ATE150003T1 - Verfahren zur herstellung von l-(-)-carnitin aus abfallprodukten mit entgegengesetzter konfiguration - Google Patents

Verfahren zur herstellung von l-(-)-carnitin aus abfallprodukten mit entgegengesetzter konfiguration

Info

Publication number
ATE150003T1
ATE150003T1 AT94830152T AT94830152T ATE150003T1 AT E150003 T1 ATE150003 T1 AT E150003T1 AT 94830152 T AT94830152 T AT 94830152T AT 94830152 T AT94830152 T AT 94830152T AT E150003 T1 ATE150003 T1 AT E150003T1
Authority
AT
Austria
Prior art keywords
carnitine
producing
waste products
opposite configuration
lactone
Prior art date
Application number
AT94830152T
Other languages
English (en)
Inventor
Fabio Giannessi
Roberto Castagnani
Maria Ornella Tinti
Angelis Francesco De
Witt Paolo De
Domenico Misiti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of ATE150003T1 publication Critical patent/ATE150003T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C07D305/12—Beta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Processing Of Solid Wastes (AREA)
  • Switches Operated By Changes In Physical Conditions (AREA)
  • Lighting Device Outwards From Vehicle And Optical Signal (AREA)
  • Fertilizers (AREA)
AT94830152T 1993-04-08 1994-03-31 Verfahren zur herstellung von l-(-)-carnitin aus abfallprodukten mit entgegengesetzter konfiguration ATE150003T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM930226A IT1261230B (it) 1993-04-08 1993-04-08 Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione.

Publications (1)

Publication Number Publication Date
ATE150003T1 true ATE150003T1 (de) 1997-03-15

Family

ID=11401703

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94830152T ATE150003T1 (de) 1993-04-08 1994-03-31 Verfahren zur herstellung von l-(-)-carnitin aus abfallprodukten mit entgegengesetzter konfiguration

Country Status (14)

Country Link
US (1) US5491260A (de)
EP (1) EP0623588B1 (de)
JP (1) JP3502657B2 (de)
KR (1) KR100301951B1 (de)
AT (1) ATE150003T1 (de)
CA (1) CA2120811C (de)
DE (1) DE69401979T2 (de)
DK (1) DK0623588T3 (de)
ES (1) ES2099563T3 (de)
GR (1) GR3023594T3 (de)
HK (1) HK1005867A1 (de)
IT (1) IT1261230B (de)
TW (1) TW275613B (de)
ZA (1) ZA942428B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1261828B (it) 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
IT1276207B1 (it) * 1995-09-29 1997-10-27 Sigma Tau Ind Farmaceuti Procedimento per la preparazione del (s)-b-idrossi-gamma- butirrolattone
KR100255039B1 (ko) * 1997-07-28 2000-05-01 박영구 L-카르니틴의제조방법
IT1297120B1 (it) * 1997-12-16 1999-08-03 Sigma Tau Ind Farmaceuti Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina
DE10027391B4 (de) * 2000-06-02 2006-05-04 Wella Ag Oligomere und Polymere aus Crotonbetain oder Crotonbetainderivaten
EP2409972A1 (de) * 2010-07-21 2012-01-25 Lonza Ltd. Verfahren zur Herstellung von Carnitin aus B-Lactonen
EP2409965A1 (de) * 2010-07-21 2012-01-25 Lonza Ltd. Verfahren zur Herstellung von Carnitin mittels Cycloaddition
EP2595973B1 (de) * 2010-07-21 2017-07-12 Lonza Ltd. Verfahren zur herstellung von carnitin aus beta-lactonen
EP2468739A1 (de) * 2010-12-22 2012-06-27 Lonza Ltd. Verfahren zur Herstellung von Carnitin aus B-Lactonen

