DK1157987T3 - S-nitrosothioler som midler til behandling af kredsløbsforstyrrelser - Google Patents
S-nitrosothioler som midler til behandling af kredsløbsforstyrrelserInfo
- Publication number
- DK1157987T3 DK1157987T3 DK00900518T DK00900518T DK1157987T3 DK 1157987 T3 DK1157987 T3 DK 1157987T3 DK 00900518 T DK00900518 T DK 00900518T DK 00900518 T DK00900518 T DK 00900518T DK 1157987 T3 DK1157987 T3 DK 1157987T3
- Authority
- DK
- Denmark
- Prior art keywords
- nitrosothiols
- agents
- treatment
- circulatory disorders
- circulatory
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009900159A ES2147162B1 (es) | 1999-01-27 | 1999-01-27 | "s-nitrosotioles como agentes para el tratamiento de disfunciones circulatorias". |
PCT/ES2000/000019 WO2000044714A1 (es) | 1999-01-27 | 2000-01-19 | S-nitrosotioles como agentes para el tratamiento de disfunciones circulatorias |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1157987T3 true DK1157987T3 (da) | 2003-11-24 |
Family
ID=8307080
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00900518T DK1157987T3 (da) | 1999-01-27 | 2000-01-19 | S-nitrosothioler som midler til behandling af kredsløbsforstyrrelser |
Country Status (37)
Country | Link |
---|---|
US (1) | US6800612B2 (da) |
EP (1) | EP1157987B1 (da) |
JP (1) | JP3795330B2 (da) |
KR (1) | KR100671878B1 (da) |
CN (1) | CN1166631C (da) |
AP (1) | AP1439A (da) |
AT (1) | ATE249428T1 (da) |
AU (1) | AU764725B2 (da) |
BG (1) | BG64983B1 (da) |
BR (1) | BR0007395B1 (da) |
CA (1) | CA2359027C (da) |
CU (1) | CU23098A3 (da) |
CZ (1) | CZ298871B6 (da) |
DE (2) | DE60005154T2 (da) |
DK (1) | DK1157987T3 (da) |
EA (1) | EA003577B1 (da) |
EE (1) | EE04524B1 (da) |
ES (2) | ES2147162B1 (da) |
GB (1) | GB2363604B (da) |
GE (1) | GEP20043220B (da) |
HK (1) | HK1043586A1 (da) |
HR (1) | HRP20010562B1 (da) |
HU (1) | HUP0105203A3 (da) |
ID (1) | ID29777A (da) |
IL (1) | IL144381A (da) |
IS (1) | IS2153B (da) |
MX (1) | MXPA01007570A (da) |
NO (1) | NO326806B1 (da) |
NZ (1) | NZ513162A (da) |
OA (1) | OA11823A (da) |
PL (1) | PL202372B1 (da) |
PT (1) | PT1157987E (da) |
RS (1) | RS50072B (da) |
SI (1) | SI1157987T1 (da) |
TR (1) | TR200102003T2 (da) |
WO (1) | WO2000044714A1 (da) |
ZA (1) | ZA200106182B (da) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2173044B1 (es) * | 2001-03-13 | 2004-01-16 | Lacer Sa | Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones. |
CA2539973A1 (en) * | 2003-09-26 | 2005-04-07 | Nitromed, Inc. | Nitrosated glutamic acid compounds, compositions and methods of use |
EP1939179A1 (en) * | 2006-12-28 | 2008-07-02 | Lacer, S.A. | Stable S-nitrosothiols, method of synthesis and use |
PL2197417T3 (pl) | 2007-10-17 | 2012-08-31 | Pharmagenix Ag | Kompozycja farmaceutyczna zawierająca S-nitrozoglutation i polisacharyd |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US37839A (en) * | 1863-03-03 | Improved spoke-machine | ||
GB1567561A (en) | 1977-01-18 | 1980-05-14 | Ucb Sa | Amino-spiro(oxa-(orthia)cycloalkane-penam) - carboxylic acids |
GB2052497B (en) | 1979-06-25 | 1983-06-29 | Ucb Sa | 6 - amino - spiro - (penam - 2,4' - piperidine) - 3 - carboxylic acid derivatives |
DE3805965A1 (de) | 1988-02-25 | 1989-09-07 | Tamas Geb Szenasi Eszter | Verwendung der pflanze euphorbia hirta l. und ihrer extrakte sowie ihrer wirkstoffe |
US5025001A (en) | 1988-06-15 | 1991-06-18 | Brigham And Women's Hospital | S-nitroso derivatives of ACE inhibitors and the use thereof |
EP0412699B1 (en) * | 1989-08-07 | 1994-04-27 | Takeda Chemical Industries, Ltd. | Nitrosothiol derivatives, their production and use |
ATE145919T1 (de) | 1990-04-26 | 1996-12-15 | Senju Pharma Co | Inhibitor von lebererkrankungen |
US5187305A (en) * | 1990-11-26 | 1993-02-16 | Glaxo Inc. | S-nitroso-N-alkonoylpenicillamines |
AU3071592A (en) | 1991-11-14 | 1993-06-15 | Brigham And Women's Hospital | Nitrosylation of protein sh groups and amino acid residues as a therapeutic modality |
