DK1392314T3 - Hidtil ukendt anvendelse af 2-[2-ethoxy-5-(4-methyl-piperazin-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-on - Google Patents

Hidtil ukendt anvendelse af 2-[2-ethoxy-5-(4-methyl-piperazin-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-on

Info

Publication number
DK1392314T3
DK1392314T3 DK02740570T DK02740570T DK1392314T3 DK 1392314 T3 DK1392314 T3 DK 1392314T3 DK 02740570 T DK02740570 T DK 02740570T DK 02740570 T DK02740570 T DK 02740570T DK 1392314 T3 DK1392314 T3 DK 1392314T3
Authority
DK
Denmark
Prior art keywords
methyl
phenyl
triazin
imidazo
piperazine
Prior art date
Application number
DK02740570T
Other languages
Danish (da)
English (en)
Inventor
Wolfgang Barth
Der Staay Franz-Josef Van
Ulrich Niewoehner
Erwin Bischoff
Helmut Haning
Afssaneh Rahbar
Tiemo-Joerg Bandel
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10126198A external-priority patent/DE10126198A1/de
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Application granted granted Critical
Publication of DK1392314T3 publication Critical patent/DK1392314T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK02740570T 2001-05-09 2002-05-07 Hidtil ukendt anvendelse af 2-[2-ethoxy-5-(4-methyl-piperazin-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-on DK1392314T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10122576 2001-05-09
DE10126198A DE10126198A1 (de) 2001-05-09 2001-05-30 Neue Verwendung von 2-Phenyl-substituierten Imidazotriazinonen
PCT/EP2002/005002 WO2002089808A1 (de) 2001-05-09 2002-05-07 Neue verwendung von 2-phenyl-substituierten imidazotriazinonen

Publications (1)

Publication Number Publication Date
DK1392314T3 true DK1392314T3 (da) 2007-03-12

Family

ID=26009261

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02740570T DK1392314T3 (da) 2001-05-09 2002-05-07 Hidtil ukendt anvendelse af 2-[2-ethoxy-5-(4-methyl-piperazin-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-on

Country Status (15)

Country Link
US (1) US20040152700A1 (zh)
EP (1) EP1392314B1 (zh)
JP (1) JP4540295B2 (zh)
CN (1) CN1633298A (zh)
AT (1) ATE348618T1 (zh)
AU (1) AU2002314044B2 (zh)
BR (1) BR0209541A (zh)
CA (1) CA2449163C (zh)
DE (1) DE50209015D1 (zh)
DK (1) DK1392314T3 (zh)
ES (1) ES2278927T3 (zh)
IL (1) IL158738A0 (zh)
MX (1) MXPA03010119A (zh)
PL (1) PL363679A1 (zh)
WO (1) WO2002089808A1 (zh)

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DE10232113A1 (de) * 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
ATE445402T1 (de) * 2004-03-05 2009-10-15 Nycomed Gmbh Neue verwendung von pde5-hemmern
DE102004023069A1 (de) 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
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DE102005001989A1 (de) * 2005-01-15 2006-07-20 Bayer Healthcare Ag Intravenöse Formulierungen von PDE-Inhibitoren
DE102005009240A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
DE102005009241A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
JP2009509984A (ja) * 2005-09-29 2009-03-12 バイエル・ヘルスケア・アクチェンゲゼルシャフト 泌尿器系障害の処置用のｐｄｅ阻害剤およびそれらの組合せ
US8841300B2 (en) 2006-10-02 2014-09-23 Jerry M. Held Treatment for Parkinson's disease—combination high dose serotonergic synaptic reuptake inhibitor with phosphodiesterase inhibitor
JP2010527928A (ja) 2007-05-18 2010-08-19 ヴィヴァス・インコーポレイテッド ホスホジエステラーゼ−５阻害剤を含む新規の組み合わせおよびそれらの使用
JP2010532319A (ja) * 2007-06-13 2010-10-07 バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト 聴覚障害の処置用のｐｄｅ阻害剤
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EP2929886B1 (en) * 2012-12-04 2021-11-24 Aribio Inc. Composition comprising phosphodiesterase type 5 inhibitor for inhibiting apoptosis of nerve cells
JP2022509815A (ja) 2018-11-28 2022-01-24 トパデュール ファルマ アーゲー 新規の二重作用型可溶性グアニル酸シクラーゼ活性化剤およびホスホジエステラーゼ阻害剤とその使用法
CN113493459B (zh) * 2020-04-07 2022-12-13 广州白云山医药集团股份有限公司白云山制药总厂 Pde5抑制剂化合物及其制备方法和应用

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Also Published As

Publication number Publication date
IL158738A0 (en) 2004-05-12
ATE348618T1 (de) 2007-01-15
CA2449163C (en) 2010-07-13
PL363679A1 (en) 2004-11-29
WO2002089808A1 (de) 2002-11-14
EP1392314A1 (de) 2004-03-03
MXPA03010119A (es) 2005-03-07
DE50209015D1 (de) 2007-02-01
ES2278927T3 (es) 2007-08-16
JP4540295B2 (ja) 2010-09-08
EP1392314B1 (de) 2006-12-20
CA2449163A1 (en) 2002-11-14
JP2004528363A (ja) 2004-09-16
AU2002314044B2 (en) 2006-09-21
US20040152700A1 (en) 2004-08-05
BR0209541A (pt) 2004-04-20
CN1633298A (zh) 2005-06-29

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