SE401187B - Sett att framstella deltaŸ4-3-ketosteroid-17-propiolakton - Google Patents

Sett att framstella deltaŸ4-3-ketosteroid-17-propiolakton

Info

Publication number
SE401187B
SE401187B SE7406779A SE7406779A SE401187B SE 401187 B SE401187 B SE 401187B SE 7406779 A SE7406779 A SE 7406779A SE 7406779 A SE7406779 A SE 7406779A SE 401187 B SE401187 B SE 401187B
Authority
SE
Sweden
Prior art keywords
deltaÿ4
propiolacton
ketosteroid
preparing
preparing deltaÿ4
Prior art date
Application number
SE7406779A
Other languages
English (en)
Inventor
R Philippson
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732327448 external-priority patent/DE2327448C3/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of SE401187B publication Critical patent/SE401187B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused
    • C07J53/0043 membered carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
SE7406779A 1973-05-25 1974-05-21 Sett att framstella deltaŸ4-3-ketosteroid-17-propiolakton SE401187B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732327448 DE2327448C3 (de) 1973-05-25 Verfahren zur Herstellung von 17alpha-(3-Hydroxypropyl)-17beta-hydroxy-3-keto -4-a nd roste n

Publications (1)

Publication Number Publication Date
SE401187B true SE401187B (sv) 1978-04-24

Family

ID=5882517

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7406779A SE401187B (sv) 1973-05-25 1974-05-21 Sett att framstella deltaŸ4-3-ketosteroid-17-propiolakton

Country Status (19)

Country Link
US (1) US3966714A (sv)
JP (1) JPS5821640B2 (sv)
AT (1) AT351179B (sv)
BE (1) BE815493A (sv)
CA (1) CA1013342A (sv)
CH (1) CH609357A5 (sv)
CS (1) CS169769B2 (sv)
DD (1) DD113353A5 (sv)
DK (1) DK131633C (sv)
ES (1) ES426419A1 (sv)
FR (1) FR2230630B1 (sv)
GB (1) GB1472300A (sv)
HU (1) HU166779B (sv)
IE (1) IE39279B1 (sv)
IL (1) IL44886A (sv)
NL (1) NL184221C (sv)
SE (1) SE401187B (sv)
SU (1) SU633486A3 (sv)
YU (1) YU36385B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH631462A5 (de) * 1976-03-05 1982-08-13 Schering Ag Verfahren zur herstellung von neuen steroiden der androstan- oder oestranreihe.
ES469510A1 (es) * 1977-05-16 1978-12-01 Schering Ag Procedimiento para la preparacion de 17beta hidroxi-4-an- drosten-3-onas.
DE3026783C2 (de) * 1980-07-11 1982-07-29 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 5β-Hydroxy-δ↑6↑-steroiden
US4501695A (en) * 1983-05-16 1985-02-26 The Upjohn Company Spironalactone process
DE3414508A1 (de) * 1984-04-13 1985-10-24 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrfach tritiierte steroid-20.17-spirolactone und ihre verwendung als tracersubstanzen
CN104327149B (zh) * 2014-09-11 2017-01-11 浙江神洲药业有限公司 一种螺内酯中间体睾丸素内酯的合成方法
CN104327150B (zh) * 2014-09-11 2016-08-24 浙江神洲药业有限公司 一种螺内酯中间体坎利酮的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1171543A (fr) * 1956-03-10 1959-01-27 Schering Ag Procédé d'éthinylation de 17-céto-stéroïdes
US3325484A (en) * 1963-11-15 1967-06-13 American Home Prod Process for preparing periplogenia and intermediates secured therein
US3356677A (en) * 1966-04-05 1967-12-05 Syntex Corp 1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes
US3462426A (en) * 1967-10-30 1969-08-19 Searle & Co 3 - (3 - oxo - 11beta,13beta-dialkyl-17beta-hydroxygonen - 17alpha - yl) propionic acid gamma-lactones and intermediates
US3455909A (en) * 1968-05-29 1969-07-15 American Home Prod 3-desoxy steroidal-1,4-diene lactones and spiroethers
US3753979A (en) * 1971-12-06 1973-08-21 Merck & Co Inc Substituted 1,2alpha-methylene-6,7alpha-halomethylene-20-spirox-4-en-3-ones or 3-ols and acyl esters thereof

Also Published As

Publication number Publication date
ES426419A1 (es) 1976-07-01
GB1472300A (en) 1977-05-04
ATA420974A (de) 1978-12-15
DK131633B (da) 1975-08-11
BE815493A (fr) 1974-11-25
DD113353A5 (sv) 1975-06-05
DK262774A (sv) 1975-01-20
NL184221C (nl) 1989-05-16
IL44886A (en) 1977-10-31
CS169769B2 (sv) 1976-07-29
DE2327448B2 (de) 1976-04-29
CA1013342A (en) 1977-07-05
AU6914874A (en) 1975-11-20
AT351179B (de) 1979-07-10
YU129274A (en) 1981-11-13
SU633486A3 (ru) 1978-11-15
IL44886A0 (en) 1974-09-10
IE39279L (en) 1974-11-25
FR2230630B1 (sv) 1977-10-14
FR2230630A1 (sv) 1974-12-20
CH609357A5 (sv) 1979-02-28
JPS5821640B2 (ja) 1983-05-02
JPS5030861A (sv) 1975-03-27
HU166779B (sv) 1975-05-28
YU36385B (en) 1983-06-30
DE2327448A1 (de) 1974-12-12
NL7406978A (sv) 1974-11-27
DK131633C (da) 1976-01-12
IE39279B1 (en) 1978-09-13
US3966714A (en) 1976-06-29

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