BR0113184A - Implante artificial e processo para produzir o mesmo - Google Patents
Implante artificial e processo para produzir o mesmoInfo
- Publication number
- BR0113184A BR0113184A BR0113184-2A BR0113184A BR0113184A BR 0113184 A BR0113184 A BR 0113184A BR 0113184 A BR0113184 A BR 0113184A BR 0113184 A BR0113184 A BR 0113184A
- Authority
- BR
- Brazil
- Prior art keywords
- produce
- same
- artificial implant
- artificial
- implant
- Prior art date
Links
- 239000007943 implant Substances 0.000 title abstract 3
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 239000002831 pharmacologic agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/06—Use of macromolecular materials
- A61L33/068—Use of macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Abstract
"IMPLANTE ARTIFICIAL E PROCESSO PARA PRODUZIR O MESMO". A invenção refere-se a implantes artificiais com uma superfície biocompatível que é dotada de propriedades anti-trombóticas, contendo além disso um ingrediente farmacologicamente ativo e um processo para a produção do mesmo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00117191.7 | 2000-08-11 | ||
EP00117191A EP1179353A1 (de) | 2000-08-11 | 2000-08-11 | Antithrombogene Implantate mit Beschichtung aus Polyphosphazenen und einem pharmakologisch aktiven Wirkstoff |
PCT/EP2001/008913 WO2002013882A1 (de) | 2000-08-11 | 2001-08-01 | Implantate mit phosphazenhaltiger beschichtung |
Publications (2)
Publication Number | Publication Date |
---|---|
BR0113184A true BR0113184A (pt) | 2003-07-01 |
BR0113184B1 BR0113184B1 (pt) | 2014-12-02 |
Family
ID=8169492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0113184-2A BR0113184B1 (pt) | 2000-08-11 | 2001-08-01 | Implante artificial e processo para produzir o mesmo |
Country Status (13)
Country | Link |
---|---|
US (1) | US20030157142A1 (pt) |
EP (2) | EP1179353A1 (pt) |
JP (1) | JP4886156B2 (pt) |
KR (1) | KR100809134B1 (pt) |
CN (1) | CN100467073C (pt) |
AT (1) | ATE374626T1 (pt) |
AU (2) | AU9544701A (pt) |
BR (1) | BR0113184B1 (pt) |
CA (1) | CA2424359C (pt) |
DE (1) | DE50113094D1 (pt) |
DK (1) | DK1337285T3 (pt) |
ES (1) | ES2296811T3 (pt) |
WO (1) | WO2002013882A1 (pt) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001080919A2 (de) | 2000-04-11 | 2001-11-01 | Polyzenix Gmbh | Umhüllungen und folien aus poly-tri-fluor-ethoxypolyphosphazen |
US20090004240A1 (en) * | 2000-08-11 | 2009-01-01 | Celonova Biosciences, Inc. | Implants with a phosphazene-containing coating |
DE10202467A1 (de) * | 2002-01-23 | 2003-07-24 | Polyzenix Gmbh | Vorrichtung auf Basis von Nitinol, ein Verfahren zu dessen Herstellung sowie dessen Verwendung |
DE10100961B4 (de) | 2001-01-11 | 2005-08-04 | Polyzenix Gmbh | Körperverträglicher Werkstoff und mit diesem Werkstoff beschichtetes Substrat für die Züchtung von Zellen und künstlichen aus Zellen aufgebauten oder gewachsenen organischen Implantaten |
US9080146B2 (en) | 2001-01-11 | 2015-07-14 | Celonova Biosciences, Inc. | Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface |
US20080228284A1 (en) * | 2001-01-11 | 2008-09-18 | Celonova Biosciences, Inc. | Specific Polyphosphazene-Containing Three-Dimensional Bone Support Implants and Methods for Their Use |
