DK135775B - Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner. - Google Patents

Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner.

Info

Publication number
DK135775B
DK135775B DK260473AA DK260473A DK135775B DK 135775 B DK135775 B DK 135775B DK 260473A A DK260473A A DK 260473AA DK 260473 A DK260473 A DK 260473A DK 135775 B DK135775 B DK 135775B
Authority
DK
Denmark
Prior art keywords
pregnanes
3alpha
5alpha
hydroxy
saturated
Prior art date
Application number
DK260473AA
Other languages
English (en)
Other versions
DK135775C (da
Inventor
Gordon Hanley Phillipps
Robin Lawrence
Leslie Stephenson
Barry Edward Ayres
Original Assignee
Glazo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glazo Lab Ltd filed Critical Glazo Lab Ltd
Publication of DK135775B publication Critical patent/DK135775B/da
Application granted granted Critical
Publication of DK135775C publication Critical patent/DK135775C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK260473AA 1972-05-12 1973-05-11 Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner. DK135775B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2248972A GB1436324A (en) 1972-05-12 1972-05-12 Anaesthetic 3alpha-hydroxy pregnanes

Publications (2)

Publication Number Publication Date
DK135775B true DK135775B (da) 1977-06-20
DK135775C DK135775C (da) 1977-11-21

Family

ID=10180241

Family Applications (1)

Application Number Title Priority Date Filing Date
DK260473AA DK135775B (da) 1972-05-12 1973-05-11 Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner.

Country Status (13)

Country Link
US (1) US3998829A (da)
JP (1) JPS4948652A (da)
AU (1) AU474687B2 (da)
BE (1) BE799433A (da)
CA (1) CA1014947A (da)
DE (1) DE2323950A1 (da)
DK (1) DK135775B (da)
FR (1) FR2184711B1 (da)
GB (1) GB1436324A (da)
IE (1) IE38863B1 (da)
LU (1) LU67585A1 (da)
NL (1) NL7306606A (da)
ZA (1) ZA733218B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613463A (en) * 1984-11-01 1986-09-23 The Upjohn Company Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
US5506354A (en) * 1985-09-12 1996-04-09 The Upjohn Company Imidazolylpiperazinyl steroids
USRE35053E (en) * 1985-09-12 1995-10-10 The Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
JPH072555Y2 (ja) * 1991-06-03 1995-01-25 日野自動車工業株式会社 車輛の前後方向兼用ウインチ
WO1996040043A2 (en) * 1995-06-06 1996-12-19 Cocensys, Inc. Neuroactive steroids of the androstane and pregnane series
US6780853B1 (en) 1995-06-06 2004-08-24 Euro-Celtique S.A. Neuroactive steroids of the androstane and pregnane series
US6143737A (en) * 1995-06-23 2000-11-07 Georgetown University Progesterone analogs to reverse multidrug resistance
UA73736C2 (en) * 1999-04-29 2005-09-15 Euro Celtic S A Method for alleviating or preventing insomnia and inducing anesthesia
US20050101581A1 (en) * 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
ES2738526T3 (es) 2011-10-14 2020-01-23 Sage Therapeutics Inc Compuestos 19-norpregnano 3,3-disustituidos, composiciones y usos de los mismos
CA2909546C (en) 2013-04-17 2019-01-22 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
SG11201508550XA (en) 2013-04-17 2015-11-27 Sage Therapeutics Inc 19-nor c3,3-disubstituted c21-n-pyrazolyl steroids and methods of use thereof
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
SI3021852T1 (sl) 2013-07-19 2021-07-30 Sage Therapeutics, Inc. Nevroaktivni steroidi, sestavki in uporabe le-teh
EP3035940B1 (en) 2013-08-23 2018-10-17 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
PL3206493T3 (pl) 2014-10-16 2021-01-25 Sage Therapeutics, Inc. Kompozycje i sposoby leczenia zaburzeń OUN
SG10202009861SA (en) 2014-10-16 2020-11-27 Sage Therapeutics Inc Compositions and methods for treating cns disorders
LT3224269T (lt) * 2014-11-27 2020-07-10 Sage Therapeutics, Inc. Kompozicijos ir būdai, skirti cns sutrikimams gydyti
PL3250210T3 (pl) 2015-01-26 2021-07-26 Sage Therapeutics, Inc. Kompozycje i sposoby leczenia zaburzeń OUN
DK3258939T3 (da) 2015-02-20 2022-12-12 Sage Therapeutics Inc Neuroaktive steroider, sammensætninger og anvendelser heraf
CN116162121A (zh) 2016-07-11 2023-05-26 萨奇治疗股份有限公司 C17、c20和c21取代的神经活性类固醇及其使用方法
US20190233465A1 (en) 2016-07-11 2019-08-01 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
MX2021014515A (es) 2019-05-31 2022-03-22 Sage Therapeutics Inc Esteroides neuroactivos y composiciones de estos.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1107662B (de) * 1959-07-04 1961-05-31 Merck Ag E Verfahren zur Herstellung von Mannichbasen von Steroiden bzw. von deren Saeureadditionssalzen
US3042691A (en) * 1960-05-11 1962-07-03 Pfizer & Co C 5alpha,21-dibromo-6beta-fluoro-21-methyl-pregnanes and process for making same
FR1764M (fr) * 1962-02-20 1963-04-08 Roussel Uclaf Nouveau médicament notamment pour le traitement des spasmes d'origine coronarienne ou viscérale.
US3201425A (en) * 1963-12-10 1965-08-17 American Cyanamid Co 20-alkoxy-delta20-21-carboxaldehydes of the pregnane series and method of preparing the same
GB1089945A (en) * 1965-09-23 1967-11-08 British Drug Houses Ltd Steroidal-6-spirocyclopropyl-4-en-3-ones
GB1317184A (en) * 1969-06-20 1973-05-16 Glaxo Lab Ltd Steroid-containing pharmaceutical preparations
DE1941226A1 (de) * 1969-08-13 1971-02-18 Degussa Basisch substituierte Ketosteroide
US3661940A (en) * 1970-04-13 1972-05-09 Sandoz Ag Derivatives of 21-methyl-19-norpregnanes
GB1377609A (en) * 1970-12-17 1974-12-18 Glaxo Lab Ltd 3alpha-hydroxy-5alpha-pregnane compounds
GB1416427A (en) * 1972-01-12 1975-12-03 Akzo Nv Alkylated pregnanes and process for obtaining same

