DK1480683T3 - Kontrastmiddel til nær-infraröd fluorescens og fremgangsmåde til fluorescensafdeling - Google Patents

Kontrastmiddel til nær-infraröd fluorescens og fremgangsmåde til fluorescensafdeling

Info

Publication number
DK1480683T3
DK1480683T3 DK03706606T DK03706606T DK1480683T3 DK 1480683 T3 DK1480683 T3 DK 1480683T3 DK 03706606 T DK03706606 T DK 03706606T DK 03706606 T DK03706606 T DK 03706606T DK 1480683 T3 DK1480683 T3 DK 1480683T3
Authority
DK
Denmark
Prior art keywords
represent
contrast agent
fluorescence
alkyl group
group
Prior art date
Application number
DK03706606T
Other languages
Danish (da)
English (en)
Inventor
Christin Perlitz
Kazuhiro Aikawa
Masayuki Kawakami
Hiroshi Kitaguchi
Kai Licha
Hiroaki Eguchi
Natsuko Tsuda
Original Assignee
Fujifilm Corp
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corp, Bayer Schering Pharma Ag filed Critical Fujifilm Corp
Application granted granted Critical
Publication of DK1480683T3 publication Critical patent/DK1480683T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052—Small organic molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Indole Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Endoscopes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK03706606T 2002-03-07 2003-03-07 Kontrastmiddel til nær-infraröd fluorescens og fremgangsmåde til fluorescensafdeling DK1480683T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002109794A JP2003261464A (ja) 2002-03-07 2002-03-07 近赤外蛍光造影剤および蛍光造影法
PCT/EP2003/002358 WO2003074091A2 (en) 2002-03-07 2003-03-07 Near infrared fluorescent contrast agent and method for fluorescence imaging

Publications (1)

Publication Number Publication Date
DK1480683T3 true DK1480683T3 (da) 2008-08-18

Family

ID=27785574

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03706606T DK1480683T3 (da) 2002-03-07 2003-03-07 Kontrastmiddel til nær-infraröd fluorescens og fremgangsmåde til fluorescensafdeling

Country Status (20)

Country Link
US (2) US7473415B2 (ja)
EP (1) EP1480683B1 (ja)
JP (2) JP2003261464A (ja)
KR (1) KR20040099301A (ja)
CN (1) CN100340298C (ja)
AT (1) ATE395088T1 (ja)
AU (1) AU2003208700B2 (ja)
BR (1) BR0308217A (ja)
CA (1) CA2478272A1 (ja)
DE (1) DE60320952D1 (ja)
DK (1) DK1480683T3 (ja)
ES (1) ES2305444T3 (ja)
HK (1) HK1079110A1 (ja)
MX (1) MXPA04008664A (ja)
NO (1) NO20044244L (ja)
PL (1) PL370918A1 (ja)
PT (1) PT1480683E (ja)
RU (1) RU2350355C9 (ja)
WO (1) WO2003074091A2 (ja)
ZA (1) ZA200408072B (ja)

