DK154022C - Fremgangsmaade til fremstilling af benzothiazepinderivater - Google Patents

Fremgangsmaade til fremstilling af benzothiazepinderivater

Info

Publication number
DK154022C
DK154022C DK540382A DK540382A DK154022C DK 154022 C DK154022 C DK 154022C DK 540382 A DK540382 A DK 540382A DK 540382 A DK540382 A DK 540382A DK 154022 C DK154022 C DK 154022C
Authority
DK
Denmark
Prior art keywords
procedure
acetone
benzothiazepine derivatives
preparing
mixture
Prior art date
Application number
DK540382A
Other languages
Danish (da)
English (en)
Other versions
DK540382A (da
DK154022B (da
Inventor
Mitsunori Gaino
Ikuo Iijima
Shigeru Nishimoto
Kuichiro Ikeda
Tokuo Fujii
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16373149&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK154022(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of DK540382A publication Critical patent/DK540382A/da
Publication of DK154022B publication Critical patent/DK154022B/da
Application granted granted Critical
Publication of DK154022C publication Critical patent/DK154022C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Resins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK540382A 1981-12-07 1982-12-06 Fremgangsmaade til fremstilling af benzothiazepinderivater DK154022C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19735881 1981-12-07
JP56197358A JPS5899471A (ja) 1981-12-07 1981-12-07 ベンゾチアゼピン誘導体の新規製造法

Publications (3)

Publication Number Publication Date
DK540382A DK540382A (da) 1983-06-08
DK154022B DK154022B (da) 1988-10-03
DK154022C true DK154022C (da) 1989-02-20

Family

ID=16373149

Family Applications (1)

Application Number Title Priority Date Filing Date
DK540382A DK154022C (da) 1981-12-07 1982-12-06 Fremgangsmaade til fremstilling af benzothiazepinderivater

Country Status (15)

Country Link
US (1) US4438035B1 (es)
EP (1) EP0081234B1 (es)
JP (1) JPS5899471A (es)
KR (1) KR860002034B1 (es)
AT (1) ATE15799T1 (es)
BG (1) BG38937A3 (es)
CA (1) CA1177075A (es)
DE (1) DE3266583D1 (es)
DK (1) DK154022C (es)
ES (1) ES517966A0 (es)
FI (1) FI79705C (es)
HK (1) HK95488A (es)
HU (1) HU187431B (es)
IE (1) IE54241B1 (es)
SU (1) SU1176839A3 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8316032D0 (en) * 1983-06-11 1983-07-13 Tanabe Seiyaku Co Benzothiazepine derivatives
IT1206505B (it) * 1983-07-22 1989-04-27 Schiapparelli Farma Nuovi derivati benzotiazepinonici, metodo per la loro preparazione e composizioni farmaceutiche che licontengono.
GB2154577A (en) * 1984-02-18 1985-09-11 Tanabe Seiyaku Co 1,5-benzothiazepines
IL71538A (en) * 1984-04-13 1987-07-31 Abic Ltd Process for the preparation of benzothiazepine derivatives
US4758954A (en) * 1984-07-25 1988-07-19 Computer Services Corporation Method of adjusting ticket fares
US4652561A (en) * 1986-02-26 1987-03-24 Hoffmann-La Roche Inc. Naphtho[1,2-b]-1,4-thiazepinones
IL81954A0 (en) * 1986-03-24 1987-10-20 Hoffmann La Roche Naphthothiazocinones,their manufacture and pharmaceutical compositions containing them
US4871731A (en) * 1987-10-07 1989-10-03 Marion Laboratories, Inc. Captopril and diltiazem composition and the like
US4808580A (en) * 1987-12-17 1989-02-28 Hoffmann-La Roche Inc. Naphtho[1,2-b][1,4]thiazepin-4(5H)-ones and use thereof in treatment of ischemia and blood pressure lowering
IT1226301B (it) * 1988-07-26 1990-12-27 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem.
USRE34935E (en) * 1989-01-11 1995-05-09 Synthelabo Method for preparing (+)-(2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-5H-1,5-benzothiazepine-4-one and chlorinated derivatives thereof
FR2641535B1 (fr) * 1989-01-11 1991-03-15 Synthelabo Procede de preparation de (+) - (2s, 3s)-hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4
US5128469A (en) * 1989-04-28 1992-07-07 Tanabe Seiyaku Co., Ltd. Process for preparing 1,5-benzothiazepine derivatives
JPH085869B2 (ja) * 1990-03-08 1996-01-24 田辺製薬株式会社 １，５−ベンゾチアゼピン誘導体の製法
NL9000763A (nl) * 1990-03-31 1991-10-16 Stamicarbon Werkwijze voor het bereiden van 1,5-benzothiazepine-derivaten.
IT1255545B (it) * 1992-10-23 1995-11-09 Procedimento per la preparazione di diltiazem
DK0702009T3 (da) * 1994-09-16 1999-02-01 Orion Corp Fermion Fremgangsmåde til fremstilling af farmaceutisk aktive benzothiazepinderivater
FI97725C (fi) * 1995-02-17 1997-02-10 Orion Yhtymae Oy Menetelmä diltiatseemin valmistamiseksi
WO1996038429A1 (en) * 1995-06-01 1996-12-05 Acic (Canada) Inc. Method for the manufacture of benzothiazepine derivatives
US5559229A (en) * 1995-06-01 1996-09-24 Acic (Canada) Inc. Method for the manufacture of benzothiazepine
SG50796A1 (en) * 1996-02-23 1998-07-20 Tanabe Seiyaku Co Process for preparing 1,5-benzothiazepine derivative
IL123352A0 (en) 1997-02-27 1998-09-24 Tanabe Seiyaku Co Process for preparing an optically active trans-3-substituted glycidic acid ester
US6635277B2 (en) 2000-04-12 2003-10-21 Wockhardt Limited Composition for pulsatile delivery of diltiazem and process of manufacture
JP6930693B2 (ja) * 2015-12-01 2021-09-01 サン ファーマシューティカル インダストリーズ リミテッドＳｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｉｎｄｕｓｔｒｉｅｓ Ｌｔｄ． ジルチアゼムの非経口投薬形態

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3075967A (en) * 1961-06-12 1963-01-29 Olin Mathieson Benzothiazines
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
JPS57106673A (en) * 1980-12-24 1982-07-02 Chugai Pharmaceut Co Ltd Dibenzo(b,f)(1,4)oxazepin derivative

Also Published As

Publication number Publication date
FI824165L (fi) 1983-06-08
ATE15799T1 (de) 1985-10-15
CA1177075A (en) 1984-10-30
KR860002034B1 (ko) 1986-11-17
DK540382A (da) 1983-06-08
DE3266583D1 (en) 1985-10-31
SU1176839A3 (ru) 1985-08-30
EP0081234A1 (en) 1983-06-15
JPS6317832B2 (es) 1988-04-15
IE822836L (en) 1983-06-07
ES8401953A1 (es) 1984-01-01
US4438035A (en) 1984-03-20
FI79705C (fi) 1990-02-12
HU187431B (en) 1986-01-28
BG38937A3 (en) 1986-03-14
US4438035B1 (en) 1994-07-26
FI79705B (fi) 1989-10-31
DK154022B (da) 1988-10-03
KR840002819A (ko) 1984-07-21
IE54241B1 (en) 1989-08-02
HK95488A (en) 1988-12-02
FI824165A0 (fi) 1982-12-03
JPS5899471A (ja) 1983-06-13
ES517966A0 (es) 1984-01-01
EP0081234B1 (en) 1985-09-25

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