DK1193260T3 - Phenoxazinanaloger til behandling af amyloidosis - Google Patents

Phenoxazinanaloger til behandling af amyloidosis

Info

Publication number
DK1193260T3
DK1193260T3 DK01122733T DK01122733T DK1193260T3 DK 1193260 T3 DK1193260 T3 DK 1193260T3 DK 01122733 T DK01122733 T DK 01122733T DK 01122733 T DK01122733 T DK 01122733T DK 1193260 T3 DK1193260 T3 DK 1193260T3
Authority
DK
Denmark
Prior art keywords
hydrogen
lower alkyl
phenoxazine
amyloidosis
analogues
Prior art date
Application number
DK01122733T
Other languages
Danish (da)
English (en)
Inventor
Corinne Elizab Augelli-Szafran
Yingije Lai
Tomoyuki Yasunaga
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of DK1193260T3 publication Critical patent/DK1193260T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/38—[b, e]-condensed with two six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK01122733T 2000-09-29 2001-09-21 Phenoxazinanaloger til behandling af amyloidosis DK1193260T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23696600P 2000-09-29 2000-09-29

Publications (1)

Publication Number Publication Date
DK1193260T3 true DK1193260T3 (da) 2006-04-10

Family

ID=22891762

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01122733T DK1193260T3 (da) 2000-09-29 2001-09-21 Phenoxazinanaloger til behandling af amyloidosis

Country Status (10)

Country Link
US (1) US20020143012A1 (de)
EP (1) EP1193260B1 (de)
JP (1) JP2002201186A (de)
AT (1) ATE312086T1 (de)
BR (1) BR0104344A (de)
CA (1) CA2357450A1 (de)
DE (1) DE60115569T2 (de)
DK (1) DK1193260T3 (de)
ES (1) ES2253315T3 (de)
MX (1) MXPA01009768A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005013985A1 (en) * 2003-08-07 2005-02-17 Merck Sharp & Dohme Limited Treatment for alzheimer's disease and related conditions
JP2007502798A (ja) * 2003-08-18 2007-02-15 ノバルティス アクチエンゲゼルシャフト 近赤外線造影剤に適する３ｈ−フェノキサジン誘導体、その製造法および使用
GB0410238D0 (en) * 2004-05-07 2004-06-09 Merck Sharp & Dohme Therapeutic agents
CA2668744C (en) * 2006-11-17 2015-09-15 Queen's University At Kingston Compounds and methods for treating protein folding disorders
WO2014032732A1 (de) * 2012-08-28 2014-03-06 Eberhard Karls Universität Tübingen Medizinische Fakultät Halogenierte benzoxazine und ihre verwendung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506197D0 (en) * 1995-03-27 1995-05-17 Hoffmann La Roche Inhibition of tau-tau association.
CA2375551A1 (en) * 1999-06-10 2000-12-21 Warner-Lambert Company Method of inhibiting amyloid protein aggregation and imaging amyloid deposits
YU86801A (sh) * 1999-06-10 2004-07-15 Warner-Lambert Company Izoindol derivati korisni u inhibiciji agregacije amiloidnih proteina i snimanju amiloidnih naslaga

Also Published As

Publication number Publication date
MXPA01009768A (es) 2004-08-12
EP1193260B1 (de) 2005-12-07
DE60115569T2 (de) 2006-08-10
US20020143012A1 (en) 2002-10-03
JP2002201186A (ja) 2002-07-16
ATE312086T1 (de) 2005-12-15
EP1193260A1 (de) 2002-04-03
DE60115569D1 (de) 2006-01-12
BR0104344A (pt) 2003-03-05
ES2253315T3 (es) 2006-06-01
CA2357450A1 (en) 2002-03-29

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