DK1468996T3 - Indolderivater til behandling af CNS-sygdomme - Google Patents

Indolderivater til behandling af CNS-sygdomme

Info

Publication number
DK1468996T3
DK1468996T3 DK04012325T DK04012325T DK1468996T3 DK 1468996 T3 DK1468996 T3 DK 1468996T3 DK 04012325 T DK04012325 T DK 04012325T DK 04012325 T DK04012325 T DK 04012325T DK 1468996 T3 DK1468996 T3 DK 1468996T3
Authority
DK
Denmark
Prior art keywords
treatment
indole derivatives
cns diseases
cns
diseases
Prior art date
Application number
DK04012325T
Other languages
Danish (da)
English (en)
Inventor
Benny Bang-Andersen
Jan Kehler
Jacob Felding
Kim Andersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of DK1468996T3 publication Critical patent/DK1468996T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK04012325T 2000-06-14 2001-06-13 Indolderivater til behandling af CNS-sygdomme DK1468996T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200000919 2000-06-14
US21244500P 2000-06-16 2000-06-16
PCT/DK2001/000406 WO2001096328A1 (en) 2000-06-14 2001-06-13 Indole derivatives useful for the treatment of cns disorders

Publications (1)

Publication Number Publication Date
DK1468996T3 true DK1468996T3 (da) 2008-01-07

Family

ID=26068835

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04012325T DK1468996T3 (da) 2000-06-14 2001-06-13 Indolderivater til behandling af CNS-sygdomme

Country Status (20)

Country Link
US (2) US6890916B2 (de)
EP (1) EP1294710B1 (de)
JP (1) JP2004503550A (de)
KR (1) KR20030007967A (de)
AR (1) AR028685A1 (de)
AT (2) ATE297391T1 (de)
AU (2) AU7388101A (de)
BG (1) BG107449A (de)
CA (1) CA2411412C (de)
CZ (1) CZ200335A3 (de)
DE (2) DE60130691T2 (de)
DK (1) DK1468996T3 (de)
ES (2) ES2290587T3 (de)
HR (1) HRP20021008A2 (de)
HU (1) HUP0301735A2 (de)
NO (1) NO323236B1 (de)
NZ (1) NZ523076A (de)
PT (2) PT1468996E (de)
SG (1) SG148840A1 (de)
WO (1) WO2001096328A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
EP1468996B1 (de) * 2000-06-14 2007-09-26 H. Lundbeck A/S Indolderivate zur Behandlung von Erkrankungen des Zentralnervensystems
ES2172436B1 (es) 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
WO2003102097A1 (en) * 2002-05-31 2003-12-11 H. Lundbeck A/S The hydrochloride of (s)-(+)-3-[1-[2-(1-acetyl-2,3-dihydro-1h-indol-3-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl]-6-chloro-1h-indole
WO2004020437A1 (en) * 2002-08-29 2004-03-11 H. Lundbeck A/S S-(+)-3-{1-[2-(2,3-dihydro-1h-indol-3-yl)ethyl]-3,6-dihydro-2h-pyridin-4-yl}-6-chloro-1h-indole and acid addition salts thereof
GB0306604D0 (en) * 2003-03-21 2003-04-30 Curidium Ltd Second medical use
WO2004108671A1 (en) * 2003-06-06 2004-12-16 Suven Life Sciences Limited Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them
GB0708186D0 (en) * 2007-04-27 2007-06-06 Merck Sharp & Dohme Therapeutic compounds
SE531698C2 (sv) 2007-07-12 2009-07-07 Respiratorius Ab Nya bronkdilaterande a,b-omättade amider

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9202915D0 (en) * 1992-02-12 1992-03-25 Wellcome Found Chemical compounds
ZA9711376B (en) * 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
WO1999010346A1 (en) * 1997-08-22 1999-03-04 Eli Lilly And Company Limited Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands
GB9718833D0 (en) * 1997-09-04 1997-11-12 Merck Sharp & Dohme Therapeutic agents
GB9810886D0 (en) * 1998-05-13 1998-07-22 Lilly Industries Ltd Pharmaceutical compounds
GB9825413D0 (en) * 1998-11-19 1999-01-13 Lilly Co Eli Pharmaceutical compounds
AU2494300A (en) * 1999-01-07 2000-07-24 American Home Products Corporation 3,4-dihydro-2h-benzo(1,4)oxazine derivatives
EP1200072A2 (de) * 1999-05-12 2002-05-02 Solvay Pharmaceuticals B.V. Verfahren zur behandlung von psychotischen erkrankungen
CN1158258C (zh) * 1999-06-24 2004-07-21 东丽株式会社 肾上腺素能α1B受体拮抗药
GB2362381A (en) * 2000-05-18 2001-11-21 Lilly Co Eli Pharmaceutically active indolyl-piperidines

Also Published As

Publication number Publication date
JP2004503550A (ja) 2004-02-05
US6890916B2 (en) 2005-05-10
HUP0301735A2 (hu) 2003-08-28
DE60111379T2 (de) 2006-03-16
PT1468996E (pt) 2007-11-28
CA2411412C (en) 2008-09-02
EP1294710A1 (de) 2003-03-26
US20030191133A1 (en) 2003-10-09
BG107449A (bg) 2003-09-30
CZ200335A3 (cs) 2003-04-16
ATE374197T1 (de) 2007-10-15
US20050176729A1 (en) 2005-08-11
PT1294710E (pt) 2005-10-31
ATE297391T1 (de) 2005-06-15
AR028685A1 (es) 2003-05-21
AU2001273881B8 (en) 2006-02-09
NO20026005D0 (no) 2002-12-13
EP1294710B1 (de) 2005-06-08
KR20030007967A (ko) 2003-01-23
AU2001273881B2 (en) 2005-12-22
DE60130691T2 (de) 2008-07-17
WO2001096328A1 (en) 2001-12-20
US7276508B2 (en) 2007-10-02
DE60130691D1 (de) 2007-11-08
DE60111379D1 (de) 2005-07-14
NO20026005L (no) 2002-12-13
ES2290587T3 (es) 2008-02-16
CA2411412A1 (en) 2001-12-20
NZ523076A (en) 2004-09-24
HRP20021008A2 (en) 2005-02-28
SG148840A1 (en) 2009-01-29
NO323236B1 (no) 2007-02-05
AU7388101A (en) 2001-12-24
ES2243508T3 (es) 2005-12-01

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