DK1513528T3 - Farmaceutisk sammens tning indeholdende stabiliserede amorfe former af donepezilhydrochlorid - Google Patents

Farmaceutisk sammens tning indeholdende stabiliserede amorfe former af donepezilhydrochlorid

Info

Publication number
DK1513528T3
DK1513528T3 DK03741747T DK03741747T DK1513528T3 DK 1513528 T3 DK1513528 T3 DK 1513528T3 DK 03741747 T DK03741747 T DK 03741747T DK 03741747 T DK03741747 T DK 03741747T DK 1513528 T3 DK1513528 T3 DK 1513528T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical composition
donepezil hydrochloride
composition containing
amorphous forms
containing stabilized
Prior art date
Application number
DK03741747T
Other languages
Danish (da)
English (en)
Inventor
Miha Vrbinc
Kolar Alesa Puncuh
Franc Vrecer
Jordan Berta Kotar
Veronika Stangelj
Original Assignee
Krka Tovarna Zdravil D D Novo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka Tovarna Zdravil D D Novo filed Critical Krka Tovarna Zdravil D D Novo
Application granted granted Critical
Publication of DK1513528T3 publication Critical patent/DK1513528T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
DK03741747T 2002-06-19 2003-06-18 Farmaceutisk sammens tning indeholdende stabiliserede amorfe former af donepezilhydrochlorid DK1513528T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200200155A SI21223A (sl) 2002-06-19 2002-06-19 Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom
PCT/SI2003/000019 WO2004000317A1 (en) 2002-06-19 2003-06-18 Pharmaceutical composition containing stabilised amorphous form of donepezil hydrochloride

Publications (1)

Publication Number Publication Date
DK1513528T3 true DK1513528T3 (da) 2009-09-07

Family

ID=29778199

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03741747T DK1513528T3 (da) 2002-06-19 2003-06-18 Farmaceutisk sammens tning indeholdende stabiliserede amorfe former af donepezilhydrochlorid

Country Status (15)

Country Link
EP (1) EP1513528B1 (es)
AT (1) ATE431739T1 (es)
AU (1) AU2003279102A1 (es)
CY (1) CY1109314T1 (es)
DE (1) DE60327696D1 (es)
DK (1) DK1513528T3 (es)
EA (1) EA012904B1 (es)
ES (1) ES2326529T3 (es)
HR (1) HRP20041198B1 (es)
PL (1) PL212584B1 (es)
PT (1) PT1513528E (es)
RS (1) RS51824B (es)
SI (2) SI21223A (es)
UA (1) UA86573C2 (es)
WO (1) WO2004000317A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL150509A (en) 2002-07-01 2007-07-04 Joseph Kaspi Pharmaceutical preparations containing donafazil hydrochloride
IL154370A0 (en) * 2003-02-10 2003-09-17 Chemagis Ltd Solid amorphous mixtures, processes for the preparation thereof and pharmaceutical compositions containing the same
CA2552221A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Donepezil formulations
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
KR20070083679A (ko) 2004-09-29 2007-08-24 케마지스 리미티드 약학적으로 순수한 비정질 도네페닐 염산염의 제조를 위한정제된 도네페질 말레산염의 용도
ATE415148T1 (de) * 2004-10-19 2008-12-15 Krka Tovarna Zdravil D D Novo Feste pharmazeutische zusammensetzung mit donepezilhydrochlorid
WO2006063025A1 (en) * 2004-12-07 2006-06-15 Nektar Therapeutics Stable non-crystalline formulation comprising donepezil
US20060122226A1 (en) 2004-12-08 2006-06-08 Itai Adin Crystalline forms of Donepezil base
RU2401125C2 (ru) 2004-12-27 2010-10-10 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Способ стабилизации лекарственного средства против деменции
JP2007015934A (ja) * 2005-07-05 2007-01-25 Meiko Shoji Kk 温感クリーム化粧料
DE102005060377A1 (de) 2005-12-16 2007-06-21 Ratiopharm Gmbh Pharmazeutische Zusammensetzung enthaltend Donepezilhydrochlorid, Tablette hieraus und Verfahren zu deren Herstellung
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
DE102007037932A1 (de) 2007-08-11 2009-02-12 Alfred E. Tiefenbacher Gmbh & Co.Kg Donepezilhydrochlorid in amorpher Form enthaltende Tablette
DE102009041839A1 (de) * 2009-09-18 2011-03-24 Dolorgiet Gmbh & Co. Kg Donepezil-haltige Tabletten
EP2366378A1 (en) * 2010-03-01 2011-09-21 Dexcel Pharma Technologies Ltd. Sustained-release donepezil formulations
WO2011151359A1 (en) 2010-06-02 2011-12-08 Noscira, S.A. Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative
EP2502620A1 (en) 2011-03-24 2012-09-26 Krka Tovarna Zdravil, D.D., Novo Mesto Solid pharmaceutical composition comprising donepezil
WO2013135852A1 (en) 2012-03-15 2013-09-19 Boehringer Ingelheim Vetmedica Gmbh Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof
CN105377235A (zh) 2013-07-19 2016-03-02 勃林格殷格翰动物保健有限公司 含有防腐的醚化的环糊精衍生物的液体水性药物组合物
BR122019024673B1 (pt) 2013-12-04 2023-04-11 Boehringer Ingelheim Vetmedica Gmbh Composições farmacêuticas aprimoradas de pimobendan
EP3380079A4 (en) * 2015-11-25 2019-08-21 Patheon Development Services Inc. AMORPHOUS DISPERSION GRANULES AND PHARMACEUTICAL FORMS FOR ORAL USE
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
KR102372630B1 (ko) * 2019-05-15 2022-03-14 주식회사 대웅제약 고함량의 도네페질 또는 그의 염을 포함하는 경피흡수제제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
AU731282B2 (en) * 1996-06-07 2001-03-29 Eisai Co. Ltd. Polymorphs of donepezil hydrochloride and process for production
ES2310164T3 (es) * 1999-02-10 2009-01-01 Pfizer Products Inc. Dispositivo de liberacion controlada por la matriz.
CA2359945C (en) * 1999-11-12 2011-04-26 Abbott Laboratories Inhibitors of crystallization in a solid dispersion

