DK128781B - Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner. - Google Patents

Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner.

Info

Publication number
DK128781B
DK128781B DK601570AA DK601570A DK128781B DK 128781 B DK128781 B DK 128781B DK 601570A A DK601570A A DK 601570AA DK 601570 A DK601570 A DK 601570A DK 128781 B DK128781 B DK 128781B
Authority
DK
Denmark
Prior art keywords
thieno
pyrimidines
furyl
nitro
preparation
Prior art date
Application number
DK601570AA
Other languages
Danish (da)
English (en)
Inventor
E Woitun
W Reuter
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK128781B publication Critical patent/DK128781B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK601570AA 1969-11-26 1970-11-25 Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner. DK128781B (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine

Publications (1)

Publication Number Publication Date
DK128781B true DK128781B (da) 1974-07-01

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
DK601570AA DK128781B (da) 1969-11-26 1970-11-25 Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner.

Country Status (13)

Country Link
US (1) US3661908A (en:Method)
BE (1) BE759493A (en:Method)
BG (2) BG17799A3 (en:Method)
CA (1) CA926865A (en:Method)
CH (3) CH567029A5 (en:Method)
DK (1) DK128781B (en:Method)
FR (1) FR2073416B1 (en:Method)
GB (1) GB1321316A (en:Method)
IE (1) IE34765B1 (en:Method)
IL (1) IL35729A (en:Method)
NL (1) NL7017210A (en:Method)
NO (1) NO129954B (en:Method)
SE (1) SE377938B (en:Method)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
AU2007243457B2 (en) 2006-04-26 2012-02-23 F. Hoffmann-La Roche Ag Pharmaceutical compounds
WO2007127183A1 (en) * 2006-04-26 2007-11-08 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and pharmaceutical compositions containing them
DE602007007323D1 (de) 2006-04-26 2010-08-05 Hoffmann La Roche Thienoä3,2-düpyrimidin-derivat geeignet als pi3k inhibitor
ZA200904531B (en) * 2006-12-07 2010-09-29 Hoffmann La Roche Phosphoinositide 3-kinase inhibitor compounds and methods of use
CL2007003520A1 (es) * 2006-12-07 2008-08-22 Piramed Ltd Genentech Inc Compuestos derivados de heterociclos sustituidos con morfolina, inhibidores de la actividad pi3 quinasa; composicion farmaceutica que comprende a dichos compuestos; kit farmaceutico; y su uso para el tratamiento profilactico o terapeutico del cancer.
WO2008152390A1 (en) * 2007-06-12 2008-12-18 F.Hoffmann-La Roche Ag Thiazoliopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase
CN101932587A (zh) * 2007-09-24 2010-12-29 吉宁特有限公司 噻唑并嘧啶pi3k抑制剂化合物及使用方法
CN101909631B (zh) 2007-10-25 2012-09-12 健泰科生物技术公司 制备噻吩并嘧啶化合物的方法
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
CN102369011A (zh) 2009-03-12 2012-03-07 健泰科生物技术公司 用于治疗造血恶性肿瘤的磷酸肌醇3-激酶抑制剂化合物与化学治疗剂的组合
SG182247A1 (en) * 2009-05-27 2012-08-30 Hoffmann La Roche Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
US8173650B2 (en) * 2009-05-27 2012-05-08 Genentech, Inc. Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
MX345155B (es) * 2009-10-12 2017-01-18 F Hoffmann-La Roche Ag * Combinaciones de un inhibidor de pi3k y un inhibidor de mek.
RU2012148699A (ru) 2010-04-16 2014-05-27 Дженентек, Инк. Foxo3a как прогностический биомаркер для эффективности ингибитора пути киназы pi3k/акт
WO2012088254A1 (en) 2010-12-22 2012-06-28 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
CA2901126C (en) 2013-02-25 2022-01-25 Genentech, Inc. Methods and compositions for detecting and treating drug resistant akt mutant

Also Published As

Publication number Publication date
IL35729A0 (en) 1971-01-28
BG17800A3 (bg) 1973-12-25
BG17799A3 (bg) 1973-12-25
FR2073416B1 (en:Method) 1975-04-18
IL35729A (en) 1974-01-14
CH567029A5 (en:Method) 1975-09-30
NO129954B (en:Method) 1974-06-17
US3661908A (en) 1972-05-09
IE34765B1 (en) 1975-08-06
SE377938B (en:Method) 1975-08-04
CH559210A5 (en:Method) 1975-02-28
CA926865A (en) 1973-05-22
CH568324A5 (en:Method) 1975-10-31
FR2073416A1 (en:Method) 1971-10-01
GB1321316A (en) 1973-06-27
BE759493A (fr) 1971-05-25
NL7017210A (en:Method) 1971-05-28
IE34765L (en) 1971-05-26

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