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE664500A (de) *
ES332080A1 (es) * 1965-10-15 1967-10-01 Otsuka Pharma Co Ltd Procedimiento para obtencion de complejos de sales opticamente activas de hidroxido de nitrilo,carnitina y acidos glutamicos n-acilos.
IT1156852B (it) * 1978-07-10 1987-02-04 Sigma Tau Ind Farmaceuti Procedimento industriale per la preparazione del d'canforato della l carnitinammide e del d canforato della d carnitinammide e sue applicazioni
IT1136945B (it) * 1981-03-18 1986-09-03 Anic Spa Processo per la preparazione di l-carnitina
JPS59183694A (ja) * 1983-04-05 1984-10-18 Hamari Yakuhin Kogyo Kk 光学活性なカルニチンの生化学的製造法
JPS59192095A (ja) * 1983-04-13 1984-10-31 Ajinomoto Co Inc Ｌ−カルニチンの製造法
DD221905B1 (de) * 1983-11-03 1987-03-18 Univ Leipzig Verfahren zur herstellung von l(-)-carnitin und seinen derivaten
CH664374A5 (de) * 1985-02-27 1988-02-29 Lonza Ag Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg.
US5200526A (en) * 1987-04-27 1993-04-06 The Governors Of The University Of Alberta Syntheses of optically pure α-amino acids from 3-amino-2-oxetanone salts
JPH0291049A (ja) * 1988-09-21 1990-03-30 Lonza Ag ｒ―ブチロベタインの製造方法
IT1231751B (it) * 1989-04-12 1991-12-21 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
IE902689A1 (en) * 1989-07-28 1991-02-27 Lonza Ag A method of discontinuous production of l-carnitine by a¹microbiological process
IT1240833B (it) * 1990-05-14 1993-12-17 Sigma Tau Ind Farmaceuti Procedimento biocatalitico per la produzione di l-(-)- carnitina da crotonilbetaina e ceppi di proteeae per l'uso in tale procedimento
IT1245699B (it) * 1991-05-29 1994-10-14 Sigma Tau Ind Farmaceuti Derivati della l-carnitina quali agenti terapeutici per il trattamento delle miopatie, della degenarazione neuronale e per inibire la proteolisi
IT1256705B (it) * 1992-12-21 1995-12-12 Sigma Tau Ind Farmaceuti Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione.

Also Published As

Publication number Publication date
DE69401979D1 (de) 1997-04-17
ZA942428B (en) 1994-11-29
EP0623588A1 (de) 1994-11-09
DE69401979T2 (de) 1997-06-26
DK0623588T3 (da) 1997-07-21
KR100301951B1 (ko) 2001-10-22
CA2120811C (en) 2004-10-26
ITRM930226A0 (it) 1993-04-08
JP3502657B2 (ja) 2004-03-02
EP0623588B1 (de) 1997-03-12
JPH06311888A (ja) 1994-11-08
GR3023594T3 (en) 1997-08-29
CA2120811A1 (en) 1994-10-09
IT1261230B (it) 1996-05-09
US5491260A (en) 1996-02-13
ITRM930226A1 (it) 1994-10-08
ES2099563T3 (es) 1997-05-16
HK1005867A1 (en) 1999-01-29
TW275613B (de) 1996-05-11

Similar Documents

Publication Publication Date Title
ATE137493T1 (de) Verfahren zur herstellung von zwischenprodukten zur verwendung in der herstellung von alkoxyiminoacetamide
DE3687946D1 (de) Verfahren zur herstellung der 2-keto-l-gulonsaeure.
ATE132904T1 (de) Verfahren zur herstellung von trehalulose und isomaltulose
DE3882242T2 (de) Fermentationsverfahren zur Herstellung von 2-Keto-L-Gulonsäuren.
ATE150003T1 (de) Verfahren zur herstellung von l-(-)-carnitin aus abfallprodukten mit entgegengesetzter konfiguration
DE69615183T2 (de) Kontinuerliches hydrolyse-verfahren zur herstellung von 2-hydroxy-4-methylthiobutansäure oder salze davon
DE3765157D1 (de) Verfahren zur herstellung von macrolid-derivaten.
DE69221841T2 (de) Verfahren zur Herstellung von gereinigtem Xanthangummi
DE3785023D1 (de) Verfahren zur herstellung von arachidonsaeure.
ATE129699T1 (de) Verfahren zur herstellung gereinigter alkansulfonsäuren.
ATE145641T1 (de) Verfahren zur herstellung von l-(-)-carnitin aus abfallprodukten mit entgegengesetzter konfiguration
DE3764875D1 (de) Verfahren zur herstellung von penemderivaten.
DE68912236T2 (de) Verfahren zur Herstellung von hochgradig ungesättigten Fettsäuren.
ATE132535T1 (de) Verfahren zur diskontinuierlichen herstellung von l-carnitin auf mikrobiologischem weg
ATE124947T1 (de) Verfahren zur herstellung substituierter cyclobutane.
ATE207139T1 (de) Verfahren zur herstellung von butantetracarbonsäure
ATE133409T1 (de) Verfahren zur herstellung von 2-oxindol-1- carboxamiden
ATE135369T1 (de) Chemisches verfahren zur herstellung des antibiotikums l 17392 (deglukoteicoplanin) und dessen salze
ATE104951T1 (de) Verfahren zur herstellung von vinyl-gaba.
DE69015499D1 (de) Verfahren zur Herstellung von Castanosperminestern.
ATE120748T1 (de) Verfahren zur herstellung von 2-acylamino-9-acyl- 6-halogen-purinen.
ATE10623T1 (de) Verfahren zur herstellung von l-prolin.
DE68904680T2 (de) Carbamatderivate und verfahren zu ihrer herstellung.
ATE187452T1 (de) Zwischenprodukte für 1-carbacephalosporin und verfahren zur herstellung dieser
DE69122545D1 (de) Verfahren zur Herstellung von menschlichem Nervenwachstumsfaktor durch Genmanipulation

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification