DK131633B - Fremgangsmåde til fremstilling af 3-(17beta-4-androsten-3-on-17beta-yl)-propiolacton. - Google Patents

Fremgangsmåde til fremstilling af 3-(17beta-4-androsten-3-on-17beta-yl)-propiolacton.

Info

Publication number
DK131633B
DK131633B DK262774AA DK262774A DK131633B DK 131633 B DK131633 B DK 131633B DK 262774A A DK262774A A DK 262774AA DK 262774 A DK262774 A DK 262774A DK 131633 B DK131633 B DK 131633B
Authority
DK
Denmark
Prior art keywords
17beta
androsten
propiolactone
preparation
Prior art date
Application number
DK262774AA
Other languages
English (en)
Other versions
DK262774A (da
DK131633C (da
Inventor
R Philippson
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732327448 external-priority patent/DE2327448C3/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK262774A publication Critical patent/DK262774A/da
Publication of DK131633B publication Critical patent/DK131633B/da
Application granted granted Critical
Publication of DK131633C publication Critical patent/DK131633C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused
    • C07J53/0043 membered carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DK262774A 1973-05-25 1974-05-14 Fremgangsmade til fremstilling af 3-(17beta-4-androsten-3-on-17beta-yl)-propiolacton DK131633C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732327448 DE2327448C3 (de) 1973-05-25 Verfahren zur Herstellung von 17alpha-(3-Hydroxypropyl)-17beta-hydroxy-3-keto -4-a nd roste n

Publications (3)

Publication Number Publication Date
DK262774A DK262774A (da) 1975-01-20
DK131633B true DK131633B (da) 1975-08-11
DK131633C DK131633C (da) 1976-01-12

Family

ID=5882517

Family Applications (1)

Application Number Title Priority Date Filing Date
DK262774A DK131633C (da) 1973-05-25 1974-05-14 Fremgangsmade til fremstilling af 3-(17beta-4-androsten-3-on-17beta-yl)-propiolacton

Country Status (19)

Country Link
US (1) US3966714A (da)
JP (1) JPS5821640B2 (da)
AT (1) AT351179B (da)
BE (1) BE815493A (da)
CA (1) CA1013342A (da)
CH (1) CH609357A5 (da)
CS (1) CS169769B2 (da)
DD (1) DD113353A5 (da)
DK (1) DK131633C (da)
ES (1) ES426419A1 (da)
FR (1) FR2230630B1 (da)
GB (1) GB1472300A (da)
HU (1) HU166779B (da)
IE (1) IE39279B1 (da)
IL (1) IL44886A (da)
NL (1) NL184221C (da)
SE (1) SE401187B (da)
SU (1) SU633486A3 (da)
YU (1) YU36385B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE44711B1 (en) * 1976-03-05 1982-03-10 Schering Ag 17 -hydroxypropyl-4-3-keto-steroids and esters thereof, and process for their manufacture
ES469510A1 (es) * 1977-05-16 1978-12-01 Schering Ag Procedimiento para la preparacion de 17beta hidroxi-4-an- drosten-3-onas.
DE3026783C2 (de) * 1980-07-11 1982-07-29 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 5β-Hydroxy-δ↑6↑-steroiden
US4501695A (en) * 1983-05-16 1985-02-26 The Upjohn Company Spironalactone process
DE3414508A1 (de) * 1984-04-13 1985-10-24 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrfach tritiierte steroid-20.17-spirolactone und ihre verwendung als tracersubstanzen
CN104327150B (zh) * 2014-09-11 2016-08-24 浙江神洲药业有限公司 一种螺内酯中间体坎利酮的合成方法
CN104327149B (zh) * 2014-09-11 2017-01-11 浙江神洲药业有限公司 一种螺内酯中间体睾丸素内酯的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1171543A (fr) * 1956-03-10 1959-01-27 Schering Ag Procédé d'éthinylation de 17-céto-stéroïdes
US3325484A (en) * 1963-11-15 1967-06-13 American Home Prod Process for preparing periplogenia and intermediates secured therein
US3356677A (en) * 1966-04-05 1967-12-05 Syntex Corp 1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes
US3462426A (en) * 1967-10-30 1969-08-19 Searle & Co 3 - (3 - oxo - 11beta,13beta-dialkyl-17beta-hydroxygonen - 17alpha - yl) propionic acid gamma-lactones and intermediates
US3455909A (en) * 1968-05-29 1969-07-15 American Home Prod 3-desoxy steroidal-1,4-diene lactones and spiroethers
US3753979A (en) * 1971-12-06 1973-08-21 Merck & Co Inc Substituted 1,2alpha-methylene-6,7alpha-halomethylene-20-spirox-4-en-3-ones or 3-ols and acyl esters thereof

Also Published As

Publication number Publication date
FR2230630B1 (da) 1977-10-14
FR2230630A1 (da) 1974-12-20
DK262774A (da) 1975-01-20
CH609357A5 (da) 1979-02-28
US3966714A (en) 1976-06-29
AU6914874A (en) 1975-11-20
ATA420974A (de) 1978-12-15
DK131633C (da) 1976-01-12
GB1472300A (en) 1977-05-04
ES426419A1 (es) 1976-07-01
DE2327448B2 (de) 1976-04-29
YU129274A (en) 1981-11-13
HU166779B (da) 1975-05-28
NL184221C (nl) 1989-05-16
CS169769B2 (da) 1976-07-29
IE39279B1 (en) 1978-09-13
SU633486A3 (ru) 1978-11-15
IL44886A (en) 1977-10-31
AT351179B (de) 1979-07-10
JPS5030861A (da) 1975-03-27
YU36385B (en) 1983-06-30
DE2327448A1 (de) 1974-12-12
JPS5821640B2 (ja) 1983-05-02
DD113353A5 (da) 1975-06-05
SE401187B (sv) 1978-04-24
CA1013342A (en) 1977-07-05
IE39279L (en) 1974-11-25
IL44886A0 (en) 1974-09-10
BE815493A (fr) 1974-11-25
NL7406978A (da) 1974-11-27

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Legal Events

Date Code Title Description
PBP Patent lapsed