ATE313626T1 - Mu-1, ein mitglied der zytokinrezeptor-familie - Google Patents
Mu-1, ein mitglied der zytokinrezeptor-familieInfo
- Publication number
- ATE313626T1 ATE313626T1 AT99911454T AT99911454T ATE313626T1 AT E313626 T1 ATE313626 T1 AT E313626T1 AT 99911454 T AT99911454 T AT 99911454T AT 99911454 T AT99911454 T AT 99911454T AT E313626 T1 ATE313626 T1 AT E313626T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor family
- cytokine receptor
- disclosed
- fragments
- proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/040,005 US6057128A (en) | 1998-03-17 | 1998-03-17 | MU-1, member of the cytokine receptor family |
| PCT/US1999/005854 WO1999047675A1 (en) | 1998-03-17 | 1999-03-17 | Mu-1, member of the cytokine receptor family |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE313626T1 true ATE313626T1 (de) | 2006-01-15 |
Family
ID=21908554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99911454T ATE313626T1 (de) | 1998-03-17 | 1999-03-17 | Mu-1, ein mitglied der zytokinrezeptor-familie |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US6057128A (de) |
| EP (4) | EP0994947B1 (de) |
| JP (3) | JP2001527423A (de) |
| AT (1) | ATE313626T1 (de) |
| AU (1) | AU758824B2 (de) |
| DE (1) | DE69929019T2 (de) |
| DK (1) | DK0994947T3 (de) |
| ES (1) | ES2253879T3 (de) |
| WO (1) | WO1999047675A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057128A (en) * | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
| US7198789B2 (en) * | 1998-03-17 | 2007-04-03 | Genetics Institute, Llc | Methods and compositions for modulating interleukin-21 receptor activity |
| US7189400B2 (en) | 1998-03-17 | 2007-03-13 | Genetics Institute, Llc | Methods of treatment with antagonists of MU-1 |
| EP1088831A4 (de) * | 1998-06-24 | 2003-01-02 | Chugai Pharmaceutical Co Ltd | Hämopoietin-rezeptor proteine |
| AU5104799A (en) * | 1998-08-04 | 2000-02-28 | Regeneron Pharmaceuticals, Inc. | Novel orphan cytokine receptors |
| US6803451B2 (en) | 1998-09-23 | 2004-10-12 | Zymogenetics, Inc. | Cytokine receptor zalpha11 polypeptides |
| US6576744B1 (en) * | 1998-09-23 | 2003-06-10 | Zymogenetics, Inc. | Cytokine receptor zalpha11 |
| AU2004203069B2 (en) * | 1998-09-23 | 2008-06-12 | Zymogenetics Inc. | Cytokine Receptor Zalpha11 |
| EP1115862B1 (de) * | 1998-09-23 | 2009-07-15 | ZymoGenetics, Inc. | Cytokinerezeptor zalpha11 |
| ATE377076T1 (de) * | 1999-03-09 | 2007-11-15 | Zymogenetics Inc | Humanes cytokin als ligand des zalpha rezeptors und dessen verwendungen |
| US6307024B1 (en) * | 1999-03-09 | 2001-10-23 | Zymogenetics, Inc. | Cytokine zalpha11 Ligand |
| US20020090680A1 (en) * | 1999-05-18 | 2002-07-11 | Millennium Pharmaceuticals, Inc. | Novel IL-9/IL-2 receptor-like molecules and uses thereof |
| WO2000069880A1 (en) * | 1999-05-18 | 2000-11-23 | Millennium Pharmaceuticals, Inc. | Il-9/il-2 receptor-like molecules and uses thereof |
| WO2001077171A2 (en) * | 2000-04-05 | 2001-10-18 | Zymogenetics, Inc. | Soluble zalpha11 cytokine receptors |
| EP1787997A1 (de) * | 2000-05-11 | 2007-05-23 | Genetics Institute, LLC | MU-1, ein Mitglied der cytokine rezeptor Familie |
| EP1432431B1 (de) * | 2001-10-04 | 2017-05-10 | Genetics Institute LLC | Verfahren und zusammensetzungen zur modulierung der wirkung des interleukin-21 |
| US20040016010A1 (en) * | 2002-04-17 | 2004-01-22 | Marion Kasaian | IL-21 receptor knockout animal and methods of use thereof |
| CA2487133A1 (en) * | 2002-06-07 | 2003-12-18 | Zymogenetics, Inc. | Use of il-21 in cancer and other therapeutic applications |
| KR20050037552A (ko) * | 2002-07-15 | 2005-04-22 | 와이어쓰 | T 헬퍼(th) 세포 발생 및 기능을 조절하는 방법 및조성물 |
