DK1311518T3 - Fremstilling af N-beskyttede-3-pyrroliden-lactam-substituerede phosphoniumsalte - Google Patents
Fremstilling af N-beskyttede-3-pyrroliden-lactam-substituerede phosphoniumsalteInfo
- Publication number
- DK1311518T3 DK1311518T3 DK01969573T DK01969573T DK1311518T3 DK 1311518 T3 DK1311518 T3 DK 1311518T3 DK 01969573 T DK01969573 T DK 01969573T DK 01969573 T DK01969573 T DK 01969573T DK 1311518 T3 DK1311518 T3 DK 1311518T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyrrolidene
- lactam
- protected
- preparation
- phosphonium salts
- Prior art date
Links
- 150000004714 phosphonium salts Chemical class 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
- C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00117525 | 2000-08-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1311518T3 true DK1311518T3 (da) | 2006-02-13 |
Family
ID=8169526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01969573T DK1311518T3 (da) | 2000-08-14 | 2001-08-06 | Fremstilling af N-beskyttede-3-pyrroliden-lactam-substituerede phosphoniumsalte |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US6828442B2 (es) |
| EP (1) | EP1311518B1 (es) |
| JP (1) | JP3989832B2 (es) |
| KR (1) | KR100698814B1 (es) |
| CN (1) | CN1212327C (es) |
| AT (1) | ATE308549T1 (es) |
| AU (1) | AU2001289789A1 (es) |
| CA (1) | CA2418970C (es) |
| DE (1) | DE60114641T2 (es) |
| DK (1) | DK1311518T3 (es) |
| ES (1) | ES2251508T3 (es) |
| MX (1) | MXPA03001310A (es) |
| WO (1) | WO2002014332A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03001310A (es) * | 2000-08-14 | 2003-06-30 | Basilea Pharmaceutica Ag | Preparacion de sales de fosfonio sustituidas con 3-pirrolidin-lactama n-protegida. |
| JP2002212155A (ja) * | 2001-01-17 | 2002-07-31 | Toray Ind Inc | 光学活性アスパラギンエステル誘導体、光学活性３−アミノピロリジン−２，５−ジオン誘導体および光学活性３−アミノピロリジン誘導体の製造方法 |
| ES2565952T3 (es) | 2009-05-25 | 2016-04-07 | Sandoz Ag | Método para la producción de ceftobiprol medocaril |
| CN111471058A (zh) * | 2019-01-23 | 2020-07-31 | 中国医学科学院药物研究所 | 用于制备头孢吡普类似物的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5804577A (en) * | 1995-09-12 | 1998-09-08 | Hoffmann-La Roche Inc. | Cephalosporin derivatives |
| TW415949B (en) * | 1996-12-19 | 2000-12-21 | Hoffmann La Roche | Vinyl pyrrolidine cephalosporin derivatives with basic substituents |
| MXPA03001310A (es) * | 2000-08-14 | 2003-06-30 | Basilea Pharmaceutica Ag | Preparacion de sales de fosfonio sustituidas con 3-pirrolidin-lactama n-protegida. |
-
2001
- 2001-08-06 MX MXPA03001310A patent/MXPA03001310A/es active IP Right Grant
- 2001-08-06 WO PCT/EP2001/009059 patent/WO2002014332A1/en active IP Right Grant
- 2001-08-06 KR KR1020037002100A patent/KR100698814B1/ko not_active IP Right Cessation
- 2001-08-06 CN CNB018141692A patent/CN1212327C/zh not_active Expired - Fee Related
- 2001-08-06 AU AU2001289789A patent/AU2001289789A1/en not_active Abandoned
- 2001-08-06 US US10/344,903 patent/US6828442B2/en not_active Expired - Fee Related
- 2001-08-06 EP EP01969573A patent/EP1311518B1/en not_active Expired - Lifetime
- 2001-08-06 AT AT01969573T patent/ATE308549T1/de active
- 2001-08-06 DK DK01969573T patent/DK1311518T3/da active
- 2001-08-06 CA CA2418970A patent/CA2418970C/en not_active Expired - Fee Related
- 2001-08-06 JP JP2002519470A patent/JP3989832B2/ja not_active Expired - Fee Related
- 2001-08-06 ES ES01969573T patent/ES2251508T3/es not_active Expired - Lifetime
- 2001-08-06 DE DE60114641T patent/DE60114641T2/de not_active Expired - Lifetime
-
2004
- 2004-08-12 US US10/916,954 patent/US7262307B2/en not_active Expired - Fee Related
-
2007
- 2007-07-26 US US11/881,487 patent/US7511154B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1311518A1 (en) | 2003-05-21 |
| JP2004506642A (ja) | 2004-03-04 |
| CA2418970A1 (en) | 2002-02-21 |
| CN1212327C (zh) | 2005-07-27 |
| DE60114641T2 (de) | 2006-07-20 |
| KR100698814B1 (ko) | 2007-03-23 |
| US7262307B2 (en) | 2007-08-28 |
| ES2251508T3 (es) | 2006-05-01 |
| JP3989832B2 (ja) | 2007-10-10 |
| US20050070722A1 (en) | 2005-03-31 |
| US7511154B2 (en) | 2009-03-31 |
| WO2002014332A1 (en) | 2002-02-21 |
| CA2418970C (en) | 2011-03-22 |
| CN1451012A (zh) | 2003-10-22 |
| US20080009637A1 (en) | 2008-01-10 |
| MXPA03001310A (es) | 2003-06-30 |
| DE60114641D1 (de) | 2005-12-08 |
| KR20030022395A (ko) | 2003-03-15 |
| EP1311518B1 (en) | 2005-11-02 |
| AU2001289789A1 (en) | 2002-02-25 |
| US6828442B2 (en) | 2004-12-07 |
| ATE308549T1 (de) | 2005-11-15 |
| US20030195364A1 (en) | 2003-10-16 |
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