DK125387A - Fremgangsmaade til fremstilling af macrolidforbindelser - Google Patents

Fremgangsmaade til fremstilling af macrolidforbindelser

Info

Publication number
DK125387A
DK125387A DK125387A DK125387A DK125387A DK 125387 A DK125387 A DK 125387A DK 125387 A DK125387 A DK 125387A DK 125387 A DK125387 A DK 125387A DK 125387 A DK125387 A DK 125387A
Authority
DK
Denmark
Prior art keywords
compound
formula
macrolide compounds
making
making macrolide
Prior art date
Application number
DK125387A
Other languages
English (en)
Other versions
DK165124B (da
DK125387D0 (da
DK165124C (da
Inventor
Martin Todd
Mark A Haxell
Gordon C Lawrence
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DK125387D0 publication Critical patent/DK125387D0/da
Publication of DK125387A publication Critical patent/DK125387A/da
Publication of DK165124B publication Critical patent/DK165124B/da
Application granted granted Critical
Publication of DK165124C publication Critical patent/DK165124C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/445—The saccharide radical is condensed with a heterocyclic radical, e.g. everninomycin, papulacandin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Pyrrole Compounds (AREA)
DK125387A 1986-03-12 1987-03-11 Fremgangsmaade til fremstilling af en 5-hydroxy-s541-macrolidforbindelse DK165124C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868606120A GB8606120D0 (en) 1986-03-12 1986-03-12 Process
GB8606120 1986-03-12

Publications (4)

Publication Number Publication Date
DK125387D0 DK125387D0 (da) 1987-03-11
DK125387A true DK125387A (da) 1987-09-13
DK165124B DK165124B (da) 1992-10-12
DK165124C DK165124C (da) 1993-03-01

Family

ID=10594470

Family Applications (1)

Application Number Title Priority Date Filing Date
DK125387A DK165124C (da) 1986-03-12 1987-03-11 Fremgangsmaade til fremstilling af en 5-hydroxy-s541-macrolidforbindelse

Country Status (10)

Country Link
US (1) US5378617A (da)
EP (1) EP0241147B1 (da)
JP (1) JPH07106155B2 (da)
AT (1) ATE56975T1 (da)
CA (1) CA1319636C (da)
DE (1) DE3765157D1 (da)
DK (1) DK165124C (da)
ES (1) ES2029832T3 (da)
GB (1) GB8606120D0 (da)
IE (1) IE60058B1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US5840704A (en) * 1986-07-16 1998-11-24 Pfizer Inc. Antiparasitic agents and process for their preparation
US5212322A (en) * 1986-12-11 1993-05-18 Sankyo Company, Limited Macrolide compounds, their preparation and their use
AR243528A1 (es) * 1986-12-11 1993-08-31 Sankyo Co Procedimiento para preparar compuestos de macrolida y un procedimiento para producir con los mismos una composicion parasiticida.
US5238848A (en) * 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
US5234831A (en) * 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
US5525506A (en) * 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
IN167980B (da) * 1987-01-23 1991-01-19 Pfizer
DE3883408T2 (de) * 1987-01-23 1993-12-09 Pfizer Verfahren zur Herstellung von Avermectinen und die verwendeten Kulturen.
EP0316124B1 (en) * 1987-11-09 1993-04-07 Pfizer Inc. Ethylated avermectins
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
JP2792856B2 (ja) * 1987-12-28 1998-09-03 山之内製薬株式会社 抗生物質の製造方法
GB8815967D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Antiparasitic agents
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
CN104193760B (zh) * 2014-08-29 2016-11-30 宁夏泰瑞制药股份有限公司 一种利用奈马菌素发酵液提取奈马菌素粗品的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4914624A (da) * 1972-06-08 1974-02-08
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
DE2909071A1 (de) * 1979-03-08 1980-09-11 Schmuecking Carl Guenther Epikutantestpflaster
IE59394B1 (en) * 1984-09-14 1994-02-23 American Cyanamid Co Antibiotic compounds and their preparation

Also Published As

Publication number Publication date
DE3765157D1 (de) 1990-10-31
JPH07106155B2 (ja) 1995-11-15
GB8606120D0 (en) 1986-04-16
IE870626L (en) 1987-09-12
DK165124B (da) 1992-10-12
IE60058B1 (en) 1994-05-18
ATE56975T1 (de) 1990-10-15
ES2029832T3 (es) 1992-10-01
US5378617A (en) 1995-01-03
EP0241147B1 (en) 1990-09-26
EP0241147A1 (en) 1987-10-14
DK125387D0 (da) 1987-03-11
CA1319636C (en) 1993-06-29
DK165124C (da) 1993-03-01
JPS62272986A (ja) 1987-11-27

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Legal Events

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