DK1368041T3 - Vandigt amphotericin B-præparat - Google Patents
Vandigt amphotericin B-præparatInfo
- Publication number
- DK1368041T3 DK1368041T3 DK01923963T DK01923963T DK1368041T3 DK 1368041 T3 DK1368041 T3 DK 1368041T3 DK 01923963 T DK01923963 T DK 01923963T DK 01923963 T DK01923963 T DK 01923963T DK 1368041 T3 DK1368041 T3 DK 1368041T3
- Authority
- DK
- Denmark
- Prior art keywords
- amphotericin
- compositions
- aqueous
- preparation
- autoclaving
- Prior art date
Links
- APKFDSVGJQXUKY-KKGHZKTASA-N Amphotericin-B Natural products O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1C=CC=CC=CC=CC=CC=CC=C[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-KKGHZKTASA-N 0.000 title abstract 4
- APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 title abstract 4
- 229960003942 amphotericin b Drugs 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 abstract 5
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 208000037026 Invasive Fungal Infections Diseases 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN217MU2001 IN188924B (enExample) | 2001-03-01 | 2001-03-01 | |
| PCT/IN2001/000040 WO2002069983A1 (en) | 2001-03-01 | 2001-03-16 | Amphotericin b aqueous composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1368041T3 true DK1368041T3 (da) | 2005-01-17 |
Family
ID=11097223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01923963T DK1368041T3 (da) | 2001-03-01 | 2001-03-16 | Vandigt amphotericin B-præparat |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20040137049A1 (enExample) |
| EP (1) | EP1368041B1 (enExample) |
| JP (1) | JP2004523566A (enExample) |
| KR (1) | KR100810067B1 (enExample) |
| CN (1) | CN1255114C (enExample) |
| AT (1) | ATE274913T1 (enExample) |
| AU (1) | AU2001250643B2 (enExample) |
| BG (1) | BG108188A (enExample) |
| BR (1) | BR0116922A (enExample) |
| CA (1) | CA2438847A1 (enExample) |
| CZ (1) | CZ20032264A3 (enExample) |
| DE (1) | DE60105322T2 (enExample) |
| DK (1) | DK1368041T3 (enExample) |
| EA (1) | EA006241B1 (enExample) |
| ES (1) | ES2227172T3 (enExample) |
| IN (1) | IN188924B (enExample) |
| MX (1) | MXPA03007777A (enExample) |
| NZ (1) | NZ528281A (enExample) |
| PT (1) | PT1368041E (enExample) |
| SK (1) | SK10742003A3 (enExample) |
| WO (1) | WO2002069983A1 (enExample) |
| YU (1) | YU75403A (enExample) |
| ZA (1) | ZA200307307B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| JP2006069929A (ja) * | 2004-08-31 | 2006-03-16 | Konica Minolta Medical & Graphic Inc | 真菌症治療製剤およびその製造方法 |
| WO2006030450A2 (en) * | 2004-09-13 | 2006-03-23 | Bharat Serums & Vaccines Ltd. | Stable emulsion compositions for intravenous administration having antimicrobial preservative efficacy |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| CN100418536C (zh) * | 2005-04-06 | 2008-09-17 | 河南省眼科研究所 | 一种用于眼科的抗真菌药物组合物 |
| MX2008014870A (es) | 2006-05-30 | 2009-02-12 | Intarcia Therapeutics Inc | Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas. |
| EP2359808B1 (en) | 2006-08-09 | 2013-05-22 | Intarcia Therapeutics, Inc | Osmotic delivery systems and piston assemblies |
| CN104000779A (zh) | 2007-04-23 | 2014-08-27 | 精达制药公司 | 促胰岛素释放肽的混悬制剂及其应用 |
| WO2009102467A2 (en) | 2008-02-13 | 2009-08-20 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
| RU2753280C2 (ru) | 2009-09-28 | 2021-08-12 | Интарсия Терапьютикс, Инк. | Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства |
| KR101629521B1 (ko) * | 2010-03-16 | 2016-06-13 | 우석대학교 산학협력단 | 난용성 약물 가용화 및 생체막 투과증진을 위한 알코올성 수상을 내상으로 하는 리포좀, 리포좀 조성물 및 리포좀의 제조방법 |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| CN102525921B (zh) * | 2012-02-06 | 2013-08-07 | 西安力邦制药有限公司 | 2,2’,6,6’-四异丙基-4,4’-二联苯酚脂微球制剂及其制备方法 |
| US9744191B2 (en) | 2012-03-19 | 2017-08-29 | Yale University | Antimicrobial compositions and methods |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| WO2016196851A2 (en) | 2015-06-03 | 2016-12-08 | Intarcia Therapeutics, Inc. | Implant placement and removal systems |
| EP3222324B1 (en) * | 2016-03-23 | 2020-05-13 | Wayne State University | Valproate as a topical anti-fungal treatment |
| JP7077237B2 (ja) | 2016-05-16 | 2022-05-30 | インターシア セラピューティクス，インコーポレイティド | グルカゴン受容体選択的ポリペプチド及びその使用方法 |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| KR20190104039A (ko) | 2017-01-03 | 2019-09-05 | 인타르시아 세라퓨틱스 인코포레이티드 | Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법 |
| CN108344811A (zh) * | 2017-01-24 | 2018-07-31 | 北京泰德制药股份有限公司 | 一种注射用脂质体中有机溶剂残留的检测方法 |
| CN108309955B (zh) * | 2018-04-27 | 2020-06-02 | 武昌理工学院 | 一种聚明胶肽结合型紫杉醇纳米颗粒的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1338736C (fr) * | 1986-12-05 | 1996-11-26 | Roger Baurain | Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation |
| US5616334A (en) * | 1987-03-05 | 1997-04-01 | The Liposome Company, Inc. | Low toxicity drug-lipid systems |
| US5100662A (en) * | 1989-08-23 | 1992-03-31 | The Liposome Company, Inc. | Steroidal liposomes exhibiting enhanced stability |
| FR2651680B1 (fr) * | 1989-09-14 | 1991-12-27 | Medgenix Group Sa | Nouveau procede de preparation de microparticules lipidiques. |
| US5580575A (en) * | 1989-12-22 | 1996-12-03 | Imarx Pharmaceutical Corp. | Therapeutic drug delivery systems |
| JP3956402B2 (ja) * | 1996-03-04 | 2007-08-08 | 日本油脂株式会社 | アンホテリシンｂ運搬体 |
| US6180136B1 (en) * | 1998-11-10 | 2001-01-30 | Idexx Laboratories, Inc. | Phospholipid-coated microcrystals for the sustained release of pharmacologically active compounds and methods of their manufacture and use |
-
2001
- 2001-03-01 IN IN217MU2001 patent/IN188924B/en unknown
- 2001-03-16 JP JP2002569158A patent/JP2004523566A/ja active Pending
- 2001-03-16 DK DK01923963T patent/DK1368041T3/da active
- 2001-03-16 CN CNB018231632A patent/CN1255114C/zh not_active Expired - Fee Related
- 2001-03-16 AT AT01923963T patent/ATE274913T1/de not_active IP Right Cessation
- 2001-03-16 AU AU2001250643A patent/AU2001250643B2/en not_active Ceased
- 2001-03-16 EA EA200300948A patent/EA006241B1/ru not_active IP Right Cessation
- 2001-03-16 WO PCT/IN2001/000040 patent/WO2002069983A1/en not_active Ceased
- 2001-03-16 DE DE60105322T patent/DE60105322T2/de not_active Expired - Lifetime
- 2001-03-16 CZ CZ20032264A patent/CZ20032264A3/cs unknown
- 2001-03-16 KR KR1020037011489A patent/KR100810067B1/ko not_active Expired - Fee Related
- 2001-03-16 PT PT01923963T patent/PT1368041E/pt unknown
- 2001-03-16 EP EP01923963A patent/EP1368041B1/en not_active Expired - Lifetime
- 2001-03-16 SK SK1074-2003A patent/SK10742003A3/sk unknown
- 2001-03-16 BR BR0116922-0A patent/BR0116922A/pt active Search and Examination
- 2001-03-16 ES ES01923963T patent/ES2227172T3/es not_active Expired - Lifetime
- 2001-03-16 US US10/469,624 patent/US20040137049A1/en not_active Abandoned
- 2001-03-16 CA CA002438847A patent/CA2438847A1/en not_active Abandoned
- 2001-03-16 MX MXPA03007777A patent/MXPA03007777A/es active IP Right Grant
- 2001-03-16 NZ NZ528281A patent/NZ528281A/en not_active IP Right Cessation
- 2001-03-16 YU YU75403A patent/YU75403A/sh unknown
-
2003
- 2003-09-18 ZA ZA200307307A patent/ZA200307307B/en unknown
- 2003-09-23 BG BG108188A patent/BG108188A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60105322T2 (de) | 2005-09-15 |
| SK10742003A3 (sk) | 2004-01-08 |
| KR100810067B1 (ko) | 2008-03-05 |
| EP1368041B1 (en) | 2004-09-01 |
| DE60105322D1 (de) | 2004-10-07 |
| EP1368041A1 (en) | 2003-12-10 |
| MXPA03007777A (es) | 2003-12-08 |
| BG108188A (bg) | 2004-09-30 |
| AU2001250643B2 (en) | 2007-03-22 |
| EA200300948A1 (ru) | 2004-04-29 |
| CZ20032264A3 (cs) | 2003-12-17 |
| YU75403A (sh) | 2006-05-25 |
| EA006241B1 (ru) | 2005-10-27 |
| IN188924B (enExample) | 2002-11-23 |
| CN1505519A (zh) | 2004-06-16 |
| NZ528281A (en) | 2006-11-30 |
| WO2002069983A1 (en) | 2002-09-12 |
| US20040137049A1 (en) | 2004-07-15 |
| CN1255114C (zh) | 2006-05-10 |
| JP2004523566A (ja) | 2004-08-05 |
| ES2227172T3 (es) | 2005-04-01 |
| PT1368041E (pt) | 2005-01-31 |
| KR20040018337A (ko) | 2004-03-03 |
| ATE274913T1 (de) | 2004-09-15 |
| BR0116922A (pt) | 2004-04-27 |
| ZA200307307B (en) | 2004-04-20 |
| CA2438847A1 (en) | 2002-09-12 |
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