DK142372C - Fremgangsmaade til fremstilling af androstan-17-on-derivater - Google Patents

Fremgangsmaade til fremstilling af androstan-17-on-derivater

Info

Publication number
DK142372C
DK142372C DK323677A DK323677A DK142372C DK 142372 C DK142372 C DK 142372C DK 323677 A DK323677 A DK 323677A DK 323677 A DK323677 A DK 323677A DK 142372 C DK142372 C DK 142372C
Authority
DK
Denmark
Prior art keywords
androstan
derivatives
procedure
preparation
Prior art date
Application number
DK323677A
Other languages
Danish (da)
English (en)
Other versions
DK142372B (da
DK323677A (da
Inventor
A Weber
M Kennecke
H Dahl
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK323677A publication Critical patent/DK323677A/da
Priority to DK238478A priority Critical patent/DK238478A/da
Priority to DK238378A priority patent/DK238378A/da
Priority to DK238278A priority patent/DK238278A/da
Publication of DK142372B publication Critical patent/DK142372B/da
Application granted granted Critical
Publication of DK142372C publication Critical patent/DK142372C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/005—Degradation of the lateral chains at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/863—Mycobacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK323677A 1976-07-16 1977-07-15 Fremgangsmaade til fremstilling af androstan-17-on-derivater DK142372C (da)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DK238478A DK238478A (da) 1976-07-16 1978-05-30 Fremgangsmaade til fremstilling af androstanderivater
DK238378A DK238378A (da) 1976-07-16 1978-05-30 Fremgangsmaade til fremstilling af androstanderivater
DK238278A DK238278A (da) 1976-07-16 1978-05-30 Fremgangsmaade til fremstilling af androstan-17-on-derivater

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2632677 1976-07-16
DE19762632677 DE2632677A1 (de) 1976-07-16 1976-07-16 Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung

Publications (3)

Publication Number Publication Date
DK323677A DK323677A (da) 1978-01-17
DK142372B DK142372B (da) 1980-10-20
DK142372C true DK142372C (da) 1981-03-23

Family

ID=5983514

Family Applications (1)

Application Number Title Priority Date Filing Date
DK323677A DK142372C (da) 1976-07-16 1977-07-15 Fremgangsmaade til fremstilling af androstan-17-on-derivater

Country Status (18)

Country Link
US (1) US4179336A (hu)
JP (1) JPS5315493A (hu)
AT (1) AT363196B (hu)
BE (1) BE856860A (hu)
CH (3) CH627190A5 (hu)
CS (1) CS200517B2 (hu)
DD (4) DD132439A5 (hu)
DE (1) DE2632677A1 (hu)
DK (1) DK142372C (hu)
FR (4) FR2365588A1 (hu)
GB (1) GB1585786A (hu)
HU (4) HU179344B (hu)
IE (1) IE45304B1 (hu)
IT (1) IT1077339B (hu)
NL (1) NL7706638A (hu)
SE (1) SE440779B (hu)
SU (1) SU980628A3 (hu)
YU (1) YU164277A (hu)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55148083A (en) * 1979-05-04 1980-11-18 Mitsubishi Chem Ind Ltd Microorganism
JPS55150893A (en) * 1979-05-11 1980-11-25 Mitsubishi Chem Ind Ltd Novel microorganism
JPS578794A (en) * 1980-06-17 1982-01-18 Mitsubishi Chem Ind Ltd Preparation of androstane-type steroid
US4755463A (en) * 1982-05-25 1988-07-05 Wisconsin Alumni Research Foundation Process for preparing steroids
US4444884A (en) * 1982-05-25 1984-04-24 Wisconsin Alumni Research Foundation Process for preparing steroids
JPH0512528Y2 (hu) * 1987-09-08 1993-03-31
EP0738703B1 (en) * 1995-02-28 2002-05-22 Nippon Shokubai Co., Ltd. Acrylic acid derivatives, method for preparing the acrylic acid derivatives, and acrylic acid polymers
NZ541374A (en) * 2003-05-23 2008-09-26 Nektar Therapeutics Al Corp PEG derivatives having an amidocarbonate linkage
CN102656153B (zh) * 2009-10-29 2015-02-18 延世大学校产学协力团 新型血管渗漏阻断剂
US9388210B2 (en) 2011-02-25 2016-07-12 Washington University Neuroactive 17(20)-Z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same
ES2738526T3 (es) 2011-10-14 2020-01-23 Sage Therapeutics Inc Compuestos 19-norpregnano 3,3-disustituidos, composiciones y usos de los mismos
US9676812B2 (en) 2012-12-18 2017-06-13 Washington University Neuroactive 19-alkoxy-17-substituted steroids, prodrugs thereof, and methods of treatment using same
WO2014127201A1 (en) * 2013-02-15 2014-08-21 Washington University Neuroactive enantiomeric 15-, 16- and 17-substituted steroids as modulators for gaba type-a receptors
US9512170B2 (en) 2013-03-01 2016-12-06 Washington University Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors
US9365502B2 (en) 2013-03-11 2016-06-14 Washington University Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors
US9562026B2 (en) 2013-03-14 2017-02-07 Washington University Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
ES2807264T3 (es) 2013-04-17 2021-02-22 Sage Therapeutics Inc Esteroides neuroactivos 19-nor para métodos de tratamiento
CN108440633B (zh) 2013-04-17 2021-07-13 萨奇治疗股份有限公司 19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
HUE053900T2 (hu) 2013-07-19 2021-07-28 Sage Therapeutics Inc Neuroaktív szteroidok, kompozíciók, és azok alkalmazásai
BR112016003862B1 (pt) 2013-08-23 2022-09-06 Sage Therapeutics, Inc Compostos esteroides neuroativos, suas composições e seus usos
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
EP3206493B1 (en) 2014-10-16 2020-05-06 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
SG10202009859YA (en) 2014-10-16 2020-11-27 Sage Therapeutics Inc Compositions and methods for treating cns disorders
ME03749B (me) 2014-11-27 2021-04-20 Sage Therapeutics Inc KOMPOZICIJE I POSTUPCIZA LEČENJE POREMEĆAJA CNS-a
RS61530B1 (sr) 2015-01-26 2021-04-29 Sage Therapeutics Inc Kompozicije i postupci za lečenje poremećaja cns
WO2016134301A2 (en) 2015-02-20 2016-08-25 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
US20190233465A1 (en) 2016-07-11 2019-08-01 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
DK3481845T3 (da) 2016-07-11 2023-11-27 Sage Therapeutics Inc C17, c20 og c21 substituerede neuroaktive steroider og deres anvendelsesmetoder
JOP20210293A1 (ar) 2019-05-31 2023-01-30 Sage Therapeutics Inc ستيرويدات ذات فعالية عصبية وتركيبات منها

