DK136710C - Fremgangsmaade til fremstilling af symmetriske carotinoider - Google Patents

Fremgangsmaade til fremstilling af symmetriske carotinoider

Info

Publication number
DK136710C
DK136710C DK55876A DK55876A DK136710C DK 136710 C DK136710 C DK 136710C DK 55876 A DK55876 A DK 55876A DK 55876 A DK55876 A DK 55876A DK 136710 C DK136710 C DK 136710C
Authority
DK
Denmark
Prior art keywords
carotinoids
symmetric
procedure
preparation
symmetric carotinoids
Prior art date
Application number
DK55876A
Other languages
Danish (da)
English (en)
Other versions
DK55876A (da
DK136710B (da
Inventor
B Schulz
J Paust
J Schneider
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of DK55876A publication Critical patent/DK55876A/da
Publication of DK136710B publication Critical patent/DK136710B/da
Application granted granted Critical
Publication of DK136710C publication Critical patent/DK136710C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/32—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen
    • C07C1/321—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen the hetero-atom being a non-metal atom
    • C07C1/324—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen the hetero-atom being a non-metal atom the hetero-atom being a phosphorus atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/21—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5428—Acyclic unsaturated phosphonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK55876A 1975-02-12 1976-02-11 Fremgangsmaade til fremstilling af symmetriske carotinoider DK136710C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2505869A DE2505869C3 (de) 1975-02-12 1975-02-12 Verfahren zur Herstellung von symmetrischen Carotinoiden

Publications (3)

Publication Number Publication Date
DK55876A DK55876A (da) 1976-08-13
DK136710B DK136710B (da) 1977-11-14
DK136710C true DK136710C (da) 1978-04-24

Family

ID=5938693

Family Applications (1)

Application Number Title Priority Date Filing Date
DK55876A DK136710C (da) 1975-02-12 1976-02-11 Fremgangsmaade til fremstilling af symmetriske carotinoider

Country Status (11)

Country Link
US (1) US4105855A (xx)
JP (1) JPS5910659B2 (xx)
BE (1) BE838497A (xx)
CA (1) CA1058625A (xx)
CH (1) CH625212A5 (xx)
DE (1) DE2505869C3 (xx)
DK (1) DK136710C (xx)
FR (1) FR2300760A1 (xx)
GB (1) GB1529102A (xx)
IT (1) IT1053819B (xx)
NL (1) NL186316C (xx)

