DK1353910T3 - Lactamforbindelse - Google Patents

Lactamforbindelse

Info

Publication number
DK1353910T3
DK1353910T3 DK01996530T DK01996530T DK1353910T3 DK 1353910 T3 DK1353910 T3 DK 1353910T3 DK 01996530 T DK01996530 T DK 01996530T DK 01996530 T DK01996530 T DK 01996530T DK 1353910 T3 DK1353910 T3 DK 1353910T3
Authority
DK
Denmark
Prior art keywords
lactam
Prior art date
Application number
DK01996530T
Other languages
English (en)
Inventor
Thomas Mitchell Koenig
James Edmund Audia
David Mitchell
Stacey Leigh Mcdaniel
Lynne Ann Buccilli
Gary Lowell Engel
James Abraham Aikins
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK1353910T3 publication Critical patent/DK1353910T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK01996530T 2000-11-17 2001-11-02 Lactamforbindelse DK1353910T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24965600P 2000-11-17 2000-11-17
PCT/US2001/027795 WO2002040451A2 (en) 2000-11-17 2001-11-02 Lactam compound

Publications (1)

Publication Number Publication Date
DK1353910T3 true DK1353910T3 (da) 2007-09-10

Family

ID=22944436

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01996530T DK1353910T3 (da) 2000-11-17 2001-11-02 Lactamforbindelse

Country Status (33)

Country Link
US (1) US20040248878A1 (da)
EP (1) EP1353910B1 (da)
JP (1) JP4116431B2 (da)
KR (1) KR20030045194A (da)
CN (2) CN101624372A (da)
AR (1) AR031356A1 (da)
AT (1) ATE362919T1 (da)
AU (2) AU2002224321B2 (da)
BR (1) BR0115424A (da)
CA (1) CA2425497C (da)
CY (1) CY1106682T1 (da)
CZ (1) CZ20031340A3 (da)
DE (1) DE60128587T2 (da)
DK (1) DK1353910T3 (da)
DZ (1) DZ3454A1 (da)
EA (1) EA006919B1 (da)
EC (1) ECSP034598A (da)
ES (1) ES2286162T3 (da)
HR (1) HRP20030385A2 (da)
HU (1) HUP0301862A3 (da)
IL (1) IL155275A0 (da)
MX (1) MXPA03004250A (da)
MY (1) MY141607A (da)
NO (1) NO325217B1 (da)
PE (1) PE20020798A1 (da)
PL (1) PL211018B1 (da)
PT (1) PT1353910E (da)
SK (1) SK287794B6 (da)
SV (1) SV2003000741A (da)
TW (1) TWI235151B (da)
UA (1) UA77165C2 (da)
WO (1) WO2002040451A2 (da)
ZA (1) ZA200303411B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA74849C2 (en) * 2000-11-17 2006-02-15 Lilly Co Eli Lactam
EP2133340B1 (en) 2002-12-20 2013-01-16 Glaxo Group Limited Novel benzazepine derivatives
BRPI0406761A (pt) 2003-01-14 2005-12-20 Arena Pharm Inc Derivados de arila e heteroarila 1,2,3-trissubstituìdos como moduladores do metabolismo e a profilaxia e tratamento de distúrbios relacionados a estes tais como diabetes e hiper-glicemia
US8114886B2 (en) 2005-04-08 2012-02-14 Daiichi Sankyo Company, Limited Pyridylmethylsulfone derivative
US8258302B2 (en) * 2006-01-31 2012-09-04 Api Corporation Method for producing benzazepinone
TW200920362A (en) 2007-09-11 2009-05-16 Daiichi Sankyo Co Ltd Alkylsulfone derivatives
FR2932800B1 (fr) * 2008-06-20 2015-02-20 Servier Lab Nouveau procede de synthese de la 7,8-dimethoxy-1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
AU2011305525B2 (en) 2010-09-22 2016-08-18 Arena Pharmaceuticals, Inc. Modulators of the GPR119 receptor and the treatment of disorders related thereto
KR101899014B1 (ko) 2012-01-06 2018-09-17 삼성전자주식회사 비엘디씨 모터의 제어 장치 및 그 방법
CN102690231B (zh) * 2012-04-11 2014-07-09 南京友杰医药科技有限公司 治疗阿尔茨海默病潜在药物司马西特的合成方法
JP6319912B2 (ja) 2013-04-19 2018-05-09 国立大学法人 岡山大学 アミロイドβ蛋白質により誘発される認知障害の治療剤およびアルツハイマー病治療薬、ならびにこれらに関連する治療方法および病態解析方法
AU2016205361C1 (en) 2015-01-06 2021-04-08 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
IL285890B (en) 2015-06-22 2022-07-01 Arena Pharm Inc Slate-free crystal of the arginine salt of (Ar)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-4,3,2,1-tetrahydro-cyclopent[b]indole-3-yl ) acetic acid
US11534424B2 (en) 2017-02-16 2022-12-27 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
IL296723A (en) 2020-03-26 2022-11-01 Seagen Inc Treatment methods for multiple myeloma

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3812952B2 (ja) * 1996-12-23 2006-08-23 エラン ファーマシューティカルズ,インコーポレイテッド シクロアルキル、ラクタム、ラクトンおよびその関連化合物およびその医薬組成物、並びに該化合物を用いたβ−アミロイドペプチドの放出および/またはその合成を阻害する方法
AU4707999A (en) * 1998-06-22 2000-01-10 Elan Pharmaceuticals, Inc. Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
WO2001034571A1 (en) * 1999-11-09 2001-05-17 Eli Lilly And Company β-AMINOACID COMPOUNDS USEFUL FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS

Also Published As

Publication number Publication date
CA2425497C (en) 2010-08-17
DE60128587T2 (de) 2008-01-31
CN100516047C (zh) 2009-07-22
EA006919B1 (ru) 2006-04-28
US20040248878A1 (en) 2004-12-09
SK5432003A3 (en) 2004-09-08
HRP20030385A2 (en) 2003-08-31
KR20030045194A (ko) 2003-06-09
DE60128587D1 (de) 2007-07-05
HUP0301862A2 (hu) 2003-09-29
EA200300579A1 (ru) 2003-12-25
TWI235151B (en) 2005-07-01
PL211018B1 (pl) 2012-03-30
ES2286162T3 (es) 2007-12-01
EP1353910B1 (en) 2007-05-23
PT1353910E (pt) 2007-08-20
JP4116431B2 (ja) 2008-07-09
NO20032215D0 (no) 2003-05-15
BR0115424A (pt) 2003-10-21
AR031356A1 (es) 2003-09-17
JP2004521084A (ja) 2004-07-15
ZA200303411B (en) 2004-08-02
WO2002040451A3 (en) 2003-08-28
SV2003000741A (es) 2003-01-13
DZ3454A1 (fr) 2002-05-23
MXPA03004250A (es) 2003-09-22
NO20032215L (no) 2003-07-16
EP1353910A2 (en) 2003-10-22
CY1106682T1 (el) 2012-05-23
SK287794B6 (sk) 2011-10-04
ECSP034598A (es) 2003-06-25
PE20020798A1 (es) 2002-09-06
CN1575282A (zh) 2005-02-02
UA77165C2 (en) 2006-11-15
CZ20031340A3 (cs) 2004-06-16
MY141607A (en) 2010-05-31
PL360991A1 (en) 2004-09-20
IL155275A0 (en) 2003-11-23
HUP0301862A3 (en) 2007-09-28
AU2432102A (en) 2002-05-27
WO2002040451A2 (en) 2002-05-23
CA2425497A1 (en) 2002-05-23
AU2002224321B2 (en) 2006-10-19
NO325217B1 (no) 2008-02-25
CN101624372A (zh) 2010-01-13
ATE362919T1 (de) 2007-06-15

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