| US20070092485A1 (en) * | 2002-11-15 | 2007-04-26 | Zymogenetics, Inc. | Cytokine zalpha11 ligand |
| JP4664684B2 (ja) | 2002-12-13 | 2011-04-06 | ザイモジェネティクス, インコーポレイテッド | 原核生物宿主におけるil−21の生産 |
| CA2518371A1 (en) * | 2003-03-14 | 2004-09-30 | Wyeth | Antibodies against human il-21 receptor and uses therefor |
| MXPA05010035A (es) * | 2003-03-21 | 2005-11-17 | Wyeth Corp | Tratamiento de desordenes inmunologicos usando agonistas de interleucina-21/receptor de interleucina-21. |
| US7276478B2 (en) * | 2003-09-25 | 2007-10-02 | Zymogenetics, Inc. | Methods of treating autoimmune diseases using IL-21 |
| WO2005113001A1 (en) * | 2004-05-20 | 2005-12-01 | Zymogenetics, Inc. | Methods of treating cancer using il-21 and monoclonal antibody therapy |
| US20070111941A1 (en) * | 2004-06-09 | 2007-05-17 | Zymogenetics, Inc. | Cytokine receptor zalpha11 |
| CA2574848A1 (en) * | 2004-08-05 | 2006-12-21 | Wyeth | Antagonizing interleukin-21 receptor activity |
| GT200600148A (es) * | 2005-04-14 | 2006-11-22 | Metodos para el tratamiento y la prevencion de fibrosis | |
| EP1960433A2 (de) * | 2005-11-28 | 2008-08-27 | Zymogenetics, Inc. | Il-21 rezeptor antagonisten |
| AU2006340750B2 (en) | 2005-11-28 | 2013-03-07 | Zymogenetics, Inc. | IL-21 antagonists |
| EP2217268B1 (de) * | 2007-12-07 | 2016-05-04 | ZymoGenetics, Inc. | Monoklonale antii-human-il-21-antikörper |
| CA2725154A1 (en) * | 2008-05-23 | 2009-11-26 | Wyeth Llc | Methods of treatment utilizing binding proteins of the interleukin-21 receptor |
| AR071885A1 (es) * | 2008-05-23 | 2010-07-21 | Wyeth Corp | Proteinas de union al receptor de interleuquina 21 |
| US12012441B2 (en) | 2020-10-26 | 2024-06-18 | Neptune Biosciences Llc | Engineered human IL-21 cytokines and methods for using the same |
Family Cites Families (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4737323A (en) | 1986-02-13 | 1988-04-12 | Liposome Technology, Inc. | Liposome extrusion method |
| US5011912A (en) | 1986-12-19 | 1991-04-30 | Immunex Corporation | Hybridoma and monoclonal antibody for use in an immunoaffinity purification system |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| EP0325224B1 (de) | 1988-01-22 | 1996-07-31 | ZymoGenetics, Inc. | Verfahren zur Herstellung von sekretierten Rezeptoranalogen |
| US5750375A (en) | 1988-01-22 | 1998-05-12 | Zymogenetics, Inc. | Methods of producing secreted receptor analogs and biologically active dimerized polypeptide fusions |
| US5567584A (en) | 1988-01-22 | 1996-10-22 | Zymogenetics, Inc. | Methods of using biologically active dimerized polypeptide fusions to detect PDGF |
| US6018026A (en) | 1988-01-22 | 2000-01-25 | Zymogenetics, Inc. | Biologically active dimerized and multimerized polypeptide fusions |
| US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| US6406697B1 (en) | 1989-02-23 | 2002-06-18 | Genentech, Inc. | Hybrid immunoglobulins |
| US5098833A (en) | 1989-02-23 | 1992-03-24 | Genentech, Inc. | DNA sequence encoding a functional domain of a lymphocyte homing receptor |
| US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| US5216131A (en) | 1989-02-23 | 1993-06-01 | Genentech, Inc. | Lymphocyte homing receptors |
| GB8927546D0 (en) | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
| US6136310A (en) | 1991-07-25 | 2000-10-24 | Idec Pharmaceuticals Corporation | Recombinant anti-CD4 antibodies for human therapy |
| US5447851B1 (en) | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
| CA2196200A1 (en) | 1994-07-29 | 1996-02-15 | Michael Joseph Browne | Novel compounds |
