DK1233960T3 - Polymorft salt af anti-migræne lægemiddel - Google Patents

Polymorft salt af anti-migræne lægemiddel

Info

Publication number
DK1233960T3
DK1233960T3 DK00954864T DK00954864T DK1233960T3 DK 1233960 T3 DK1233960 T3 DK 1233960T3 DK 00954864 T DK00954864 T DK 00954864T DK 00954864 T DK00954864 T DK 00954864T DK 1233960 T3 DK1233960 T3 DK 1233960T3
Authority
DK
Denmark
Prior art keywords
migraine drug
polymorphic salt
polymorphic
salt
migraine
Prior art date
Application number
DK00954864T
Other languages
Danish (da)
English (en)
Inventor
Arthur Bentley
Simon Arnold Howard-Field
Ronald James Ogilvie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK1233960T3 publication Critical patent/DK1233960T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Rheumatology (AREA)
  • Addiction (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK00954864T 1999-09-28 2000-09-14 Polymorft salt af anti-migræne lægemiddel DK1233960T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9922963.5A GB9922963D0 (en) 1999-09-28 1999-09-28 Polymorphic salt
PCT/IB2000/001305 WO2001023377A2 (en) 1999-09-28 2000-09-14 Polymorphic salt

Publications (1)

Publication Number Publication Date
DK1233960T3 true DK1233960T3 (da) 2003-10-27

Family

ID=10861767

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00954864T DK1233960T3 (da) 1999-09-28 2000-09-14 Polymorft salt af anti-migræne lægemiddel

Country Status (50)

Country Link
US (1) US6369094B1 (es)
EP (1) EP1233960B1 (es)
JP (1) JP3795395B2 (es)
KR (1) KR100479897B1 (es)
CN (1) CN1155594C (es)
AP (1) AP2004A (es)
AR (1) AR025779A1 (es)
AT (1) ATE246185T1 (es)
AU (1) AU779580B2 (es)
BG (1) BG65161B1 (es)
BR (1) BR0014272A (es)
CA (1) CA2379572C (es)
CO (1) CO5180567A1 (es)
CR (1) CR6561A (es)
CU (1) CU23200A3 (es)
CZ (1) CZ2002971A3 (es)
DE (1) DE60004262T2 (es)
DK (1) DK1233960T3 (es)
DZ (1) DZ3254A1 (es)
EA (1) EA004510B1 (es)
EE (1) EE200200171A (es)
EG (1) EG24143A (es)
ES (1) ES2200911T3 (es)
GB (1) GB9922963D0 (es)
GE (1) GEP20043365B (es)
GT (1) GT200000159A (es)
HK (1) HK1048628B (es)
HR (1) HRP20020270B1 (es)
HU (1) HUP0202821A3 (es)
IL (1) IL147154A (es)
IS (1) IS2162B (es)
MA (1) MA26821A1 (es)
MX (1) MXPA02003311A (es)
MY (1) MY121170A (es)
NO (1) NO321936B1 (es)
NZ (1) NZ516093A (es)
OA (1) OA12024A (es)
PA (1) PA8498901A1 (es)
PE (1) PE20010662A1 (es)
PL (1) PL354960A1 (es)
PT (1) PT1233960E (es)
SI (1) SI1233960T1 (es)
SK (1) SK3982002A3 (es)
TN (1) TNSN00187A1 (es)
TR (1) TR200200804T2 (es)
TW (1) TWI265926B (es)
UA (1) UA72272C2 (es)
WO (1) WO2001023377A2 (es)
YU (1) YU2602A (es)
ZA (1) ZA200202406B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7214711B2 (en) * 1998-12-23 2007-05-08 Neurotherapeutics Pharma Llc Method of treating migraine headache without aura
US20060025387A1 (en) * 1998-12-23 2006-02-02 Cytoscan Sciences Llc Compositions and methods for the treatment of disorders of the central and peripheral nervous systems
US8008283B2 (en) * 1998-12-23 2011-08-30 Neurotherapeutics Pharma, Inc. Methods and compositions for the treatment of neuropsychiatric disorders
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
GB0018968D0 (en) * 2000-08-02 2000-09-20 Pfizer Ltd Particulate composition
GB0312478D0 (en) * 2003-05-30 2003-07-09 Pfizer Ltd Improved process
US7132549B2 (en) 2003-05-30 2006-11-07 Pfizer Inc. Process
CA2588465C (en) * 2004-12-03 2013-10-01 Merck & Co., Inc. Pharmaceutical composition containing an anti-nucleating agent
JP2009511629A (ja) * 2005-10-17 2009-03-19 ニューロセラピューティクス ファーマ, インコーポレイテッド 中枢神経系疾患の調節に有用な利尿薬様化合物類似体
KR100814109B1 (ko) * 2006-01-09 2008-03-14 한국생명공학연구원 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로함유하는 약학적 조성물
TWI394753B (zh) * 2006-03-17 2013-05-01 Otsuka Pharma Co Ltd 新穎替妥牟拉(tetomilast)晶體
WO2010116386A2 (en) * 2009-04-08 2010-10-14 Biophore India Pharmaceuticals Pvt. Ltd. Novel polymorph of eletriptan hydrobromide and process for the preparation thereof
PL2493312T3 (pl) 2009-10-26 2022-01-03 Merck Sharp & Dohme Corp. Kompozycje farmaceutyczne w postaci ciała stałego zawierające inhibitor integrazy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5559129A (en) 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5559246A (en) 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
RO111767B1 (ro) * 1990-10-15 1997-01-30 Pfizer Derivati de indol, procedee si intermediari pentru prepararea acestora, compozitii farmaceutice si metoda pentru tratarea unor afectiuni
US5545644A (en) 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5578612A (en) 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5607951A (en) 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
GB9417310D0 (en) * 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
US5998462A (en) * 1996-12-16 1999-12-07 Allelix Biopharmaceuticals Inc. 5-alkyl indole compounds
US6166025A (en) * 1997-07-03 2000-12-26 Pfizer Inc. Pharmaceutical compositions containing eletriptran hemisulphate and caffeine

Also Published As

Publication number Publication date
CO5180567A1 (es) 2002-07-30
TNSN00187A1 (fr) 2005-11-10
HK1048628B (zh) 2004-10-21
WO2001023377A3 (en) 2002-03-07
GT200000159A (es) 2002-03-20
GB9922963D0 (en) 1999-12-01
KR20020032627A (ko) 2002-05-03
TWI265926B (en) 2006-11-11
ZA200202406B (en) 2003-05-28
CR6561A (es) 2005-04-04
HUP0202821A2 (hu) 2003-01-28
EP1233960B1 (en) 2003-07-30
WO2001023377A2 (en) 2001-04-05
EA200200302A1 (ru) 2002-10-31
SI1233960T1 (en) 2003-12-31
JP2003510318A (ja) 2003-03-18
AP2002002457A0 (en) 2002-06-30
IL147154A0 (en) 2002-08-14
IS6223A (is) 2002-01-08
AU6721300A (en) 2001-04-30
AU779580B2 (en) 2005-01-27
AR025779A1 (es) 2002-12-11
EE200200171A (et) 2003-06-16
DZ3254A1 (fr) 2001-04-05
PT1233960E (pt) 2003-11-28
GEP20043365B (en) 2004-05-10
EG24143A (en) 2008-08-06
DE60004262T2 (de) 2004-01-22
MA26821A1 (fr) 2004-12-20
PA8498901A1 (es) 2004-02-07
TR200200804T2 (tr) 2002-07-22
DE60004262D1 (de) 2003-09-04
KR100479897B1 (ko) 2005-03-31
JP3795395B2 (ja) 2006-07-12
HRP20020270B1 (en) 2004-04-30
CU23200A3 (es) 2007-04-06
CA2379572C (en) 2006-11-14
NO20021525D0 (no) 2002-03-26
SK3982002A3 (en) 2003-05-02
NZ516093A (en) 2005-01-28
MXPA02003311A (es) 2002-10-04
ATE246185T1 (de) 2003-08-15
YU2602A (sh) 2004-11-25
OA12024A (en) 2006-04-19
AP2004A (en) 2009-06-10
NO20021525L (no) 2002-03-26
IL147154A (en) 2005-11-20
EA004510B1 (ru) 2004-04-29
IS2162B (is) 2006-11-15
US6369094B1 (en) 2002-04-09
PE20010662A1 (es) 2001-06-23
UA72272C2 (uk) 2005-02-15
BR0014272A (pt) 2002-05-21
HUP0202821A3 (en) 2003-12-29
CA2379572A1 (en) 2001-04-05
PL354960A1 (en) 2004-03-22
CN1364166A (zh) 2002-08-14
ES2200911T3 (es) 2004-03-16
BG106240A (en) 2002-07-31
WO2001023377A9 (en) 2002-03-28
MY121170A (en) 2005-12-30
NO321936B1 (no) 2006-07-24
EP1233960A2 (en) 2002-08-28
HRP20020270A2 (en) 2003-06-30
BG65161B1 (bg) 2007-04-30
CN1155594C (zh) 2004-06-30
CZ2002971A3 (cs) 2003-04-16
HK1048628A1 (en) 2003-04-11

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