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3451892A (en) * 1965-10-19 1969-06-24 Schering Corp Process for the preparation of steroidal compounds
NL6705450A (hu) * 1965-10-22 1968-10-21
US3684657A (en) * 1970-05-11 1972-08-15 Searle & Co Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione
US3738983A (en) * 1971-08-06 1973-06-12 Searle & Co Process for the preparation of 3-(3beta,17beta-dihydroxyandrost-5-en-17alpha-yl) propionic acid gamma-lactone
DE2534911C2 (de) * 1975-08-01 1985-04-18 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 5-Androsten-17-on-Derivaten

Also Published As

Publication number Publication date
SE7708192L (sv) 1978-01-17
IE45304L (en) 1978-01-16
FR2365588B1 (hu) 1982-06-25
GB1585786A (en) 1981-03-11
NL7706638A (nl) 1978-01-18
SU980628A3 (ru) 1982-12-07
SE440779B (sv) 1985-08-19
HU182790B (en) 1984-03-28
US4179336A (en) 1979-12-18
DD136141A5 (de) 1979-06-20
CH629222A5 (de) 1982-04-15
FR2372175A1 (fr) 1978-06-23
DD137235A5 (de) 1979-08-22
FR2365588A1 (fr) 1978-04-21
JPS6117477B2 (hu) 1986-05-07
HU182789B (en) 1984-03-28
CS200517B2 (en) 1980-09-15
BE856860A (fr) 1978-01-16
FR2372176A1 (fr) 1978-06-23
DE2632677C2 (hu) 1988-06-16
DD132439A5 (de) 1978-09-27
DE2632677A1 (de) 1978-01-26
ATA504677A (de) 1980-12-15
DD136142A5 (de) 1979-06-20
HU182681B (en) 1984-02-28
CH629503A5 (de) 1982-04-30
CH627190A5 (hu) 1981-12-31
JPS5315493A (en) 1978-02-13
HU179344B (en) 1982-10-28
AT363196B (de) 1981-07-10
IT1077339B (it) 1985-05-04
IE45304B1 (en) 1982-07-28
YU164277A (en) 1982-08-31
DK142372B (da) 1980-10-20
DK323677A (da) 1978-01-17
FR2372174A1 (fr) 1978-06-23

Similar Documents

Publication Publication Date Title
DK142372C (da) Fremgangsmaade til fremstilling af androstan-17-on-derivater
DK377A (da) Fremgangsmade til fremstilling af n-phosphonomethyl-glycin
DK244577A (da) Fremgangsmade til fremstilling af hydantoinderivater
DK577977A (da) Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methyler
DK271977A (da) Fremgangsmade til fremstilling af dispeptidderivater
DK339677A (da) Fremgangsmade til fremstilling af 2-benzylpyrrolidiner
DK118177A (da) Fremgangsmade til fremstilling af isobutyramidderivater
DK46577A (da) Fremgangsmade til fremstilling af tetrahydroechinocandinderivater
DK165677A (da) Fremgangsmade til fremstilling af thiourinstofderivater
DK144377A (da) Fremgangsmade til fremstilling af acylcyanider
DK587077A (da) Fremgangsmaade til fremstilling af estere
DK271377A (da) Fremgangsmade til fremstilling af substituerede arylacetamidocephalosporiner
DK144277A (da) Fremgangsmade til fremstilling af acylcyanider
DK216977A (da) Fremgangsmade til fremstilling af imidazobenzoxaziner
DK211277A (da) Fremgangsmade til fremstilling af isothiourinstofderivater
DK264377A (da) Fremgangsmade til fremstilling af 1alfa-hydroxycholesterol-derivater
DK73277A (da) Fremgangsmaade til fremstilling af sulfonylbenzimidazoler
DK538977A (da) Fremgangsmaade til fremstilling af 17alfa-hydroxy-21-acetoxy-progesteron
DK196577A (da) Fremgangsmade til fremstilling af kolecystokinin-pankreozymin-oktapeptidamidsulfatester
DK88277A (da) Fremgangsmade til fremstilling af halogenderivater af 16alfamethylpregnanrekken
DK338677A (da) Frefmgangsmade til fremstilling af 3-alkoxycyproheptadiner
DK106677A (da) Fremgangsmade til fremstilling af 3-nethylencephalosporiner
DK582177A (da) Fremgangsmaade til fremstilling af halogenacylamider
DK97177A (da) Fremgangsmade til fremstilling af cyanoalkylureidocephalosporiner
DK553077A (da) Fremgangsmaade til fremstilling af n-propylnorapomorphindiestere

Legal Events

Date Code Title Description
PBP Patent lapsed