DK1194161T3 - Stabile faktor VIII-sammensatninger - Google Patents

Stabile faktor VIII-sammensatninger

Info

Publication number
DK1194161T3
DK1194161T3 DK00948452T DK00948452T DK1194161T3 DK 1194161 T3 DK1194161 T3 DK 1194161T3 DK 00948452 T DK00948452 T DK 00948452T DK 00948452 T DK00948452 T DK 00948452T DK 1194161 T3 DK1194161 T3 DK 1194161T3
Authority
DK
Denmark
Prior art keywords
factor viii
stable factor
viii compositions
compositions
stable
Prior art date
Application number
DK00948452T
Other languages
Danish (da)
English (en)
Inventor
Marianne Mikaelsson
Helena Sandberg
Original Assignee
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27354553&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1194161(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE9902685A external-priority patent/SE9902685D0/xx
Priority claimed from SE0001743A external-priority patent/SE0001743D0/xx
Application filed by Biovitrum Ab filed Critical Biovitrum Ab
Application granted granted Critical
Publication of DK1194161T3 publication Critical patent/DK1194161T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK00948452T 1999-07-13 2000-07-07 Stabile faktor VIII-sammensatninger DK1194161T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9902685A SE9902685D0 (sv) 1999-07-13 1999-07-13 Stable protein compositions
US14682899P 1999-08-02 1999-08-02
SE0001743A SE0001743D0 (sv) 2000-05-11 2000-05-11 Stable protein compositions II

Publications (1)

Publication Number Publication Date
DK1194161T3 true DK1194161T3 (da) 2006-02-13

Family

ID=27354553

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00948452T DK1194161T3 (da) 1999-07-13 2000-07-07 Stabile faktor VIII-sammensatninger

Country Status (14)

Country Link
US (1) US6599724B1 (xx)
EP (1) EP1194161B1 (xx)
JP (1) JP4674021B2 (xx)
AR (1) AR024735A1 (xx)
AT (1) ATE310533T1 (xx)
AU (1) AU780415B2 (xx)
CA (1) CA2378751C (xx)
CY (1) CY1104986T1 (xx)
DE (1) DE60024268T2 (xx)
DK (1) DK1194161T3 (xx)
ES (1) ES2252028T3 (xx)
NO (1) NO330048B1 (xx)
NZ (1) NZ516400A (xx)
WO (1) WO2001003726A1 (xx)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2541470T3 (es) 1999-02-22 2015-07-20 University Of Connecticut Formulaciones de factor VIII libres de albúmina
HUP0402315A3 (en) 2001-12-21 2009-03-30 Novo Nordisk Healthcare Ag Liquid composition of factor vii polypeptides
KR20040065278A (ko) * 2001-12-21 2004-07-21 노보 노르디스크 에이/에스 변경된 인자 ⅶ 폴리펩티드의 액체 조성물
GB0202633D0 (en) * 2002-02-05 2002-03-20 Delta Biotechnology Ltd Stabilization of protein preparations
GB0207092D0 (en) 2002-03-26 2002-05-08 Sod Conseils Rech Applic Stable pharmaceutical composition containing factor VIII
US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
DK2283856T3 (da) 2002-06-21 2017-11-20 Novo Nordisk Healthcare Ag Stabiliserede, faste sammensætninger af Faktor VIIa-polypeptider
DE60314667T3 (de) † 2002-12-27 2019-12-05 Japan Cash Machine Co., Ltd. Optische messvorrichtung zur bestimmung optischer merkmale von wertpapieren
CA2518327A1 (en) * 2003-03-18 2004-09-30 Novo Nordisk Health Care Ag Liquid, aqueous, pharmaceutical compositions of factor vii polypeptides
US7897734B2 (en) * 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
DE602004025100D1 (de) * 2003-05-23 2010-03-04 Novo Nordisk Healthcare Ag Stabilisierung von proteinen in lösung
US7709224B2 (en) 2003-06-03 2010-05-04 Biosante Pharmaceuticals, Inc. Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
US7485291B2 (en) 2003-06-03 2009-02-03 Cell Genesys, Inc. Compositions and methods for generating multiple polypeptides from a single vector using a virus derived peptide cleavage site, and uses thereof
WO2004112828A1 (en) * 2003-06-25 2004-12-29 Novo Nordisk Health Care Ag Liquid composition of factor vii polypeptides
DE602004023848D1 (de) * 2003-07-01 2009-12-10 Novo Nordisk Healthcare Ag Von factor vii polypeptiden
BRPI0413518A (pt) 2003-08-14 2006-10-10 Novo Nordisk Healthcare Ag composição farmacêutica lìquida aquosa, método para preparar e uso da mesma, método para tratar uma sìndrome responsiva ao fator vii, e, recipiente hermético
ES2229931B1 (es) * 2003-10-03 2006-01-16 Grifols, S.A. Composicion liquida bilogicamente estable de fviii, de fvw o del complejo fviii/fvw humanos.
US20050090551A1 (en) * 2003-10-27 2005-04-28 Board Of Trustees Of Southern Illinois University Therapeutic use of methionine for the treatment or prevention of mucositis
WO2005055930A2 (en) * 2003-12-03 2005-06-23 University Of Rochester Recombinant factor viii having increased specific activity
CA2549593C (en) * 2003-12-19 2014-02-11 Novo Nordisk Health Care Ag Stabilised compositions of factor vii polypeptides
US7422875B2 (en) * 2004-07-20 2008-09-09 Board Of Regents Of The University Of Nebraska Compositions and methods for increasing protein production
EP1919498A2 (en) * 2005-08-26 2008-05-14 Maxygen Holdings Ltd. Liquid factor vii composition
FR2908892B1 (fr) * 2006-11-21 2009-02-20 Hyphen Biomed Soc Par Actions Procede pour le dosage chromogenique de l'activite du facteur viii:c et necessaire de dosage chromogenique de l'activite du facteur viii:c,dans les plasmas ou les fractions therapeutiques
CA2703948A1 (en) 2007-11-01 2009-05-07 University Of Rochester Recombinant factor viii having increased stability
PL2574676T3 (pl) 2007-12-27 2017-12-29 Baxalta GmbH Sposoby hodowli komórek
KR101752508B1 (ko) * 2008-11-07 2017-06-29 백스터 인터내셔널 인코포레이티드 제8 인자 제형
GB0915481D0 (en) 2009-09-04 2009-10-07 Arecor Ltd Stable manufacture of factor V111
GB0915480D0 (en) 2009-09-04 2009-10-07 Arecor Ltd Stable formulation of factor viii
MX347503B (es) 2010-11-05 2017-04-26 Baxalta Inc Una variante nueva del factor viii antihemofílico que tiene actividad específica incrementada.
EP2707387B1 (en) * 2011-05-13 2019-12-25 Octapharma AG A method of increasing the productivity of eucaryotic cells in the production of recombinant fviii
JP2014531910A (ja) 2011-10-18 2014-12-04 シーエスエル、リミテッド 再構成後の精製第ｖｉｉｉ因子の安定性を改善するための方法
JP2017509658A (ja) 2014-04-01 2017-04-06 アドヴァンテック・バイオサイエンス・ファルマスーティカ・リミターダ カルシウム添加剤を使用しない第ｖｉｉｉ因子の安定化
CA2944349A1 (en) * 2014-04-01 2015-10-08 Advantech Bioscience Farmaceutica Ltda. Stable factor viii formulations with low sugar-glycine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2593500B2 (ja) 1986-06-24 1997-03-26 ノルデイスク ゲントフテ エー／エス ▲ｖｉｉｉ▼因子フラグメントの凝固活性複合物の製造方法
US5733873A (en) 1992-10-02 1998-03-31 Pharmacia & Upjohn Ab Composition comprising coagulation factor VIII formulation, process for its preparation and use of a surfactant as stabilizer
SE9301581D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Protein formulation
AU7254894A (en) * 1993-07-23 1995-02-20 Baxter International Inc. Activated human factor viii and method of preparation
US5576291A (en) * 1993-09-13 1996-11-19 Baxter International Inc. Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency
ATE356198T1 (de) * 1996-10-11 2007-03-15 Invitrogen Corp Definierte systeme zur kultivieurng epithelialer zellen und anwendung derselben
US5804420A (en) * 1997-04-18 1998-09-08 Bayer Corporation Preparation of recombinant Factor VIII in a protein free medium

