ATE56975T1 - Verfahren zur herstellung von macrolid-derivaten. - Google Patents

Verfahren zur herstellung von macrolid-derivaten.

Info

Publication number
ATE56975T1
ATE56975T1 AT87302099T AT87302099T ATE56975T1 AT E56975 T1 ATE56975 T1 AT E56975T1 AT 87302099 T AT87302099 T AT 87302099T AT 87302099 T AT87302099 T AT 87302099T AT E56975 T1 ATE56975 T1 AT E56975T1
Authority
AT
Austria
Prior art keywords
compound
formula
macrolid
derivatives
manufacture
Prior art date
Application number
AT87302099T
Other languages
English (en)
Inventor
Martin Todd
Mark A Haxell
Gordon C Lawrence
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ATE56975T1 publication Critical patent/ATE56975T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/445—The saccharide radical is condensed with a heterocyclic radical, e.g. everninomycin, papulacandin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Pyrrole Compounds (AREA)
AT87302099T 1986-03-12 1987-03-11 Verfahren zur herstellung von macrolid-derivaten. ATE56975T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868606120A GB8606120D0 (en) 1986-03-12 1986-03-12 Process
EP87302099A EP0241147B1 (de) 1986-03-12 1987-03-11 Verfahren zur Herstellung von Macrolid-Derivaten

Publications (1)

Publication Number Publication Date
ATE56975T1 true ATE56975T1 (de) 1990-10-15

Family

ID=10594470

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87302099T ATE56975T1 (de) 1986-03-12 1987-03-11 Verfahren zur herstellung von macrolid-derivaten.

Country Status (10)

Country Link
US (1) US5378617A (de)
EP (1) EP0241147B1 (de)
JP (1) JPH07106155B2 (de)
AT (1) ATE56975T1 (de)
CA (1) CA1319636C (de)
DE (1) DE3765157D1 (de)
DK (1) DK165124C (de)
ES (1) ES2029832T3 (de)
GB (1) GB8606120D0 (de)
IE (1) IE60058B1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US5840704A (en) * 1986-07-16 1998-11-24 Pfizer Inc. Antiparasitic agents and process for their preparation
AR243528A1 (es) * 1986-12-11 1993-08-31 Sankyo Co Procedimiento para preparar compuestos de macrolida y un procedimiento para producir con los mismos una composicion parasiticida.
US5212322A (en) * 1986-12-11 1993-05-18 Sankyo Company, Limited Macrolide compounds, their preparation and their use
US5238848A (en) * 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
IN167980B (de) * 1987-01-23 1991-01-19 Pfizer
US5234831A (en) * 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
US5525506A (en) * 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
BG48572A3 (en) * 1987-01-23 1991-03-15 Pfizer Method for preparing of avermectines
ATE87926T1 (de) * 1987-11-09 1993-04-15 Pfizer Ethylierte avermectine.
GB8726730D0 (en) 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
JP2792856B2 (ja) * 1987-12-28 1998-09-03 山之内製薬株式会社 抗生物質の製造方法
GB8815967D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Antiparasitic agents
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
CN104193760B (zh) * 2014-08-29 2016-11-30 宁夏泰瑞制药股份有限公司 一种利用奈马菌素发酵液提取奈马菌素粗品的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4914624A (de) * 1972-06-08 1974-02-08
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
DE2909071A1 (de) * 1979-03-08 1980-09-11 Schmuecking Carl Guenther Epikutantestpflaster
CS268803B2 (en) * 1984-09-14 1990-04-11 Glaxo Group Ltd Pesticide

Also Published As

Publication number Publication date
DK125387D0 (da) 1987-03-11
CA1319636C (en) 1993-06-29
IE60058B1 (en) 1994-05-18
IE870626L (en) 1987-09-12
JPH07106155B2 (ja) 1995-11-15
DK165124B (da) 1992-10-12
JPS62272986A (ja) 1987-11-27
ES2029832T3 (es) 1992-10-01
DK125387A (da) 1987-09-13
DK165124C (da) 1993-03-01
US5378617A (en) 1995-01-03
GB8606120D0 (en) 1986-04-16
EP0241147A1 (de) 1987-10-14
EP0241147B1 (de) 1990-09-26
DE3765157D1 (de) 1990-10-31

Similar Documents

Publication Publication Date Title
ATE56975T1 (de) Verfahren zur herstellung von macrolid-derivaten.
DE3687946T2 (de) Verfahren zur herstellung der 2-keto-l-gulonsaeure.
ATE124458T1 (de) Verfahren zur herstellung von bis-homo-gamma- linolensäure.
ATE118496T1 (de) Verfahren zur herstellung von 4-o- dopaminphosphaten und dopaminderivate.
ATE155172T1 (de) Verfahren zur herstellung einer mehrfach ungesättigten fettsäure des omega 9 typs
DE3680938D1 (de) Verfahren zur herstellung von substituierten 3-chinolincarbonsaeuren.
DE3882453T2 (de) Verfahren zur Herstellung von Ibuprofen.
DE68927103D1 (de) Verfahren zur herstellung von gamma- und delta-lactonen
DE3785023T2 (de) Verfahren zur herstellung von arachidonsaeure.
DE3584218D1 (de) Herstellung von derivaten von a-21978c.
ATE104268T1 (de) Verfahren zur herstellung eines alphaketocarbons|ureester.
ATE116636T1 (de) Verfahren zur herstellung von 2,6- dichlordiphenylaminessigsäurederivaten.
ATE177091T1 (de) Chinasäurederivate und verfahren zur herstellung von chinasäurederivaten
DE3579663D1 (de) Verfahren zur herstellung aromatisch substituierter l-aminosaeuren.
DE68912236D1 (de) Verfahren zur Herstellung von hochgradig ungesättigten Fettsäuren.
ATE150003T1 (de) Verfahren zur herstellung von l-(-)-carnitin aus abfallprodukten mit entgegengesetzter konfiguration
ATE139989T1 (de) Verfahren zur herstellung von niedrigem alkyl-2- oxo-l-gulonat
ATE135369T1 (de) Chemisches verfahren zur herstellung des antibiotikums l 17392 (deglukoteicoplanin) und dessen salze
ATE60580T1 (de) Verfahren zur herstellung von estern.
DE69015499D1 (de) Verfahren zur Herstellung von Castanosperminestern.
ATE144285T1 (de) Mikrobiologisches verfahren zur herstellung von 5-hydroxy-2-pyrazincarbonsäure
DE69327984D1 (de) Verfahren zur Modifizierung von Lipasen