EP1432380B1 (de) | 2001-08-17 | 2006-09-27 | Polyzenix GmbH | Vorrichtung auf basis von nitinol mit polyphosphazenüberzug |
CA2491282C (en) * | 2002-07-05 | 2013-02-12 | Polyzenix Gmbh | Implant for transport and release for pharmacologically active agents incorporated within polyphosphazenes and related methods |
US20080138433A1 (en) * | 2002-07-05 | 2008-06-12 | Celonova Biosciences, Inc. | Vasodilator eluting blood storage and administration devices with a specific polyphosphazene coating and methods for their manufacture and use |
US20050136093A1 (en) * | 2002-07-05 | 2005-06-23 | Polyzenix Gmbh | Implant for transport and release for pharmacologically active agents as well as a process for producing the same |
DE602004030892D1 (de) * | 2003-03-26 | 2011-02-17 | Celonova Biosciences Germany Gmbh | Beschichtete dentalimplantate |
US9107850B2 (en) | 2004-10-25 | 2015-08-18 | Celonova Biosciences, Inc. | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same |
US20210299056A9 (en) | 2004-10-25 | 2021-09-30 | Varian Medical Systems, Inc. | Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods |
US9114162B2 (en) | 2004-10-25 | 2015-08-25 | Celonova Biosciences, Inc. | Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same |
EP1804773B1 (en) * | 2004-10-25 | 2011-03-30 | CeloNova BioSciences Germany GmbH | Loadable polyphosphazene-comprising particles for therapeutic and/or diagnostic applications and methods of preparing and using the same |
CA2690539C (en) | 2006-10-10 | 2014-10-07 | Celonova Biosciences, Inc. | Bioprosthetic heart valve with polyphosphazene |
CN101032473B (zh) * | 2007-04-05 | 2010-04-07 | 上海交通大学 | 三明治型药物缓释膜及其制备方法 |
CA2687031A1 (en) * | 2007-05-15 | 2008-11-20 | Chameleon Biosurfaces Limited | Polymer coatings on medical devices |
CA2694408C (en) | 2007-07-25 | 2014-01-07 | Celonova Biosciences, Inc. | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same |
DE102007038799A1 (de) * | 2007-08-17 | 2009-02-19 | Biotronik Vi Patent Ag | Implantat aus einer biokorrodierbaren Magnesiumlegierung und mit einer Beschichtung aus einem biokorrodierbaren Polyphosphazen |
WO2009110858A2 (en) * | 2007-10-31 | 2009-09-11 | Celonova Biosciences, Inc. | Vasodilator eluting dynamic blood handling devices with a specific polyphosphazene coating and methods for their manufacture and use |
WO2009058145A1 (en) * | 2007-10-31 | 2009-05-07 | Celonova Biosciences, Inc. | Vasodilator eluting luminal stent devices with a specific polyphosphazene coating and methods for their manufacture and use |
EP2252218A4 (en) * | 2008-02-11 | 2012-06-06 | Celonova Biosciences Inc | FABRIC FASTENERS AND DEVICES AND RELEVANT PROCEDURES |
WO2009105761A2 (en) * | 2008-02-22 | 2009-08-27 | Celonova Biosciences, Inc. | Multi-functional wound dressing matrices and related methods |
US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
EP2616131A4 (en) * | 2010-09-16 | 2014-12-03 | Univ Kyoto | SPIELS LOADED WITH STATINES TO ACCELERATE THE ORGANIZATION AFTER THE PLACEMENT OF AN ENDOVASCULAR SPIRE IN ANEVISM |
US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US9550011B2 (en) | 2012-05-03 | 2017-01-24 | Indiana University Research And Technology Corporation | Surface coatings for biological implants and prostheses |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
