DK141099B - Fremgangsmåde til rensning af clavulansyre eller et salt deraf med en base. - Google Patents

Fremgangsmåde til rensning af clavulansyre eller et salt deraf med en base. Download PDF

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Publication number
DK141099B
DK141099B DK49876AA DK49876A DK141099B DK 141099 B DK141099 B DK 141099B DK 49876A A DK49876A A DK 49876AA DK 49876 A DK49876 A DK 49876A DK 141099 B DK141099 B DK 141099B
Authority
DK
Denmark
Prior art keywords
salt
lithium
water
clavulanic acid
clavulanate
Prior art date
Application number
DK49876AA
Other languages
Danish (da)
English (en)
Other versions
DK49876A (ja
DK141099C (ja
Inventor
Hazel Mary Noble
David Noble
Ian Dunlop Fleming
Wilfred Frank Wall
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB540975A external-priority patent/GB1543563A/en
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of DK49876A publication Critical patent/DK49876A/da
Priority to DK207378A priority Critical patent/DK146764C/da
Publication of DK141099B publication Critical patent/DK141099B/da
Application granted granted Critical
Publication of DK141099C publication Critical patent/DK141099C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK49876AA 1975-02-07 1976-02-06 Fremgangsmåde til rensning af clavulansyre eller et salt deraf med en base. DK141099B (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK207378A DK146764C (da) 1975-02-07 1978-05-11 Alkalimetalclavulanat til anvendelse som mellemprodukt ved fremstilling af clavulansyre eller andre derivater deraf, samt blanding til anvendelse ved fremstilling af clavulansyre eller derivater deraf

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB540975A GB1543563A (en) 1975-02-07 1975-02-07 Beta-lactam antibiotic in purified form
GB540975 1975-02-07
GB1107675 1975-03-17
GB1107675 1975-03-17

Publications (3)

Publication Number Publication Date
DK49876A DK49876A (ja) 1976-08-08
DK141099B true DK141099B (da) 1980-01-14
DK141099C DK141099C (ja) 1980-07-21

Family

ID=26239868

Family Applications (1)

Application Number Title Priority Date Filing Date
DK49876AA DK141099B (da) 1975-02-07 1976-02-06 Fremgangsmåde til rensning af clavulansyre eller et salt deraf med en base.

Country Status (15)

Country Link
US (3) US4490294A (ja)
JP (2) JPS51101994A (ja)
AT (1) AT353409B (ja)
AU (1) AU509313B2 (ja)
CH (1) CH624956A5 (ja)
DE (1) DE2604697A1 (ja)
DK (1) DK141099B (ja)
ES (1) ES444948A1 (ja)
FI (1) FI63580C (ja)
FR (1) FR2368276A1 (ja)
IE (1) IE43790B1 (ja)
IT (2) IT1059403B (ja)
NL (1) NL7601227A (ja)
SE (1) SE421796B (ja)
YU (1) YU40452B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus
GB1542405A (en) * 1975-04-15 1979-03-21 Beecham Group Ltd Clavulanic acid derivatives
DE2862254D1 (en) * 1977-12-02 1983-06-16 Beecham Group Plc A process for the preparation of ether derivatives of clavulanic acid
DE3063683D1 (en) * 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
GB9702216D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product
GB9702218D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product
EP0867515B1 (en) * 1997-03-24 1999-12-08 CIPAN-Companhia Industrial Produtora De Antibioticos, S.A. Process for the isolation of a pharmaceutically acceptable alkali metal salt of clavulanic acid
JPH11254368A (ja) * 1998-03-12 1999-09-21 Central Motor Co Ltd 部材保持装置
TR200003828T2 (tr) * 1998-07-03 2001-06-21 Dsm N.V. Düşük bir serbest amino asiti konsantrasyonunda klavülanik asitin üretilmesi için fermentasyon işlemi
PT102181A (pt) * 1998-07-20 2000-01-31 Dsm Nv Processo melhorado para a producao de acido clavulanico
IL155194A0 (en) * 2000-10-05 2003-11-23 Biogal Pharmaceutical Co Ltd Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
US20040072815A1 (en) * 2002-02-12 2004-04-15 Koppel Gary A. Antibiotic composition and method
KR100461278B1 (ko) * 2002-10-23 2004-12-10 현대자동차주식회사 용접 대상물의 위치규제 및 취출장치
KR20200060482A (ko) 2017-10-02 2020-05-29 메타볼릭 익스플로러 발효액에서 유기산 염을 생산하기 위한 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754693A (fr) * 1969-08-12 1971-02-11 Lilly Co Eli Nouvel antibiotique et procede pour le preparer
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus
JO984B1 (en) * 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration

Also Published As

Publication number Publication date
SE7601337L (sv) 1976-11-03
YU40452B (en) 1986-02-28
NL7601227A (nl) 1976-08-10
AT353409B (de) 1979-11-12
SE421796B (sv) 1982-02-01
DE2604697A1 (de) 1976-08-19
IE43790B1 (en) 1981-06-03
DE2604697C2 (ja) 1992-10-29
US4490295A (en) 1984-12-25
US4490294A (en) 1984-12-25
DK49876A (ja) 1976-08-08
FR2368276A1 (fr) 1978-05-19
IE43790L (en) 1976-08-07
FR2368276B1 (ja) 1979-03-16
IT1059403B (it) 1982-05-31
JPH0222281A (ja) 1990-01-25
IT1066098B (it) 1985-03-04
YU29076A (en) 1982-08-31
JPS51101994A (ja) 1976-09-08
DK141099C (ja) 1980-07-21
AU1089176A (en) 1977-08-11
ATA83476A (de) 1979-04-15
ES444948A1 (es) 1977-08-16
FI63580B (fi) 1983-03-31
US4367175A (en) 1983-01-04
FI760285A (ja) 1976-08-08
AU509313B2 (en) 1980-05-08
FI63580C (fi) 1983-07-11
CH624956A5 (de) 1981-08-31

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