparing 4-heteropentacyclic-4-(N-phenyl)amido) piperidine derivatives and intermediate compounds |
US07/139,899 US4791120A (en) | 1987-12-31 | 1987-12-31 | 4-heteropentacyclic-4-[N-(phenyl)amino] piperidine derivatives and pharmaceutical compositions and method employing such compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2054836T3 true ES2054836T3 (es) | 1994-08-16 |
Family
ID=26837644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88312149T Expired - Lifetime ES2054836T3 (es) | 1987-12-31 | 1988-12-21 | Compuestos de 4-heteropentaciclico-4-(fenil)amido-piperidina. |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0328830B1 (es) |
DE (1) | DE3889897T2 (es) |
ES (1) | ES2054836T3 (es) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4584303A (en) * | 1984-04-09 | 1986-04-22 | The Boc Group, Inc. | N-aryl-N-(4-piperidinyl)amides and pharmaceutical compositions and method employing such compounds |
-
1988
- 1988-12-21 ES ES88312149T patent/ES2054836T3/es not_active Expired - Lifetime
- 1988-12-21 DE DE19883889897 patent/DE3889897T2/de not_active Expired - Fee Related
- 1988-12-21 EP EP19880312149 patent/EP0328830B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0328830B1 (en) | 1994-06-01 |
DE3889897D1 (de) | 1994-07-07 |
EP0328830A1 (en) | 1989-08-23 |
DE3889897T2 (de) | 1994-10-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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