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DE3244272A1 (de) * 1982-11-30 1984-05-30 Basf Ag, 6700 Ludwigshafen (omega),(omega)-diacyloxy-2,6-dimethyl-octatriencarbonsaeureester und -aldehyde, verfahren zu ihrer herstellung und verwendung zur synthese von terpenverbindungen
US4568757A (en) * 1984-01-30 1986-02-04 Research Triangle Institute Configurationally locked retinoids
JPS61103158U (xx) * 1984-12-14 1986-07-01
US5225604A (en) * 1989-11-27 1993-07-06 Neurosearch A/S Hydroxycarbonyl derivatives and process for making the same
DK595489D0 (da) * 1989-11-27 1989-11-27 Neurosearch As Hydroxycarbonylderivater og fremgangsmaade til fremstilling af samme
US5185468A (en) * 1990-06-14 1993-02-09 Kuraray Company Ltd. Process for producing β-carotene, and intermediate compounds useful for the process
DE4112272A1 (de) * 1991-04-15 1992-10-22 Basf Ag 2,5-bis-(1',1'-dialkoxy-2'-propyl)-2,5- dihydrofurane, verfahren zu deren herstellung sowie deren verwendung zur herstellung von carotinoiden
US5475006A (en) * 1994-08-10 1995-12-12 National Research Council Of Canada Extensively oxidized derivatives of carotenoids, retinoids and related conjugated polyenes useful as non-toxic cell-differentiation inducers, anti-proliferative agents, and anti-tumor agents
US7132458B2 (en) 1994-08-10 2006-11-07 Chemaphor Inc. Oxidized carotenoid fractions and ketoaldehyde useful as cell-differentiation inducers, cytostatic agents, and anti-tumor agents
US5858700A (en) * 1997-04-03 1999-01-12 Kemin Foods, Lc Process for the isolation and purification of lycopene crystals
US5959138A (en) * 1997-11-25 1999-09-28 Industrial Organica S.A. De C.V. Short chain diesters and process for making the same
US6191293B1 (en) * 1998-04-20 2001-02-20 Inexa, Industria Extractora C.A. Trans-xanthophyll ester concentrates of enhanced purity and methods of making same
JP2001114756A (ja) * 1999-10-12 2001-04-24 Sumitomo Chem Co Ltd β−カロチンの製造方法
KR100365696B1 (ko) * 2000-03-02 2002-12-26 구상호 카로틴계 폴리엔 사슬 구조 화합물의 제조방법
US7078045B2 (en) * 2000-03-02 2006-07-18 Sang-Geon Kim Pharmaceutical composition for treatment and prevention of liver fibrosis and cirrhosis
US20030191137A1 (en) * 2000-04-07 2003-10-09 Sang-Geon Kim Prophylactic and therapeutic use of oltipraz as an antifibrotic and anticirrhotic agent in the liver and pharmaceutical composition containing oltipraz
KR20030067935A (ko) * 2002-02-09 2003-08-19 김상건 올티프라즈를 포함하는 간경화(간경변증) 치료를 위한 간 조직 재생용 제약 조성물
EP1253131A1 (en) * 2001-04-24 2002-10-30 Aventis Animal Nutrition S.A. Process for the preparation of an xanthophyll
ES2195758B1 (es) 2001-12-31 2005-03-01 Antibioticos, S.A.U. Procedimiento mejorado de produccion de licopeno mediante la fermentacion de cepas seleccionadas de blakeslea trispora, formulaciones y usos del licopeno obtenido.
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
JP2005518453A (ja) * 2002-02-25 2005-06-23 ディフュージョン・ファーマシューティカルズ・エルエルシー 二極性トランスカロテノイド塩およびそれらの使用
EP1556390A4 (en) * 2002-04-05 2007-12-26 Univ South Alabama FUNCTIONALIZED IONIC LIQUIDS AND METHODS OF USE
CN1703392A (zh) * 2002-10-25 2005-11-30 普罗德麦克斯公司 由酯化玉米黄质制备酯化虾青素的方法
DE10359434A1 (de) 2003-12-17 2005-07-21 Basf Ag Verfahren zur Herstellung von Phosphoniumsalzen
US7351424B2 (en) 2004-07-22 2008-04-01 Bio Lut S.A. De C.V. Enhanced purity trans-lutein-ester compositions and methods of making same
KR101327590B1 (ko) 2004-09-28 2013-11-12 체마폴, 인코포레이티드. 체중 증가 및 사료 전환을 촉진하는 조성물 및 방법
EP2540696B1 (en) * 2005-02-24 2020-01-01 Diffusion Pharmaceuticals LLC Trans carotenoids, formulation and uses
US20070065487A1 (en) * 2005-09-21 2007-03-22 Bio Lut S.A. De C.V. Trans-lutein xantophyll ester of high purity and high bioavailability in micellar solution and a process for the preparation thereof
WO2007043046A2 (en) * 2005-10-11 2007-04-19 Lycored Ltd. Carotenoid oxidation products as chemopreventive and chemotherapeutic agents
CN101041631B (zh) * 2006-03-24 2010-05-12 浙江医药股份有限公司维生素厂 改进的β-胡萝卜素合成工艺
KR101570131B1 (ko) 2007-04-13 2015-11-18 디퓨젼 파마슈티컬즈 엘엘씨 양극성 트랜스 카로티노이드의 말초혈관질환 치료와 예방을 위한 용도
NZ585620A (en) * 2007-10-26 2013-03-28 Ca Nat Research Council Compositions and methods for enhancing immune response
JP2011502125A (ja) * 2007-10-31 2011-01-20 ディフュージョン・ファーマシューティカルズ・エルエルシー 小分子拡散を促進する新しい種類の治療法
WO2009112506A1 (en) * 2008-03-11 2009-09-17 Dsm Ip Assets B.V. Novel use of carotenoid (ester)s
WO2010124391A1 (en) 2009-04-30 2010-11-04 Chemaphor Inc. Methods and compositions for improving the health of animals
EP2445339B1 (en) 2009-06-22 2019-08-07 Diffusion Pharmaceuticals LLC Diffusion enhancing compound and its use with a thrombolytic
CN105287473A (zh) 2010-06-02 2016-02-03 扩散药品有限公司 包含双极性反式类胡萝卜素的组合物及其应用
CN103288875A (zh) * 2013-05-24 2013-09-11 广州巨元生化有限公司 一种维生素a磷盐的制备方法
WO2015097717A2 (en) * 2013-12-23 2015-07-02 Laurus Labs Private Limited AN IMPROVED PROCESS FOR THE PREPARATION OF β-CAROTENE
AU2015365650B2 (en) * 2014-12-15 2021-02-25 Enpro Subsea Limited Apparatus, systems and methods for oil and gas operations
WO2017165667A1 (en) 2016-03-24 2017-09-28 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer
CN110452147B (zh) * 2019-07-30 2021-07-23 万华化学集团股份有限公司 一种β-胡萝卜素的制备方法
WO2022056827A1 (zh) * 2020-09-18 2022-03-24 厦门金达威维生素有限公司 一种β-胡萝卜素的制备方法
CN113292467B (zh) * 2021-06-09 2023-01-10 安徽智新生化有限公司 一种含醇碱液提纯维生素a油母液的方法
CN113651743B (zh) * 2021-08-30 2023-03-14 万华化学集团股份有限公司 一种β-胡萝卜素的制备方法
CN114292218B (zh) * 2022-01-06 2023-01-13 万华化学集团股份有限公司 一种以VA的C20磷盐为原料合成β-胡萝卜素的方法

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Publication number Priority date Publication date Assignee Title
DE1148542B (de) * 1961-10-28 1963-05-16 Hoechst Ag Verfahren zur Herstellung von ª‰-Carotin

Also Published As

Publication number Publication date
DE2505869B2 (de) 1977-07-28
JPS5910659B2 (ja) 1984-03-10
DE2505869A1 (de) 1976-08-26
BE838497A (fr) 1976-08-12
CA1058625A (en) 1979-07-17
NL186316C (nl) 1990-11-01
DK55876A (da) 1976-08-13
FR2300760B1 (xx) 1980-01-25
US4105855A (en) 1978-08-08
JPS51101962A (xx) 1976-09-08
IT1053819B (it) 1981-10-10
GB1529102A (en) 1978-10-18
DK136710B (da) 1977-11-14
NL7601401A (nl) 1976-08-16
FR2300760A1 (fr) 1976-09-10
DE2505869C3 (de) 1978-05-18
NL186316B (nl) 1990-06-01
CH625212A5 (xx) 1981-09-15

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