DK1330453T3 - Indolylpiperidinderivater som antihistamin- og anti-allergimidler - Google Patents
Indolylpiperidinderivater som antihistamin- og anti-allergimidlerInfo
- Publication number
- DK1330453T3 DK1330453T3 DK01992709T DK01992709T DK1330453T3 DK 1330453 T3 DK1330453 T3 DK 1330453T3 DK 01992709 T DK01992709 T DK 01992709T DK 01992709 T DK01992709 T DK 01992709T DK 1330453 T3 DK1330453 T3 DK 1330453T3
- Authority
- DK
- Denmark
- Prior art keywords
- antihistamine
- allergy agents
- indolylpiperidine derivatives
- indolylpiperidine
- derivatives
- Prior art date
Links
- HNQZRUDJRPSFAU-UHFFFAOYSA-N 2-piperidin-1-yl-1h-indole Chemical class C1CCCCN1C1=CC2=CC=CC=C2N1 HNQZRUDJRPSFAU-UHFFFAOYSA-N 0.000 title 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title 1
- 230000001387 anti-histamine Effects 0.000 title 1
- 239000000043 antiallergic agent Substances 0.000 title 1
- 239000000739 antihistaminic agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200002615A ES2172436B1 (es) | 2000-10-31 | 2000-10-31 | Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1330453T3 true DK1330453T3 (da) | 2006-08-07 |
Family
ID=8495472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01992709T DK1330453T3 (da) | 2000-10-31 | 2001-10-26 | Indolylpiperidinderivater som antihistamin- og anti-allergimidler |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7189741B2 (enExample) |
| EP (1) | EP1330453B1 (enExample) |
| JP (1) | JP4184785B2 (enExample) |
| AR (1) | AR031168A1 (enExample) |
| AT (1) | ATE321761T1 (enExample) |
| AU (1) | AU2002223655A1 (enExample) |
| CA (1) | CA2427589A1 (enExample) |
| DE (1) | DE60118434T2 (enExample) |
| DK (1) | DK1330453T3 (enExample) |
| ES (2) | ES2172436B1 (enExample) |
| MY (1) | MY155914A (enExample) |
| PE (1) | PE20020543A1 (enExample) |
| PT (1) | PT1330453E (enExample) |
| SI (1) | SI1330453T1 (enExample) |
| UY (1) | UY27001A1 (enExample) |
| WO (1) | WO2002036589A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2201899B1 (es) | 2002-04-01 | 2005-06-01 | Almirall Prodesfarma, S.A. | Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos. |
| ES2201907B1 (es) * | 2002-05-29 | 2005-06-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos. |
| DE60309598T2 (de) * | 2002-06-24 | 2007-09-13 | Schering Corp. | Als histamin-h3-antagonisten geeignete indolderivate |
| AU2003297597A1 (en) * | 2002-11-26 | 2004-06-18 | Isis Pharmaceuticals, Inc. | Benzimidazoles and analogs thereof as antibacterials |
| JP2009515833A (ja) * | 2005-10-24 | 2009-04-16 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ３−ピペリジン−４−イル−インドールｏｒｌ−１受容体モジュレーター |
| WO2008049874A1 (en) * | 2006-10-27 | 2008-05-02 | Boehringer Ingelheim International Gmbh | Piperidyl-propane-thiol ccr3 modulators |
| DK2137162T3 (en) * | 2007-03-15 | 2018-11-26 | Novartis Ag | Organic compounds and their applications |
| US20100041663A1 (en) | 2008-07-18 | 2010-02-18 | Novartis Ag | Organic Compounds as Smo Inhibitors |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK471479A (da) | 1978-12-13 | 1980-06-14 | Pfizer | Fremgangsmaade til fremstilling af imidazolderivater og salte deraf |
| US4742057A (en) * | 1985-12-05 | 1988-05-03 | Fujisawa Pharmaceutical Co., Ltd. | Antiallergic thiazole compounds |
| US4843068A (en) | 1985-12-27 | 1989-06-27 | Nihon Nohyaku Co., Ltd. | Pyrazole oxime derivatives and compositions |
| DK733788A (da) | 1988-01-14 | 1989-07-15 | Fujisawa Pharmaceutical Co | Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf |
| ES2163407T3 (es) * | 1992-02-13 | 2002-02-01 | Merrell Pharma Inc | Derivados piperidinilos tiaciclicos. |
| JP3338913B2 (ja) * | 1993-06-29 | 2002-10-28 | 大鵬薬品工業株式会社 | テトラゾール誘導体 |
| IT1271417B (it) | 1993-10-15 | 1997-05-28 | Erregierre Ind Chim | Composti ad attivita' antiistaminica procedimento per la loro preperazione e composizioni farmaceutiche che li contengono. |
| DE19500689A1 (de) | 1995-01-12 | 1996-07-18 | Merck Patent Gmbh | Indolpiperidin-Derivate |
| DE19707628A1 (de) | 1997-02-26 | 1998-08-27 | Merck Patent Gmbh | Oxazolidinone |