Also Published As

Publication number Publication date
DE60024268D1 (de) 2005-12-29
CA2378751A1 (en) 2001-01-18
ATE310533T1 (de) 2005-12-15
NO20020120D0 (no) 2002-01-10
NO330048B1 (no) 2011-02-07
DE60024268T2 (de) 2006-08-03
AU780415B2 (en) 2005-03-17
US6599724B1 (en) 2003-07-29
NZ516400A (en) 2004-02-27
JP2003504345A (ja) 2003-02-04
AR024735A1 (es) 2002-10-23
JP4674021B2 (ja) 2011-04-20
NO20020120L (no) 2002-02-28
WO2001003726A1 (en) 2001-01-18
AU6193300A (en) 2001-01-30
EP1194161A1 (en) 2002-04-10
CY1104986T1 (el) 2009-11-04
EP1194161B1 (en) 2005-11-23
CA2378751C (en) 2012-11-06
ES2252028T3 (es) 2006-05-16

Similar Documents

Publication Publication Date Title
DK1194161T3 (da) Stabile faktor VIII-sammensatninger
DE60025198D1 (de) Stabile biozidale zusammensetzung
AR023440A1 (es) Composiciones antitranspirantes
DE60129705D1 (de) Monoalkylglycerinäther stabile zusammensetzungen
DE60014179D1 (de) Tintenzusammensetzungen
NO20014608L (no) Vekstfremmende sammensetninger
DE60020342D1 (de) Tiefeindringende antimikrobielle zusammensetzungen
IS6120A (is) Lyfjablanda
DE69921991D1 (de) Harzzusammensetzungen
ATE303787T1 (de) Schergelzusammensetzungen
DE60040350D1 (de) Weichspülerzusammensetzungen
ATE372372T1 (de) Zusammensetzungen enthaltend cyclodextrin
ITMI991754A0 (it) Composizioni cosmetiche
ID29785A (id) Komposisi-komposisi sampo
DE60021018D1 (de) Polymerzusammensetzungen
AR028197A1 (es) Composiciones antitranspirantes
NO20004497L (no) Modifisert faktor VIII
ATE257691T1 (de) Schweisshemmende zusammensetzungen
DE60036095D1 (de) Beschreibbare-abwaschbare tapete
ATE369830T1 (de) Schweisshemmende zusammensetzungen
DE60015460D1 (de) Polymerzusammensetzungen
ATE314049T1 (de) Schweisshemmende zusammensetzungen
NO20044305L (no) Stabile farmasoytiske blandinger inneholdende faktor VIII
DE69943245D1 (de) Gaserzeugende zusammensetzung
DE60021259D1 (de) Reinigungsmittelzusammensetzungen