CN113633435A (zh) | 2016-01-29 | 2021-11-12 | 内奥瓦斯克迪亚拉公司 | 用于防止流出阻塞的假体瓣膜 |
CN113893064A (zh) | 2016-11-21 | 2022-01-07 | 内奥瓦斯克迪亚拉公司 | 用于快速收回经导管心脏瓣膜递送系统的方法和系统 |
CA3073834A1 (en) | 2017-08-25 | 2019-02-28 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
AU2019374743B2 (en) | 2018-11-08 | 2022-03-03 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
US11602429B2 (en) | 2019-04-01 | 2023-03-14 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
WO2020210652A1 (en) | 2019-04-10 | 2020-10-15 | Neovasc Tiara Inc. | Prosthetic valve with natural blood flow |
CA3140925A1 (en) | 2019-05-20 | 2020-11-26 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
AU2020295566B2 (en) | 2019-06-20 | 2023-07-20 | Neovasc Tiara Inc. | Low profile prosthetic mitral valve |
Family Cites Families (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4311736A (en) * | 1979-03-19 | 1982-01-19 | The Kendall Company | Article having organo-phosphonitrile rubber coating bonded to natural or synthetic rubber and method of making |
US4341844A (en) * | 1979-10-25 | 1982-07-27 | The Kendall Company | Article having organo-phosphonitrile rubber coating bonded to natural or synthetic rubber and method of making |
US4318947A (en) * | 1979-12-26 | 1982-03-09 | The Kendall Company | Polymer coating and curing process for catheters |
US4424395A (en) * | 1982-03-11 | 1984-01-03 | The Dow Chemical Company | Carbamates of biphenyls |
US4451647A (en) * | 1982-06-21 | 1984-05-29 | Research Corporation | Heparinized polyorganophosphazenes |
US4480642A (en) * | 1982-07-26 | 1984-11-06 | Health Products Research, Inc. | Dilation device for the cervix |
JPS6038307A (ja) * | 1983-08-11 | 1985-02-27 | Nippon Daigaku | 充填用複合材 |
US4911691A (en) * | 1984-09-21 | 1990-03-27 | Menlo Care, Inc. | Assembly for adminstering IV solution |
US4883699A (en) * | 1984-09-21 | 1989-11-28 | Menlo Care, Inc. | Polymeric article having high tensile energy to break when hydrated |
US4592755A (en) * | 1985-06-11 | 1986-06-03 | Ethyl Corporation | Mammary implant |
US4798876A (en) * | 1985-11-12 | 1989-01-17 | Tyndale Plains-Hunter Ltd. | Hydrophilic polyurethane composition |
US4880622A (en) * | 1986-05-20 | 1989-11-14 | Research Corporation Technologies, Inc. | Water-soluble phosphazene polymers having pharmacological applications |
US5634946A (en) * | 1988-08-24 | 1997-06-03 | Focal, Inc. | Polymeric endoluminal paving process |
US4975280A (en) * | 1989-01-23 | 1990-12-04 | Ethyl Corporation | Bioerodable sustained release implants |
US5439446A (en) * | 1994-06-30 | 1995-08-08 | Boston Scientific Corporation | Stent and therapeutic delivery system |
FR2679466B1 (fr) * | 1991-07-25 | 1994-04-15 | Ceramique Technique | Membrane de filtration et procede de fabrication. |
DE4138513A1 (de) * | 1991-11-23 | 1993-05-27 | Basf Ag | Feste pharmazeutische retardform |
US5464650A (en) * | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
ES2290074T3 (es) * | 1993-07-19 | 2008-02-16 | Angiotech Pharmaceuticals, Inc. | Composiciones anti-angiogenicas que contienen taxol y un vehiculo no biodegradable y su uso. |
US5716981A (en) * | 1993-07-19 | 1998-02-10 | Angiogenesis Technologies, Inc. | Anti-angiogenic compositions and methods of use |