Also Published As

Publication number Publication date
DE2323950A1 (de) 1973-12-13
BE799433A (fr) 1973-11-12
AU5561673A (en) 1974-11-14
IE38863L (en) 1973-11-12
FR2184711B1 (da) 1977-01-07
CA1014947A (en) 1977-08-02
DK135775C (da) 1977-11-21
ZA733218B (en) 1974-05-29
AU474687B2 (en) 1976-07-29
FR2184711A1 (da) 1973-12-28
US3998829A (en) 1976-12-21
IE38863B1 (en) 1978-06-21
LU67585A1 (da) 1973-07-24
GB1436324A (en) 1976-05-19
NL7306606A (da) 1973-11-14
JPS4948652A (da) 1974-05-11

Similar Documents

Publication Publication Date Title
DK134607B (da) Fremgangsmåde til fremstilling af rapamycin.
DK138951B (da) Fremgangsmåde til fremstilling af N-phosphonomethyl-glycin.
DK137329B (da) Analogifremgangsmåde til fremstilling af 2-karbalkoksyaminobenzimidazolderivater.
DK135775B (da) Analogifremgangsmåde til fremstilling af mættede 3alfa-hydroxy-5alfa-pregnaner.
DK131868B (da) Analogifremgangsmåde til fremstilling af tri-p-toluensulfonatet af S-adenosyl-L-methionin.
DK132500B (da) Analogifremgangsmåde til fremstilling af 2beta, 16beta-diamino-5alfa-androstaner.
DK134604B (da) Fremgangsmåde til fremstilling af indenyl-3-acetoglucuronider.
DK138796B (da) Analogifremgangsmåde til fremstilling af 2-carboxypyrazin-4-oxidderivater.
DK137639B (da) Analogifremgangsmåde til fremstilling af 1-aminomethyl-2,2-diaryl-cyclopropancarboxamider.
DK129088B (da) Fremgangsmåde til fremstilling af peptider.
DK138230B (da) Analogifremgangsmåde til fremstilling af vincanolsalte.
DK138898B (da) Fremgangsmåde til fremstilling af N-phosphonomethylglycin.
DK140668B (da) Analogifremgangsmåde til fremstilling af kondenserede pyriminderivater.
DK131942B (da) Fremgangsmåde til fremstilling af delta4,16-11beta-hydroxy-3,20-diketopregnadiener.
DK131864B (da) Fremgangsmåde til fremstilling af pregnan-21-syrederivater.
DK132233B (da) Fremgangsmåde til fremstilling af antibiotikum A-2315.
DK131575B (da) Analogifremgangsmåde til fremstilling af 2beta-hydroxy-3alfa-aminosteroider.
DK138645B (da) Analogifremgangsmåde til fremstilling af sulfamoylfenyl-imidazolidiner.
DK135122B (da) Analogifremgangsmåde til fremstilling af 4-aryl-5-aminoalkyl-4-oxazolin-2-onderivater.
DK129657B (da) Analogifremgangsmåde til fremstilling af 3-methylpyrazol-5-carboxamider.
DK135166B (da) Analogifremgangsmåde til fremstilling af 2-methyl-5-nitro-imidazoler.
DK131855B (da) Fremgangsmåde til fremstilling af 3,4-dihydropyridoner.
DK134183B (da) Fremgangsmåde til fremstilling af cellulose-enzymkomplekser.
DK139677B (da) Fremgangsmåde til fremstilling af 7-benzoylindolin-2-oner.
DK134236B (da) Analogifremgangsmåde til fremstilling af 3-cycloalkoxy-16alfa-cyanopregn-5-en-20-oner.