DK1242452T3 - Kimære natriuretiske peptider - Google Patents

Kimære natriuretiske peptider

Info

Publication number
DK1242452T3
DK1242452T3 DK00988092T DK00988092T DK1242452T3 DK 1242452 T3 DK1242452 T3 DK 1242452T3 DK 00988092 T DK00988092 T DK 00988092T DK 00988092 T DK00988092 T DK 00988092T DK 1242452 T3 DK1242452 T3 DK 1242452T3
Authority
DK
Denmark
Prior art keywords
natriuretic peptides
chimeric natriuretic
peptides
chimeric
natriuretics
Prior art date
Application number
DK00988092T
Other languages
Danish (da)
English (en)
Inventor
John Burnett Jr
Ondrej Lisy
Original Assignee
Mayo Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Foundation filed Critical Mayo Foundation
Application granted granted Critical
Publication of DK1242452T3 publication Critical patent/DK1242452T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK00988092T 1999-12-17 2000-12-15 Kimære natriuretiske peptider DK1242452T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/466,268 US6407211B1 (en) 1999-12-17 1999-12-17 Chimeric natriuretic peptides
PCT/US2000/034080 WO2001044284A2 (fr) 1999-12-17 2000-12-15 Peptides natriuretiques chimeres

Publications (1)

Publication Number Publication Date
DK1242452T3 true DK1242452T3 (da) 2007-06-11

Family

ID=23851133

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00988092T DK1242452T3 (da) 1999-12-17 2000-12-15 Kimære natriuretiske peptider

Country Status (11)