WO1995028124A2 (en) * | 1994-04-08 | 1995-10-26 | Atrix Laboratories, Inc. | An adjunctive polymer system for use with medical device |
US5788979A (en) * | 1994-07-22 | 1998-08-04 | Inflow Dynamics Inc. | Biodegradable coating with inhibitory properties for application to biocompatible materials |
US5548060A (en) * | 1994-08-08 | 1996-08-20 | Penn State Research Foundation, Inc. | Sulfonation of polyphosphazenes |
US5605696A (en) * | 1995-03-30 | 1997-02-25 | Advanced Cardiovascular Systems, Inc. | Drug loaded polymeric material and method of manufacture |
DE19613048C2 (de) * | 1995-03-30 | 1997-12-18 | Michael Prof Dr Grunze | Künstliche Implantate mit antithrombogenen Eigenschaften und Verfahren zu deren Herstellung |
US5914388A (en) * | 1995-04-26 | 1999-06-22 | The Penn State Research Foundation | Synthesis polyphosphazenes with controlled molecular weight and polydisperity |
US5603722A (en) * | 1995-06-06 | 1997-02-18 | Quanam Medical Corporation | Intravascular stent |
CA2178541C (en) * | 1995-06-07 | 2009-11-24 | Neal E. Fearnot | Implantable medical device |
US6007573A (en) * | 1996-09-18 | 1999-12-28 | Microtherapeutics, Inc. | Intracranial stent and method of use |
US6254628B1 (en) * | 1996-12-09 | 2001-07-03 | Micro Therapeutics, Inc. | Intracranial stent |
US5707597A (en) * | 1996-11-13 | 1998-01-13 | Virus Research Institute, Inc. | Polyhalophosphazene solutions stable against gelation |
US5980972A (en) * | 1996-12-20 | 1999-11-09 | Schneider (Usa) Inc | Method of applying drug-release coatings |
US5814704A (en) * | 1997-03-04 | 1998-09-29 | Virus Research Institute, Inc. | Recovery of polyphosphazene polyacids or acids salts thereof |
US5843172A (en) * | 1997-04-15 | 1998-12-01 | Advanced Cardiovascular Systems, Inc. | Porous medicated stent |
US6273913B1 (en) * | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
US6077916A (en) * | 1997-06-04 | 2000-06-20 | The Penn State Research Foundation | Biodegradable mixtures of polyphoshazene and other polymers |
DE19744135C1 (de) * | 1997-09-29 | 1999-03-25 | Schering Ag | Beschichtete medizinische Implantate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Restenoseprophylaxe |
DE19743373A1 (de) * | 1997-09-30 | 1999-04-15 | Univ Heidelberg | ·3··2·P-Polyphosphazen |
US6485514B1 (en) * | 1997-12-12 | 2002-11-26 | Supergen, Inc. | Local delivery of therapeutic agents |
US20010029351A1 (en) * | 1998-04-16 | 2001-10-11 | Robert Falotico | Drug combinations and delivery devices for the prevention and treatment of vascular disease |
JP4583597B2 (ja) * | 1998-05-05 | 2010-11-17 | ボストン サイエンティフィック リミテッド | 末端が滑らかなステント |
US6254634B1 (en) * | 1998-06-10 | 2001-07-03 | Surmodics, Inc. | Coating compositions |
US5997301A (en) * | 1998-10-20 | 1999-12-07 | Linden; Lars Ake | Treatment of tooth surfaces and substances therefor |
US6958147B1 (en) * | 1998-10-26 | 2005-10-25 | Licentia Ltd | Use of VEGF-C to prevent restenosis |
US6258121B1 (en) * | 1999-07-02 | 2001-07-10 | Scimed Life Systems, Inc. | Stent coating |
US6790228B2 (en) * | 1999-12-23 | 2004-09-14 | Advanced Cardiovascular Systems, Inc. | Coating for implantable devices and a method of forming the same |
US6503556B2 (en) * | 2000-12-28 | 2003-01-07 | Advanced Cardiovascular Systems, Inc. | Methods of forming a coating for a prosthesis |
US6203551B1 (en) * | 1999-10-04 | 2001-03-20 | Advanced Cardiovascular Systems, Inc. | Chamber for applying therapeutic substances to an implant device |
KR100315630B1 (ko) * | 1999-11-17 | 2001-12-12 | 박호군 | 온도변화에 따라 상전이 거동을 갖는 분해성폴리포스파젠계 고분자 및 그 제조방법 |
CA2402949C (en) * | 2000-03-18 | 2009-09-08 | Polyzenix Gmbh | Polyphosphazene derivatives having bacterial resistance and use thereof |
WO2001080919A2 (de) * | 2000-04-11 | 2001-11-01 | Polyzenix Gmbh | Umhüllungen und folien aus poly-tri-fluor-ethoxypolyphosphazen |
US20020005206A1 (en) * | 2000-05-19 | 2002-01-17 | Robert Falotico | Antiproliferative drug and delivery device |
US6689807B1 (en) * | 2000-06-08 | 2004-02-10 | Caritas St. Elizabeth's Medical Center Of Boston, Inc. | HMG CoA reductase inhibitors for promoting angiogenesis |
US20020111590A1 (en) * | 2000-09-29 | 2002-08-15 | Davila Luis A. | Medical devices, drug coatings and methods for maintaining the drug coatings thereon |
US6863685B2 (en) * | 2001-03-29 | 2005-03-08 | Cordis Corporation | Radiopacity intraluminal medical device |
US6746773B2 (en) * | 2000-09-29 | 2004-06-08 | Ethicon, Inc. | Coatings for medical devices |
US8303609B2 (en) * | 2000-09-29 | 2012-11-06 | Cordis Corporation | Coated medical devices |
US7261735B2 (en) * | 2001-05-07 | 2007-08-28 | Cordis Corporation | Local drug delivery devices and methods for maintaining the drug coatings thereon |
AU2002340749A1 (en) * | 2001-05-04 | 2002-11-18 | Concentric Medical | Coated combination vaso-occlusive device |
US7195640B2 (en) * | 2001-09-25 | 2007-03-27 | Cordis Corporation | Coated medical devices for the treatment of vulnerable plaque |
US20030065377A1 (en) * | 2001-09-28 | 2003-04-03 | Davila Luis A. | Coated medical devices |
US20030065345A1 (en) * | 2001-09-28 | 2003-04-03 | Kevin Weadock | Anastomosis devices and methods for treating anastomotic sites |
US6887270B2 (en) * | 2002-02-08 | 2005-05-03 | Boston Scientific Scimed, Inc. | Implantable or insertable medical device resistant to microbial growth and biofilm formation |
-
2000
- 2000-08-11 EP EP00117191A patent/EP1179353A1/de not_active Withdrawn
-
2001
- 2001-08-01 JP JP2002519020A patent/JP4886156B2/ja not_active Expired - Lifetime
- 2001-08-01 US US10/344,216 patent/US20030157142A1/en not_active Abandoned
- 2001-08-01 BR BRPI0113184-2A patent/BR0113184B1/pt not_active IP Right Cessation
- 2001-08-01 CN CNB018173063A patent/CN100467073C/zh not_active Expired - Lifetime
- 2001-08-01 KR KR1020037001952A patent/KR100809134B1/ko not_active IP Right Cessation
- 2001-08-01 AU AU9544701A patent/AU9544701A/xx active Pending
- 2001-08-01 AU AU2001295447A patent/AU2001295447B2/en not_active Expired
- 2001-08-01 EP EP01976054A patent/EP1337285B1/de not_active Expired - Lifetime
- 2001-08-01 WO PCT/EP2001/008913 patent/WO2002013882A1/de active IP Right Grant
- 2001-08-01 DK DK01976054T patent/DK1337285T3/da active
- 2001-08-01 CA CA2424359A patent/CA2424359C/en not_active Expired - Lifetime
- 2001-08-01 AT AT01976054T patent/ATE374626T1/de active
- 2001-08-01 DE DE50113094T patent/DE50113094D1/de not_active Expired - Lifetime
- 2001-08-01 ES ES01976054T patent/ES2296811T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR100809134B1 (ko) | 2008-02-29 |
CA2424359A1 (en) | 2003-02-06 |
US20030157142A1 (en) | 2003-08-21 |
AU2001295447B2 (en) | 2007-01-04 |
BR0113184B1 (pt) | 2014-12-02 |
ATE374626T1 (de) | 2007-10-15 |
AU9544701A (en) | 2002-02-25 |
WO2002013882A1 (de) | 2002-02-21 |
ES2296811T3 (es) | 2008-05-01 |
JP2004522461A (ja) | 2004-07-29 |
EP1179353A1 (de) | 2002-02-13 |
DE50113094D1 (de) | 2007-11-15 |
CA2424359C (en) | 2012-03-20 |
CN1469759A (zh) | 2004-01-21 |
CN100467073C (zh) | 2009-03-11 |
JP4886156B2 (ja) | 2012-02-29 |
KR20030061780A (ko) | 2003-07-22 |
DK1337285T3 (da) | 2008-02-11 |
EP1337285A1 (de) | 2003-08-27 |
EP1337285B1 (de) | 2007-10-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0113184A (pt) | Implante artificial e processo para produzir o mesmo | |
ATE300306T1 (de) | Pharmazeutische zusammensetzung zur ophtalmologischen und rhinologischen anwendung | |
BRPI0414843A (pt) | revestimentos de ácido hialurÈnico antimicrobiais para implantes ortopédicos | |
BR0011448A (pt) | Imidazoquinolinas substituìdas por amida | |
DOP2002000429A (es) | Imidazotriazinas | |
CA2407439A1 (en) | Individual venous valve prosthesis | |
ECSP034797A (es) | DERIVADOS DIHIDRO-BENZO[b][1,4]DIAZEPIN-2-ONA COMO ANTAGONISTAS II MGLUR2 | |
ATE431113T1 (de) | Gelenk- und zahnimplantate | |
BR0116452A (pt) | Composto, composição farmacêutica, uso de um composto | |
EP3238665A3 (en) | Diffusion-hardened medical implant | |
GT200100152A (es) | Nueva composicion farmaceutica para el tratamiento de la obesidad. | |
BR0315090A (pt) | Processo para fazer um produto polimérico, disco espinal artificial, implante cirúrgico, aparelho para fazer um produto polimérico, e, utilização do processo | |
DE60202461D1 (de) | Kalziumphosphat / -sulfat-basierte knochenimplantat zusammensetzung | |
DE59805647D1 (de) | Implantat aus resorbierbaren phosphatglas | |
AU2001283781A1 (en) | Method for producing bioactive implant surfaces | |
HK1081866A1 (en) | Use of hesperidin or one of its derivatives for making a medicine for bone formation stimulation | |
BR0209327A (pt) | Composição para tratamento de constipação induzida por drogas | |
ATE359279T1 (de) | Moschus-geruchsstoffe | |
ATE291424T1 (de) | Katechin und quercetin zur pharmazeutischen oder diätetischen verwendung | |
GB0623258D0 (en) | Thiadiazole derivatives for the treatment of neuro-degenerative diseases | |
ITPD20000218A0 (it) | Impianto perfezionato per il fissaggio di protesi dentarie. | |
SV2002000227A (es) | 2-(3,5-bis-trifluorometil-fenil)-n-metil-n-(6-morfolin-4-il-4-o-tolil-piridin-3-il)-isobutiramida caso 20502 | |
AR021843A1 (es) | Derivados de propanolamina sustituidos con heterociclos, procedimiento para su preparacion, y su utilizacion. | |
BR0016524A (pt) | Suspensão compreendendo oxcarbazepina | |
ATE281432T1 (de) | C-16 ungesätigte fp-selektive prostaglandin analoge |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 02/12/2014, OBSERVADAS AS CONDICOES LEGAIS. |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 17A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2473 DE 29-05-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |