DK1259507T3 - Pseudopolymorf af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on, hydrochlorid - Google Patents

Pseudopolymorf af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on, hydrochlorid

Info

Publication number
DK1259507T3
DK1259507T3 DK01900939T DK01900939T DK1259507T3 DK 1259507 T3 DK1259507 T3 DK 1259507T3 DK 01900939 T DK01900939 T DK 01900939T DK 01900939 T DK01900939 T DK 01900939T DK 1259507 T3 DK1259507 T3 DK 1259507T3
Authority
DK
Denmark
Prior art keywords
pseudopolymorph
benzopyran
piperidinyl
chlorophenyl
dihydroxy
Prior art date
Application number
DK01900939T
Other languages
Danish (da)
English (en)
Inventor
Gary L Bafus
Christine M Harrison-Bowman
Gary L Silvey
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of DK1259507T3 publication Critical patent/DK1259507T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Stereophonic System (AREA)
  • Inorganic Insulating Materials (AREA)
  • Hydrogenated Pyridines (AREA)
DK01900939T 2000-01-18 2001-01-08 Pseudopolymorf af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on, hydrochlorid DK1259507T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48471700A 2000-01-18 2000-01-18
EP01900939A EP1259507B1 (de) 2000-01-18 2001-01-08 Pseudopolymorph von (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-on hydrochlorid
PCT/US2001/000519 WO2001053293A1 (en) 2000-01-18 2001-01-08 Pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one

Publications (1)

Publication Number Publication Date
DK1259507T3 true DK1259507T3 (da) 2004-11-01

Family

ID=23925305

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01900939T DK1259507T3 (da) 2000-01-18 2001-01-08 Pseudopolymorf af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on, hydrochlorid

Country Status (26)

Country Link
EP (1) EP1259507B1 (de)
JP (1) JP2003520797A (de)
KR (1) KR100806464B1 (de)
CN (1) CN1174977C (de)
AT (1) ATE273303T1 (de)
AU (1) AU2001226346A1 (de)
BR (1) BR0107726A (de)
CA (1) CA2397593C (de)
CZ (1) CZ301195B6 (de)
DE (1) DE60104822T2 (de)
DK (1) DK1259507T3 (de)
EA (1) EA005247B1 (de)
ES (1) ES2222332T3 (de)
HU (1) HUP0204126A3 (de)
IL (2) IL150638A0 (de)
MX (1) MXPA02007005A (de)
NO (1) NO322572B1 (de)
NZ (1) NZ520280A (de)
PL (1) PL200696B1 (de)
PT (1) PT1259507E (de)
SI (1) SI1259507T1 (de)
SK (1) SK287404B6 (de)
TR (1) TR200402036T4 (de)
TW (1) TWI284129B (de)
WO (1) WO2001053293A1 (de)
ZA (1) ZA200205639B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102466192B1 (ko) 2016-08-23 2022-11-14 에자이 알앤드디 매니지먼트 가부시키가이샤 간세포성 암종의 치료를 위한 조합 요법
CA3056701A1 (en) 2017-03-16 2018-09-20 Eisai R&D Management Co., Ltd. Combination therapies for the treatment of breast cancer
US20220040324A1 (en) 2018-12-21 2022-02-10 Daiichi Sankyo Company, Limited Combination of antibody-drug conjugate and kinase inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN164232B (de) * 1986-04-11 1989-02-04 Hoechst India
US5284856A (en) * 1988-10-28 1994-02-08 Hoechst Aktiengesellschaft Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives
US5908934A (en) * 1996-09-26 1999-06-01 Bristol-Myers Squibb Company Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs

Also Published As

Publication number Publication date
NZ520280A (en) 2004-04-30
MXPA02007005A (es) 2004-09-06
DE60104822D1 (de) 2004-09-16
NO20023386D0 (no) 2002-07-12
CN1174977C (zh) 2004-11-10
SK10362002A3 (sk) 2003-01-09
PT1259507E (pt) 2004-12-31
BR0107726A (pt) 2002-10-01
CA2397593A1 (en) 2001-07-26
SK287404B6 (sk) 2010-09-07
EP1259507B1 (de) 2004-08-11
WO2001053293A1 (en) 2001-07-26
NO20023386L (no) 2002-09-12
PL356165A1 (en) 2004-06-14
HUP0204126A3 (en) 2006-02-28
TWI284129B (en) 2007-07-21
ATE273303T1 (de) 2004-08-15
CN1395576A (zh) 2003-02-05
EP1259507A1 (de) 2002-11-27
JP2003520797A (ja) 2003-07-08
EA200200775A1 (ru) 2002-12-26
IL150638A0 (en) 2003-02-12
EA005247B1 (ru) 2004-12-30
TR200402036T4 (tr) 2004-10-21
CA2397593C (en) 2009-11-10
SI1259507T1 (en) 2005-02-28
HUP0204126A2 (hu) 2003-04-28
CZ20022466A3 (cs) 2002-11-13
CZ301195B6 (cs) 2009-12-02
KR100806464B1 (ko) 2008-02-21
NO322572B1 (no) 2006-10-30
KR20020069361A (ko) 2002-08-30
ES2222332T3 (es) 2005-02-01
DE60104822T2 (de) 2005-09-01
IL150638A (en) 2009-06-15
ZA200205639B (en) 2003-10-15
AU2001226346A1 (en) 2001-07-31
PL200696B1 (pl) 2009-01-30

Similar Documents

Publication Publication Date Title
DK1463716T3 (da) Pyrrolidin- og piperidinderivater som NK1-antagonister
DE60141211D1 (de) Polysilizium-halbleiterbauteil und verfahren zu dessen herstellung
NO20040845L (no) Substituerte indeno[1,2-c]isokinolinderivater og deres anvendelse
ATE312099T1 (de) 1,4-dihydropyridine als bradykininantagonisten
TR199800011T1 (xx) Benzo$g] kuinolin t�revleri
DK1349580T3 (da) Fremgangsmåde til forbedring af stabiliteten af en farmaceutisk sammensætning
DE60226131D1 (de) Strickverfahren
ATE292128T1 (de) Piperidinderivate als neurokinin 1 antagonisten
DK1147075T3 (da) Fremgangsmåde til fremstilling af L-phenylephrinhydrochlorid
RS11304A (en) Novel crystalline polymorphic forms of lercanidipine hydrochloride and process for their preparation
DE60100726D1 (de) Schalterknopf und Verfahren zu dessen Herstellung
DE50214199D1 (de) Bipolartransistor und verfahren zu dessen herstellung
DK1259507T3 (da) Pseudopolymorf af (-)-cis-2-(2-chlorphenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-methyl)piperidinyl]-4H-1-benzopyran-4-on, hydrochlorid
DE60208258D1 (de) Frequenzselektive Platte und Verfahren zu dessen Herstellung
HUP0002709A1 (hu) Eljárás 1-helyzetben szubsztituált 4-(4-fluor-fenil)-3-(hidroxi-metil)-tetrahidropiridinek redukciójára
DK1373232T3 (da) Fremgangsmåde til fremstilling af N-substituerede 2,6-dialkylmorpholiner
ATE266666T1 (de) Thiepino(3,2-b)dihydropyridine und relatierte zusammensetzungen und verfahren
PT1252155E (pt) Solvato de etanol de (-)-cis-2-(2-clorofenil)-5,7-di-hidroxi-8-[4r-(3s-hidroxi-1-metil)piperidinil]-4h-1-bezopiran-4-ona
DE60116169D1 (de) Polaritätsunabhängiger optischer Empfänger und Verfahren zu dessen Herstellung
DE50300736D1 (de) Pulverinhalativum, enthaltend den cgrp-antagonisten bibn4096 und verfahren zu dessen herstellung
ATE330948T1 (de) Verfahren zu herstellung von discodermoliden und ähnlichen verbindungen
AU2001284421A1 (en) Method of determining base sequence
DK1296955T3 (da) Fremgangsmåde til fremstilling af 1,8-naphthalimid
DK1296983T3 (da) Ny fremgangsmåde til fremstilling af pyrazolopyrimidinoner
DK1326635T3 (da) Farmaceutisk sammensætning til immunisering mod AIDS