| FR2742156A1 (fr) | 1995-12-06 | 1997-06-13 | Sanofi Sa | Polypeptide recepteur de l'il-13 |
| US5710023A (en) | 1996-03-01 | 1998-01-20 | Genetics Institute, Inc. | IL-13 cytokine receptor chain |
| AU2326097A (en) | 1996-03-13 | 1997-10-01 | Zymogenetics Inc. | Cytokine-receptor expressed in testis cells |
| WO1997047741A1 (en) | 1996-06-12 | 1997-12-18 | Smithkline Beecham Corporation | Hr-1 receptor |
| WO1997047742A1 (en) | 1996-06-12 | 1997-12-18 | Smithkline Beecham Corporation | Hr-1 receptor |
| EP0812913A3 (de) * | 1996-06-12 | 1999-08-04 | Smithkline Beecham Corporation | HR1 Rezeptor, ein Rezeptor der Zytokinrezeptor-Familie |
| WO1998010638A1 (en) | 1996-09-10 | 1998-03-19 | Amrad Operations Pty. Ltd. | Therapeutic molecules |
| AUPO224696A0 (en) | 1996-09-11 | 1996-10-03 | Amrad Operations Pty. Limited | A novel haemopoietin receptor and genetic sequences encoding same |
| AU5733898A (en) * | 1997-01-16 | 1998-08-07 | Genetics Institute Inc. | Member of the hematopoietin receptor superfamily |
| US20010025022A1 (en) | 1997-11-26 | 2001-09-27 | Kikly Kristine Kay | Hnovilr |
| US7198789B2 (en) | 1998-03-17 | 2007-04-03 | Genetics Institute, Llc | Methods and compositions for modulating interleukin-21 receptor activity |
| US7189400B2 (en) | 1998-03-17 | 2007-03-13 | Genetics Institute, Llc | Methods of treatment with antagonists of MU-1 |
| US6057128A (en) | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
| US6509057B2 (en) * | 1998-04-01 | 2003-01-21 | Sumitomo Osaka Cement, Co., Ltd. | Antibacterial, antifungal or antialgal article and process for producing same |
| EP1088831A4 (de) | 1998-06-24 | 2003-01-02 | Chugai Pharmaceutical Co Ltd | Hämopoietin-rezeptor proteine |
| AU5104799A (en) | 1998-08-04 | 2000-02-28 | Regeneron Pharmaceuticals, Inc. | Novel orphan cytokine receptors |
| EP1115862B1 (de) | 1998-09-23 | 2009-07-15 | ZymoGenetics, Inc. | Cytokinerezeptor zalpha11 |
| US6576744B1 (en) | 1998-09-23 | 2003-06-10 | Zymogenetics, Inc. | Cytokine receptor zalpha11 |
| US6803451B2 (en) | 1998-09-23 | 2004-10-12 | Zymogenetics, Inc. | Cytokine receptor zalpha11 polypeptides |
| WO2000027882A1 (en) | 1998-11-06 | 2000-05-18 | Smithkline Beecham Corporation | Hnovilr |
| US6307024B1 (en) | 1999-03-09 | 2001-10-23 | Zymogenetics, Inc. | Cytokine zalpha11 Ligand |
| ATE377076T1 (de) | 1999-03-09 | 2007-11-15 | Zymogenetics Inc | Humanes cytokin als ligand des zalpha rezeptors und dessen verwendungen |
| US20020090680A1 (en) | 1999-05-18 | 2002-07-11 | Millennium Pharmaceuticals, Inc. | Novel IL-9/IL-2 receptor-like molecules and uses thereof |
| WO2000069880A1 (en) | 1999-05-18 | 2000-11-23 | Millennium Pharmaceuticals, Inc. | Il-9/il-2 receptor-like molecules and uses thereof |
| MXPA02005058A (es) | 1999-11-18 | 2002-11-07 | Schering Corp | Proteinas de mamiferos receptoras, reactivos y metodos relacionados. |
| WO2001046261A1 (en) | 1999-12-23 | 2001-06-28 | Zymogenetics, Inc. | Method for treating inflammation |
| WO2001077171A2 (en) | 2000-04-05 | 2001-10-18 | Zymogenetics, Inc. | Soluble zalpha11 cytokine receptors |
| DE10019727A1 (de) * | 2000-04-20 | 2001-10-25 | Alcatel Sa | Netzwerkserver |
| EP1787997A1 (de) | 2000-05-11 | 2007-05-23 | Genetics Institute, LLC | MU-1, ein Mitglied der cytokine rezeptor Familie |
| JP2002157737A (ja) * | 2000-05-12 | 2002-05-31 | Tdk Corp | 光記録方法および光記録媒体 |
| US6680563B2 (en) * | 2001-06-27 | 2004-01-20 | Thomson Licensing S.A. | Color picture tube having a low expansion tension mask attached to a higher expansion frame |
| US6719302B2 (en) * | 2001-07-02 | 2004-04-13 | Vertex, Inc. | Symmetrical gasket for a pipe joint with increased surface contact |
| EP1432431B1 (de) | 2001-10-04 | 2017-05-10 | Genetics Institute LLC | Verfahren und zusammensetzungen zur modulierung der wirkung des interleukin-21 |
| ES2334338T3 (es) | 2001-11-05 | 2010-03-09 | Zymogenetics, Inc. | Antagonistas de il-21. |
| US20040016010A1 (en) | 2002-04-17 | 2004-01-22 | Marion Kasaian | IL-21 receptor knockout animal and methods of use thereof |
| KR20050037552A (ko) | 2002-07-15 | 2005-04-22 | 와이어쓰 | T 헬퍼(th) 세포 발생 및 기능을 조절하는 방법 및조성물 |
| CA2518371A1 (en) | 2003-03-14 | 2004-09-30 | Wyeth | Antibodies against human il-21 receptor and uses therefor |
| MXPA05010035A (es) | 2003-03-21 | 2005-11-17 | Wyeth Corp | Tratamiento de desordenes inmunologicos usando agonistas de interleucina-21/receptor de interleucina-21. |
| AU2005244942A1 (en) | 2004-05-19 | 2005-12-01 | Wyeth | Modulation of immunoglobulin production and atopic disorders |
| CA2574848A1 (en) | 2004-08-05 | 2006-12-21 | Wyeth | Antagonizing interleukin-21 receptor activity |
| GT200600148A (es) | 2005-04-14 | 2006-11-22 | Metodos para el tratamiento y la prevencion de fibrosis | |
| WO2009100035A2 (en) | 2008-02-01 | 2009-08-13 | Wyeth | Interleukin-21 (il-21) and il-21 receptor (il-21r) modulation of regulatory t cells and forkhead box p3 (foxp3) |
| AR071885A1 (es) | 2008-05-23 | 2010-07-21 | Wyeth Corp | Proteinas de union al receptor de interleuquina 21 |
| CA2725154A1 (en) | 2008-05-23 | 2009-11-26 | Wyeth Llc | Methods of treatment utilizing binding proteins of the interleukin-21 receptor |
-
1998
- 1998-03-17 US US09/040,005 patent/US6057128A/en not_active Expired - Lifetime
-
1999
- 1999-03-17 ES ES99911454T patent/ES2253879T3/es not_active Expired - Lifetime
- 1999-03-17 WO PCT/US1999/005854 patent/WO1999047675A1/en not_active Ceased
- 1999-03-17 EP EP99911454A patent/EP0994947B1/de not_active Expired - Lifetime
- 1999-03-17 AT AT99911454T patent/ATE313626T1/de active
- 1999-03-17 JP JP54728399A patent/JP2001527423A/ja not_active Withdrawn
- 1999-03-17 EP EP05112429A patent/EP1681348A1/de not_active Withdrawn
- 1999-03-17 DE DE69929019T patent/DE69929019T2/de not_active Expired - Lifetime
- 1999-03-17 EP EP10167168A patent/EP2228448A1/de not_active Withdrawn
- 1999-03-17 DK DK99911454T patent/DK0994947T3/da active
- 1999-03-17 AU AU30093/99A patent/AU758824B2/en not_active Ceased
- 1999-03-17 EP EP05112423A patent/EP1688495A1/de not_active Withdrawn
-
2007
- 2007-12-17 US US11/957,891 patent/US7705123B2/en not_active Expired - Fee Related
-
2009
- 2009-10-02 JP JP2009230370A patent/JP2010057489A/ja active Pending
-
2010
- 2010-01-28 US US12/695,485 patent/US7994292B2/en not_active Expired - Fee Related
-
2013
- 2013-04-25 JP JP2013093025A patent/JP2013188214A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP2228448A1 (de) | 2010-09-15 |
| US7705123B2 (en) | 2010-04-27 |
| JP2001527423A (ja) | 2001-12-25 |
| US20080167241A1 (en) | 2008-07-10 |
| AU3009399A (en) | 1999-10-11 |
| AU758824B2 (en) | 2003-04-03 |
| EP1681348A1 (de) | 2006-07-19 |
| JP2010057489A (ja) | 2010-03-18 |
| EP1688495A1 (de) | 2006-08-09 |
| ES2253879T3 (es) | 2006-06-01 |
| JP2013188214A (ja) | 2013-09-26 |
| DE69929019T2 (de) | 2006-08-03 |
| WO1999047675A1 (en) | 1999-09-23 |
| EP0994947B1 (de) | 2005-12-21 |
| US7994292B2 (en) | 2011-08-09 |
| DK0994947T3 (da) | 2006-04-18 |
| US20100130729A1 (en) | 2010-05-27 |
| DE69929019D1 (de) | 2006-01-26 |
| EP0994947A1 (de) | 2000-04-26 |
| US6057128A (en) | 2000-05-02 |
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