DK1537124T3 - C-substituerede, tricykliske isoxazolinderivater og deres anvendelse som antidepressive midler - Google Patents
C-substituerede, tricykliske isoxazolinderivater og deres anvendelse som antidepressive midlerInfo
- Publication number
- DK1537124T3 DK1537124T3 DK03787817T DK03787817T DK1537124T3 DK 1537124 T3 DK1537124 T3 DK 1537124T3 DK 03787817 T DK03787817 T DK 03787817T DK 03787817 T DK03787817 T DK 03787817T DK 1537124 T3 DK1537124 T3 DK 1537124T3
- Authority
- DK
- Denmark
- Prior art keywords
- antidepressants
- substituted tricyclic
- isoxazoline derivatives
- tricyclic isoxazoline
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02078322 | 2002-08-12 | ||
PCT/EP2003/050374 WO2004016621A1 (en) | 2002-08-12 | 2003-08-12 | C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1537124T3 true DK1537124T3 (da) | 2007-10-29 |
Family
ID=31725449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03787817T DK1537124T3 (da) | 2002-08-12 | 2003-08-12 | C-substituerede, tricykliske isoxazolinderivater og deres anvendelse som antidepressive midler |
Country Status (15)
Country | Link |
---|---|
US (1) | US7465741B2 (zh) |
EP (1) | EP1537124B1 (zh) |
JP (1) | JP4681295B2 (zh) |
CN (1) | CN1329396C (zh) |
AR (1) | AR040967A1 (zh) |
AT (1) | ATE368669T1 (zh) |
AU (1) | AU2003262571B2 (zh) |
CA (1) | CA2494235C (zh) |
DE (1) | DE60315311T2 (zh) |
DK (1) | DK1537124T3 (zh) |
ES (1) | ES2290537T3 (zh) |
HK (1) | HK1080080A1 (zh) |
PT (1) | PT1537124E (zh) |
TW (1) | TW200409777A (zh) |
WO (1) | WO2004016621A1 (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1492796B1 (en) * | 2002-04-02 | 2007-09-05 | Janssen Pharmaceutica N.V. | Substituted amino isoxazoline derivatives and their use as anti-depressants. |
ES2331144T3 (es) | 2004-11-26 | 2009-12-22 | Janssen Pharmaceutica Nv | Derivados de isoxazolina-indol con actividad antipsicotica y ansiolitica mejorada. |
CN102786515B (zh) * | 2012-04-13 | 2014-07-23 | 湖南大学 | 2-(2,2-二甲基-2,3-二氢苯并呋喃-5-基)吗啉及其制备方法与应用 |
CN112374984A (zh) * | 2020-11-06 | 2021-02-19 | 苏州求索生物科技有限公司 | 一种2-溴-4-羟基苯甲醚的制备工艺 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0361577B1 (en) * | 1988-09-19 | 1993-05-05 | Akzo N.V. | Tetrahydronaphthalene and indane derivatives |
GB9318691D0 (en) * | 1993-09-09 | 1993-10-27 | Merck Sharp & Dohme | Therapeutic agents |
AU681695B2 (en) | 1993-09-15 | 1997-09-04 | Merck Sharp & Dohme Limited | Fused tricyclic heteroaromatic derivatives as dopamine receptor subtype ligands |
ATE246682T1 (de) * | 1993-12-24 | 2003-08-15 | Daiichi Suntory Pharma Co Ltd | Benzothiazinderivate |
JP3161737B2 (ja) | 1996-01-05 | 2001-04-25 | ヘキスト・マリオン・ルセル・インコーポレイテツド | CNS活性を有する4,5―ジヒドロナフト[1,2―c]イソキサゾールおよびその誘導体 |
US6187774B1 (en) | 1996-03-04 | 2001-02-13 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused heterocyclic compounds and pharmaceutical applications thereof |
WO1997047601A1 (fr) * | 1996-06-11 | 1997-12-18 | Yoshitomi Pharmaceutical Industries, Ltd. | Composes heterocycliques fusionnes et leurs utilisations medicinales |
JP2003521443A (ja) * | 1998-06-19 | 2003-07-15 | ハー・ルンドベック・アクチエゼルスカベット | 4,5,6及び7−インドール及びインドリン誘導体、その製造方法及びその使用方法 |
JP3953424B2 (ja) * | 2001-02-21 | 2007-08-08 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 抗うつ薬としてのイソキサゾリン誘導体 |
EP1492796B1 (en) * | 2002-04-02 | 2007-09-05 | Janssen Pharmaceutica N.V. | Substituted amino isoxazoline derivatives and their use as anti-depressants. |
WO2004018482A2 (en) * | 2002-08-21 | 2004-03-04 | Janssen Pharmaceutica N.V. | C6- and c9-substituted chromeno[4, 3-c]isoxazoline derivatives and their use as anti-depressants |
-
2003
- 2003-08-11 AR ARP030102900A patent/AR040967A1/es unknown
- 2003-08-11 TW TW092121939A patent/TW200409777A/zh unknown
- 2003-08-12 WO PCT/EP2003/050374 patent/WO2004016621A1/en active IP Right Grant
- 2003-08-12 CA CA2494235A patent/CA2494235C/en not_active Expired - Fee Related
- 2003-08-12 EP EP03787817A patent/EP1537124B1/en not_active Expired - Lifetime
- 2003-08-12 JP JP2004528523A patent/JP4681295B2/ja not_active Expired - Fee Related
- 2003-08-12 DK DK03787817T patent/DK1537124T3/da active
- 2003-08-12 ES ES03787817T patent/ES2290537T3/es not_active Expired - Lifetime
- 2003-08-12 AU AU2003262571A patent/AU2003262571B2/en not_active Ceased
- 2003-08-12 US US10/524,197 patent/US7465741B2/en active Active
- 2003-08-12 CN CNB03819483XA patent/CN1329396C/zh not_active Expired - Fee Related
- 2003-08-12 AT AT03787817T patent/ATE368669T1/de not_active IP Right Cessation
- 2003-08-12 PT PT03787817T patent/PT1537124E/pt unknown
- 2003-08-12 DE DE60315311T patent/DE60315311T2/de not_active Expired - Lifetime
-
2006
- 2006-01-04 HK HK06100165.3A patent/HK1080080A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
JP4681295B2 (ja) | 2011-05-11 |
TW200409777A (en) | 2004-06-16 |
ATE368669T1 (de) | 2007-08-15 |
AU2003262571B2 (en) | 2009-02-12 |
DE60315311T2 (de) | 2008-04-17 |
ES2290537T3 (es) | 2008-02-16 |
EP1537124B1 (en) | 2007-08-01 |
US7465741B2 (en) | 2008-12-16 |
CN1675222A (zh) | 2005-09-28 |
EP1537124A1 (en) | 2005-06-08 |
AR040967A1 (es) | 2005-04-27 |
US20050256119A1 (en) | 2005-11-17 |
CA2494235C (en) | 2011-10-11 |
CN1329396C (zh) | 2007-08-01 |
JP2005537304A (ja) | 2005-12-08 |
AU2003262571A1 (en) | 2004-03-03 |
DE60315311D1 (de) | 2007-09-13 |
PT1537124E (pt) | 2007-10-16 |
HK1080080A1 (zh) | 2006-04-21 |
WO2004016621A1 (en) | 2004-02-26 |
CA2494235A1 (en) | 2004-02-26 |
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