Country Link
US (4) US6407211B1 (fr)
EP (1) EP1242452B1 (fr)
JP (1) JP5031964B2 (fr)
AT (1) ATE353916T1 (fr)
AU (1) AU2433901A (fr)
CA (1) CA2395585C (fr)
DE (1) DE60033431T2 (fr)
DK (1) DK1242452T3 (fr)
ES (1) ES2282160T3 (fr)
PT (1) PT1242452E (fr)
WO (1) WO2001044284A2 (fr)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000071576A2 (fr) * 1999-05-24 2000-11-30 Mayo Foundation For Medical Education And Research Vecteurs d'adenovirus codant pour le peptide natriuretique du cerveau
US6407211B1 (en) 1999-12-17 2002-06-18 Mayo Foundation For Medical Education And Research Chimeric natriuretic peptides
US20040063630A1 (en) * 2002-03-18 2004-04-01 Scios, Inc. Treatment of congestive heart failure with natriuretic peptide and a diuretic
US20050113286A1 (en) * 2002-03-18 2005-05-26 Schreiner George F. Methods for treating congestive heart failure
US20080214437A1 (en) * 2002-09-06 2008-09-04 Mohapatra Shyam S Methods and compositions for reducing activity of the atrial natriuretic peptide receptor and for treatment of diseases
AU2003270427A1 (en) * 2002-09-06 2004-03-29 University Of South Florida Cellular delivery of natriuretic peptides
AU2003268531A1 (en) 2002-09-06 2004-03-29 University Of South Florida Materials and methods for treatment of allergic diseases
EP1569683B1 (fr) 2002-11-26 2010-03-03 Biocon Limited Composes natriuretiques modifies, leurs conjugues et leur utilisation
WO2004097368A2 (fr) * 2003-04-28 2004-11-11 Ciphergen Biosystems, Inc. Dosages immunologiques ameliores
ES2354881T3 (es) 2003-06-20 2011-03-18 Mayo Foundation For Medical Education And Research Isoformas de péptido natriurético cerebral.
GB2403533A (en) 2003-06-30 2005-01-05 Orion Corp Atrial natriuretic peptide and brain natriuretic peptide and assays and uses thereof
US7445933B2 (en) * 2003-07-16 2008-11-04 Abbott Laboratories, Inc. Stable calibrators or controls for measuring human natriuretic peptides
US7291501B2 (en) * 2003-07-16 2007-11-06 Abbott Laboratories Stable compositions for measuring human natriuretic peptides
US8076288B2 (en) 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
WO2005094420A2 (fr) * 2004-02-17 2005-10-13 University Of South Florida Materiaux et methodes permettant de traiter des troubles inflammatoires et lies a la proliferation cellulaire
ES2365023T3 (es) 2004-04-21 2011-09-20 Enobia Pharma Inc. Conjugados de administración ósea y método de uso de los mismos para dirigir proteínas a hueso.
ATE496060T1 (de) * 2004-07-15 2011-02-15 Univ Queensland Proteinartige verbindungen und anwendungen davon
AT500800B1 (de) * 2004-09-08 2008-07-15 Biomedica Medizinprodukte Gmbh Verfahren zur bestimmung von probnp
US20080207505A1 (en) * 2005-01-12 2008-08-28 James Kenneth D Bna Conjugates and Methods of Use
US8263545B2 (en) 2005-02-11 2012-09-11 Amylin Pharmaceuticals, Inc. GIP analog and hybrid polypeptides with selectable properties
US8404637B2 (en) 2005-02-11 2013-03-26 Amylin Pharmaceuticals, Llc GIP analog and hybrid polypeptides with selectable properties
PT2510942E (pt) 2005-04-07 2015-12-28 Cardiorentis Ag Utilização de péptido natriurético para o tratamento de insuficiência cardíaca
EP1922336B1 (fr) * 2005-08-11 2012-11-21 Amylin Pharmaceuticals, LLC Polypeptides hybrides presentant des proprietes selectionnables
US7803901B2 (en) * 2005-09-16 2010-09-28 Mayo Foundation For Medical Education And Research Polypeptides with natriuresis activity
US8580746B2 (en) * 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
AU2007233123A1 (en) * 2006-03-30 2007-10-11 Palatin Technologies, Inc. Linear natriuretic peptide constructs
MX2008012663A (es) * 2006-03-30 2008-10-13 Palatin Technologies Inc Constructos ciclicos de peptidos natriureticos.
CA2656990A1 (fr) * 2006-04-28 2007-11-08 University Of South Florida Matieres et procedes destines a reduire une inflammation par inhibition du recepteur du peptide natriuretique auriculaire
BRPI0716416A2 (pt) * 2006-08-08 2016-10-11 Mayo Foundation polipeptídeo substancialmente puro entre 37 e 47 besíduos de aminoácido de comprimento, ácido nucléico isolado, vetor: célula hospedeira e composição farmacêutica
US8497240B2 (en) 2006-08-17 2013-07-30 Amylin Pharmaceuticals, Llc DPP-IV resistant GIP hybrid polypeptides with selectable properties
EP2059524A4 (fr) 2006-09-08 2009-11-25 Mayo Foundation Polypeptides aquaretiques et natriuretiques depourvus d'activite vasodilatatoire
US20100062984A1 (en) * 2007-01-25 2010-03-11 Rajiv Kumar Fgf-23 polypeptides
AU2008279379B2 (en) * 2007-07-20 2016-03-24 Mayo Foundation For Medical Education And Research Natriuretic polypeptides
WO2009036448A2 (fr) 2007-09-15 2009-03-19 Mayo Foundation For Medical Education And Research Agonistes des récepteurs peptidiques natriurétiques de type c
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US20110152194A1 (en) * 2008-06-06 2011-06-23 Mayo Foundation For Medical Education And Research Chimeric natriuretic polypeptides and methods for inhibiting cardiac remodeling
JP5765813B2 (ja) * 2008-09-19 2015-08-19 ウェルズ ファーゴ バンク ナショナル アソシエイション 治療用ペプチドのポリマーコンジュゲート
EP2334335A1 (fr) * 2008-09-19 2011-06-22 Nektar Therapeutics Conjugués polymères de peptides cd-np
US8642550B2 (en) * 2008-10-24 2014-02-04 Mayo Foundation For Medical Education And Research Chimeric natriuretic peptides without hypotensive inducing capability
US8455438B2 (en) 2008-12-29 2013-06-04 Mayo Foundation For Medical Education And Research Natriuretic polypeptides for reducing or preventing restenosis
WO2010129655A2 (fr) * 2009-05-05 2010-11-11 Mayo Foundation For Medical Education And Research Polypeptides natriurétiques comportant des mutations dans leurs cycles disulfure
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WO2012115772A2 (fr) 2011-02-25 2012-08-30 Medtronic, Inc. Thérapie pour néphropathie et/ou insuffisance cardiaque
US10184942B2 (en) 2011-03-17 2019-01-22 University Of South Florida Natriuretic peptide receptor as a biomarker for diagnosis and prognosis of cancer
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WO2013070741A1 (fr) * 2011-11-11 2013-05-16 Mayo Foundation For Medical Education And Research Procédés et matériaux pour la régulation de la fonction de polypeptides natriurétiques
US9611305B2 (en) 2012-01-06 2017-04-04 Mayo Foundation For Medical Education And Research Treating cardiovascular or renal diseases
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AU2014208851B2 (en) * 2013-01-25 2016-12-22 Cardiorentis Ltd. A natriuretic peptide, a diuretic peptide or a vaso dilatory peptide for use in methods of treating cardiovascular indications
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WO2017058822A1 (fr) 2015-09-28 2017-04-06 Alexion Pharmaceuticals, Inc. Identification de régimes posologiques efficaces pour une thérapie de l'hypophosphatasie de remplacement de l'enzyme phosphatase alcaline non spécifique à des tissus (tnsalp)
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CN109152820A (zh) 2016-04-01 2019-01-04 阿雷克森制药公司 用碱性磷酸酶治疗肌肉无力
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EP3600383A4 (fr) 2017-03-31 2020-10-28 Alexion Pharmaceuticals, Inc. Méthodes de traitement de l'hypophosphatasie (hpp) chez l'adulte et l'adolescent
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Also Published As

Publication number Publication date
US6407211B1 (en) 2002-06-18
DE60033431T2 (de) 2007-11-29
EP1242452B1 (fr) 2007-02-14
US7384917B2 (en) 2008-06-10
US6818619B2 (en) 2004-11-16
CA2395585C (fr) 2014-09-09
EP1242452A2 (fr) 2002-09-25
PT1242452E (pt) 2007-05-31
US20020082219A1 (en) 2002-06-27
US20090170756A1 (en) 2009-07-02
AU2433901A (en) 2001-06-25
ES2282160T3 (es) 2007-10-16
JP2003517005A (ja) 2003-05-20
WO2001044284A3 (fr) 2002-01-31
WO2001044284A2 (fr) 2001-06-21
JP5031964B2 (ja) 2012-09-26
DE60033431D1 (de) 2007-03-29
US20030069186A1 (en) 2003-04-10
US7964564B2 (en) 2011-06-21
US20050059600A1 (en) 2005-03-17
ATE353916T1 (de) 2007-03-15
CA2395585A1 (fr) 2001-06-21

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