NZ248332A (en) | 1992-08-07 | 1995-01-27 | Sankyo Co | Hiv protease inhibitor and its use |
CA2170772C (en) * | 1993-09-17 | 2005-03-29 | Jonathan Stamler | Use of nitric oxide-adducts to prevent thrombosis on artificial and vascular surfaces |
US5728705A (en) | 1993-10-04 | 1998-03-17 | The Trustees Of Columbia University In The City Of New York | Method of inducing vasorelaxation to treat pulmonary hypertension |
PT726768E (pt) | 1993-11-02 | 2000-11-30 | Us Health | Utilizacao de compostos libertadores de acido nitrico para o fabrico de um medicamento para proteccao na lesao por isquemia-reperfusao |
GB9423868D0 (en) | 1994-11-25 | 1995-01-11 | Wellcome Found | Compounds for use in medicine |
US6627738B2 (en) | 1995-09-15 | 2003-09-30 | Duke University | No-modified hemoglobins and uses therefor |
AU6782198A (en) | 1997-03-27 | 1998-10-20 | Trustees Of Boston University | Novel antiplatelet agent |
-
1999
- 1999-01-27 ES ES009900159A patent/ES2147162B1/es not_active Expired - Fee Related
-
2000
- 2000-01-19 JP JP2000595971A patent/JP3795330B2/ja not_active Expired - Fee Related
- 2000-01-19 AU AU30460/00A patent/AU764725B2/en not_active Ceased
- 2000-01-19 DE DE60005154T patent/DE60005154T2/de not_active Expired - Lifetime
- 2000-01-19 AT AT00900518T patent/ATE249428T1/de not_active IP Right Cessation
- 2000-01-19 PT PT00900518T patent/PT1157987E/pt unknown
- 2000-01-19 GE GEAP20006075A patent/GEP20043220B/en unknown
- 2000-01-19 EP EP00900518A patent/EP1157987B1/en not_active Expired - Lifetime
- 2000-01-19 IL IL14438100A patent/IL144381A/xx not_active IP Right Cessation
- 2000-01-19 CZ CZ20012678A patent/CZ298871B6/cs not_active IP Right Cessation
- 2000-01-19 TR TR2001/02003T patent/TR200102003T2/xx unknown
- 2000-01-19 CA CA002359027A patent/CA2359027C/en not_active Expired - Fee Related
- 2000-01-19 RS YUP-536/01A patent/RS50072B/sr unknown
- 2000-01-19 EE EEP200100389A patent/EE04524B1/xx not_active IP Right Cessation
- 2000-01-19 ID IDW00200101662A patent/ID29777A/id unknown
- 2000-01-19 AP APAP/P/2001/002247A patent/AP1439A/en active
- 2000-01-19 CN CNB008030847A patent/CN1166631C/zh not_active Expired - Fee Related
- 2000-01-19 WO PCT/ES2000/000019 patent/WO2000044714A1/es active IP Right Grant
- 2000-01-19 BR BRPI0007395-4A patent/BR0007395B1/pt not_active IP Right Cessation
- 2000-01-19 PL PL349006A patent/PL202372B1/pl not_active IP Right Cessation
- 2000-01-19 OA OA1200100195A patent/OA11823A/en unknown
- 2000-01-19 NZ NZ513162A patent/NZ513162A/xx not_active IP Right Cessation
- 2000-01-19 DE DE10083902T patent/DE10083902T1/de not_active Ceased
- 2000-01-19 GB GB0120581A patent/GB2363604B/en not_active Expired - Fee Related
- 2000-01-19 SI SI200030236T patent/SI1157987T1/xx unknown
- 2000-01-19 KR KR1020017009522A patent/KR100671878B1/ko not_active IP Right Cessation
- 2000-01-19 MX MXPA01007570A patent/MXPA01007570A/es not_active IP Right Cessation
- 2000-01-19 ES ES00900518T patent/ES2206178T3/es not_active Expired - Lifetime
- 2000-01-19 HU HU0105203A patent/HUP0105203A3/hu unknown
- 2000-01-19 EA EA200100823A patent/EA003577B1/ru not_active IP Right Cessation
- 2000-01-19 DK DK00900518T patent/DK1157987T3/da active
-
2001
- 2001-07-06 NO NO20013385A patent/NO326806B1/no not_active IP Right Cessation
- 2001-07-23 IS IS6020A patent/IS2153B/is unknown
- 2001-07-24 US US09/912,164 patent/US6800612B2/en not_active Expired - Fee Related
- 2001-07-26 ZA ZA200106182A patent/ZA200106182B/en unknown
- 2001-07-26 HR HR20010562A patent/HRP20010562B1/xx not_active IP Right Cessation
- 2001-07-30 CU CU20010181A patent/CU23098A3/es not_active IP Right Cessation
- 2001-08-16 BG BG105824A patent/BG64983B1/bg unknown
-
2002
- 2002-05-28 HK HK02103982.2A patent/HK1043586A1/zh unknown
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