DK1419160T3 - Fremgangsmåde til fremstilling af 6-(4-chlorphenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl-eddikesyre - Google Patents
Fremgangsmåde til fremstilling af 6-(4-chlorphenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl-eddikesyreInfo
- Publication number
- DK1419160T3 DK1419160T3 DK02767415T DK02767415T DK1419160T3 DK 1419160 T3 DK1419160 T3 DK 1419160T3 DK 02767415 T DK02767415 T DK 02767415T DK 02767415 T DK02767415 T DK 02767415T DK 1419160 T3 DK1419160 T3 DK 1419160T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyrrolizin
- chlorophenyl
- dihydro
- dimethyl
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10141285A DE10141285A1 (de) | 2001-08-23 | 2001-08-23 | Verfahren zur Herstellung von 6-(4-Chlorphenyl)-2,2-dimethyl-7-phnyl-2,3-dihydro-1H-pyrrolizin-5-yl-essigsäure |
PCT/EP2002/009356 WO2003018583A1 (de) | 2001-08-23 | 2002-08-21 | Verfahren zur herstellung von 6-(4-chlorphenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizin-5-yl-essigsäure |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1419160T3 true DK1419160T3 (da) | 2009-04-14 |
Family
ID=7696330
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02767415T DK1419160T3 (da) | 2001-08-23 | 2002-08-21 | Fremgangsmåde til fremstilling af 6-(4-chlorphenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl-eddikesyre |
Country Status (32)
Country | Link |
---|---|
US (1) | US7078535B2 (zh) |
EP (1) | EP1419160B1 (zh) |
JP (1) | JP4195379B2 (zh) |
KR (1) | KR100687472B1 (zh) |
CN (1) | CN1266152C (zh) |
AR (1) | AR035117A1 (zh) |
AT (1) | ATE417047T1 (zh) |
AU (1) | AU2002331168C1 (zh) |
BR (1) | BR0212009A (zh) |
CA (1) | CA2458339C (zh) |
CO (1) | CO5560556A2 (zh) |
CU (1) | CU23345A3 (zh) |
CY (1) | CY1109089T1 (zh) |
DE (2) | DE10141285A1 (zh) |
DK (1) | DK1419160T3 (zh) |
EA (1) | EA006436B1 (zh) |
ES (1) | ES2319268T3 (zh) |
GE (1) | GEP20063918B (zh) |
HK (1) | HK1060879A1 (zh) |
HR (1) | HRP20040263B1 (zh) |
HU (1) | HU228125B1 (zh) |
IL (2) | IL160047A0 (zh) |
MX (1) | MXPA04001664A (zh) |
NO (1) | NO328299B1 (zh) |
NZ (1) | NZ531113A (zh) |
PL (1) | PL367796A1 (zh) |
PT (1) | PT1419160E (zh) |
RS (1) | RS51877B (zh) |
TW (1) | TWI274755B (zh) |
UA (1) | UA75702C2 (zh) |
WO (1) | WO2003018583A1 (zh) |
ZA (1) | ZA200402209B (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102005012971A1 (de) * | 2005-03-21 | 2006-09-28 | Merckle Gmbh | Polymorphe Form von 6-(4-Chlorphenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl-essigsäure |
WO2007108006A1 (en) * | 2006-03-23 | 2007-09-27 | Unichem Laboratories Limited | Process for the preparation of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2, 3-dihydro-1h-pyrrolizin-5-yl acetic acid and its intermediates |
CZ2007752A3 (cs) * | 2007-10-30 | 2009-05-13 | Zentiva, A. S. | Nový zpusob výroby 2-(6-(4-chlorfenyl)-2,2-dimethyl-7-fenyl-2,3-dihydro-1H-pyrrolizin-5-yl)octové kyseliny (licofelonu) |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK304185A (da) | 1984-07-27 | 1986-01-28 | Hoffmann La Roche | Fremgangsmaade til fremstilling af furanon |
DE3915450A1 (de) | 1989-05-11 | 1990-11-15 | Gerd Prof Dr Dannhardt | Substituierte pyrrolverbindungen und deren anwendung in der pharmazie |
