FR2300760A1 - Procede de preparation de carotenoides symetriques - Google Patents

Procede de preparation de carotenoides symetriques

Info

Publication number
FR2300760A1
FR2300760A1 FR7603404A FR7603404A FR2300760A1 FR 2300760 A1 FR2300760 A1 FR 2300760A1 FR 7603404 A FR7603404 A FR 7603404A FR 7603404 A FR7603404 A FR 7603404A FR 2300760 A1 FR2300760 A1 FR 2300760A1
Authority
FR
France
Prior art keywords
preparation
carotenoids
symmetric
symmetric carotenoids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7603404A
Other languages
English (en)
Other versions
FR2300760B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of FR2300760A1 publication Critical patent/FR2300760A1/fr
Application granted granted Critical
Publication of FR2300760B1 publication Critical patent/FR2300760B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/32Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen
    • C07C1/321Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen the hetero-atom being a non-metal atom
    • C07C1/324Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from compounds containing hetero-atoms other than or in addition to oxygen or halogen the hetero-atom being a non-metal atom the hetero-atom being a phosphorus atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/515Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/21Unsaturated compounds having —CHO groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5428Acyclic unsaturated phosphonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7603404A 1975-02-12 1976-02-09 Procede de preparation de carotenoides symetriques Granted FR2300760A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2505869A DE2505869C3 (de) 1975-02-12 1975-02-12 Verfahren zur Herstellung von symmetrischen Carotinoiden

Publications (2)

Publication Number Publication Date
FR2300760A1 true FR2300760A1 (fr) 1976-09-10
FR2300760B1 FR2300760B1 (fr) 1980-01-25

Family

ID=5938693

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7603404A Granted FR2300760A1 (fr) 1975-02-12 1976-02-09 Procede de preparation de carotenoides symetriques

Country Status (11)

Country Link
US (1) US4105855A (fr)
JP (1) JPS5910659B2 (fr)
BE (1) BE838497A (fr)
CA (1) CA1058625A (fr)
CH (1) CH625212A5 (fr)
DE (1) DE2505869C3 (fr)
DK (1) DK136710C (fr)
FR (1) FR2300760A1 (fr)
GB (1) GB1529102A (fr)
IT (1) IT1053819B (fr)
NL (1) NL186316C (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112502A2 (fr) * 1982-11-30 1984-07-04 BASF Aktiengesellschaft Esters carboxyliques et aldéhydes du oméga,oméga-diacyloxy-2,6-diméthyl-octatriène, procédé de préparation et utilisation dans la synthèse de composés terpéniques

Families Citing this family (45)

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Publication number Priority date Publication date Assignee Title
US4568757A (en) * 1984-01-30 1986-02-04 Research Triangle Institute Configurationally locked retinoids
JPS61103158U (fr) * 1984-12-14 1986-07-01
US5225604A (en) * 1989-11-27 1993-07-06 Neurosearch A/S Hydroxycarbonyl derivatives and process for making the same
DK595489D0 (da) * 1989-11-27 1989-11-27 Neurosearch As Hydroxycarbonylderivater og fremgangsmaade til fremstilling af samme
US5185468A (en) * 1990-06-14 1993-02-09 Kuraray Company Ltd. Process for producing β-carotene, and intermediate compounds useful for the process
DE4112272A1 (de) * 1991-04-15 1992-10-22 Basf Ag 2,5-bis-(1',1'-dialkoxy-2'-propyl)-2,5- dihydrofurane, verfahren zu deren herstellung sowie deren verwendung zur herstellung von carotinoiden
US5475006A (en) * 1994-08-10 1995-12-12 National Research Council Of Canada Extensively oxidized derivatives of carotenoids, retinoids and related conjugated polyenes useful as non-toxic cell-differentiation inducers, anti-proliferative agents, and anti-tumor agents
US7132458B2 (en) 1994-08-10 2006-11-07 Chemaphor Inc. Oxidized carotenoid fractions and ketoaldehyde useful as cell-differentiation inducers, cytostatic agents, and anti-tumor agents
US5858700A (en) * 1997-04-03 1999-01-12 Kemin Foods, Lc Process for the isolation and purification of lycopene crystals
US5959138A (en) * 1997-11-25 1999-09-28 Industrial Organica S.A. De C.V. Short chain diesters and process for making the same
US6191293B1 (en) 1998-04-20 2001-02-20 Inexa, Industria Extractora C.A. Trans-xanthophyll ester concentrates of enhanced purity and methods of making same
JP2001114756A (ja) * 1999-10-12 2001-04-24 Sumitomo Chem Co Ltd β−カロチンの製造方法
KR100365696B1 (ko) * 2000-03-02 2002-12-26 구상호 카로틴계 폴리엔 사슬 구조 화합물의 제조방법
US7078045B2 (en) * 2000-03-02 2006-07-18 Sang-Geon Kim Pharmaceutical composition for treatment and prevention of liver fibrosis and cirrhosis
KR20030067935A (ko) * 2002-02-09 2003-08-19 김상건 올티프라즈를 포함하는 간경화(간경변증) 치료를 위한 간 조직 재생용 제약 조성물
KR100404303B1 (ko) * 2000-04-07 2003-11-03 김상건 올티프라즈의 간섬유화 및 간경화 진행의 예방 및치료제로서의 용도 및 올티프라즈를 주성분으로 함유하는제약 조성물
EP1253131A1 (fr) * 2001-04-24 2002-10-30 Aventis Animal Nutrition S.A. Procédé de préparation de xanthophylles
ES2195758B1 (es) 2001-12-31 2005-03-01 Antibioticos, S.A.U. Procedimiento mejorado de produccion de licopeno mediante la fermentacion de cepas seleccionadas de blakeslea trispora, formulaciones y usos del licopeno obtenido.
US7759506B2 (en) * 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
IL163685A0 (en) * 2002-02-25 2005-12-18 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
EP2243539A3 (fr) * 2002-04-05 2011-06-01 University Of South Alabama Liquides ioniques fonctionnalisés et leurs procédés d'utilisation
EP1563081A4 (fr) * 2002-10-25 2005-10-26 Procede de production d'astaxanthine esterifiee a partir de zeaxanthine esterifiee
DE10359434A1 (de) 2003-12-17 2005-07-21 Basf Ag Verfahren zur Herstellung von Phosphoniumsalzen
US7351424B2 (en) 2004-07-22 2008-04-01 Bio Lut S.A. De C.V. Enhanced purity trans-lutein-ester compositions and methods of making same
BRPI0516202A (pt) 2004-09-28 2008-08-26 Chemaphor Inc produto para alimentação de um animal, uso, kit e método de preparação deste produto
EA017982B1 (ru) 2005-02-24 2013-04-30 ДИФФЬЮЖН ФАРМАСЬЮТИКАЛЗ ЭлЭлСи Фармацевтическая композиция на основе транскаротиноидов и способы лечения опухоли
US20070065487A1 (en) * 2005-09-21 2007-03-22 Bio Lut S.A. De C.V. Trans-lutein xantophyll ester of high purity and high bioavailability in micellar solution and a process for the preparation thereof
CA2625433A1 (fr) * 2005-10-11 2007-04-19 Lycored Ltd. Produits d'oxydation des carotenoides utilises en tant qu'agents chimiopreventifs et chimiotherapeutiques
CN101041631B (zh) * 2006-03-24 2010-05-12 浙江医药股份有限公司维生素厂 改进的β-胡萝卜素合成工艺
EP2146948A4 (fr) 2007-04-13 2010-08-04 Diffusion Pharmaceuticals Llc Utilisation de transcaroténoïdes bipolaires en tant que traitement préalable et dans le traitement de pathologies vasculaires périphériques
JP2011500733A (ja) * 2007-10-26 2011-01-06 ケマファー インコーポレーテッド 免疫応答を増強するための組成物および方法
AU2008319225B2 (en) * 2007-10-31 2016-09-29 Diffusion Pharmaceuticals Llc A new class of therapeutics that enhance small molecule diffusion
US8709110B2 (en) * 2008-03-11 2014-04-29 Dsm Ip Assets B.V. Use of carotenoid (ester)s
EP2424512B1 (fr) 2009-04-30 2020-06-03 Avivagen Inc. Procédés et compositions pour améliorer la santé d'animaux
US10130689B2 (en) 2009-06-22 2018-11-20 Diffusion Pharmaceuticals Llc Diffusion enhancing compounds and their use alone or with thrombolytics
EP2575487B1 (fr) 2010-06-02 2017-10-18 Diffusion Pharmaceuticals Llc Formes pharmaceutiques orales à base de caroténoïdes trans bipolaires
CN103288875A (zh) * 2013-05-24 2013-09-11 广州巨元生化有限公司 一种维生素a磷盐的制备方法
WO2015097717A2 (fr) * 2013-12-23 2015-07-02 Laurus Labs Private Limited Procédé amélioré de préparation de β-carotène
BR122018076131B1 (pt) * 2014-12-15 2023-01-17 Enpro Subsea Limited Aparelho, sistema e método para operações de petróleo e gás
EP3432929A4 (fr) 2016-03-24 2019-11-27 Diffusion Pharmaceuticals LLC Utilisation de caroténoïdes trans bipolaires avec une chimiothérapie et une radiothérapie en vue du traitement d'un cancer
CN110452147B (zh) * 2019-07-30 2021-07-23 万华化学集团股份有限公司 一种β-胡萝卜素的制备方法
WO2022056827A1 (fr) * 2020-09-18 2022-03-24 厦门金达威维生素有限公司 PROCÉDÉ DE PRÉPARATION DE β-CAROTÈNE
CN113292467B (zh) * 2021-06-09 2023-01-10 安徽智新生化有限公司 一种含醇碱液提纯维生素a油母液的方法
CN113651743B (zh) * 2021-08-30 2023-03-14 万华化学集团股份有限公司 一种β-胡萝卜素的制备方法
CN114292218B (zh) * 2022-01-06 2023-01-13 万华化学集团股份有限公司 一种以VA的C20磷盐为原料合成β-胡萝卜素的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1148542B (de) * 1961-10-28 1963-05-16 Hoechst Ag Verfahren zur Herstellung von ª‰-Carotin

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112502A2 (fr) * 1982-11-30 1984-07-04 BASF Aktiengesellschaft Esters carboxyliques et aldéhydes du oméga,oméga-diacyloxy-2,6-diméthyl-octatriène, procédé de préparation et utilisation dans la synthèse de composés terpéniques
EP0112502A3 (en) * 1982-11-30 1984-09-05 Basf Aktiengesellschaft Carboxylic esters and aldehydes of omega,omega-diacyloxy-2,6-dimethyl octatriene, process for their preparation and their use in the synthesis of terpene compounds

Also Published As

Publication number Publication date
JPS5910659B2 (ja) 1984-03-10
US4105855A (en) 1978-08-08
IT1053819B (it) 1981-10-10
BE838497A (fr) 1976-08-12
FR2300760B1 (fr) 1980-01-25
DK136710C (da) 1978-04-24
DE2505869B2 (de) 1977-07-28
DK136710B (da) 1977-11-14
CA1058625A (fr) 1979-07-17
GB1529102A (en) 1978-10-18
NL186316C (nl) 1990-11-01
NL186316B (nl) 1990-06-01
CH625212A5 (fr) 1981-09-15
DE2505869A1 (de) 1976-08-26
NL7601401A (nl) 1976-08-16
DE2505869C3 (de) 1978-05-18
JPS51101962A (fr) 1976-09-08
DK55876A (da) 1976-08-13

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