DK1524981T3 - Sammensætninger med vedvarende frigivelse indeholdende lamotrigin - Google Patents

Sammensætninger med vedvarende frigivelse indeholdende lamotrigin

Info

Publication number
DK1524981T3
DK1524981T3 DK03766343T DK03766343T DK1524981T3 DK 1524981 T3 DK1524981 T3 DK 1524981T3 DK 03766343 T DK03766343 T DK 03766343T DK 03766343 T DK03766343 T DK 03766343T DK 1524981 T3 DK1524981 T3 DK 1524981T3
Authority
DK
Denmark
Prior art keywords
sustained
compositions containing
release compositions
containing lamotrigine
lamotrigine
Prior art date
Application number
DK03766343T
Other languages
Danish (da)
English (en)
Inventor
Ian Richard Buxton
Robin Currie
Myrna A Dela-Cruz
Gary Wayne Goodson
Wlodzimierz Karolak
Mehran Maleki
Vijay Mohan Iyer
Gopal Muppirala
Alan Frank Parr
Jagdev Singh Sidhu
Robert Allen Stagner
Akunuri Venkata Vijay-Kumar
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0217492A external-priority patent/GB0217492D0/en
Priority claimed from GB0217493A external-priority patent/GB0217493D0/en
Priority claimed from GB0313801A external-priority patent/GB0313801D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK1524981T3 publication Critical patent/DK1524981T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK03766343T 2002-07-29 2003-07-28 Sammensætninger med vedvarende frigivelse indeholdende lamotrigin DK1524981T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0217492A GB0217492D0 (en) 2002-07-29 2002-07-29 Novel method of treatment
GB0217493A GB0217493D0 (en) 2002-07-29 2002-07-29 Novel methods of treatment
GB0313801A GB0313801D0 (en) 2003-06-13 2003-06-13 Novel methods of treatment
PCT/EP2003/008368 WO2004012741A1 (en) 2002-07-29 2003-07-28 Sustained release formulations comprising lamotrigine

Publications (1)

Publication Number Publication Date
DK1524981T3 true DK1524981T3 (da) 2009-06-22

Family

ID=31499035

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03766343T DK1524981T3 (da) 2002-07-29 2003-07-28 Sammensætninger med vedvarende frigivelse indeholdende lamotrigin

Country Status (29)

Country Link
US (1) US20050032799A1 (xx)
EP (1) EP1524981B1 (xx)
JP (2) JP4744142B2 (xx)
KR (1) KR100882707B1 (xx)
CN (1) CN100363007C (xx)
AR (1) AR040709A1 (xx)
AT (1) ATE424827T1 (xx)
AU (1) AU2003260336C1 (xx)
BR (1) BRPI0313148B8 (xx)
CA (1) CA2493301A1 (xx)
CO (1) CO5680405A2 (xx)
CY (1) CY1109119T1 (xx)
DE (1) DE60326590D1 (xx)
DK (1) DK1524981T3 (xx)
ES (1) ES2323268T3 (xx)
HK (1) HK1077003A1 (xx)
IL (1) IL166424A (xx)
IS (1) IS2681B (xx)
MA (1) MA27509A1 (xx)
MX (1) MXPA05001243A (xx)
MY (1) MY141049A (xx)
NO (1) NO334221B1 (xx)
NZ (1) NZ537885A (xx)
PL (1) PL213565B1 (xx)
PT (1) PT1524981E (xx)
RU (1) RU2325163C2 (xx)
SI (1) SI1524981T1 (xx)
TW (1) TWI342213B (xx)
WO (1) WO2004012741A1 (xx)

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US7939102B2 (en) * 2002-06-07 2011-05-10 Torrent Pharmaceuticals Ltd. Controlled release formulation of lamotrigine
KR100882707B1 (ko) * 2002-07-29 2009-02-06 글락소 그룹 리미티드 라모트리진을 포함하는 서방형 제제
US20050169994A1 (en) * 2003-11-25 2005-08-04 Burke Matthew D. Carvedilol free base, salts, anhydrous forms or solvates thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
WO2006023347A1 (en) * 2004-08-20 2006-03-02 Alpharma, Inc. Paroxetine formulations
DE602006016934D1 (de) * 2005-04-06 2010-10-28 Adamas Pharmaceuticals Inc Verfahren und zusammensetzungen zur behandlung von zns-erkrankungen
WO2008109343A1 (en) * 2007-03-01 2008-09-12 Memory Pharmaceuticals Corporation Methods of treating bipolar disorder and memory and/or cognitive impairment associated therewith with (+)-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyano-phenyl)-1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylate
US20090022789A1 (en) * 2007-07-18 2009-01-22 Supernus Pharmaceuticals, Inc. Enhanced formulations of lamotrigine
WO2009061513A1 (en) * 2007-11-09 2009-05-14 Thar Pharmaceuticals Crystalline forms of lamotrigine
US20090196924A1 (en) * 2008-02-04 2009-08-06 Pramod Kharwade Controlled-release lamotrigine formulations
US20100323016A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
KR20110052641A (ko) * 2008-07-18 2011-05-18 베일언트 파마슈티컬스 인터내셔널 변형 방출형 제형 및 이의 이용 방법
US20100323015A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
AU2010325960C1 (en) 2009-12-02 2015-08-06 Adamas Pharma, Llc Amantadine compositions and methods of use
WO2011086568A1 (en) * 2010-01-13 2011-07-21 Accutest Research Laboratories (I) Pvt. Ltd Controlled release composition for lamotrigine
MX2013008946A (es) * 2011-02-03 2013-10-25 Lupin Ltd Composiciones farmaceuticas orales de bepotastina de liberacion controlada.
WO2014159275A1 (en) * 2013-03-14 2014-10-02 PharmTak, Inc. Controlled-release pharmaceutical compositions comprising lamotrigine and methods of producing same
CN103920134A (zh) * 2014-05-08 2014-07-16 崔韡 一种治疗儿童眩晕的缓释片及其制备方法
RU2624229C2 (ru) * 2015-12-21 2017-07-03 Общество С Ограниченной Ответственностью "Валента-Интеллект" Таблетки клозапина с замедленным высвобождением и способ их получения
RU2613192C1 (ru) * 2016-02-18 2017-03-15 Общество С Ограниченной Ответственностью "Валента-Интеллект" Таблетки клозапина с пролонгированным высвобождением
BR112019016118A2 (pt) * 2017-02-03 2020-07-14 Jubilant Generics Limited forma farmacêutica de dosagem de suspensão oral de lamotrigina
IL272834B1 (en) 2017-08-24 2024-04-01 Adamas Pharma Llc Compositions of amantadine, their preparation, and methods of use
US20200318189A1 (en) * 2017-10-27 2020-10-08 Chang Gung Memorial Hospital, Linkou Method for assessing the risk of cutaneous adverse drug reactions induced by anti-epileptic drug lamotrigine, detection reagent thereof and use thereof
US20190247331A1 (en) 2018-02-15 2019-08-15 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
US10213394B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
US10213393B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság Composition and method for treating neurological disease
CN113214177B (zh) * 2021-04-16 2022-05-03 上海奥科达生物医药科技有限公司 一种拉莫三嗪水合物的晶体形式、其制备方法及包含其的组合物

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Also Published As

Publication number Publication date
JP2005538113A (ja) 2005-12-15
JP2011057683A (ja) 2011-03-24
IS7707A (is) 2005-02-23
MA27509A1 (fr) 2005-09-01
CA2493301A1 (en) 2004-02-12
MY141049A (en) 2010-02-25
DE60326590D1 (de) 2009-04-23
KR100882707B1 (ko) 2009-02-06
EP1524981A1 (en) 2005-04-27
WO2004012741A1 (en) 2004-02-12
BRPI0313148B8 (pt) 2021-05-25
ATE424827T1 (de) 2009-03-15
IL166424A0 (en) 2006-01-15
TW200418484A (en) 2004-10-01
RU2325163C2 (ru) 2008-05-27
CN1681509A (zh) 2005-10-12
JP4744142B2 (ja) 2011-08-10
AR040709A1 (es) 2005-04-13
MXPA05001243A (es) 2005-06-08
NO20050948L (no) 2005-02-22
ES2323268T3 (es) 2009-07-10
CY1109119T1 (el) 2014-07-02
IL166424A (en) 2010-12-30
CO5680405A2 (es) 2006-09-29
PL213565B1 (pl) 2013-03-29
PT1524981E (pt) 2009-06-17
KR20050026054A (ko) 2005-03-14
AU2003260336C1 (en) 2008-05-29
TWI342213B (en) 2011-05-21
EP1524981B1 (en) 2009-03-11
PL374982A1 (en) 2005-11-14
HK1077003A1 (en) 2006-02-03
BRPI0313148B1 (pt) 2019-08-20
IS2681B (is) 2010-09-15
AU2003260336A1 (en) 2004-02-23
CN100363007C (zh) 2008-01-23
US20050032799A1 (en) 2005-02-10
BR0313148A (pt) 2005-07-12
SI1524981T1 (sl) 2009-08-31
RU2005105353A (ru) 2005-10-27
NO334221B1 (no) 2014-01-13
NZ537885A (en) 2007-11-30

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