DK138598B - Analogifremgangsmåde til fremstilling af farmakodynamisk aktive, basisk substituerede indanderivater. - Google Patents

Analogifremgangsmåde til fremstilling af farmakodynamisk aktive, basisk substituerede indanderivater.

Info

Publication number
DK138598B
DK138598B DK156173AA DK156173A DK138598B DK 138598 B DK138598 B DK 138598B DK 156173A A DK156173A A DK 156173AA DK 156173 A DK156173 A DK 156173A DK 138598 B DK138598 B DK 138598B
Authority
DK
Denmark
Prior art keywords
preparation
analogous process
indane derivatives
basic substituted
pharmacodynamically active
Prior art date
Application number
DK156173AA
Other languages
Danish (da)
English (en)
Other versions
DK138598C (pt
Inventor
Barbro Ka Goeransson-Dahlander
Nils Aake Joensson
Ferenc Merenyi
Original Assignee
Kabi Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Ab filed Critical Kabi Ab
Publication of DK138598B publication Critical patent/DK138598B/da
Application granted granted Critical
Publication of DK138598C publication Critical patent/DK138598C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/665Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
    • C07C49/675Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having three rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/62Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
DK156173AA 1972-03-24 1973-03-22 Analogifremgangsmåde til fremstilling af farmakodynamisk aktive, basisk substituerede indanderivater. DK138598B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7203905A SE371190B (pt) 1972-03-24 1972-03-24

Publications (2)

Publication Number Publication Date
DK138598B true DK138598B (da) 1978-10-02
DK138598C DK138598C (pt) 1979-03-26

Family

ID=20263107

Family Applications (1)

Application Number Title Priority Date Filing Date
DK156173AA DK138598B (da) 1972-03-24 1973-03-22 Analogifremgangsmåde til fremstilling af farmakodynamisk aktive, basisk substituerede indanderivater.

Country Status (12)

Country Link
US (1) US4172093A (pt)
JP (1) JPS599540B2 (pt)
AT (1) AT329045B (pt)
CA (1) CA1032165A (pt)
CH (4) CH621110A5 (pt)
DE (1) DE2314636C2 (pt)
DK (1) DK138598B (pt)
FI (1) FI57253C (pt)
FR (1) FR2177929B1 (pt)
GB (1) GB1421208A (pt)
NO (1) NO138628C (pt)
SE (1) SE371190B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2861735D1 (en) * 1977-08-05 1982-05-27 Kabi Ab Geminally disubstituted indene derivatives, processes for their preparation and pharmaceutical compositions containing them
CH641147A5 (de) * 1979-01-17 1984-02-15 Sandoz Ag 3-amino-2-hydroxypropoxyaryl-derivat, seine herstellung und dieses enthaltende heilmittel.
CH647235A5 (de) * 1980-02-13 1985-01-15 Sandoz Ag 4-(2,2-dialkylindan-1-yliden)piperidin derivate, ihre herstellung und verwendung.
IL103106A (en) * 1991-09-25 1998-06-15 Sanofi Elf Sites of tynocyclopentanone oximes, their preparation and pharmaceutical preparations containing them
GB9309621D0 (en) * 1993-05-11 1993-06-23 Wellcome Found Amide derivatives and their therapeutic use
US5877218A (en) * 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
MY113062A (en) * 1994-05-10 2001-11-30 The Wellcome Foundation Ltd Amide derivatives and their therapeutic use
DE69732984T2 (de) 1996-12-18 2006-02-16 Teva Pharmaceutical Industries Ltd. Aminoindanderivate
US6124284A (en) * 1998-07-16 2000-09-26 Glaxo Wellcome Inc. Bicyclic amide derivatives and their use as muscle relaxants
US6737547B1 (en) 1998-12-31 2004-05-18 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using N-acyl-1H-aminoindenes
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
GB0328906D0 (en) 2003-12-12 2004-01-14 Syngenta Participations Ag Chemical compounds
US20070135518A1 (en) * 2005-12-09 2007-06-14 Marta Weinstock-Rosin Use of low-dose ladostigil for neuroprotection
BRPI0620659A2 (pt) * 2005-12-09 2017-10-31 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd método para a prevenção do aparecimento de sintomas de uma doença neurodegenerativa em um indivíduo predisposto à doença neurodegenerativa, método de redução de stress oxidante no cérebro de um indivíduo afligido com stress oxidante, método de tratamento de um indivíduo afligido com a degeneração cognitiva suave e composição farmacêutica
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1007323B (de) * 1956-04-13 1957-05-02 Schering Ag Verfahren zur Herstellung von 1-Aminoindanen mit coronargefaesserweiternder Wirkung
US3308157A (en) * 1964-08-07 1967-03-07 Colgate Palmolive Co N-(benzocyclobutene-1-loweralkyl)-carboxylic acid amides
US3360435A (en) * 1964-09-15 1967-12-26 Mead Johnson & Co Treatment of depressed states
US3553093A (en) * 1965-03-19 1971-01-05 Xerox Corp Color photoelectrophoretic imaging process
GB1139135A (en) * 1965-10-01 1969-01-08 Kefalas As Aminoalkyl-substituted indanes and pharmaceutical compositions containing them
US3657440A (en) * 1968-04-23 1972-04-18 Ciba Geigy Corp Aminoalkyl-spirocycloalkanes as analgetic agents
CH554310A (de) * 1968-04-23 1974-09-30 Ciba Geigy Ag Verfahren zur herstellung von neuen 1-aminoalkylidenbenzcycloalkan-2-spirocycloaliphatischen verbindungen.

Also Published As

Publication number Publication date
DE2314636C2 (de) 1986-09-11
CH622769A5 (pt) 1981-04-30
FR2177929A1 (pt) 1973-11-09
GB1421208A (en) 1976-01-14
CH621110A5 (pt) 1981-01-15
CH626045A5 (pt) 1981-10-30
JPS495957A (pt) 1974-01-19
FR2177929B1 (pt) 1976-10-22
NO138628C (no) 1978-10-11
CH626044A5 (pt) 1981-10-30
DK138598C (pt) 1979-03-26
US4172093A (en) 1979-10-23
FI57253C (fi) 1980-07-10
NO138628B (no) 1978-07-03
DE2314636A1 (de) 1973-10-04
AT329045B (de) 1976-04-26
SE371190B (pt) 1974-11-11
FI57253B (fi) 1980-03-31
ATA255373A (de) 1975-07-15
CA1032165A (en) 1978-05-30
JPS599540B2 (ja) 1984-03-03
AU5365173A (en) 1974-09-26

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