DK1339705T3 - Fremgangsmåde til fremstilling af liponsyre og dihydroliponsyre - Google Patents

Fremgangsmåde til fremstilling af liponsyre og dihydroliponsyre

Info

Publication number
DK1339705T3
DK1339705T3 DK01990455T DK01990455T DK1339705T3 DK 1339705 T3 DK1339705 T3 DK 1339705T3 DK 01990455 T DK01990455 T DK 01990455T DK 01990455 T DK01990455 T DK 01990455T DK 1339705 T3 DK1339705 T3 DK 1339705T3
Authority
DK
Denmark
Prior art keywords
sub
acid
sulfur
preparation
sodium sulfide
Prior art date
Application number
DK01990455T
Other languages
English (en)
Inventor
Martin Jochen Klatt
Joachim Paust
Markus Niebel
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK1339705T3 publication Critical patent/DK1339705T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/04Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK01990455T 2000-11-30 2001-11-29 Fremgangsmåde til fremstilling af liponsyre og dihydroliponsyre DK1339705T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10059718 2000-11-30

Publications (1)

Publication Number Publication Date
DK1339705T3 true DK1339705T3 (da) 2006-10-09

Family

ID=7665405

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01990455T DK1339705T3 (da) 2000-11-30 2001-11-29 Fremgangsmåde til fremstilling af liponsyre og dihydroliponsyre

Country Status (10)

Country Link
US (1) US7109362B2 (da)
EP (1) EP1339705B1 (da)
JP (1) JP2004514716A (da)
AT (1) ATE328877T1 (da)
AU (1) AU2002229576A1 (da)
CA (1) CA2430073A1 (da)
DE (1) DE50110077D1 (da)
DK (1) DK1339705T3 (da)
ES (1) ES2266299T3 (da)
WO (1) WO2002044163A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10201464B4 (de) * 2002-01-16 2005-06-16 Viatris Gmbh & Co. Kg Verfahren zur Herstellung reiner Thioctsäure
DE10255242A1 (de) 2002-11-26 2004-06-03 Basf Ag Verfahren zur Reinigung von Liponsäure
US20070299093A1 (en) * 2005-01-27 2007-12-27 Alma Mater Studiorum-Universitá Di Bologna Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation
EA200701584A1 (ru) * 2005-01-27 2008-02-28 Альма Матер Студиорум - Университа' Ди Болонья Органические соединения, применяемые для лечения болезни альцгеймера, их применение и способ получения
US7776915B2 (en) * 2005-03-24 2010-08-17 Tracie Martyn International, Llc Topical formulations and methods of use
US20100310484A1 (en) * 2007-06-29 2010-12-09 Innovactiv Inc. Novel peptides, use thereof in cosmetic and cosmeceutic applications, and compositions comprising same
US20090078581A1 (en) * 2007-09-24 2009-03-26 Applied Intellectual Capital Configurations and Methods of Reduction of Lipoic Acid
KR20130006464A (ko) 2010-03-09 2013-01-16 노버스 인터내쇼날 인코포레이티드 락톤 중간체를 통한 호모세린으로부터 메티오닌 또는 셀레노메티오닌의 제조
US9944960B2 (en) 2015-11-17 2018-04-17 Premier Research Labs, Lp Process for microbial production of dihydrolipoic acid and extraction of dihydrolipoic acid with edible oils
DE102017000811A1 (de) 2017-01-28 2018-08-02 Alzchem Trostberg Gmbh Verfahren zur Herstellung von Dihydroliponsäure
CN111377840A (zh) * 2018-12-29 2020-07-07 江苏同禾药业有限公司 一种r-(+)-二氢硫辛酸的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2115589T3 (es) 1989-11-09 1998-07-01 Asta Medica Ag Medicamento que contiene acido r-alfa-liponico o acido s-alfa-liponico como sustancia activa.
DE4037440A1 (de) * 1990-11-24 1992-05-27 Basf Ag Verfahren zur herstellung von (6s)-6,8-dihydroxyoctansaeureestern
DE4137773A1 (de) 1991-11-16 1993-05-19 Degussa Herstellung und verwendung von salzen der reinen enantiomere der (alpha)-liponsaeure
DE4343593C2 (de) 1993-12-21 1998-05-20 Asta Medica Ag Verwendung von R-(+)-alpha-Liponsäure, R-(-)-Dihydroliponsäure oder der Metabolite sowie deren Salze, Ester, Amide zur Behandlung kompensierter und dekompensierter Insulinresistenz
DE4343592C2 (de) 1993-12-21 1998-04-16 Asta Medica Ag Verwendung von R-(+)-alpha-Liponsäure und dessen Metaboliten in Form der freien Säure oder als Salze oder Ester oder Amide zur Behandlung von Glukosestoffwechselstörungen des zentralen Nervensystems
DE19834608A1 (de) * 1998-07-31 2000-02-03 Basf Ag Kristallmodifikation der Liponsäure
DE69920497T2 (de) 1998-10-26 2006-02-09 The Research Foundation Of State University Of New York Liponsaürederivate und deren verwendung bei der behandlung von krankheiten
US6204288B1 (en) 1999-03-08 2001-03-20 The University Of Mississippi 1,2-dithiolane derivatives
AR042572A1 (es) 1999-04-02 2005-06-29 Sod Conseils Rech Applic Derivados de acido lipoico, procedimiento para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y utilizacion de dichos derivados para la preparacion de los referidos medicamentos
CN1680364A (zh) * 2000-08-02 2005-10-12 巴斯福股份公司 硫辛酸和二氢硫辛酸的制备方法

Also Published As

Publication number Publication date
CA2430073A1 (en) 2002-06-06
US7109362B2 (en) 2006-09-19
WO2002044163A3 (de) 2003-01-30
AU2002229576A1 (en) 2002-06-11
DE50110077D1 (de) 2006-07-20
JP2004514716A (ja) 2004-05-20
ATE328877T1 (de) 2006-06-15
WO2002044163A2 (de) 2002-06-06
EP1339705A2 (de) 2003-09-03
US20050101669A1 (en) 2005-05-12
ES2266299T3 (es) 2007-03-01
EP1339705B1 (de) 2006-06-07

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