NL7608892A - 1-carbamoyl-5-fluoruracilderivaten. - Google Patents

1-carbamoyl-5-fluoruracilderivaten.

Info

Publication number
NL7608892A
NL7608892A NL7608892A NL7608892A NL7608892A NL 7608892 A NL7608892 A NL 7608892A NL 7608892 A NL7608892 A NL 7608892A NL 7608892 A NL7608892 A NL 7608892A NL 7608892 A NL7608892 A NL 7608892A
Authority
NL
Netherlands
Prior art keywords
divatives
fluoruracil
carbamoyl
fluoruracil divatives
Prior art date
Application number
NL7608892A
Other languages
English (en)
Other versions
NL184469B (nl
NL184469C (nl
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of NL7608892A publication Critical patent/NL7608892A/nl
Publication of NL184469B publication Critical patent/NL184469B/nl
Application granted granted Critical
Publication of NL184469C publication Critical patent/NL184469C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NLAANVRAGE7608892,A 1975-11-05 1976-08-10 Werkwijze voor het bereiden van een geneesmiddel met antitumorwerking op basis van een 1-alkylcarbamoyl-5-uracilderivaat alsmede werkwijze voor het bereiden van hierbij te gebruiken geneeskrachtige 1-alkylcarbamoyl-5-fluoruracilderivaten. NL184469C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/628,974 US4071519A (en) 1975-11-05 1975-11-05 1-Carbamoyl-5-fluorouracil derivatives

Publications (3)

Publication Number Publication Date
NL7608892A true NL7608892A (nl) 1977-05-09
NL184469B NL184469B (nl) 1989-03-01
NL184469C NL184469C (nl) 1989-08-01

Family

ID=24521080

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7608892,A NL184469C (nl) 1975-11-05 1976-08-10 Werkwijze voor het bereiden van een geneesmiddel met antitumorwerking op basis van een 1-alkylcarbamoyl-5-uracilderivaat alsmede werkwijze voor het bereiden van hierbij te gebruiken geneeskrachtige 1-alkylcarbamoyl-5-fluoruracilderivaten.

Country Status (10)

Country Link
US (1) US4071519A (nl)
JP (1) JPS5277073A (nl)
BE (1) BE846956A (nl)
DE (1) DE2639135C2 (nl)
DK (1) DK139969B (nl)
FI (1) FI61886C (nl)
FR (1) FR2330401A1 (nl)
GB (1) GB1524640A (nl)
NL (1) NL184469C (nl)
SE (1) SE422205B (nl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68935B (nl) * 1976-03-31 1982-03-29 Takeda Chemical Industries Ltd
JPS5446791A (en) * 1977-09-22 1979-04-12 Takeda Chem Ind Ltd Fluorouracil derivative
US4349552A (en) * 1978-10-30 1982-09-14 Fujisawa Pharmaceutical Company, Ltd. 5-Fluorouracil derivatives, and their pharmaceutical compositions
JPS5785374A (en) * 1980-11-18 1982-05-28 Mitsui Toatsu Chem Inc 5-fluorouracil derivative and its preparation
JPS61204172A (ja) * 1985-03-07 1986-09-10 Nippon Kayaku Co Ltd ５−フルオロウラシル誘導体
DE3781357T2 (de) * 1986-10-09 1993-03-18 Daikin Ind Ltd 5-fluorouracil-derivate, pharmazeutische zubereitung und verwendung.
JPH0273723U (nl) * 1988-11-26 1990-06-05
WO2009042064A2 (en) 2007-09-21 2009-04-02 Nektar Therapeutics Al, Corporation Oligomer-nucleoside phosphate conjugates
EP2542075A4 (en) * 2010-03-01 2014-11-05 Concert Pharmaceuticals Inc Fluorouracil DERIVATIVES
WO2017123823A1 (en) * 2016-01-12 2017-07-20 Bioelectron Technology Corporation Alkyl-, acyl-, urea-, and aza-uracil sulfide:quinone oxidoreductase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5324952B2 (nl) * 1973-11-28 1978-07-24

Also Published As

Publication number Publication date
NL184469B (nl) 1989-03-01
FR2330401B1 (nl) 1980-04-18
DK139969C (nl) 1979-11-05
BE846956A (fr) 1977-01-31
FR2330401A1 (fr) 1977-06-03
JPS5277073A (en) 1977-06-29
SE7607088L (sv) 1977-05-06
DE2639135A1 (de) 1977-05-18
SE422205B (sv) 1982-02-22
JPS5549578B2 (nl) 1980-12-12
DK498676A (nl) 1977-05-06
US4071519A (en) 1978-01-31
GB1524640A (en) 1978-09-13
NL184469C (nl) 1989-08-01
FI61886C (fi) 1982-10-11
DE2639135C2 (de) 1983-04-14
FI61886B (fi) 1982-06-30
DK139969B (da) 1979-05-28

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee