DK1181298T3 - Hidtil ukendte 15-leddede 8a- og 9a-lactamer - Google Patents

Hidtil ukendte 15-leddede 8a- og 9a-lactamer

Info

Publication number
DK1181298T3
DK1181298T3 DK00920937T DK00920937T DK1181298T3 DK 1181298 T3 DK1181298 T3 DK 1181298T3 DK 00920937 T DK00920937 T DK 00920937T DK 00920937 T DK00920937 T DK 00920937T DK 1181298 T3 DK1181298 T3 DK 1181298T3
Authority
DK
Denmark
Prior art keywords
lactams
membered
newly known
newly
Prior art date
Application number
DK00920937T
Other languages
Danish (da)
English (en)
Inventor
Gorjana Lazarevski
Stjepan Mutak
Sulejman Alihodzic
Gabrijela Kobrehel
Original Assignee
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Zagreb filed Critical Glaxosmithkline Zagreb
Application granted granted Critical
Publication of DK1181298T3 publication Critical patent/DK1181298T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK00920937T 1999-04-20 2000-04-19 Hidtil ukendte 15-leddede 8a- og 9a-lactamer DK1181298T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR990116A HRP990116B1 (en) 1999-04-20 1999-04-20 NOVEL 8a AND 9a- 15-MEMBERED LACTAMES

Publications (1)

Publication Number Publication Date
DK1181298T3 true DK1181298T3 (da) 2006-11-13

Family

ID=10946907

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00920937T DK1181298T3 (da) 1999-04-20 2000-04-19 Hidtil ukendte 15-leddede 8a- og 9a-lactamer

Country Status (33)

Country Link
US (1) US6593360B1 (ko)
EP (1) EP1181298B1 (ko)
JP (1) JP2002542254A (ko)
KR (1) KR20020007379A (ko)
CN (1) CN1246327C (ko)
AR (1) AR028823A1 (ko)
AT (1) ATE333461T1 (ko)
AU (1) AU772272B2 (ko)
BG (1) BG65281B1 (ko)
BR (1) BR0009943A (ko)
CA (1) CA2370273A1 (ko)
CZ (1) CZ20013730A3 (ko)
DE (1) DE60029439T2 (ko)
DK (1) DK1181298T3 (ko)
EA (1) EA003928B1 (ko)
EE (1) EE04553B1 (ko)
ES (1) ES2267519T3 (ko)
GE (1) GEP20032929B (ko)
HK (1) HK1049842B (ko)
HR (1) HRP990116B1 (ko)
HU (1) HUP0200868A3 (ko)
IL (1) IL145990A0 (ko)
IS (1) IS6110A (ko)
MX (1) MXPA01010627A (ko)
NO (1) NO320704B1 (ko)
NZ (1) NZ515279A (ko)
PL (1) PL351523A1 (ko)
PT (1) PT1181298E (ko)
SK (1) SK14942001A3 (ko)
TR (1) TR200103019T2 (ko)
UA (1) UA72246C2 (ko)
WO (1) WO2000063223A1 (ko)
ZA (1) ZA200108481B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides
HRP20020779A2 (en) 2002-09-27 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. NEW 3-DECLADINOSYL DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICIN A 9a, 11-CYCLIC CARBAMATES
US7435805B2 (en) * 2003-05-30 2008-10-14 Glaxpsmithkline Istrazivacki O-alkyl macrolide and azalide derivatives and regioselective process for their preparation
EP1879903A1 (en) 2005-05-10 2008-01-23 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Ether linked macrolides useful for the treatment of microbial infections
KR102363621B1 (ko) 2013-04-04 2022-02-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 매크롤라이드 그리고 그의 제조방법 및 용도
WO2016057798A1 (en) 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
US10640528B2 (en) 2015-03-25 2020-05-05 President And Fellows Of Havard College Macrolides with modified desosamine sugars and uses thereof
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
SI9011409A (en) * 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
JP2000509712A (ja) * 1996-05-07 2000-08-02 アボツト・ラボラトリーズ ６―ｏ―置換エリスロマイシン及びその製造方法
AU1082599A (en) * 1997-10-16 1999-05-03 Merck & Co., Inc. 8a-azalides, compositions containing such compounds and methods of treatment
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides

Also Published As

Publication number Publication date
NZ515279A (en) 2003-04-29
HUP0200868A2 (hu) 2002-07-29
IL145990A0 (en) 2002-07-25
US6593360B1 (en) 2003-07-15
EA200101103A1 (ru) 2002-04-25
EE200100544A (et) 2003-02-17
PT1181298E (pt) 2006-11-30
ES2267519T3 (es) 2007-03-16
BG65281B1 (bg) 2007-11-30
AU4134700A (en) 2000-11-02
NO20015068D0 (no) 2001-10-18
DE60029439D1 (de) 2006-08-31
HK1049842A1 (en) 2003-05-30
DE60029439T2 (de) 2007-02-01
HRP990116B1 (en) 2007-10-31
HUP0200868A3 (en) 2003-03-28
EE04553B1 (et) 2005-10-17
GEP20032929B (en) 2003-03-25
CN1362964A (zh) 2002-08-07
EP1181298A1 (en) 2002-02-27
EA003928B1 (ru) 2003-10-30
TR200103019T2 (tr) 2002-01-21
NO20015068L (no) 2001-12-13
PL351523A1 (en) 2003-05-05
KR20020007379A (ko) 2002-01-26
SK14942001A3 (sk) 2002-08-06
AR028823A1 (es) 2003-05-28
CZ20013730A3 (cs) 2002-04-17
ATE333461T1 (de) 2006-08-15
CA2370273A1 (en) 2000-10-26
JP2002542254A (ja) 2002-12-10
NO320704B1 (no) 2006-01-16
HRP990116A2 (en) 2001-10-31
BG106117A (en) 2002-07-31
AU772272B2 (en) 2004-04-22
HK1049842B (zh) 2006-09-22
BR0009943A (pt) 2002-01-08
MXPA01010627A (es) 2002-06-04
EP1181298B1 (en) 2006-07-19
WO2000063223A1 (en) 2000-10-26
ZA200108481B (en) 2003-03-26
UA72246C2 (uk) 2005-02-15
CN1246327C (zh) 2006-03-22
IS6110A (is) 2001-10-16

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