| AR013669A1 (es) | 1997-10-07 | 2001-01-10 | Smithkline Beecham Corp | Compuestos y metodos |
| ES2165274B1 (es) * | 1999-06-04 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos. |
| AR028685A1 (es) | 2000-06-14 | 2003-05-21 | Lundbeck & Co As H | Derivados de indol |
-
2000
- 2000-10-31 ES ES200002615A patent/ES2172436B1/es not_active Expired - Fee Related
-
2001
- 2001-10-26 EP EP01992709A patent/EP1330453B1/en not_active Expired - Lifetime
- 2001-10-26 AT AT01992709T patent/ATE321761T1/de not_active IP Right Cessation
- 2001-10-26 AU AU2002223655A patent/AU2002223655A1/en not_active Abandoned
- 2001-10-26 JP JP2002539348A patent/JP4184785B2/ja not_active Expired - Fee Related
- 2001-10-26 SI SI200130521T patent/SI1330453T1/sl unknown
- 2001-10-26 DE DE60118434T patent/DE60118434T2/de not_active Expired - Lifetime
- 2001-10-26 CA CA002427589A patent/CA2427589A1/en not_active Abandoned
- 2001-10-26 ES ES01992709T patent/ES2259052T3/es not_active Expired - Lifetime
- 2001-10-26 PT PT01992709T patent/PT1330453E/pt unknown
- 2001-10-26 WO PCT/EP2001/012450 patent/WO2002036589A1/en not_active Ceased
- 2001-10-26 DK DK01992709T patent/DK1330453T3/da active
- 2001-10-26 US US10/415,693 patent/US7189741B2/en not_active Expired - Fee Related
- 2001-10-30 AR ARP010105068A patent/AR031168A1/es not_active Application Discontinuation
- 2001-10-30 PE PE2001001079A patent/PE20020543A1/es not_active Application Discontinuation
- 2001-10-30 MY MYPI20015021A patent/MY155914A/en unknown
- 2001-10-31 UY UY27001A patent/UY27001A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20040116471A1 (en) | 2004-06-17 |
| CA2427589A1 (en) | 2002-05-10 |
| US7189741B2 (en) | 2007-03-13 |
| AU2002223655A1 (en) | 2002-05-15 |
| AR031168A1 (es) | 2003-09-10 |
| PE20020543A1 (es) | 2002-07-17 |
| EP1330453A1 (en) | 2003-07-30 |
| DE60118434T2 (de) | 2006-12-14 |
| JP4184785B2 (ja) | 2008-11-19 |
| PT1330453E (pt) | 2006-07-31 |
| EP1330453B1 (en) | 2006-03-29 |
| UY27001A1 (es) | 2001-12-28 |
| JP2004513127A (ja) | 2004-04-30 |
| ES2259052T3 (es) | 2006-09-16 |
| SI1330453T1 (sl) | 2006-08-31 |
| ES2172436A1 (es) | 2002-09-16 |
| MY155914A (en) | 2015-12-15 |
| ATE321761T1 (de) | 2006-04-15 |
| ES2172436B1 (es) | 2004-01-16 |
| DE60118434D1 (de) | 2006-05-18 |
| WO2002036589A1 (en) | 2002-05-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1292604T3 (da) | 2-Aminocarbonyl-9H-purinderivater | |
| NO20023828L (no) | Pyrimidin-4-on derivater som LDL-PLA2 inhibitorer | |
| DK1183251T3 (da) | Indolylpiperidinderivater som antihistamin- og antiallergimidler | |
| ATE391531T1 (de) | Schweisshemmende mittel | |
| NO20021329L (no) | Kinaseinhibitorer som terapeutiske midler | |
| ATE540013T1 (de) | Naphthalinderivate | |
| ATE288437T1 (de) | Tetrahydro-heterocycloazepinyl-pyrimidin-deriva e | |
| DK1280809T3 (da) | Antitumorecteinascidinderivater | |
| NO20025150D0 (no) | 2-acylindolderivater og deres anvendelse som antitumormidler | |
| ATE298332T1 (de) | Decahydro-isochinolinderivate | |
| NO20023770L (no) | Indol-3-ylderivater | |
| NO20030276L (no) | Fremgangsmåte | |
| ATE414056T1 (de) | Substituierte c-cyclohexylmethylamin-derivative | |
| NO20021959L (no) | Tetrahydrotiopyranftalazinon-derivater som PDE4-inhibitorer | |
| DK1216250T3 (da) | Thienoisoxazolyl- og thienylpyrazolyl-phenoxy- substituerede propylderivater som D4-antagonister | |
| ATE282021T1 (de) | Substituierte aminomethyl-phenyl- cyclohexanderivate | |
| DK1322593T3 (da) | O-substituerede-6-methyl-tramadol-derivater | |
| DK1330453T3 (da) | Indolylpiperidinderivater som antihistamin- og anti-allergimidler | |
| PT1339695E (pt) | Inibidores da farnesiltransferase | |
| FI20000194A0 (fi) | Menetelmä kaupankäynnissä | |
| ATE280752T1 (de) | Aminomethyl-phenyl-cyclohexanonderivate | |
| DK1259515T3 (da) | Thienopyridinderivater og deres anvendelse som antiinflammatoriske midler | |
| DE60117096D1 (de) | Dihydroindol- und tetrahydrochinolinderivate | |
| DE50112454D1 (de) | Substituierte 5-amino-1-penten-3-ol-derivate | |
| DE60118970D1 (de) | Indol- und dihydroindolderivate |