DK1200577T3 - In vitro-udvælgelse og eventuel identifikation af polypeptider ved anvendelse af fastunderlagsbærere - Google Patents

In vitro-udvælgelse og eventuel identifikation af polypeptider ved anvendelse af fastunderlagsbærere

Info

Publication number
DK1200577T3
DK1200577T3 DK00946180T DK00946180T DK1200577T3 DK 1200577 T3 DK1200577 T3 DK 1200577T3 DK 00946180 T DK00946180 T DK 00946180T DK 00946180 T DK00946180 T DK 00946180T DK 1200577 T3 DK1200577 T3 DK 1200577T3
Authority
DK
Denmark
Prior art keywords
library
fusion protein
polypeptides
solid support
vitro selection
Prior art date
Application number
DK00946180T
Other languages
English (en)
Inventor
Per-Ake Nygren
Olof Nord
Mathias Uhlen
Original Assignee
Affibody Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affibody Ab filed Critical Affibody Ab
Application granted granted Critical
Publication of DK1200577T3 publication Critical patent/DK1200577T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK00946180T 1999-07-20 2000-07-20 In vitro-udvælgelse og eventuel identifikation af polypeptider ved anvendelse af fastunderlagsbærere DK1200577T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9917027.6A GB9917027D0 (en) 1999-07-20 1999-07-20 In vitro selection and optional identification of polypeptides using solid support carriers
PCT/GB2000/002809 WO2001005808A2 (en) 1999-07-20 2000-07-20 In vitro selection and optional identification of polypeptides using solid support carriers

Publications (1)

Publication Number Publication Date
DK1200577T3 true DK1200577T3 (da) 2007-06-11

Family

ID=10857605

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00946180T DK1200577T3 (da) 1999-07-20 2000-07-20 In vitro-udvælgelse og eventuel identifikation af polypeptider ved anvendelse af fastunderlagsbærere

Country Status (13)

Country Link
US (2) US6955877B1 (da)
EP (2) EP1826270A1 (da)
JP (1) JP2003505041A (da)
AT (1) ATE353963T1 (da)
AU (1) AU761985B2 (da)
CA (1) CA2379143A1 (da)
DE (1) DE60033402T2 (da)
DK (1) DK1200577T3 (da)
ES (1) ES2279761T3 (da)
GB (1) GB9917027D0 (da)
NO (1) NO20020276L (da)
WO (1) WO2001005808A2 (da)
ZA (1) ZA200200194B (da)

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US8178316B2 (en) 2006-06-29 2012-05-15 President And Fellows Of Harvard College Evaluating proteins
US8906700B2 (en) 2007-11-06 2014-12-09 Ambergen, Inc. Methods and compositions for phototransfer
US8932879B2 (en) * 2007-11-06 2015-01-13 Ambergen, Inc. Methods and compounds for phototransfer
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WO2010086400A1 (en) 2009-01-30 2010-08-05 Atlas Antibodies Ab Combination treatment of breast cancer
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JP5677943B2 (ja) 2008-06-05 2015-02-25 アフィボディ・アーベーＡｆｆｉｂｏｄｙ Ａｂ ポリペプチド
AU2009282413B2 (en) 2008-08-11 2014-07-17 Nektar Therapeutics Multi-arm polymeric alkanoate conjugates
EP2161577A1 (en) 2008-09-01 2010-03-10 Atlas Antibodies AB ANLN protein
EP2172477A1 (en) 2008-10-06 2010-04-07 Atlas Antibodies AB Epitopes derived from SATB2 and uses thereof
AU2009339802B2 (en) 2009-02-16 2014-07-24 Atlas Antibodies Ab RBM3 as a marker for malignant melanoma prognosis
EP2524928A1 (en) 2011-05-18 2012-11-21 Atlas Antibodies AB RBM3 in bladder cancer
EP2241889A1 (en) 2009-04-16 2010-10-20 Atlas Antibodies AB RBM3 protein in colorectal cancer prognostics
EP2293070A1 (en) 2009-08-13 2011-03-09 Atlas Antibodies AB Means and methods for ovarian cancer prognosis
EP2259059A1 (en) 2009-05-29 2010-12-08 Atlas Antibodies AB Means and methods for ovarian cancer prognosis
EP2315028A1 (en) 2009-10-26 2011-04-27 Atlas Antibodies AB PODXL protein in colorectal cancer
EP2390665A1 (en) 2010-05-27 2011-11-30 Atlas Antibodies AB Prostate cancer biomarkers
CA2815267C (en) 2010-10-27 2019-06-25 Spiber Technologies Ab Spider silk fusion protein structures for binding to an organic target
US10894087B2 (en) 2010-12-22 2021-01-19 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
WO2012088422A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
WO2012110824A1 (en) 2011-02-18 2012-08-23 Astrazeneca Ab Binding agents with specificity for a nucleic acid modification
WO2012166555A1 (en) 2011-05-27 2012-12-06 Nektar Therapeutics Water - soluble polymer - linked binding moiety and drug compounds
EP2544007A1 (en) 2011-07-07 2013-01-09 Atlas Antibodies AB Biomarker of renal impairment
EP2573566A1 (en) 2011-09-20 2013-03-27 Atlas Antibodies AB RBM3 in prostate cancer prognostics
EP2602622A1 (en) 2011-12-07 2013-06-12 Atlas Antibodies AB Prediction of response to platinum-based therapy
AU2012324020A1 (en) 2011-12-30 2013-07-18 Grifols, S.A. Method for purifying Factor VIII
EP2809783A2 (en) * 2012-02-02 2014-12-10 Invenra, Inc. High throughput screen for biologically active polypeptides
CN104470607B (zh) 2012-05-02 2017-04-05 思百博技术股份公司 作为亲和配体的掺入有免疫球蛋白片段的蜘蛛丝融合蛋白结构
EP2844360B1 (en) 2012-05-02 2018-12-19 Spiber Technologies AB Spider silk fusion protein structures without repetitive fragment for binding to an organic target
EP2746768A1 (en) 2012-12-20 2014-06-25 Atlas Antibodies AB Podxl in bladder cancer
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JP3693352B2 (ja) * 1997-06-13 2005-09-07 アフィメトリックス インコーポレイテッド プローブアレイを使用して、遺伝子多型性を検出し、対立遺伝子発現をモニターする方法
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US7435549B1 (en) * 1997-11-17 2008-10-14 Micromet Ag Method of identifying binding site domains that retain the capacity of binding to an epitope
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Also Published As

Publication number Publication date
ES2279761T3 (es) 2007-09-01
NO20020276L (no) 2002-03-15
CA2379143A1 (en) 2001-01-25
US20060035265A1 (en) 2006-02-16
DE60033402D1 (de) 2007-03-29
NO20020276D0 (no) 2002-01-18
ZA200200194B (en) 2003-06-25
JP2003505041A (ja) 2003-02-12
AU6005300A (en) 2001-02-05
ATE353963T1 (de) 2007-03-15
US6955877B1 (en) 2005-10-18
GB9917027D0 (en) 1999-09-22
DE60033402T2 (de) 2007-11-29
WO2001005808A2 (en) 2001-01-25
EP1200577B1 (en) 2007-02-14
EP1200577A2 (en) 2002-05-02
AU761985B2 (en) 2003-06-12
EP1826270A1 (en) 2007-08-29
WO2001005808A3 (en) 2001-08-02

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