PT1255745E - Sintese de derivados de agua soluvel 9-dihidro-paclitaxelo de 9-dihidro-13-acetilobacatina iii - Google Patents

Sintese de derivados de agua soluvel 9-dihidro-paclitaxelo de 9-dihidro-13-acetilobacatina iii

Info

Publication number
PT1255745E
PT1255745E PT01921710T PT01921710T PT1255745E PT 1255745 E PT1255745 E PT 1255745E PT 01921710 T PT01921710 T PT 01921710T PT 01921710 T PT01921710 T PT 01921710T PT 1255745 E PT1255745 E PT 1255745E
Authority
PT
Portugal
Prior art keywords
dihydro
paclitaxelo
acetylobacatin
soluable
synthesis
Prior art date
Application number
PT01921710T
Other languages
English (en)
Inventor
Jian Liu
Original Assignee
Ivax Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Research Inc filed Critical Ivax Research Inc
Publication of PT1255745E publication Critical patent/PT1255745E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
PT01921710T 2000-01-31 2001-01-31 Sintese de derivados de agua soluvel 9-dihidro-paclitaxelo de 9-dihidro-13-acetilobacatina iii PT1255745E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/494,629 US6175023B1 (en) 2000-01-31 2000-01-31 Synthesis of water soluble 9-dihydro-paclitaxel derivatives from 9-dihydro-13-acetylbaccatin III

Publications (1)

Publication Number Publication Date
PT1255745E true PT1255745E (pt) 2004-04-30

Family

ID=23965272

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01921710T PT1255745E (pt) 2000-01-31 2001-01-31 Sintese de derivados de agua soluvel 9-dihidro-paclitaxelo de 9-dihidro-13-acetilobacatina iii

Country Status (13)

Country Link
US (1) US6175023B1 (pt)
EP (1) EP1255745B1 (pt)
JP (1) JP2003531826A (pt)
KR (1) KR20030009347A (pt)
AT (1) ATE257831T1 (pt)
AU (1) AU784830B2 (pt)
CA (1) CA2398655A1 (pt)
DE (1) DE60101784T2 (pt)
DK (1) DK1255745T3 (pt)
ES (1) ES2214410T3 (pt)
PT (1) PT1255745E (pt)
TR (1) TR200400293T4 (pt)
WO (1) WO2001055126A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE349438T1 (de) * 1999-11-24 2007-01-15 Immunogen Inc Cytotoxische wirkstoffe enthaltend taxane und deren therapeutische anwendung
US7239669B2 (en) * 2002-04-30 2007-07-03 Fulcrum Microsystems, Inc. Asynchronous system-on-a-chip interconnect
EP1534674A4 (en) 2002-08-02 2007-11-28 Immunogen Inc CYTOTOXIC AGENTS CONTAINING NEW, EFFECTIVE TAXANES AND THEIR THERAPEUTIC USE
US7390898B2 (en) * 2002-08-02 2008-06-24 Immunogen Inc. Cytotoxic agents containing novel potent taxanes and their therapeutic use
EP1562927B1 (en) * 2002-10-09 2009-05-13 Chatham Biotec Ltd. Thio-analogues of paclitaxel and intermediates thereof
US7202370B2 (en) * 2003-10-27 2007-04-10 Conor Medsystems, Inc. Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
US7771563B2 (en) * 2004-11-18 2010-08-10 Sumitomo Precision Products Co., Ltd. Systems and methods for achieving isothermal batch processing of substrates used for the production of micro-electro-mechanical-systems
CA2599888C (en) * 2005-03-31 2010-06-15 Bioxel Pharma Inc. Preparation of taxanes from 9-dihydro-13-acetylbaccatin iii
US7847111B2 (en) * 2006-06-19 2010-12-07 Canada Inc. Semi-synthetic route for the preparation of paclitaxel, docetaxel, and 10-deacetylbaccatin III from 9-dihydro-13-acetylbaccatin III

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021173A1 (en) 1992-04-17 1993-10-28 Abbott Laboratories Taxol derivatives
CA2204197A1 (en) * 1997-05-01 1998-11-01 Jian Liu Process for converting 9-dihydro-13-acetylbaccatin iii into taxol and derivatives thereof

Also Published As

Publication number Publication date
KR20030009347A (ko) 2003-01-29
WO2001055126A3 (en) 2002-01-10
US6175023B1 (en) 2001-01-16
EP1255745A2 (en) 2002-11-13
TR200400293T4 (tr) 2004-04-21
AU784830B2 (en) 2006-06-29
JP2003531826A (ja) 2003-10-28
WO2001055126A2 (en) 2001-08-02
DE60101784T2 (de) 2004-11-11
ATE257831T1 (de) 2004-01-15
CA2398655A1 (en) 2001-08-02
DE60101784D1 (de) 2004-02-19
ES2214410T3 (es) 2004-09-16
EP1255745B1 (en) 2004-01-14
AU4867801A (en) 2001-08-07
DK1255745T3 (da) 2004-05-17

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