DK1337285T3 - Implantater med phosphazen-holdig belægning - Google Patents

Implantater med phosphazen-holdig belægning

Info

Publication number
DK1337285T3
DK1337285T3 DK01976054T DK01976054T DK1337285T3 DK 1337285 T3 DK1337285 T3 DK 1337285T3 DK 01976054 T DK01976054 T DK 01976054T DK 01976054 T DK01976054 T DK 01976054T DK 1337285 T3 DK1337285 T3 DK 1337285T3
Authority
DK
Denmark
Prior art keywords
phosphazene
containing coating
phosphazane
antithrombogenic
partly
Prior art date
Application number
DK01976054T
Other languages
Danish (da)
English (en)
Inventor
Stefan Nagel
Michael Boxberger
Original Assignee
Braun Melsungen Ag
Polyzenix Ges Fuer Medizintech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braun Melsungen Ag, Polyzenix Ges Fuer Medizintech filed Critical Braun Melsungen Ag
Application granted granted Critical
Publication of DK1337285T3 publication Critical patent/DK1337285T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/068—Use of macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
DK01976054T 2000-08-11 2001-08-01 Implantater med phosphazen-holdig belægning DK1337285T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00117191A EP1179353A1 (fr) 2000-08-11 2000-08-11 Implants antithrombotiques avec un revêtement de polyphosphazène et d'un agent actif
PCT/EP2001/008913 WO2002013882A1 (fr) 2000-08-11 2001-08-01 Implants pourvus d'un revetement contenant du phosphazene

Publications (1)

Publication Number Publication Date
DK1337285T3 true DK1337285T3 (da) 2008-02-11

Family

ID=8169492

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01976054T DK1337285T3 (da) 2000-08-11 2001-08-01 Implantater med phosphazen-holdig belægning

Country Status (13)

Country Link
US (1) US20030157142A1 (fr)
EP (2) EP1179353A1 (fr)
JP (1) JP4886156B2 (fr)
KR (1) KR100809134B1 (fr)
CN (1) CN100467073C (fr)
AT (1) ATE374626T1 (fr)
AU (2) AU9544701A (fr)
BR (1) BR0113184B1 (fr)
CA (1) CA2424359C (fr)
DE (1) DE50113094D1 (fr)
DK (1) DK1337285T3 (fr)
ES (1) ES2296811T3 (fr)
WO (1) WO2002013882A1 (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001080919A2 (fr) 2000-04-11 2001-11-01 Polyzenix Gmbh Enveloppes et films en poly-tri-fluoro-ethoxypolyphosphazene
US20090004240A1 (en) * 2000-08-11 2009-01-01 Celonova Biosciences, Inc. Implants with a phosphazene-containing coating
DE10202467A1 (de) * 2002-01-23 2003-07-24 Polyzenix Gmbh Vorrichtung auf Basis von Nitinol, ein Verfahren zu dessen Herstellung sowie dessen Verwendung
DE10100961B4 (de) 2001-01-11 2005-08-04 Polyzenix Gmbh Körperverträglicher Werkstoff und mit diesem Werkstoff beschichtetes Substrat für die Züchtung von Zellen und künstlichen aus Zellen aufgebauten oder gewachsenen organischen Implantaten
US9080146B2 (en) 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
US20080228284A1 (en) * 2001-01-11 2008-09-18 Celonova Biosciences, Inc. Specific Polyphosphazene-Containing Three-Dimensional Bone Support Implants and Methods for Their Use
EP1432380B1 (fr) 2001-08-17 2006-09-27 Polyzenix GmbH Dispositif a base de nitinol comportant un revetement polyphosphate
CA2491282C (fr) * 2002-07-05 2013-02-12 Polyzenix Gmbh Implant pour le transport et la liberation d'agents pharmaceutiques actifs incorpores dans les polyphosphazenes et methodes connexes
US20080138433A1 (en) * 2002-07-05 2008-06-12 Celonova Biosciences, Inc. Vasodilator eluting blood storage and administration devices with a specific polyphosphazene coating and methods for their manufacture and use
US20050136093A1 (en) * 2002-07-05 2005-06-23 Polyzenix Gmbh Implant for transport and release for pharmacologically active agents as well as a process for producing the same
DE602004030892D1 (de) * 2003-03-26 2011-02-17 Celonova Biosciences Germany Gmbh Beschichtete dentalimplantate
US9107850B2 (en) 2004-10-25 2015-08-18 Celonova Biosciences, Inc. Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
US9114162B2 (en) 2004-10-25 2015-08-25 Celonova Biosciences, Inc. Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same
EP1804773B1 (fr) * 2004-10-25 2011-03-30 CeloNova BioSciences Germany GmbH Particules polymeres chargeables pour des applications therapeutiques et/ou diagnostiques et methode de preparation et d'utilisation de ces particules
CA2690539C (fr) 2006-10-10 2014-10-07 Celonova Biosciences, Inc. Valvule cardiaque bioprothetique a polyphosphazene
CN101032473B (zh) * 2007-04-05 2010-04-07 上海交通大学 三明治型药物缓释膜及其制备方法
CA2687031A1 (fr) * 2007-05-15 2008-11-20 Chameleon Biosurfaces Limited Revetements polymeres sur dispositifs medicaux
CA2694408C (fr) 2007-07-25 2014-01-07 Celonova Biosciences, Inc. Particules polymeriques chargeables a codage et taille de couleur pour applications therapeutiques et/ou diagnostiques, et procedes de preparation et d'utilisation de ces particules
DE102007038799A1 (de) * 2007-08-17 2009-02-19 Biotronik Vi Patent Ag Implantat aus einer biokorrodierbaren Magnesiumlegierung und mit einer Beschichtung aus einem biokorrodierbaren Polyphosphazen
WO2009110858A2 (fr) * 2007-10-31 2009-09-11 Celonova Biosciences, Inc. Dispositifs de manipulation de sang dynamique à élution de vasodilatateur, revêtus d’une couche spécifique de polyphospazène, procédés de fabrication et d’utilisation associés
WO2009058145A1 (fr) * 2007-10-31 2009-05-07 Celonova Biosciences, Inc. Dispositifs à stent intracavitaire dotés d'un revêtement de polyphosphazène spécifique, conçus pour une élution de vasodilatateur, et leurs procédés de fabrication et d'utilisation
EP2252218A4 (fr) * 2008-02-11 2012-06-06 Celonova Biosciences Inc Articles et dispositifs pour suture de tissus, et procédés connexes
WO2009105761A2 (fr) * 2008-02-22 2009-08-27 Celonova Biosciences, Inc. Matrices multifonctionnelles pour pansements et procédés associés
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
EP2616131A4 (fr) * 2010-09-16 2014-12-03 Univ Kyoto Spires chargées de statines destinées à accélérer l'organisation après la mise en place d'une spire endovasculaire dans un anévrisme
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9550011B2 (en) 2012-05-03 2017-01-24 Indiana University Research And Technology Corporation Surface coatings for biological implants and prostheses
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
CN113633435A (zh) 2016-01-29 2021-11-12 内奥瓦斯克迪亚拉公司 用于防止流出阻塞的假体瓣膜
CN113893064A (zh) 2016-11-21 2022-01-07 内奥瓦斯克迪亚拉公司 用于快速收回经导管心脏瓣膜递送系统的方法和系统
CA3073834A1 (fr) 2017-08-25 2019-02-28 Neovasc Tiara Inc. Prothese de valvule mitrale transcatheter a deploiement sequentiel
AU2019374743B2 (en) 2018-11-08 2022-03-03 Neovasc Tiara Inc. Ventricular deployment of a transcatheter mitral valve prosthesis
US11602429B2 (en) 2019-04-01 2023-03-14 Neovasc Tiara Inc. Controllably deployable prosthetic valve
WO2020210652A1 (fr) 2019-04-10 2020-10-15 Neovasc Tiara Inc. Valvule prothétique à circulation sanguine naturelle
CA3140925A1 (fr) 2019-05-20 2020-11-26 Neovasc Tiara Inc. Dispositif d'introduction avec mecanisme d'hemostase
AU2020295566B2 (en) 2019-06-20 2023-07-20 Neovasc Tiara Inc. Low profile prosthetic mitral valve

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311736A (en) * 1979-03-19 1982-01-19 The Kendall Company Article having organo-phosphonitrile rubber coating bonded to natural or synthetic rubber and method of making
US4341844A (en) * 1979-10-25 1982-07-27 The Kendall Company Article having organo-phosphonitrile rubber coating bonded to natural or synthetic rubber and method of making
US4318947A (en) * 1979-12-26 1982-03-09 The Kendall Company Polymer coating and curing process for catheters
US4424395A (en) * 1982-03-11 1984-01-03 The Dow Chemical Company Carbamates of biphenyls
US4451647A (en) * 1982-06-21 1984-05-29 Research Corporation Heparinized polyorganophosphazenes
US4480642A (en) * 1982-07-26 1984-11-06 Health Products Research, Inc. Dilation device for the cervix
JPS6038307A (ja) * 1983-08-11 1985-02-27 Nippon Daigaku 充填用複合材
US4911691A (en) * 1984-09-21 1990-03-27 Menlo Care, Inc. Assembly for adminstering IV solution
US4883699A (en) * 1984-09-21 1989-11-28 Menlo Care, Inc. Polymeric article having high tensile energy to break when hydrated
US4592755A (en) * 1985-06-11 1986-06-03 Ethyl Corporation Mammary implant
US4798876A (en) * 1985-11-12 1989-01-17 Tyndale Plains-Hunter Ltd. Hydrophilic polyurethane composition
US4880622A (en) * 1986-05-20 1989-11-14 Research Corporation Technologies, Inc. Water-soluble phosphazene polymers having pharmacological applications
US5634946A (en) * 1988-08-24 1997-06-03 Focal, Inc. Polymeric endoluminal paving process
US4975280A (en) * 1989-01-23 1990-12-04 Ethyl Corporation Bioerodable sustained release implants
US5439446A (en) * 1994-06-30 1995-08-08 Boston Scientific Corporation Stent and therapeutic delivery system
FR2679466B1 (fr) * 1991-07-25 1994-04-15 Ceramique Technique Membrane de filtration et procede de fabrication.
DE4138513A1 (de) * 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
US5464650A (en) * 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
ES2290074T3 (es) * 1993-07-19 2008-02-16 Angiotech Pharmaceuticals, Inc. Composiciones anti-angiogenicas que contienen taxol y un vehiculo no biodegradable y su uso.
US5716981A (en) * 1993-07-19 1998-02-10 Angiogenesis Technologies, Inc. Anti-angiogenic compositions and methods of use
WO1995028124A2 (fr) * 1994-04-08 1995-10-26 Atrix Laboratories, Inc. Systeme auxiliaire de polymeres pour dispositif medical
US5788979A (en) * 1994-07-22 1998-08-04 Inflow Dynamics Inc. Biodegradable coating with inhibitory properties for application to biocompatible materials
US5548060A (en) * 1994-08-08 1996-08-20 Penn State Research Foundation, Inc. Sulfonation of polyphosphazenes
US5605696A (en) * 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
DE19613048C2 (de) * 1995-03-30 1997-12-18 Michael Prof Dr Grunze Künstliche Implantate mit antithrombogenen Eigenschaften und Verfahren zu deren Herstellung
US5914388A (en) * 1995-04-26 1999-06-22 The Penn State Research Foundation Synthesis polyphosphazenes with controlled molecular weight and polydisperity
US5603722A (en) * 1995-06-06 1997-02-18 Quanam Medical Corporation Intravascular stent
CA2178541C (fr) * 1995-06-07 2009-11-24 Neal E. Fearnot Dispositif medical implantable
US6007573A (en) * 1996-09-18 1999-12-28 Microtherapeutics, Inc. Intracranial stent and method of use
US6254628B1 (en) * 1996-12-09 2001-07-03 Micro Therapeutics, Inc. Intracranial stent
US5707597A (en) * 1996-11-13 1998-01-13 Virus Research Institute, Inc. Polyhalophosphazene solutions stable against gelation
US5980972A (en) * 1996-12-20 1999-11-09 Schneider (Usa) Inc Method of applying drug-release coatings
US5814704A (en) * 1997-03-04 1998-09-29 Virus Research Institute, Inc. Recovery of polyphosphazene polyacids or acids salts thereof
US5843172A (en) * 1997-04-15 1998-12-01 Advanced Cardiovascular Systems, Inc. Porous medicated stent