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US7910753B2 (en) * 2004-09-10 2011-03-22 Anaspec Incorporated Cyanine dyes and their applications as luminescence quenching compounds
US8227621B2 (en) 2005-06-30 2012-07-24 Li-Cor, Inc. Cyanine dyes and methods of use
US20110262354A1 (en) * 2007-07-13 2011-10-27 Emory University Cyanine-containing compounds for cancer imaging and treatment
GB0718957D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Optical imaging agents
US20090214436A1 (en) * 2008-02-18 2009-08-27 Washington University Dichromic fluorescent compounds
US20090240143A1 (en) * 2008-03-12 2009-09-24 Mauna Kea Technologies Method and an optical probe for in vivo imaging of a mucosa in a biliary or pancreatic system and a method for selectively operating a tissue sampling of a mucosa in a biliary or pancreatic system
CN102099059B (zh) * 2008-06-13 2015-09-23 西塞医疗中心 用于癌症靶向治疗的小分子配体-药物轭合物
CN102459469A (zh) * 2009-04-17 2012-05-16 利康股份有限公司 用取代的花青染料进行荧光成像
CN101574529B (zh) * 2009-06-04 2011-04-20 中国人民解放军第三军医大学 近红外荧光化合物在制备用于淋巴结成像和血管造影的药物中的用途
AU2010286592B2 (en) 2009-08-28 2015-08-13 Visen Medical, Inc. Systems and methods for tomographic imaging in diffuse media using a hybrid inversion technique
JP2011046662A (ja) * 2009-08-28 2011-03-10 Fujifilm Corp 近赤外蛍光造影剤
JP2011046663A (ja) 2009-08-28 2011-03-10 Fujifilm Corp 近赤外蛍光造影剤
US8401619B2 (en) 2009-09-22 2013-03-19 Visen Medical, Inc. Systems and methods for virtual index-matching of diffusive media
JP5462596B2 (ja) * 2009-11-12 2014-04-02 富士フイルム株式会社 蛍光画像撮像装置
US8273875B2 (en) 2009-11-16 2012-09-25 University Of Notre Dame Du Lac High performance luminescent compounds
WO2012054784A1 (en) 2010-10-20 2012-04-26 Li-Cor, Inc. Fluorescent imaging with substituted cyanine dyes
WO2012124228A1 (ja) * 2011-03-15 2012-09-20 オリンパスメディカルシステムズ株式会社 医療装置
WO2012124227A1 (ja) * 2011-03-15 2012-09-20 オリンパスメディカルシステムズ株式会社 医療装置
EP3338617B1 (en) 2012-01-23 2020-08-19 Washington University Goggle imaging systems and devices
CN104853669B (zh) 2012-10-15 2017-07-21 文森医学公司 具有荧光及生物发光源的交叉形态加权特征的漫射介质成像的系统、方法及设备
JP6681334B2 (ja) 2013-12-31 2020-04-15 メモリアル スローン ケタリング キャンサー センター リアルタイムの蛍光源のマルチチャネル撮像のためのシステム、方法、および装置
EP3233134B1 (en) 2014-12-15 2020-03-25 Memorial Sloan-Kettering Cancer Center Cyclic peptides with enhanced nerve-binding selectivity, nanoparticles bound with said cyclic peptides, and use of same for real-time in vivo nerve tissue imaging
KR20160086481A (ko) * 2015-01-09 2016-07-20 차의과학대학교 산학협력단 신규 유기 화합물 및 이를 포함하는 근적외선 형광 조영제, 그리고 조영제의 나노입자화 방법
US10806804B2 (en) 2015-05-06 2020-10-20 Washington University Compounds having RD targeting motifs and methods of use thereof
CA3007657A1 (en) 2015-12-15 2017-06-22 Memorial Sloan Kettering Cancer Center Imaging systems and methods for tissue differentiation, e.g., for intraoperative visualization
JP6752582B2 (ja) * 2016-02-08 2020-09-09 キヤノン株式会社 光音響イメージング用造影剤
US11660354B2 (en) 2016-11-30 2023-05-30 Memorial Sloan Kettering Cancer Center Inhibitor-functionalized ultrasmall nanoparticles and methods thereof
CN115505280A (zh) 2016-12-21 2022-12-23 普罗菲尤萨股份有限公司 可聚合的近红外染料
CN111970960A (zh) 2018-03-30 2020-11-20 珀金埃尔默健康科学有限公司 使用短波红外(swir)投影层析成像对解剖器官和内含物进行3d重建的系统和方法
CN109824871B (zh) * 2019-01-08 2021-04-16 南京邮电大学 一种近红外二区荧光醌式聚合物、制备方法及其应用
EP4072598A4 (en) 2019-12-13 2024-02-21 Washington University St Louis NEAR-INFRARED FLUORESCENT DYES, FORMULATIONS AND ASSOCIATED METHODS
EP4015004A1 (en) 2020-12-18 2022-06-22 Phi Pharma SA Proteoglycan specific branched peptides
WO2023210645A1 (ja) * 2022-04-27 2023-11-02 エーザイ・アール・アンド・ディー・マネジメント株式会社 Ｉｃｇ脂質誘導体及びこれを含む脂質微粒子

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JP2001288197A (ja) * 2000-04-10 2001-10-16 Fuji Photo Film Co Ltd 蛍光ヌクレオチド
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JP2003261464A (ja) * 2002-03-07 2003-09-16 Fuji Photo Film Co Ltd 近赤外蛍光造影剤および蛍光造影法

Also Published As

Publication number Publication date
WO2003074091A3 (en) 2004-03-11
RU2350355C2 (ru) 2009-03-27
HK1079110A1 (en) 2006-03-31
RU2350355C9 (ru) 2009-05-27
JP2003261464A (ja) 2003-09-16
US20090041670A1 (en) 2009-02-12
DE60320952D1 (de) 2008-06-26
CN100340298C (zh) 2007-10-03
PL370918A1 (en) 2005-06-13
ATE395088T1 (de) 2008-05-15
MXPA04008664A (es) 2004-12-06
BR0308217A (pt) 2004-12-21
JP2005519977A (ja) 2005-07-07
ES2305444T3 (es) 2008-11-01
PT1480683E (pt) 2008-07-24
AU2003208700A1 (en) 2003-09-16
WO2003074091A2 (en) 2003-09-12
US20050226815A1 (en) 2005-10-13
CN1638810A (zh) 2005-07-13
EP1480683A2 (en) 2004-12-01
ZA200408072B (en) 2006-06-28
KR20040099301A (ko) 2004-11-26
RU2004129766A (ru) 2005-08-10
AU2003208700B2 (en) 2007-12-20
US7473415B2 (en) 2009-01-06
CA2478272A1 (en) 2003-09-12
NO20044244L (no) 2004-12-06
EP1480683B1 (en) 2008-05-14

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