DK1192156T3 - Bispidinforbindelser, som er egnede til behandling af hjertearytmier - Google Patents

Bispidinforbindelser, som er egnede til behandling af hjertearytmier

Info

Publication number
DK1192156T3
DK1192156T3 DK00946588T DK00946588T DK1192156T3 DK 1192156 T3 DK1192156 T3 DK 1192156T3 DK 00946588 T DK00946588 T DK 00946588T DK 00946588 T DK00946588 T DK 00946588T DK 1192156 T3 DK1192156 T3 DK 1192156T3
Authority
DK
Denmark
Prior art keywords
treatment
compounds suitable
cardiac arrhythmias
bispidine compounds
bispidine
Prior art date
Application number
DK00946588T
Other languages
Danish (da)
English (en)
Inventor
Magnus Bjoersne
Marianne Frantsi
Kurt-Juergen Hoffmann
Bengt Ohlsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1192156T3 publication Critical patent/DK1192156T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK00946588T 1999-06-16 2000-06-15 Bispidinforbindelser, som er egnede til behandling af hjertearytmier DK1192156T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9902269A SE9902269D0 (sv) 1999-06-16 1999-06-16 Pharmaceutically active compounds
PCT/SE2000/001252 WO2000076998A1 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
DK1192156T3 true DK1192156T3 (da) 2004-05-17

Family

ID=20416101

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00946588T DK1192156T3 (da) 1999-06-16 2000-06-15 Bispidinforbindelser, som er egnede til behandling af hjertearytmier

Country Status (28)

Country Link
EP (1) EP1192156B1 (no)
JP (1) JP2003502327A (no)
KR (1) KR20020042534A (no)
CN (1) CN1187351C (no)
AR (1) AR024392A1 (no)
AT (1) ATE259809T1 (no)
AU (1) AU762040B2 (no)
BR (1) BR0011667A (no)
CA (1) CA2377395A1 (no)
CZ (1) CZ20014493A3 (no)
DE (1) DE60008377T2 (no)
DK (1) DK1192156T3 (no)
EE (1) EE200100679A (no)
ES (1) ES2214291T3 (no)
HK (1) HK1045689A1 (no)
HU (1) HUP0300244A3 (no)
IL (1) IL146751A0 (no)
IS (1) IS6200A (no)
MX (1) MXPA01012926A (no)
NO (1) NO20016120L (no)
NZ (1) NZ516014A (no)
PL (1) PL353155A1 (no)
PT (1) PT1192156E (no)
SE (1) SE9902269D0 (no)
SK (1) SK18292001A3 (no)
TR (1) TR200103635T2 (no)
WO (1) WO2000076998A1 (no)
ZA (1) ZA200109798B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030302A1 (es) * 2000-07-07 2003-08-20 Astrazeneca Ab Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE3732094A1 (de) * 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) * 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds

Also Published As

Publication number Publication date
ES2214291T3 (es) 2004-09-16
MXPA01012926A (es) 2002-07-30
AR024392A1 (es) 2002-10-02
KR20020042534A (ko) 2002-06-05
JP2003502327A (ja) 2003-01-21
AU6032300A (en) 2001-01-02
CZ20014493A3 (cs) 2002-05-15
SK18292001A3 (sk) 2002-12-03
PT1192156E (pt) 2004-06-30
AU762040B2 (en) 2003-06-19
ZA200109798B (en) 2003-02-28
NZ516014A (en) 2003-06-30
BR0011667A (pt) 2002-04-02
HK1045689A1 (zh) 2002-12-06
WO2000076998A1 (en) 2000-12-21
EP1192156B1 (en) 2004-02-18
IS6200A (is) 2001-12-14
IL146751A0 (en) 2002-07-25
CN1187351C (zh) 2005-02-02
WO2000076998B1 (en) 2001-03-08
SE9902269D0 (sv) 1999-06-16
CN1370165A (zh) 2002-09-18
DE60008377D1 (de) 2004-03-25
TR200103635T2 (tr) 2002-04-22
EE200100679A (et) 2003-02-17
PL353155A1 (en) 2003-10-20
HUP0300244A3 (en) 2003-12-29
HUP0300244A2 (hu) 2003-06-28
NO20016120L (no) 2002-02-18
CA2377395A1 (en) 2000-12-21
ATE259809T1 (de) 2004-03-15
EP1192156A1 (en) 2002-04-03
DE60008377T2 (de) 2004-12-09
NO20016120D0 (no) 2001-12-14

Similar Documents

Publication Publication Date Title
DK1235831T3 (da) Nye oxabispidinforbindelser, der er anvendelige til behandling af hjertearytmier
NO20013559L (no) Aromatiske heterocykliske forbindelser som anti- inflammatoriske midler
EE200200172A (et) Ühendid isheemia ravimiseks
DK1147083T3 (da) Arylpiperazinyl-cyclohexylindolderivater til behandling af depression
DK1147114T3 (da) Hidtil ukendt aralkylaminer af spirofuropyridiner, der er egnede til terapi
NO20002217D0 (no) Cyclopentan-heptansyre, 2-heteroarylalkenylderivater som terapeutiske midler
NO20014412D0 (no) Forbindelser nyttige som anti-inflammatoriske midler
NO20022087L (no) Fremgangsmåte for behandling av diabetes
DK1104420T3 (da) Substituerede 1,8-naphthyridin-4(1H)-oner som phosphodiesterase-4-inhibitorer
NO20022557D0 (no) 2,4-diaminopyrimidinforbindelser nyttige som immunosuppreserende midler
NO990722D0 (no) FremgangsmÕte for behandling av hjertesvikt
NO20031414L (no) Ny oksabispidinforbindelse som er nyttig i behandlingen av hjertearrytmier
DK1434588T3 (da) 2-(amino-3,4-dioxo-1cyclobuten-1-yl)aminoalkylsyrederivater til behandling af smerte
NO20020485L (no) Heterocykliske forbindelser som inhiberer angiogenese
NO20000456D0 (no) Fremgangsmåte for fremstilling av 1,2-dikloretan
DK1192156T3 (da) Bispidinforbindelser, som er egnede til behandling af hjertearytmier
DK1224181T3 (da) Substituerede pyrroler som antiproliferative midler til behandling af cancer
DK1192154T3 (da) Bispidinforbindelser, som er egnede ved behandling af hjertearytmier
NO20020308D0 (no) Fremgangsmåte for fremstilling av epothiolon B og derivater, såvel som mellomprodukter for fremgangsmåten
NO20016117D0 (no) Nye bispidinforbindelser som er nyttige i behandlingen av hjertearytmier
DK1157987T3 (da) S-nitrosothioler som midler til behandling af kredsløbsforstyrrelser
NO20016119D0 (no) Nye bispidinforbindelser som er nyttige i behandlingen av hjertearytmier
IT1338456B1 (it) Procedimento per la preparazione di alchiluree da o ,d-dimetil ditiocarbonato
ITTO980741A0 (it) Procedimento di preparazione di composti del tipo arilamminoalchilidenemalonati.
ITMI992457A0 (it) Procedimento per la preparazione di (s)-n-terbutil-1,2,3,4-tetraidrois ochinolin-3-carbossiammide