US6273913B1 (en) * 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
US6077916A (en) * 1997-06-04 2000-06-20 The Penn State Research Foundation Biodegradable mixtures of polyphoshazene and other polymers
DE19744135C1 (de) * 1997-09-29 1999-03-25 Schering Ag Beschichtete medizinische Implantate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Restenoseprophylaxe
DE19743373A1 (de) * 1997-09-30 1999-04-15 Univ Heidelberg ·3··2·P-Polyphosphazen
US6485514B1 (en) * 1997-12-12 2002-11-26 Supergen, Inc. Local delivery of therapeutic agents
US20010029351A1 (en) * 1998-04-16 2001-10-11 Robert Falotico Drug combinations and delivery devices for the prevention and treatment of vascular disease
JP4583597B2 (ja) * 1998-05-05 2010-11-17 ボストン サイエンティフィック リミテッド 末端が滑らかなステント
US6254634B1 (en) * 1998-06-10 2001-07-03 Surmodics, Inc. Coating compositions
US5997301A (en) * 1998-10-20 1999-12-07 Linden; Lars Ake Treatment of tooth surfaces and substances therefor
US6958147B1 (en) * 1998-10-26 2005-10-25 Licentia Ltd Use of VEGF-C to prevent restenosis
US6258121B1 (en) * 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
US6790228B2 (en) * 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6503556B2 (en) * 2000-12-28 2003-01-07 Advanced Cardiovascular Systems, Inc. Methods of forming a coating for a prosthesis
US6203551B1 (en) * 1999-10-04 2001-03-20 Advanced Cardiovascular Systems, Inc. Chamber for applying therapeutic substances to an implant device
KR100315630B1 (ko) * 1999-11-17 2001-12-12 박호군 온도변화에 따라 상전이 거동을 갖는 분해성폴리포스파젠계 고분자 및 그 제조방법
CA2402949C (fr) * 2000-03-18 2009-09-08 Polyzenix Gmbh Derives de la polyphosphazene resistante aux bacteries et son utilisation
WO2001080919A2 (fr) * 2000-04-11 2001-11-01 Polyzenix Gmbh Enveloppes et films en poly-tri-fluoro-ethoxypolyphosphazene
US20020005206A1 (en) * 2000-05-19 2002-01-17 Robert Falotico Antiproliferative drug and delivery device
US6689807B1 (en) * 2000-06-08 2004-02-10 Caritas St. Elizabeth's Medical Center Of Boston, Inc. HMG CoA reductase inhibitors for promoting angiogenesis
US20020111590A1 (en) * 2000-09-29 2002-08-15 Davila Luis A. Medical devices, drug coatings and methods for maintaining the drug coatings thereon
US6863685B2 (en) * 2001-03-29 2005-03-08 Cordis Corporation Radiopacity intraluminal medical device
US6746773B2 (en) * 2000-09-29 2004-06-08 Ethicon, Inc. Coatings for medical devices
US8303609B2 (en) * 2000-09-29 2012-11-06 Cordis Corporation Coated medical devices
US7261735B2 (en) * 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
AU2002340749A1 (en) * 2001-05-04 2002-11-18 Concentric Medical Coated combination vaso-occlusive device
US7195640B2 (en) * 2001-09-25 2007-03-27 Cordis Corporation Coated medical devices for the treatment of vulnerable plaque
US20030065377A1 (en) * 2001-09-28 2003-04-03 Davila Luis A. Coated medical devices
US20030065345A1 (en) * 2001-09-28 2003-04-03 Kevin Weadock Anastomosis devices and methods for treating anastomotic sites
US6887270B2 (en) * 2002-02-08 2005-05-03 Boston Scientific Scimed, Inc. Implantable or insertable medical device resistant to microbial growth and biofilm formation

Also Published As

Publication number Publication date
KR100809134B1 (ko) 2008-02-29
CA2424359A1 (fr) 2003-02-06
US20030157142A1 (en) 2003-08-21
AU2001295447B2 (en) 2007-01-04
BR0113184B1 (pt) 2014-12-02
ATE374626T1 (de) 2007-10-15
AU9544701A (en) 2002-02-25
WO2002013882A1 (fr) 2002-02-21
ES2296811T3 (es) 2008-05-01
JP2004522461A (ja) 2004-07-29
EP1179353A1 (fr) 2002-02-13
DE50113094D1 (de) 2007-11-15
CA2424359C (fr) 2012-03-20
CN1469759A (zh) 2004-01-21
CN100467073C (zh) 2009-03-11
JP4886156B2 (ja) 2012-02-29
KR20030061780A (ko) 2003-07-22
EP1337285A1 (fr) 2003-08-27
BR0113184A (pt) 2003-07-01
EP1337285B1 (fr) 2007-10-03

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