NO20050679L - Anvendelse av metallkomplekser inneholdende perfluoralkyl som kontrastmidler i magnetisk resonansbildedannelse for a fremvise intravaskulaere tromber - Google Patents

Anvendelse av metallkomplekser inneholdende perfluoralkyl som kontrastmidler i magnetisk resonansbildedannelse for a fremvise intravaskulaere tromber

Info

Publication number
NO20050679L
NO20050679L NO20050679A NO20050679A NO20050679L NO 20050679 L NO20050679 L NO 20050679L NO 20050679 A NO20050679 A NO 20050679A NO 20050679 A NO20050679 A NO 20050679A NO 20050679 L NO20050679 L NO 20050679L
Authority
NO
Norway
Prior art keywords
metal complexes
exhibit
magnetic resonance
resonance imaging
contrast agents
Prior art date
Application number
NO20050679A
Other languages
English (en)
Inventor
Hanns-Joachim Weinmann
Johannes Platzek
Ulrich Niedballa
Bernd Misselwitz
Yoko Kawata
Takishi Yokawa
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20050679L publication Critical patent/NO20050679L/no

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1806—Suspensions, emulsions, colloids, dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds

Abstract

Oppfinnelsen omhandler anvendelse av perfluoralkyl-inneholdende metallkomplekser som har en kritisk micelledannelseskonsentrasjon på < 10-3 mol/l, en hydrodynamisk micellediameter på (2 Rh) ( 1 nm og en protonrelaksivitet i plasma på (R') > 10 l/mmol's, som et kontrastmiddel brukt i MR- billeddannelse for visualisering av intravaskulære tromber.
NO20050679A 2002-07-10 2005-02-09 Anvendelse av metallkomplekser inneholdende perfluoralkyl som kontrastmidler i magnetisk resonansbildedannelse for a fremvise intravaskulaere tromber NO20050679L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10231799A DE10231799B4 (de) 2002-07-10 2002-07-10 Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Intravasalen Thromben
PCT/EP2003/007274 WO2004006965A2 (de) 2002-07-10 2003-07-05 Verwendung von perfluoralkylhaltigen metallkomplexen als kontrastmittel im mr-imaging zur darstellung von intravasalen thromben

Publications (1)

Publication Number Publication Date
NO20050679L true NO20050679L (no) 2005-04-08

Family

ID=30009959

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050679A NO20050679L (no) 2002-07-10 2005-02-09 Anvendelse av metallkomplekser inneholdende perfluoralkyl som kontrastmidler i magnetisk resonansbildedannelse for a fremvise intravaskulaere tromber

Country Status (23)

Country Link
EP (1) EP1519756B1 (no)
JP (1) JP2005532404A (no)
CN (1) CN1668338A (no)
AR (1) AR041187A1 (no)
AT (1) ATE361103T1 (no)
AU (2) AU2003281146A1 (no)
BR (1) BR0312552A (no)
CA (1) CA2491933A1 (no)
DE (2) DE10231799B4 (no)
DK (1) DK1519756T3 (no)
ES (1) ES2285143T3 (no)
IL (1) IL165889A0 (no)
MX (1) MXPA04012950A (no)
NO (1) NO20050679L (no)
PE (1) PE20040656A1 (no)
PL (1) PL374027A1 (no)
PT (1) PT1519756E (no)
RS (1) RS20050020A (no)
RU (1) RU2328310C2 (no)
TW (1) TW200413008A (no)
UA (1) UA79294C2 (no)
WO (2) WO2004006979A2 (no)
ZA (1) ZA200501172B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006021495A1 (de) * 2006-05-09 2007-11-15 Bayer Schering Pharma Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel zur Diagnose der Alzheimer Krankheit
WO2010065902A2 (en) * 2008-12-05 2010-06-10 Molecular Insight Pharmaceuticals, Inc. Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof for inhibiting psma
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
EP3544964B1 (en) 2016-11-28 2020-06-17 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
CN107445911B (zh) * 2017-06-19 2019-07-05 南京科技职业学院 一种二核含钆磁共振对比剂及其制备与应用
AU2019382881A1 (en) 2018-11-23 2021-05-20 Bayer Aktiengesellschaft Formulation of contrast media and process of preparation thereof
CN109867635A (zh) * 2019-02-14 2019-06-11 华东师范大学 一种t1型胶束磁共振成像造影剂及其制备方法
EP4059925A1 (en) 2021-03-15 2022-09-21 Bayer Aktiengesellschaft New contrast agent for use in magnetic resonance imaging
EP4335840A1 (en) 2022-09-09 2024-03-13 Bayer Aktiengesellschaft New contrast agents for use in diagnostic imaging
EP4335462A1 (en) 2022-09-09 2024-03-13 Bayer AG Contrast agents for use in diagnostic computed tomography imaging

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571498A (en) * 1994-06-02 1996-11-05 Hemagen/Pfc Emulsions of paramagnetic contrast agents for magnetic resonance imaging (MRI).
DE19603033A1 (de) * 1996-01-19 1997-07-24 Schering Ag Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
AU4753997A (en) * 1996-10-16 1998-05-11 Burnham Institute, The Magnetic resonance imaging of thrombi
DE19729013A1 (de) * 1997-07-03 1999-02-04 Schering Ag Oligomere, perfluoralkylhaltige Verbindungen, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
US6019959A (en) * 1997-07-31 2000-02-01 Schering Aktiengesellschaft Oligomeric compounds that contain perfluoroalkyl, process for their production, and their use in NMR diagnosis
DE19914101C1 (de) * 1999-03-22 2000-10-12 Schering Ag Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik
MXPA02001017A (es) * 1999-07-29 2002-08-12 Epix Medical Inc Agente multimerico de formacion de imagenes con especificidad hacia el blanco mediante su union a multiples regiones.
DE19948651B4 (de) * 1999-09-29 2006-10-05 Schering Ag Para- und diamagnetische perfluorhaltige Verbindungen enthaltende galenische Formulierungen, deren Herstellung und Verwendung
US6565828B2 (en) * 2000-04-07 2003-05-20 Bristol-Myers Squibb Company Macrocyclic chelants for metallopharmaceuticals
DE10040381C1 (de) * 2000-08-11 2002-06-06 Schering Ag Perfluoralkylhaltige Komplexe mit Zuckerresten, Verfahren zu deren Herstellung und ihre Verwendung
DE10040858C2 (de) * 2000-08-11 2003-12-18 Schering Ag Perfluoralkylhaltige Komplexe mit polaren Resten, Verfahren zu deren Herstellung und ihre Verwendung
DE10040380B4 (de) * 2000-08-11 2006-03-09 Schering Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Plaques
DE10066210B4 (de) * 2000-08-11 2008-02-28 Bayer Schering Pharma Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Plaques

Also Published As

Publication number Publication date
WO2004006965A3 (de) 2004-07-15
DE10231799A1 (de) 2004-02-12
ATE361103T1 (de) 2007-05-15
DE10231799B4 (de) 2006-10-05
DK1519756T3 (da) 2007-08-13
RU2328310C2 (ru) 2008-07-10
IL165889A0 (en) 2006-01-15
PL374027A1 (en) 2005-09-19
TW200413008A (en) 2004-08-01
ES2285143T3 (es) 2007-11-16
UA79294C2 (en) 2007-06-11
PE20040656A1 (es) 2004-12-01
DE50307180D1 (de) 2007-06-14
RS20050020A (en) 2007-08-03
WO2004006979A2 (de) 2004-01-22
EP1519756B1 (de) 2007-05-02
ZA200501172B (en) 2006-04-26
JP2005532404A (ja) 2005-10-27
WO2004006965A2 (de) 2004-01-22
AU2003281146A1 (en) 2004-02-02
CN1668338A (zh) 2005-09-14
AR041187A1 (es) 2005-05-04
EP1519756A2 (de) 2005-04-06
MXPA04012950A (es) 2005-05-16
BR0312552A (pt) 2005-04-26
PT1519756E (pt) 2007-07-12
RU2005103598A (ru) 2005-11-20
CA2491933A1 (en) 2004-01-22
AU2003281150A1 (en) 2004-02-02

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