DK1216253T3 - Fremgangsmåde til fremstilling af methylendiphosphonsyrer og salte deraf - Google Patents

Fremgangsmåde til fremstilling af methylendiphosphonsyrer og salte deraf

Info

Publication number
DK1216253T3
DK1216253T3 DK00958856T DK00958856T DK1216253T3 DK 1216253 T3 DK1216253 T3 DK 1216253T3 DK 00958856 T DK00958856 T DK 00958856T DK 00958856 T DK00958856 T DK 00958856T DK 1216253 T3 DK1216253 T3 DK 1216253T3
Authority
DK
Denmark
Prior art keywords
salts
preparation
methylenediphosphonic
acids
methylenediphosphonic acids
Prior art date
Application number
DK00958856T
Other languages
Danish (da)
English (en)
Inventor
Mark Purdie
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Application granted granted Critical
Publication of DK1216253T3 publication Critical patent/DK1216253T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3856—Polyphosphonic acids containing halogen or nitro(so) substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3843—Polyphosphonic acids containing no further substituents than -PO3H2 groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK00958856T 1999-09-17 2000-09-11 Fremgangsmåde til fremstilling af methylendiphosphonsyrer og salte deraf DK1216253T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9903345A SE9903345D0 (sv) 1999-09-17 1999-09-17 Novel process
PCT/GB2000/003473 WO2001021629A1 (en) 1999-09-17 2000-09-11 Process for preparing methylene bisphosphonic and salts

Publications (1)

Publication Number Publication Date
DK1216253T3 true DK1216253T3 (da) 2003-09-15

Family

ID=20417040

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00958856T DK1216253T3 (da) 1999-09-17 2000-09-11 Fremgangsmåde til fremstilling af methylendiphosphonsyrer og salte deraf

Country Status (24)

Country Link
US (2) US6657076B1 (ja)
EP (1) EP1216253B1 (ja)
JP (1) JP4881524B2 (ja)
KR (1) KR100776105B1 (ja)
CN (1) CN1150200C (ja)
AR (1) AR029393A1 (ja)
AT (1) ATE242778T1 (ja)
AU (1) AU771628B2 (ja)
BR (1) BR0014057A (ja)
CA (1) CA2383829C (ja)
CO (1) CO5231228A1 (ja)
DE (1) DE60003323T2 (ja)
DK (1) DK1216253T3 (ja)
ES (1) ES2200921T3 (ja)
HK (1) HK1045696B (ja)
IL (2) IL148442A (ja)
MY (1) MY119965A (ja)
NO (1) NO331532B1 (ja)
NZ (1) NZ517552A (ja)
PT (1) PT1216253E (ja)
SE (1) SE9903345D0 (ja)
TW (1) TWI274057B (ja)
WO (1) WO2001021629A1 (ja)
ZA (1) ZA200201661B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903345D0 (sv) * 1999-09-17 1999-09-17 Astra Pharma Prod Novel process
CA2624533A1 (en) * 2005-10-06 2007-04-12 Innate Pharma Phosphoantigen salts of organic bases and methods for their crystallization
JP5363045B2 (ja) * 2008-07-24 2013-12-11 大八化学工業株式会社 ホスホン酸の製造方法
WO2016114818A1 (en) 2015-01-14 2016-07-21 The Medicines Company Pharmaceutical formulations comprising high purity cangrelor and methods for preparing and using the same
CN111647016A (zh) * 2020-07-10 2020-09-11 成都纽瑞特医疗科技股份有限公司 羟基亚甲基二膦酸盐的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3251907A (en) * 1962-08-23 1966-05-17 Procter & Gamble Method for preparing tetra-secondary alkyl methylenediphosphonates
CA777769A (en) 1963-03-18 1968-02-06 H. Roy Clarence Substituted methylene diphosphonic acid compounds and detergent compositions
JPS54125777A (en) 1978-03-20 1979-09-29 Kao Corp Bleaching composition
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche
US4478763A (en) * 1982-10-20 1984-10-23 Univ. Of Southern California Process for preparing alpha-fluorinated alkanediphosphonates
JPS61123709A (ja) * 1984-11-19 1986-06-11 Nippon Soken Inc 排気ガス微粒子浄化機能を有する内燃機関の制御装置
US4689123A (en) * 1986-12-23 1987-08-25 The Dow Chemical Company Novel tetraphosphonic acid compounds, intermediates and a process for their production
FI83421C (fi) * 1989-06-21 1991-07-10 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt anvaendbara metylenbisfosfonsyraderivat.
FI83657C (fi) * 1989-09-08 1991-08-12 Huhtamaeki Oy Foerfarande foer framstaellning av metylenbisfosfonsyror.
FI89366C (fi) 1990-12-20 1993-09-27 Leiras Oy Foerfarande foer framstaellning av nya farmakologiskt anvaendbara metylenbisfosfonsyraderivat
DK0683789T3 (da) 1993-02-10 1998-02-09 Astra Pharma Prod N-alkyl-2-substituerede ATP-analoger
EP0742279A1 (en) 1995-05-10 1996-11-13 The Procter & Gamble Company Acidic aqueous liquid compositions
SE9701219D0 (sv) 1997-04-04 1997-04-04 Astra Pharma Prod New compounds
FI109088B (fi) 1997-09-19 2002-05-31 Leiras Oy Tabletti ja menetelmä sen valmistamiseksi
SE9903345D0 (sv) * 1999-09-17 1999-09-17 Astra Pharma Prod Novel process

Also Published As

Publication number Publication date
US6657076B1 (en) 2003-12-02
HK1045696B (zh) 2003-11-21
CA2383829C (en) 2009-01-20
US7288673B2 (en) 2007-10-30
BR0014057A (pt) 2002-05-21
ES2200921T3 (es) 2004-03-16
AU771628B2 (en) 2004-04-01
AR029393A1 (es) 2003-06-25
JP2003509517A (ja) 2003-03-11
MY119965A (en) 2005-08-30
DE60003323T2 (de) 2004-04-29
PT1216253E (pt) 2003-10-31
US20040171870A1 (en) 2004-09-02
ATE242778T1 (de) 2003-06-15
WO2001021629A1 (en) 2001-03-29
KR20020029135A (ko) 2002-04-17
JP4881524B2 (ja) 2012-02-22
EP1216253A1 (en) 2002-06-26
DE60003323D1 (de) 2003-07-17
NO20021269D0 (no) 2002-03-14
NO331532B1 (no) 2012-01-23
HK1045696A1 (en) 2002-12-06
KR100776105B1 (ko) 2007-11-15
NZ517552A (en) 2003-09-26
IL148442A0 (en) 2002-09-12
CN1371383A (zh) 2002-09-25
AU7027000A (en) 2001-04-24
CA2383829A1 (en) 2001-03-29
ZA200201661B (en) 2003-08-27
CN1150200C (zh) 2004-05-19
NO20021269L (no) 2002-03-14
IL148442A (en) 2005-08-31
TWI274057B (en) 2007-02-21
IL168246A (en) 2010-05-17
EP1216253B1 (en) 2003-06-11
CO5231228A1 (es) 2002-12-27
SE9903345D0 (sv) 1999-09-17

Similar Documents

Publication Publication Date Title
DK1163207T3 (da) Forbedret fremgangsmåde til fremstillingen af ikke-hygroskopiske salte af L(-)-carnitin
DK1275387T3 (da) Fremgangsmåde til fremstilling af farmaceutiske præparater af fenofibrat med höj biologisk tilgængelighed
DK1038008T3 (da) Fremgangsmåde til fremstilling af EGIII-lignende enzymer
IS6724A (is) Aðferð til framleiðslu á N-arýl-anþranilískum sýrum og afleiðum þeirra
IS5982A (is) Aðferð til framleiðslu á 5-sýanóþalíði
DK1165576T3 (da) Fremgangsmåde til fremstilling af amin-platin-komplekser
DK1726658T3 (da) Fremgangsmåde til fremstilling af dihydroxyestere og derivater deraf
DK0775100T3 (da) Fremgangsmåde til fremstilling af trifluorethylen
EE04234B1 (et) L-fenüülefriinvesinikkloriidi valmistamise meetod
DK1098866T3 (da) Fremgangsmåde til fremstilling af ortho-alkylerede benzoesyrederivater
DK1027315T3 (da) Fremgangsmåde til fremstilling af n-butanol
DK1028960T3 (da) Fremgangsmåde til fremstilling af thiazolidinedion
DK0946531T3 (da) Fremgangsmåde til fremstilling af thiazol-derivater
DK1216253T3 (da) Fremgangsmåde til fremstilling af methylendiphosphonsyrer og salte deraf
DK1216226T3 (da) Fremgangsmåde til fremstilling af phenyleddikesyrederivater
DK0811689T3 (da) Fremgangsmåder til fremstilling af clavulansyre og/eller dets salte
DK0946514T3 (da) Fremgangsmåde til fremstilling af n-substituerede 3-hydroxypyrazoler
DK0864564T3 (da) Særlig fremgangsmåde til fremstillingen af alfa-bromlactamderivater
DK0927766T3 (da) Enzymatisk fremgangsmåde til fremstilling af (S)-cyanhydriner
DK1339723T3 (da) Fremgangsmåde og ester derivater anvendelige til fremstilling af cefalosporiner
DK0971931T3 (da) Fremgangsmåde itl debenzylering af dibenzylbiotin
DK1203000T3 (da) Fremgangsmåde til fremstilling af phosphonomethylglycin
DK0864653T3 (da) Fremgangsmåde til fremstilling af 4-(4-(4-(hydroxydiphenyl)-1-piperidinyl)-1-hydroxybutyl)-alfa,alfa-dimethylphenyleddikesyre og phosphorylerede derivater deraf
DK1240173T3 (da) Fremgangsmåde til fremstilling af N-phosphonomethylglycin
DK1265856T3 (da) Hidtil ukendt fremgangsmåde til fremstillingen af alpha-(2,4-disulfophenyl)-N-tert-butylnitron og farmaceutisk acceptable salte deraf