DK141095B - Analogifremgangsmåde til fremstilling af tetracycliske piperidinderivater eller et syreadditionssalt eller kvaternært ammoniumsalt deraf. - Google Patents

Analogifremgangsmåde til fremstilling af tetracycliske piperidinderivater eller et syreadditionssalt eller kvaternært ammoniumsalt deraf. Download PDF

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Publication number
DK141095B
DK141095B DK32275AA DK32275A DK141095B DK 141095 B DK141095 B DK 141095B DK 32275A A DK32275A A DK 32275AA DK 32275 A DK32275 A DK 32275A DK 141095 B DK141095 B DK 141095B
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DK
Denmark
Prior art keywords
pyridine
acid
methyl
alkyl
acid addition
Prior art date
Application number
DK32275AA
Other languages
Danish (da)
English (en)
Other versions
DK141095C (es
DK32275A (es
Inventor
Willem Jacob Van Der Burg
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK32275A publication Critical patent/DK32275A/da
Publication of DK141095B publication Critical patent/DK141095B/da
Application granted granted Critical
Publication of DK141095C publication Critical patent/DK141095C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK32275AA 1974-01-31 1975-01-30 Analogifremgangsmåde til fremstilling af tetracycliske piperidinderivater eller et syreadditionssalt eller kvaternært ammoniumsalt deraf. DK141095B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NLAANVRAGE7401324,A NL178593C (nl) 1974-01-31 1974-01-31 Werkwijze ter bereiding van een farmaceutisch preparaat op basis van een tetracyclische verbinding en werkwijze voor de bereiding van de daarbij te gebruiken tetracyclische verbindingen.
NL7401324 1974-01-31

Publications (3)

Publication Number Publication Date
DK32275A DK32275A (es) 1975-09-29
DK141095B true DK141095B (da) 1980-01-14
DK141095C DK141095C (es) 1980-06-30

Family

ID=19820652

Family Applications (1)

Application Number Title Priority Date Filing Date
DK32275AA DK141095B (da) 1974-01-31 1975-01-30 Analogifremgangsmåde til fremstilling af tetracycliske piperidinderivater eller et syreadditionssalt eller kvaternært ammoniumsalt deraf.

Country Status (16)

Country Link
US (1) US4002632A (es)
JP (1) JPS5939427B2 (es)
BE (1) BE825018A (es)
CA (1) CA1053671A (es)
CH (3) CH618162A5 (es)
DE (1) DE2503407A1 (es)
DK (1) DK141095B (es)
ES (3) ES434242A1 (es)
FI (1) FI60563C (es)
FR (1) FR2272676B1 (es)
GB (1) GB1500042A (es)
HU (1) HU169160B (es)
IE (1) IE40661B1 (es)
NL (1) NL178593C (es)
SE (1) SE418615B (es)
ZA (1) ZA75417B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH624105A5 (en) * 1976-05-26 1981-07-15 Ciba Geigy Ag Process for the preparation of novel azatetracyclic compounds
US4271179A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 1,2,3,3a,8,12b-Hexahydro-dibenzo[1,2;5,6]cyclohepta[3,4-C]pyrroles and pharmaceutical use thereof
US4158059A (en) * 1976-05-24 1979-06-12 Akzona Incorporated Tension reducing 2,3,4,4a,9,136-hexahydro-dibenz[1,2;5,6]cyclohepta[3,4-c]py
US4177275A (en) * 1976-05-24 1979-12-04 Akzona Inc. Tension reducing 2,3,4,4a,9,13b-hexahydro-1H-dibenzo[b,f]pyrido[3,4-d]azepine derivatives
US4271177A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 2,3,3a,12b-Tetrahydro-1H-dibenzo[2,3;6,7]thiepino[4,5-c]pyrroles and pharmaceutical use thereof
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.
US4263438A (en) * 1977-09-13 1981-04-21 Pfizer Inc. 3-[2,4-(Disubstituted)-phenyl]azacycloalkanones as analgesics
US4387229A (en) * 1977-09-13 1983-06-07 Pfizer Inc. 3-[2-Hydroxy-4-(substituted)phenyl]azacycloalkanols and derivatives thereof
US4707476A (en) * 1978-11-17 1987-11-17 Ciba-Geigy Corporation Treating states of agitation with azatetracyclic compounds
JPS5665825A (en) * 1979-10-31 1981-06-03 Mochida Pharmaceut Co Ltd Remedy for peptic ulcer
EP0030916B1 (de) * 1979-12-10 1984-08-29 Ciba-Geigy Ag Azatetracyclische Carbonitrile
AU2418499A (en) * 1997-12-19 1999-07-12 Akzo Nobel N.V. Org-5222 in the treatment of depression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR92375E (fr) * 1966-02-04 1968-10-31 Rhone Poulenc Sa Nouveaux dérivés du dibenzocycloheptatriène et leur préparation
NL7202963A (es) * 1972-03-07 1973-09-11

Also Published As

Publication number Publication date
ES452601A1 (es) 1977-09-01
IE40661L (en) 1975-07-31
DE2503407A1 (de) 1975-08-07
JPS5939427B2 (ja) 1984-09-22
ZA75417B (en) 1976-01-28
FR2272676A1 (es) 1975-12-26
FI750233A (es) 1975-08-01
FI60563B (fi) 1981-10-30
US4002632A (en) 1977-01-11
ES434242A1 (es) 1977-04-01
IE40661B1 (en) 1979-07-18
HU169160B (es) 1976-10-28
GB1500042A (en) 1978-02-08
FI60563C (fi) 1982-02-10
CH618684A5 (es) 1980-08-15
SE418615B (sv) 1981-06-15
BE825018A (fr) 1975-07-30
CH618162A5 (es) 1980-07-15
DK141095C (es) 1980-06-30
NL178593C (nl) 1986-04-16
ES452602A1 (es) 1977-09-16
JPS50106968A (es) 1975-08-22
FR2272676B1 (es) 1980-01-04
DE2503407C2 (es) 1987-07-09
CA1053671A (en) 1979-05-01
AU7755875A (en) 1976-07-29
CH618685A5 (es) 1980-08-15
SE7501002L (es) 1975-08-01
DK32275A (es) 1975-09-29
NL7401324A (nl) 1975-08-04

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