DK1313462T3 - Anvendelse af asiatisk syre eller asiaticosid til behandling af cancer - Google Patents

Anvendelse af asiatisk syre eller asiaticosid til behandling af cancer

Info

Publication number
DK1313462T3
DK1313462T3 DK01920974T DK01920974T DK1313462T3 DK 1313462 T3 DK1313462 T3 DK 1313462T3 DK 01920974 T DK01920974 T DK 01920974T DK 01920974 T DK01920974 T DK 01920974T DK 1313462 T3 DK1313462 T3 DK 1313462T3
Authority
DK
Denmark
Prior art keywords
asiaticoside
cancer
treatment
asian acid
acid
Prior art date
Application number
DK01920974T
Other languages
Danish (da)
English (en)
Inventor
Se-Kyung Oh
Chokyun Rha
Kadir Azizol Abdul
Lean Teik Ng
Original Assignee
Government Of Malaysia
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Government Of Malaysia, Massachusetts Inst Technology filed Critical Government Of Malaysia
Application granted granted Critical
Publication of DK1313462T3 publication Critical patent/DK1313462T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK01920974T 2000-08-29 2001-02-14 Anvendelse af asiatisk syre eller asiaticosid til behandling af cancer DK1313462T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MYPI20003987A MY138883A (en) 2000-08-29 2000-08-29 Use of asiatic acid for treatment of cencer
PCT/US2001/040103 WO2002017904A1 (en) 2000-08-29 2001-02-14 Use of asiatic acid or asiaticoside for treatment of cancer

Publications (1)

Publication Number Publication Date
DK1313462T3 true DK1313462T3 (da) 2009-03-30

Family

ID=19749475

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01920974T DK1313462T3 (da) 2000-08-29 2001-02-14 Anvendelse af asiatisk syre eller asiaticosid til behandling af cancer

Country Status (9)