DE4419247A1 (de) | 1994-06-01 | 1995-12-07 | Merckle Gmbh | Sulfonylierte Pyrrolizincarbonsäureamide und deren Anwendung in der Pharmazie |
DE4419246A1 (de) | 1994-06-01 | 1995-12-07 | Merckle Gmbh | Heteroarylsubstituierte Pyrrolizinverbindungen und deren Anwendung in der Pharmazie |
DE4419315A1 (de) | 1994-06-01 | 1995-12-07 | Merckle Gmbh | Heteropyrrolizinverbindungen und deren Anwendung in der Pharmazie |
SK286608B6 (sk) * | 2000-01-28 | 2009-02-05 | Merckle Gmbh | Spôsob prípravy kyseliny 6-(4-chlórfenyl)-2,2-dimetyl-7-fenyl- 2,3-dihydro-1H-pyrolizin-5-yl octovej |
-
2001
- 2001-08-23 DE DE10141285A patent/DE10141285A1/de not_active Withdrawn
-
2002
- 2002-08-13 AR ARP020103045A patent/AR035117A1/es active IP Right Grant
- 2002-08-21 AU AU2002331168A patent/AU2002331168C1/en not_active Ceased
- 2002-08-21 EP EP02767415A patent/EP1419160B1/de not_active Expired - Lifetime
- 2002-08-21 AT AT02767415T patent/ATE417047T1/de active
- 2002-08-21 MX MXPA04001664A patent/MXPA04001664A/es active IP Right Grant
- 2002-08-21 DK DK02767415T patent/DK1419160T3/da active
- 2002-08-21 WO PCT/EP2002/009356 patent/WO2003018583A1/de active IP Right Grant
- 2002-08-21 HU HU0401440A patent/HU228125B1/hu not_active IP Right Cessation
- 2002-08-21 CN CNB028164490A patent/CN1266152C/zh not_active Expired - Fee Related
- 2002-08-21 PL PL02367796A patent/PL367796A1/xx unknown
- 2002-08-21 PT PT02767415T patent/PT1419160E/pt unknown
- 2002-08-21 UA UA2004032036A patent/UA75702C2/uk unknown
- 2002-08-21 IL IL16004702A patent/IL160047A0/xx unknown
- 2002-08-21 US US10/486,911 patent/US7078535B2/en not_active Expired - Fee Related
- 2002-08-21 JP JP2003523244A patent/JP4195379B2/ja not_active Expired - Fee Related
- 2002-08-21 DE DE50213105T patent/DE50213105D1/de not_active Expired - Lifetime
- 2002-08-21 EA EA200400344A patent/EA006436B1/ru not_active IP Right Cessation
- 2002-08-21 GE GE5474A patent/GEP20063918B/en unknown
- 2002-08-21 RS YU14604A patent/RS51877B/en unknown
- 2002-08-21 CA CA002458339A patent/CA2458339C/en not_active Expired - Fee Related
- 2002-08-21 KR KR1020047002654A patent/KR100687472B1/ko not_active IP Right Cessation
- 2002-08-21 NZ NZ531113A patent/NZ531113A/en not_active IP Right Cessation
- 2002-08-21 ES ES02767415T patent/ES2319268T3/es not_active Expired - Lifetime
- 2002-08-21 BR BR0212009-7A patent/BR0212009A/pt not_active Application Discontinuation
- 2002-08-23 TW TW091119151A patent/TWI274755B/zh not_active IP Right Cessation
-
2004
- 2004-01-26 IL IL160047A patent/IL160047A/en not_active IP Right Cessation
- 2004-01-29 CU CU20040019A patent/CU23345A3/es not_active IP Right Cessation
- 2004-02-19 CO CO04014456A patent/CO5560556A2/es not_active Application Discontinuation
- 2004-03-17 HR HRP20040263AA patent/HRP20040263B1/xx not_active IP Right Cessation
- 2004-03-19 NO NO20041178A patent/NO328299B1/no not_active IP Right Cessation
- 2004-03-19 ZA ZA200402209A patent/ZA200402209B/en unknown
- 2004-05-27 HK HK04103801.9A patent/HK1060879A1/xx not_active IP Right Cessation
-
2009
- 2009-03-06 CY CY20091100258T patent/CY1109089T1/el unknown
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