DK131633C - Fremgangsmade til fremstilling af 3-(17beta-4-androsten-3-on-17beta-yl)-propiolacton - Google Patents

Fremgangsmade til fremstilling af 3-(17beta-4-androsten-3-on-17beta-yl)-propiolacton

Info

Publication number
DK131633C
DK131633C DK262774A DK262774A DK131633C DK 131633 C DK131633 C DK 131633C DK 262774 A DK262774 A DK 262774A DK 262774 A DK262774 A DK 262774A DK 131633 C DK131633 C DK 131633C
Authority
DK
Denmark
Prior art keywords
17beta
androsten
propiolactone
preparing
procedure
Prior art date
Application number
DK262774A
Other languages
English (en)
Other versions
DK131633B (da
DK262774A (da
Inventor
R Philippson
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732327448 external-priority patent/DE2327448C3/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK262774A publication Critical patent/DK262774A/da
Publication of DK131633B publication Critical patent/DK131633B/da
Application granted granted Critical
Publication of DK131633C publication Critical patent/DK131633C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001—Lactones
    • C07J21/003—Lactones at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DK262774A 1973-05-25 1974-05-14 Fremgangsmade til fremstilling af 3-(17beta-4-androsten-3-on-17beta-yl)-propiolacton DK131633C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732327448 DE2327448C3 (de) 1973-05-25 Verfahren zur Herstellung von 17alpha-(3-Hydroxypropyl)-17beta-hydroxy-3-keto -4-a nd roste n

Publications (3)

Publication Number Publication Date
DK262774A DK262774A (da) 1975-01-20
DK131633B DK131633B (da) 1975-08-11
DK131633C true DK131633C (da) 1976-01-12

Family

ID=5882517

Family Applications (1)

Application Number Title Priority Date Filing Date
DK262774A DK131633C (da) 1973-05-25 1974-05-14 Fremgangsmade til fremstilling af 3-(17beta-4-androsten-3-on-17beta-yl)-propiolacton

Country Status (19)

Country Link
US (1) US3966714A (da)
JP (1) JPS5821640B2 (da)
AT (1) AT351179B (da)
BE (1) BE815493A (da)
CA (1) CA1013342A (da)
CH (1) CH609357A5 (da)
CS (1) CS169769B2 (da)
DD (1) DD113353A5 (da)
DK (1) DK131633C (da)
ES (1) ES426419A1 (da)
FR (1) FR2230630B1 (da)
GB (1) GB1472300A (da)
HU (1) HU166779B (da)
IE (1) IE39279B1 (da)
IL (1) IL44886A (da)
NL (1) NL184221C (da)
SE (1) SE401187B (da)
SU (1) SU633486A3 (da)
YU (1) YU36385B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE44711B1 (en) * 1976-03-05 1982-03-10 Schering Ag 17 -hydroxypropyl-4-3-keto-steroids and esters thereof, and process for their manufacture
ES469510A1 (es) * 1977-05-16 1978-12-01 Schering Ag Procedimiento para la preparacion de 17beta hidroxi-4-an- drosten-3-onas.
DE3026783C2 (de) * 1980-07-11 1982-07-29 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 5β-Hydroxy-δ↑6↑-steroiden
US4501695A (en) * 1983-05-16 1985-02-26 The Upjohn Company Spironalactone process
DE3414508A1 (de) * 1984-04-13 1985-10-24 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrfach tritiierte steroid-20.17-spirolactone und ihre verwendung als tracersubstanzen
CN104327149B (zh) * 2014-09-11 2017-01-11 浙江神洲药业有限公司 一种螺内酯中间体睾丸素内酯的合成方法
CN104327150B (zh) * 2014-09-11 2016-08-24 浙江神洲药业有限公司 一种螺内酯中间体坎利酮的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1171543A (fr) * 1956-03-10 1959-01-27 Schering Ag Procédé d'éthinylation de 17-céto-stéroïdes
US3325484A (en) * 1963-11-15 1967-06-13 American Home Prod Process for preparing periplogenia and intermediates secured therein
US3356677A (en) * 1966-04-05 1967-12-05 Syntex Corp 1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes
US3462426A (en) * 1967-10-30 1969-08-19 Searle & Co 3 - (3 - oxo - 11beta,13beta-dialkyl-17beta-hydroxygonen - 17alpha - yl) propionic acid gamma-lactones and intermediates
US3455909A (en) * 1968-05-29 1969-07-15 American Home Prod 3-desoxy steroidal-1,4-diene lactones and spiroethers
US3753979A (en) * 1971-12-06 1973-08-21 Merck & Co Inc Substituted 1,2alpha-methylene-6,7alpha-halomethylene-20-spirox-4-en-3-ones or 3-ols and acyl esters thereof

Also Published As

Publication number Publication date
ATA420974A (de) 1978-12-15
HU166779B (da) 1975-05-28
DK131633B (da) 1975-08-11
GB1472300A (en) 1977-05-04
CA1013342A (en) 1977-07-05
DE2327448B2 (de) 1976-04-29
NL7406978A (da) 1974-11-27
YU36385B (en) 1983-06-30
CH609357A5 (da) 1979-02-28
IL44886A0 (en) 1974-09-10
YU129274A (en) 1981-11-13
CS169769B2 (da) 1976-07-29
DK262774A (da) 1975-01-20
FR2230630B1 (da) 1977-10-14
US3966714A (en) 1976-06-29
IE39279B1 (en) 1978-09-13
SE401187B (sv) 1978-04-24
AT351179B (de) 1979-07-10
JPS5030861A (da) 1975-03-27
IE39279L (en) 1974-11-25
DD113353A5 (da) 1975-06-05
IL44886A (en) 1977-10-31
FR2230630A1 (da) 1974-12-20
JPS5821640B2 (ja) 1983-05-02
BE815493A (fr) 1974-11-25
AU6914874A (en) 1975-11-20
DE2327448A1 (de) 1974-12-12
NL184221C (nl) 1989-05-16
ES426419A1 (es) 1976-07-01
SU633486A3 (ru) 1978-11-15

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Legal Events

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PBP Patent lapsed