Also Published As

Publication number Publication date
HRP20041198A2 (en) 2005-04-30
AU2003279102A1 (en) 2004-01-06
PL372116A1 (en) 2005-07-11
RS110604A (en) 2007-02-05
EP1513528B1 (en) 2009-05-20
EA012904B1 (ru) 2010-02-26
PT1513528E (pt) 2009-08-18
EP1513528A1 (en) 2005-03-16
ES2326529T3 (es) 2009-10-14
HRP20041198B1 (hr) 2013-05-31
CY1109314T1 (el) 2014-07-02
ATE431739T1 (de) 2009-06-15
EA200500040A1 (ru) 2005-06-30
SI1513528T1 (sl) 2009-10-31
PL212584B1 (pl) 2012-10-31
WO2004000317A1 (en) 2003-12-31
UA86573C2 (ru) 2009-05-12
DE60327696D1 (de) 2009-07-02
RS51824B (en) 2012-02-29
SI21223A (sl) 2003-12-31

Similar Documents

Publication Publication Date Title
CY1109314T1 (el) Φαρμακευτικη συνθεση περιεχουσα σταθεροποιημενη αμορφη μορφη της υδροχλωρικης ντονεπεζιλης
NO20051871L (no) Opioidreseptorantagonister
NO20025641D0 (no) Substituerte 1-aminoalkyl-laktamer og deres anvendelse som muscarin-reseptor-antagonister
NO20055568L (no) Substituerte 1,4-diazepiner og anvendelser derav
BR9408351A (pt) Composto composição farmacêutica processos para antagonizar o efeito de substância p e de neuroquinina a no seu sitio receptor processos para tratamento ou prevenção de dor ou nocipecção asma fibrose cistica emese e processo para a preparação de um composto
NZ507119A (en) 1-[(4-Piperidinyl)methyl]-4-piperidine derivatives useful for treating gastrointestinal disorders
EP1416933B8 (en) Substituted piperidines as modulators of the melanocortin receptor
AP2002002407A0 (en) Caspase inhibitors and uses thereof.
NO990671D0 (no) Muskarinantagonistiske etere
PE20050349A1 (es) Compuestos de aril o heteroaril amida
ATE315022T1 (de) Prostaglandinanaloga als ep4-rezeptoragonisten
RU2000129161A (ru) Производное 1-[(1-замещенного-4-пиперидинил)метил]-4-пиперидина, способ его получения, фармацевтическая композиция, содержащая указанное соединение, и промежуточный продукт
CY1107245T1 (el) Φαρμακευτικες συνθεσεις αμλοδιπινης και ατορβαστατινης
MXPA04007414A (es) Indoles sustituidos como agonistas alfa-1.
UA84146C2 (ru) Амиды пирролопиридин-2-карбоновой кислоты как ингибиторы гликогенфосфорилазы, способ их получения, фармацевтическая композиция и их применение как терапевтических агентов для лечения заболеваний
ATE519486T1 (de) Pharmazeutische zusammensetzung mit einem monoamin-neurotransmitter-wiederaufnahmehemmer und einem acetylcholinesterase-hemmer
DK0788481T3 (da) Fremgangsmåde til fremstilling af levobupivacain og analoger deraf
PL361282A1 (en) Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists
ATE403426T1 (de) Opioid-rezeptor-aktive 4-(3-hydroxyphenyl) oder 4-(3-alkoxyphenyl)-1,2,4-triazol-verbindungen
AU3581097A (en) 1,4-di-sustituted piperidines as muscarinic antagonists
NO20052491L (no) Nye vitronektinresepotr antagonistderivater, fremgangsmate til deres fremstilling, anvendelse derav som legemidler og farmasoytiske sammensetninger som inneholder de samme
EE200100520A (et) N-(2-fenüül-4-aminobutüül)-1-naftamiidid neurokiniin-1-retseptori antagonistidena
MXPA06000416A (es) Amidas azaheterociclicas novedosas utiles para tratar el dolor.
NZ543068A (en) Substituted 4-(alkyl-amide)-piperidine derivatives, processes for their preparation, and pharmaceutical compositions containing them
DE602004016177D1 (de) Methylindole und methylpyrrolopyridine als alpha-1-adrenerge agonisten