DK146205C - Analogifremgangsmaade til fremstilling af 8alfa-ergolin-i-derivater - Google Patents
Analogifremgangsmaade til fremstilling af 8alfa-ergolin-i-derivaterInfo
- Publication number
- DK146205C DK146205C DK562376A DK562376A DK146205C DK 146205 C DK146205 C DK 146205C DK 562376 A DK562376 A DK 562376A DK 562376 A DK562376 A DK 562376A DK 146205 C DK146205 C DK 146205C
- Authority
- DK
- Denmark
- Prior art keywords
- 8alfa
- ergolin
- derivatives
- preparation
- analogy procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1668075A CH620441A5 (en) | 1975-12-23 | 1975-12-23 | Process for the preparation of novel ergoline compounds |
| CH1668075 | 1975-12-23 | ||
| CH618876 | 1976-05-18 | ||
| CH618876 | 1976-05-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK562376A DK562376A (da) | 1977-06-24 |
| DK146205B DK146205B (da) | 1983-07-25 |
| DK146205C true DK146205C (da) | 1983-12-27 |
Family
ID=25699142
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK562376A DK146205C (da) | 1975-12-23 | 1976-12-14 | Analogifremgangsmaade til fremstilling af 8alfa-ergolin-i-derivater |
| DK554179A DK554179A (da) | 1975-12-23 | 1979-12-21 | Fremgangsmaade til fremstilling af ergolinderivater |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK554179A DK554179A (da) | 1975-12-23 | 1979-12-21 | Fremgangsmaade til fremstilling af ergolinderivater |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4348391A (fr) |
| JP (1) | JPS5278900A (fr) |
| AU (1) | AU514288B2 (fr) |
| CA (1) | CA1092100A (fr) |
| DE (1) | DE2656344A1 (fr) |
| DK (2) | DK146205C (fr) |
| ES (1) | ES454442A1 (fr) |
| FI (1) | FI763587A (fr) |
| FR (1) | FR2336135A1 (fr) |
| GB (1) | GB1567484A (fr) |
| HK (1) | HK3483A (fr) |
| IE (1) | IE44242B1 (fr) |
| IL (1) | IL51133A (fr) |
| MY (1) | MY8400060A (fr) |
| NL (1) | NL7614018A (fr) |
| NZ (1) | NZ182934A (fr) |
| PH (1) | PH14035A (fr) |
| PT (1) | PT66006B (fr) |
| SE (1) | SE432253B (fr) |
| SG (1) | SG63382G (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE889713A (fr) * | 1980-07-25 | 1982-01-25 | Sandoz Sa | Nouveaux derives de l'ergoline, leur preparation et leur application comme medicaments |
| CH654838A5 (fr) * | 1980-07-25 | 1986-03-14 | Sandoz Ag | Ergolinderivate, verfahren zu deren herstellung, diese enthaltende pharmazeutische zusammensetzungen. |
| CH644606A5 (de) * | 1980-09-23 | 1984-08-15 | Sandoz Ag | Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten. |
| DE3101535A1 (de) * | 1981-01-14 | 1982-08-12 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
| GB2112382B (en) * | 1981-11-06 | 1985-03-06 | Erba Farmitalia | Ergoline derivatives |
| DE3151912A1 (de) * | 1981-12-23 | 1983-06-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
| DE3216870A1 (de) * | 1982-05-03 | 1983-11-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Pharmazeutische zubereitungen mit zytostatischer wirkung |
| CH652719A5 (en) * | 1983-02-16 | 1985-11-29 | Sandoz Ag | Ergoline derivatives, their preparation and use |
| HU196399B (en) * | 1983-02-16 | 1988-11-28 | Sandoz Ag | Process for producing ergoline derivatives and pharmaceutical compositions comprising such compounds |
| HU197569B (en) * | 1984-01-12 | 1989-04-28 | Sandoz Ag | Process for producing 8alpha-acylaminoergoline derivatives and pharmaceuticals comprising such compounds |
| US4675322A (en) * | 1984-12-10 | 1987-06-23 | Eli Lilly And Company | 1-Substituted-6-n-propyl-8β-methylthio-methylergolines |
| CH666035A5 (de) * | 1984-12-24 | 1988-06-30 | Sandoz Ag | 8-alpha-acylaminoergolene. |
| HU193317B (en) * | 1985-06-12 | 1987-09-28 | Richter Gedeon Vegyeszet | Process for producing 2-bromo-alpha-ergochristin |
| US4801712A (en) * | 1985-06-24 | 1989-01-31 | Eli Lilly And Company | 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity |
| DE3535929A1 (de) * | 1985-10-04 | 1987-04-09 | Schering Ag | 1,2-disubstituierte ergolinderivate |
| HU196598B (en) * | 1986-04-25 | 1988-12-28 | Richter Gedeon Vegyeszet | Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds |
| GB8615471D0 (en) * | 1986-06-25 | 1986-07-30 | Erba Farmitalia | T-butyl ergoline derivatives |
| US4798834A (en) * | 1987-08-31 | 1989-01-17 | Eli Lilly And Company | Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement |
| AT392945B (de) * | 1988-06-27 | 1991-07-10 | Gerhard Mader Ges M B H Ing | Lager- und transportbehaelter fuer schuettgueter und lose materialien |
| IT1232692B (it) * | 1989-08-04 | 1992-03-04 | Poli Ind Chimica Spa | Derivati ergolinici con attivita' dopaminergica |
| AU2635599A (en) * | 1999-03-17 | 2000-10-04 | Eugen Eigenmann | Use of prolactin inhibitors for the treatment of fertility problems in animal species |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2533698A (en) * | 1950-12-12 | Urethanes containing the lysergic | ||
| US3245996A (en) * | 1966-04-12 | Cyanoethyl lysergol | ||
| US3232943A (en) * | 1966-02-01 | Cyanoethyl ergolene and ergoline derivatives | ||
| US3218323A (en) * | 1965-11-16 | Esters of i,g-dimethyl-b-ergolenyl carbamic acid | ||
| US3270020A (en) * | 1966-08-30 | Dihydro ergocornine | ||
| US3185695A (en) * | 1965-05-25 | Dbwethyl-ergoline ii derivatives | ||
| CH415658A (de) * | 1962-06-18 | 1966-06-30 | Sandoz Ag | Verfahren zur Herstellung von neuen Urethanen |
| CH507248A (de) * | 1967-03-16 | 1971-05-15 | Spofa Vereinigte Pharma Werke | Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure |
| US3920664A (en) * | 1972-07-21 | 1975-11-18 | Lilly Co Eli | D-2-halo-6-alkyl-8-substituted ergolines and related compounds |
| US3880856A (en) * | 1973-06-29 | 1975-04-29 | Lilly Co Eli | Ergoline dimers |
| CS171480B1 (fr) * | 1974-03-19 | 1976-10-29 | ||
| GB1517973A (en) * | 1974-07-19 | 1978-07-19 | Sandoz Ltd | 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i |
| CH605936A5 (en) * | 1974-07-19 | 1978-10-13 | Sandoz Ag | 8-Alpha-(Amino-or cyanomethyl)-ergoline derivs |
| US3904757A (en) * | 1974-08-08 | 1975-09-09 | Lilly Co Eli | Treatment of parkinsonism |
| US3922347A (en) * | 1974-12-19 | 1975-11-25 | Lilly Co Eli | Method of inhibiting prolactin secretion with 8-acylaminoergolenes |
-
1976
- 1976-12-13 DE DE19762656344 patent/DE2656344A1/de active Granted
- 1976-12-14 FI FI763587A patent/FI763587A/fi not_active Application Discontinuation
- 1976-12-14 DK DK562376A patent/DK146205C/da not_active IP Right Cessation
- 1976-12-15 SE SE7614085A patent/SE432253B/xx not_active IP Right Cessation
- 1976-12-17 NL NL7614018A patent/NL7614018A/xx not_active Application Discontinuation
- 1976-12-21 NZ NZ182934A patent/NZ182934A/xx unknown
- 1976-12-21 AU AU20793/76A patent/AU514288B2/en not_active Expired
- 1976-12-21 PH PH19276A patent/PH14035A/en unknown
- 1976-12-21 IE IE2803/76A patent/IE44242B1/en unknown
- 1976-12-21 IL IL51133A patent/IL51133A/xx unknown
- 1976-12-21 ES ES454442A patent/ES454442A1/es not_active Expired
- 1976-12-21 CA CA268,415A patent/CA1092100A/fr not_active Expired
- 1976-12-21 GB GB53303/76A patent/GB1567484A/en not_active Expired
- 1976-12-22 JP JP51153514A patent/JPS5278900A/ja active Granted
- 1976-12-22 FR FR7638697A patent/FR2336135A1/fr active Granted
- 1976-12-22 PT PT66006A patent/PT66006B/fr unknown
-
1979
- 1979-12-21 DK DK554179A patent/DK554179A/da unknown
-
1980
- 1980-09-22 US US06/189,068 patent/US4348391A/en not_active Expired - Lifetime
-
1982
- 1982-12-23 SG SG633/82A patent/SG63382G/en unknown
-
1983
- 1983-01-20 HK HK34/83A patent/HK3483A/xx unknown
-
1984
- 1984-12-30 MY MY60/84A patent/MY8400060A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2656344A1 (de) | 1977-07-07 |
| NL7614018A (nl) | 1977-06-27 |
| SE7614085L (sv) | 1977-06-24 |
| MY8400060A (en) | 1984-12-31 |
| ES454442A1 (es) | 1978-03-01 |
| HK3483A (en) | 1983-01-20 |
| SE432253B (sv) | 1984-03-26 |
| PT66006B (fr) | 1978-07-06 |
| SG63382G (en) | 1983-09-09 |
| US4348391A (en) | 1982-09-07 |
| IL51133A (en) | 1981-11-30 |
| FR2336135B1 (fr) | 1980-03-07 |
| IE44242B1 (en) | 1981-09-23 |
| PT66006A (fr) | 1977-01-01 |
| IL51133A0 (en) | 1977-02-28 |
| DK562376A (da) | 1977-06-24 |
| DK146205B (da) | 1983-07-25 |
| PH14035A (en) | 1980-12-12 |
| JPS5278900A (en) | 1977-07-02 |
| JPS6133031B2 (fr) | 1986-07-31 |
| FR2336135A1 (fr) | 1977-07-22 |
| AU514288B2 (en) | 1981-02-05 |
| FI763587A (fr) | 1977-06-24 |
| CA1092100A (fr) | 1980-12-23 |
| AU2079376A (en) | 1978-06-29 |
| DE2656344C2 (fr) | 1990-11-08 |
| DK554179A (da) | 1979-12-21 |
| GB1567484A (en) | 1980-05-14 |
| NZ182934A (en) | 1978-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |