DK139969B - Analogifremgangsmåde til fremstilling af 1-alkylcarbamoyl-5-fluoruraciler. - Google Patents

Analogifremgangsmåde til fremstilling af 1-alkylcarbamoyl-5-fluoruraciler.

Info

Publication number
DK139969B
DK139969B DK498676AA DK498676A DK139969B DK 139969 B DK139969 B DK 139969B DK 498676A A DK498676A A DK 498676AA DK 498676 A DK498676 A DK 498676A DK 139969 B DK139969 B DK 139969B
Authority
DK
Denmark
Prior art keywords
fluorouracils
alkylcarbamoyl
preparation
analogous process
analogous
Prior art date
Application number
DK498676AA
Other languages
Danish (da)
English (en)
Other versions
DK498676A (de
DK139969C (de
Inventor
Shoichiro Ozaki
Haruki Mori
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of DK498676A publication Critical patent/DK498676A/da
Publication of DK139969B publication Critical patent/DK139969B/da
Application granted granted Critical
Publication of DK139969C publication Critical patent/DK139969C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK498676AA 1975-11-05 1976-11-04 Analogifremgangsmåde til fremstilling af 1-alkylcarbamoyl-5-fluoruraciler. DK139969B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/628,974 US4071519A (en) 1975-11-05 1975-11-05 1-Carbamoyl-5-fluorouracil derivatives

Publications (3)

Publication Number Publication Date
DK498676A DK498676A (de) 1977-05-06
DK139969B true DK139969B (da) 1979-05-28
DK139969C DK139969C (de) 1979-11-05

Family

ID=24521080

Family Applications (1)

Application Number Title Priority Date Filing Date
DK498676AA DK139969B (da) 1975-11-05 1976-11-04 Analogifremgangsmåde til fremstilling af 1-alkylcarbamoyl-5-fluoruraciler.

Country Status (10)

Country Link
US (1) US4071519A (de)
JP (1) JPS5277073A (de)
BE (1) BE846956A (de)
DE (1) DE2639135C2 (de)
DK (1) DK139969B (de)
FI (1) FI61886C (de)
FR (1) FR2330401A1 (de)
GB (1) GB1524640A (de)
NL (1) NL184469C (de)
SE (1) SE422205B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68935B (de) * 1976-03-31 1982-03-29 Takeda Chemical Industries Ltd
JPS5446791A (en) * 1977-09-22 1979-04-12 Takeda Chem Ind Ltd Fluorouracil derivative
US4349552A (en) * 1978-10-30 1982-09-14 Fujisawa Pharmaceutical Company, Ltd. 5-Fluorouracil derivatives, and their pharmaceutical compositions
JPS5785374A (en) * 1980-11-18 1982-05-28 Mitsui Toatsu Chem Inc 5-fluorouracil derivative and its preparation
JPS61204172A (ja) * 1985-03-07 1986-09-10 Nippon Kayaku Co Ltd 5−フルオロウラシル誘導体
DE3781357T2 (de) * 1986-10-09 1993-03-18 Daikin Ind Ltd 5-fluorouracil-derivate, pharmazeutische zubereitung und verwendung.
JPH0273723U (de) * 1988-11-26 1990-06-05
WO2009042064A2 (en) 2007-09-21 2009-04-02 Nektar Therapeutics Al, Corporation Oligomer-nucleoside phosphate conjugates
CA2790707A1 (en) * 2010-03-01 2011-09-09 Concert Pharmaceuticals Inc. Fluorouracil derivatives
WO2017123823A1 (en) * 2016-01-12 2017-07-20 Bioelectron Technology Corporation Alkyl-, acyl-, urea-, and aza-uracil sulfide:quinone oxidoreductase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5324952B2 (de) * 1973-11-28 1978-07-24

Also Published As

Publication number Publication date
DE2639135C2 (de) 1983-04-14
JPS5277073A (en) 1977-06-29
US4071519A (en) 1978-01-31
GB1524640A (en) 1978-09-13
SE422205B (sv) 1982-02-22
FI61886C (fi) 1982-10-11
JPS5549578B2 (de) 1980-12-12
FI61886B (fi) 1982-06-30
NL184469B (nl) 1989-03-01
FR2330401A1 (fr) 1977-06-03
FR2330401B1 (de) 1980-04-18
BE846956A (fr) 1977-01-31
NL184469C (nl) 1989-08-01
DK498676A (de) 1977-05-06
SE7607088L (sv) 1977-05-06
DE2639135A1 (de) 1977-05-18
DK139969C (de) 1979-11-05
NL7608892A (nl) 1977-05-09

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Legal Events

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PUP Patent expired