Country Link
US (1) US20040097463A1 (cs)
EP (1) EP1313462B1 (cs)
JP (2) JP2004507496A (cs)
AT (1) ATE415962T1 (cs)
AU (1) AU2001247968A1 (cs)
DE (1) DE60136826D1 (cs)
DK (1) DK1313462T3 (cs)
MY (1) MY138883A (cs)
WO (1) WO2002017904A1 (cs)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030144312A1 (en) * 2001-10-30 2003-07-31 Schoenhard Grant L. Inhibitors of ABC drug transporters in multidrug resistant cancer cells
KR100571886B1 (ko) 2004-02-23 2006-04-17 학교법인 영남학원 아시아틱산을 포함하는 피부암 예방 또는 치료용 조성물
JP2007523956A (ja) * 2004-02-25 2007-08-23 ダナ−ファーバー キャンサー インスティテュート インク． 腫瘍細胞増殖を阻害するための方法
WO2006012015A2 (en) * 2004-06-29 2006-02-02 Oregon Health And Science University Methods and compositions for nerve regeneration
US20070010459A1 (en) * 2005-01-14 2007-01-11 Ying Liu Application of asiatic acid and its derivatives to treat pulmonary fibrosis
WO2006081371A2 (en) * 2005-01-27 2006-08-03 Research Development Foundation Combination therapy with triterpenoid compounds and proteasome inhibitors
WO2009089365A2 (en) 2008-01-11 2009-07-16 Shanghai Institute Of Pharmaceutical Industry (Sipi) Therapeutic formulations based on asiatic acid and selected salts thereof
ES2566750T3 (es) 2008-04-16 2016-04-15 The Johns Hopkins University Método para determinar el riesgo de recidiva de cáncer de próstata
US8835506B2 (en) 2008-06-05 2014-09-16 Stc.Unm Methods and related compositions for the treatment of cancer
BR112012015130B1 (pt) 2009-12-21 2020-04-07 Pirelli processo para construir pneus, e, instalação para construir pneus para rodas de veículos
EP2582376B1 (en) 2010-06-10 2018-05-23 Indus Biotech Private Limited A method for preparation of highly pure asiaticoside composition from centella asiatica and a method of use thereof
ES2694582T3 (es) * 2011-01-31 2018-12-21 Lucolas-M.D. Ltd. Combinaciones de inhibidores de aromatasa y antioxidantes
US20140194368A1 (en) * 2013-01-04 2014-07-10 Beech Tree Labs, Inc. Method of Treating Cancer by Administration of Low Levels of Heat Shock Protein 70 (HSP70)
WO2014153215A1 (en) 2013-03-14 2014-09-25 University Of Maryland,Baltimore Office Of Technology Transfer Androgen receptor down-regulating agents and uses thereof
HUE052599T2 (hu) * 2013-05-03 2021-05-28 Selecta Biosciences Inc CD4+ szabályozó T-sejtek fokozására szolgáló eljárások és készítmények
SG11201600525XA (en) 2013-08-12 2016-02-26 Tokai Pharmaceuticals Inc Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies
EP3146081B1 (en) 2014-05-19 2020-10-28 The Johns Hopkins University Methods for identifying androgen receptor splice variants in subjects having castration resistant prostate cancer
WO2016033114A1 (en) * 2014-08-25 2016-03-03 The Johns Hopkins University Methods and compositions related to prostate cancer therapeutics
EP3124047A1 (en) * 2015-07-28 2017-02-01 Merz Pharma GmbH & Co. KGaA Pentacyclic triterpenoids for injection lipolysis
CN108057034A (zh) * 2016-11-09 2018-05-22 香港中文大学 柚皮素和积雪草酸组合治疗癌症
WO2019200585A1 (en) * 2018-04-19 2019-10-24 The Chinese University Of Hong Kong Naringenin and asiatic acid combination treatment of cancers
CN109528735B (zh) * 2019-01-30 2021-03-12 中国药科大学 积雪草苷在制备治疗皮肤癌药物中的新用途
CN110200981A (zh) * 2019-06-06 2019-09-06 中国药科大学 五环三萜皂苷的医药用途及其药物组合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB923414A (en) * 1960-04-13 1963-04-10 Laroche Navarron Lab Therapeutic compositions comprising asiatic and arjunolic acids
IT1203515B (it) * 1987-02-26 1989-02-15 Indena Spa Complessi di saponine con fosfolipidi e composizioni farmaceutiche e cosmetiche che li contengono
EP0383171A3 (en) * 1989-02-11 1991-07-24 Hoechst Aktiengesellschaft 2,3,23-trihydroxy-urs-12-ene derivatives for treating cognitive disorders
FR2714598B1 (fr) * 1993-12-30 1996-02-09 Oreal Composition amincissante à deux types de liposomes pour traitement topique, son utilisation.
JPH08133952A (ja) * 1994-11-07 1996-05-28 Shiseido Co Ltd 皮膚外用剤
DE69705238T2 (de) * 1996-11-27 2002-04-18 Dong Kook Pharmaceutical Co Derivate der asiatica-saeure mit einem modifizierten a-ring
IT1288257B1 (it) * 1996-11-29 1998-09-11 Paoli Ambrosi Gianfranco De Composizione per uso cosmetico,farmaceutico o dietetico a base di un aminozucchero e/o di un acido poliidrossilico
FR2763336B1 (fr) * 1997-05-14 1999-08-06 Lvmh Rech Esters de tocopherol et leurs utilisations en cosmetique et pharmacie
BRPI0512040A (pt) * 2004-06-14 2008-02-06 Zoser B Salama composição farmacêutica, método de modificação de receptores de célula de tumor, método de aperfeiçoar seletividade alvo de anticorpos, método de tratar cáncer, kit, uso de prolina

Also Published As

Publication number Publication date
JP2004507496A (ja) 2004-03-11
DE60136826D1 (de) 2009-01-15
EP1313462B1 (en) 2008-12-03
WO2002017904A1 (en) 2002-03-07
AU2001247968A1 (en) 2002-03-13
JP2012092110A (ja) 2012-05-17
JP5421340B2 (ja) 2014-02-19
US20040097463A1 (en) 2004-05-20
MY138883A (en) 2009-08-28
EP1313462A1 (en) 2003-05-28
ATE415962T1 (de) 2008-12-15

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