DK1519756T3 - Anvendelse af perfluoralkylholdige metalkomplekser som kontrastmiddel i MR-imaging til visning af intravasale tromber - Google Patents

Anvendelse af perfluoralkylholdige metalkomplekser som kontrastmiddel i MR-imaging til visning af intravasale tromber

Info

Publication number
DK1519756T3
DK1519756T3 DK03740431T DK03740431T DK1519756T3 DK 1519756 T3 DK1519756 T3 DK 1519756T3 DK 03740431 T DK03740431 T DK 03740431T DK 03740431 T DK03740431 T DK 03740431T DK 1519756 T3 DK1519756 T3 DK 1519756T3
Authority
DK
Denmark
Prior art keywords
intravasal
thrombi
perfluoroalkyl
display
contrast agent
Prior art date
Application number
DK03740431T
Other languages
Danish (da)
English (en)
Inventor
Bernd Misselwitz
Johannes Platzek
Yoko Kawata
Hanns-Joachim Weinmann
Takishi Yokawa
Ulrich Niedballa
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Application granted granted Critical
Publication of DK1519756T3 publication Critical patent/DK1519756T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK03740431T 2002-07-10 2003-07-05 Anvendelse af perfluoralkylholdige metalkomplekser som kontrastmiddel i MR-imaging til visning af intravasale tromber DK1519756T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10231799A DE10231799B4 (de) 2002-07-10 2002-07-10 Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Intravasalen Thromben
PCT/EP2003/007274 WO2004006965A2 (de) 2002-07-10 2003-07-05 Verwendung von perfluoralkylhaltigen metallkomplexen als kontrastmittel im mr-imaging zur darstellung von intravasalen thromben

Publications (1)

Publication Number Publication Date
DK1519756T3 true DK1519756T3 (da) 2007-08-13

Family

ID=30009959

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03740431T DK1519756T3 (da) 2002-07-10 2003-07-05 Anvendelse af perfluoralkylholdige metalkomplekser som kontrastmiddel i MR-imaging til visning af intravasale tromber

Country Status (23)

Country Link
EP (1) EP1519756B1 (es)
JP (1) JP2005532404A (es)
CN (1) CN1668338A (es)
AR (1) AR041187A1 (es)
AT (1) ATE361103T1 (es)
AU (2) AU2003281146A1 (es)
BR (1) BR0312552A (es)
CA (1) CA2491933A1 (es)
DE (2) DE10231799B4 (es)
DK (1) DK1519756T3 (es)
ES (1) ES2285143T3 (es)
IL (1) IL165889A0 (es)
MX (1) MXPA04012950A (es)
NO (1) NO20050679L (es)
PE (1) PE20040656A1 (es)
PL (1) PL374027A1 (es)
PT (1) PT1519756E (es)
RS (1) RS20050020A (es)
RU (1) RU2328310C2 (es)
TW (1) TW200413008A (es)
UA (1) UA79294C2 (es)
WO (2) WO2004006979A2 (es)
ZA (1) ZA200501172B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006021495A1 (de) * 2006-05-09 2007-11-15 Bayer Schering Pharma Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel zur Diagnose der Alzheimer Krankheit
CN102272102A (zh) * 2008-12-05 2011-12-07 分子制药洞察公司 锝-和铼-双(杂芳基)络合物及其使用方法
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
KR102464647B1 (ko) 2016-11-28 2022-11-08 바이엘 파마 악티엔게젤샤프트 자기 공명 영상화에 사용하기 위한 높은 이완도 가돌리늄 킬레이트 화합물
CN107445911B (zh) * 2017-06-19 2019-07-05 南京科技职业学院 一种二核含钆磁共振对比剂及其制备与应用
AU2019382881A1 (en) 2018-11-23 2021-05-20 Bayer Aktiengesellschaft Formulation of contrast media and process of preparation thereof
CN109867635A (zh) * 2019-02-14 2019-06-11 华东师范大学 一种t1型胶束磁共振成像造影剂及其制备方法
EP4059925A1 (en) 2021-03-15 2022-09-21 Bayer Aktiengesellschaft New contrast agent for use in magnetic resonance imaging
EP4335840A1 (en) 2022-09-09 2024-03-13 Bayer Aktiengesellschaft New contrast agents for use in diagnostic imaging
EP4335462A1 (en) 2022-09-09 2024-03-13 Bayer AG Contrast agents for use in diagnostic computed tomography imaging

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571498A (en) * 1994-06-02 1996-11-05 Hemagen/Pfc Emulsions of paramagnetic contrast agents for magnetic resonance imaging (MRI).
DE19603033A1 (de) * 1996-01-19 1997-07-24 Schering Ag Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
AU4753997A (en) * 1996-10-16 1998-05-11 Burnham Institute, The Magnetic resonance imaging of thrombi
DE19729013A1 (de) * 1997-07-03 1999-02-04 Schering Ag Oligomere, perfluoralkylhaltige Verbindungen, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
US6019959A (en) * 1997-07-31 2000-02-01 Schering Aktiengesellschaft Oligomeric compounds that contain perfluoroalkyl, process for their production, and their use in NMR diagnosis
DE19914101C1 (de) * 1999-03-22 2000-10-12 Schering Ag Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik
CN1626246A (zh) * 1999-07-29 2005-06-15 埃匹克斯医药品股份有限公司 通过多位点结合的寻靶多体造影剂
DE19948651B4 (de) * 1999-09-29 2006-10-05 Schering Ag Para- und diamagnetische perfluorhaltige Verbindungen enthaltende galenische Formulierungen, deren Herstellung und Verwendung
US6565828B2 (en) * 2000-04-07 2003-05-20 Bristol-Myers Squibb Company Macrocyclic chelants for metallopharmaceuticals
DE10066210B4 (de) * 2000-08-11 2008-02-28 Bayer Schering Pharma Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Plaques
DE10040381C1 (de) * 2000-08-11 2002-06-06 Schering Ag Perfluoralkylhaltige Komplexe mit Zuckerresten, Verfahren zu deren Herstellung und ihre Verwendung
DE10040858C2 (de) * 2000-08-11 2003-12-18 Schering Ag Perfluoralkylhaltige Komplexe mit polaren Resten, Verfahren zu deren Herstellung und ihre Verwendung
DE10040380B4 (de) * 2000-08-11 2006-03-09 Schering Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Plaques

Also Published As

Publication number Publication date
AR041187A1 (es) 2005-05-04
PT1519756E (pt) 2007-07-12
AU2003281150A1 (en) 2004-02-02
TW200413008A (en) 2004-08-01
NO20050679L (no) 2005-04-08
EP1519756A2 (de) 2005-04-06
RU2005103598A (ru) 2005-11-20
WO2004006965A3 (de) 2004-07-15
MXPA04012950A (es) 2005-05-16
ZA200501172B (en) 2006-04-26
DE10231799B4 (de) 2006-10-05
JP2005532404A (ja) 2005-10-27
UA79294C2 (en) 2007-06-11
RS20050020A (en) 2007-08-03
DE10231799A1 (de) 2004-02-12
DE50307180D1 (de) 2007-06-14
ATE361103T1 (de) 2007-05-15
ES2285143T3 (es) 2007-11-16
CA2491933A1 (en) 2004-01-22
PE20040656A1 (es) 2004-12-01
RU2328310C2 (ru) 2008-07-10
EP1519756B1 (de) 2007-05-02
WO2004006979A2 (de) 2004-01-22
PL374027A1 (en) 2005-09-19
AU2003281146A1 (en) 2004-02-02
CN1668338A (zh) 2005-09-14
WO2004006965A2 (de) 2004-01-22
BR0312552A (pt) 2005-04-26
IL165889A0 (en) 2006-01-15

Similar Documents

Publication Publication Date Title
FR2870125B1 (fr) Formulation du type spot-on utile en cosmetologie et en dermatologie
DK1828151T3 (da) Malonamidderivater som inhibitorer af gamma-sekretase til behandlingen af alzheimer's sygdom
DK1827412T3 (da) Sammensætninger til anvendelse i kirurgi
GB0622038D0 (en) Use of para-coumaric acid or para-hydroxycinnamic acid derivatives in cosmetic or dermatological compositions
ATE373070T1 (de) Flüssige waschmittelzusammensetzung
FI20050195A (fi) Metalliseoksen käyttö
DK1756064T3 (da) Pyrazolderivater, sammensætninger indeholdende sådanne forbindelser og anvendelsesmetoder
FR2871660B1 (fr) Manchette pour montre
DK1480615T3 (da) Superfin formoterolformulering
DE60304102D1 (de) Hautreinigungszusammensetzung
DK1858488T4 (da) Tigecyclinsammensætninger og fremgangsmåder til fremstilling deraf
DE602005026030D1 (de) Blutdruckmessgerät
DK1765376T3 (da) Topiske sammensætninger og anvendelse deraf til behandling af epitel-relaterede tilstande
DE602005012381D1 (de) Impfstoff der einen attenuierten pestivirus enthält
NO20062387L (no) Novel imaging agents
DK1519756T3 (da) Anvendelse af perfluoralkylholdige metalkomplekser som kontrastmiddel i MR-imaging til visning af intravasale tromber
EP1958945A4 (en) COMPOUNDS WITH HYDROCOUMARINSKELETTEN, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT
DK1858481T3 (da) Ophthalmologiske sammensætninger og anvendelse deraf
DK1517988T3 (da) Anvendelse af erythropoietin til vævsregenerering in vivo
EP1860089A4 (en) DIFLUORBENZENO DERIVATIVE AND NEMATIVE LIQUID CRYSTAL COMPOSITION USING THIS
DE60316636D1 (de) Mittels Additionsreaktion härtbare Organopolysiloxan-Zusammensetzungen
DE602004030435D1 (de) Verwendung eines metallkatalysators
FR2891144B1 (fr) Kit comprenant deux compositions cosmetiques
FI20041388A0 (fi) Ainakin yhden vetyisotoopin käsittävien substraattien valmistus
ITMI20030269A1 (it) Sale di cetilpiridino di un agente antiinfiammatorio